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Journal Articles

Optimized CRISPR-Cas12a genome-wide screen reveals PTPA phosphatase pathway in fetal hemoglobin silencing

Elizabeth A. Traxler, Quynn Hotan, Yue Shao, Chad Komar, Qingzhou Chen, Megan S. Saari, A. Josephine Thrasher, Shuchen Yang, Kunhua Qin, Michelle Wang, Scott A. Peslak, Osheiza Abdulmalik, Belinda M. Giardine, Cheryl A. Keller, Ross C. Hardison, Andy J. Minn, Eugene Khandros, Junwei Shi, Gerd A. Blobel

Blood blood.2025030137.

https://doi.org/10.1182/blood.2025030137

Published: 2026

Includes: Supplemental data

Journal Articles

A Novel Genome-Scale CRISPR-Cas12a Screen Identifies Ptpa As a Fetal Hemoglobin Regulator Via BCL11A

Elizabeth A. Traxler, Chad Komar, Megan Saari, Quynn Hotan, A Josephine Thrasher, Eugene Khandros, Kunhua Qin, Osheiza Abdulmalik, Claire Shao, Qingzhou Chen, Andy J. Minn, Cheryl A. Keller, Junwei Shi, Gerd A. Blobel

Blood (2024) 144 (Supplement 1): 412.

https://doi.org/10.1182/blood-2024-210117

Published: 2024

Journal Articles

Genome-Scale CRISPR-Cas12a Screen Identifies Novel Fetal Hemoglobin Regulators

Elizabeth A. Traxler, Chad Komar, Megan Saari, A Josephine Thrasher, Kunhua Qin, Eugene Khandros, Quynn Hotan, Osheiza Abdulmalik, Claire Shao, Qingzhou Chen, Andy J. Minn, Cheryl A. Keller, Junwei Shi, Gerd A. Blobel

Blood (2023) 142 (Supplement 1): 1101.

https://doi.org/10.1182/blood-2023-189547

Published: 2023