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Journal Articles

Suppression of FVIII Antibody Production By FVIII BAR T-Cell in Vitro in the Presence of Inhibitors

Kalpana Parvathaneni, PhD, Ai-Hong Zhang, PhD, David W. Scott, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3789.
https://doi.org/10.1182/blood-2018-99-115278
Published: 2018
Journal Articles

FVIII-specific human chimeric antigen receptor T-regulatory cells suppress T- and B-cell responses to FVIII

Jeongheon Yoon, Anja Schmidt, Ai-Hong Zhang, Christoph Königs, Yong Chan Kim, David W. Scott
Journal: Blood
Blood (2017) 129 (2): 238–245.
https://doi.org/10.1182/blood-2016-07-727834
Published: 2017
Journal Articles

Targeting FVIII-Specific B Cells Using BAR-Transduced Regulatory T Cells

Ai-Hong Zhang, PhD, Jeong Heon Yoon, PhD, Yong Chan Kim, PhD, David W. Scott, PhD
Journal: Blood
Blood (2016) 128 (22): 329.
https://doi.org/10.1182/blood.V128.22.329.329
Published: 2016
Journal Articles

Mechanisms of Immunosuppression By FVIII-Specific TCR Engineered Human Regulatory T Cells

Yong Chan Kim, PhD, Ai-Hong Zhang, MS, PhD, Jeong Heon Yoon, PhD, David William Scott, PhD
Journal: Blood
Blood (2015) 126 (23): 3514.
https://doi.org/10.1182/blood.V126.23.3514.3514
Published: 2015
Journal Articles

Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses

Yong Chan Kim, Ai-Hong Zhang, Yan Su, Sadiye Amcaoglu Rieder, Robert J. Rossi, Ruth A. Ettinger, Kathleen P. Pratt, Ethan M. Shevach, David W. Scott
Journal: Blood
Blood (2015) 125 (7): 1107–1115.
https://doi.org/10.1182/blood-2014-04-566786
Published: 2015
Includes: Supplemental data
Journal Articles

Effect of B-cell depletion using anti-CD20 therapy on inhibitory antibody formation to human FVIII in hemophilia A mice

Ai-Hong Zhang, Jonathan Skupsky, David W. Scott
Journal: Blood
Blood (2011) 117 (7): 2223–2226.
https://doi.org/10.1182/blood-2010-06-293324
Published: 2011
Includes: Supplemental data
Journal Articles

B-Cell Depletion Using IgG1 Anti-CD20 Spares MZ B Cells and Promotes Tolerance to Human FVIII In a Murine Model of Hemophilia A

Ai-Hong Zhang, Ph.D., Jonathan Skupsky, PhD, David W. Scott, PhD
Journal: Blood
Blood (2010) 116 (21): 2206.
https://doi.org/10.1182/blood.V116.21.2206.2206
Published: 2010
Journal Articles

A role for thrombin in the initiation of the immune response to therapeutic factor VIII

Jonathan Skupsky, Ai-Hong Zhang, Yan Su, David W. Scott
Journal: Blood
Blood (2009) 114 (21): 4741–4748.
https://doi.org/10.1182/blood-2008-10-186452
Published: 2009
Includes: Supplemental data
Journal Articles

Unraveling the Danger Signal Necessary for the Immune Response to Therapeutic Factor VIII.

Jonathan Skupsky, BS, Ai-Hong Zhang, MS, PhD, David W. Scott, PhD
Journal: Blood
Blood (2008) 112 (11): 1220.
https://doi.org/10.1182/blood.V112.11.1220.1220
Published: 2008
Journal Articles

Induction of ‘Tolerance’ in a T-Cell Clone from a Mild Hemophilia Patient

David W. Scott, PhD, Elizabeth Kadavil, MSc, Ai-Hong Zhang, MS, PhD, Ruth A. Ettinger, PhD, Kathleen Pratt, PhD
Journal: Blood
Blood (2008) 112 (11): 3526.
https://doi.org/10.1182/blood.V112.11.3526.3526
Published: 2008