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Alessandra Pirola
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Journal Articles

Increased tumor burden in patients with chronic myeloid leukemia after 36 months of imatinib discontinuation

Clinical Trials & Observations
Elisa Diral, Silvia Mori, Laura Antolini, Elisabetta Abruzzese, Philipp Le Coutre, Bruno Martino, Ester Pungolino, Chiara Elena, Micaela Bergamaschi, Sarit Assouline, Eros Di Bona, Antonella Gozzini, Marcio Andrade-Campos, Fabio Stagno, Alessandra Iurlo, Alessandra Pirola, Diletta Fontana, Jessica Petiti, Maria Luisa Bonanomi, Patrizia Crivori, Rocco Piazza, Carmen Fava, Carlo Gambacorti-Passerini
Journal: Blood
Blood (2020) 136 (19): 2237–2240.
https://doi.org/10.1182/blood.2019004371
Published: 2020
Includes: Supplemental data
Journal Articles

Increased Tumour Burden over a 36 Month Period in Chronic Myeloid Leukemia Patients Following Imatinib Discontinuation: Role of Digital PCR

Elisa Diral, MD, Philipp Le Coutre, MD, Enrico Marco Gottardi, Chiara Elena, MD, Micaela Bergamaschi, MD, Sarit Assouline, MD, Eros Di Bona, MD, Jessica Petiti, PhD, Fabio Stagno, MD, Alessandra Iurlo, MD PhD, Dong-Wook Kim, Alessandra Pirola, MSc, Maria Luisa Bonanomi, Patrizia Crivori, PhD, Rocco Piazza, MD PhD, Carmen Fava, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 29.
https://doi.org/10.1182/blood-2019-125226
Published: 2019
Journal Articles

Imatinib Suspension and Validation (ISAV) Study: Final Results at 79 Months

Silvia Mori, PhD, Philipp le Coutre, MD, Elisabetta Abruzzese, Bruno Martino, MD, Ester Pungolino, Chiara Elena, MD, Micaela Bergamaschi, MD, Sarit Assouline, Eros Di Bona, MD, Antonella Gozzini, MD, Marcio Andrade, MD, Fabio Stagno, Alessandra Iurlo, Dong-Wook Kim, MD PhD, Michela Luciani, RN, PhD, Alessandra Pirola, M.Sc., Maria Luisa Bonanomi, Patrizia Crivori, PhD, Rocco Piazza, MD PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 461.
https://doi.org/10.1182/blood-2018-99-112982
Published: 2018
Journal Articles

De Novo UBE2A Mutations Are Recurrently Acquired during CML Progression and Interfere with Myeloid Differentiation Pathways

VERA Magistroni, PhD, Rocco Piazza, MD PhD, Mario Mauri, PhD, Caterina Mezzatesta, M.Sc., Nitesh Sharma, PhD, Wendy Parker, PhD, Andreas Schreiber, PhD, David T Yeung, PhDBSc,FRACP,FRCPA,MBBS, Sara Redaelli, PhD, Paul Wang, Alessandra Pirola, M.Sc., Luca Massimino, PhD, Praveen Khandelwal, Stefania Citterio, Michela Viltadi, Jacqueline Boultwood, PhD, Alessandro Morotti, MD PhD, Giuseppe Saglio, MD PhD, Dong-Wook Kim, MD PhD, Susan Branford, PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 44.
https://doi.org/10.1182/blood.V130.Suppl_1.44.44
Published: 2017
Journal Articles

Imatinib Suspension and Validation Study: Results from the Isav Study at 62 Months

Silvia Mori, PhD, Philipp D. le Coutre, MD, Elisabetta Abruzzese, MD, Bruno Martino, Ester Pungolino, Chiara Elena, Micaela Bergamaschi, MD, Sarit Assouline, MD, Eros Di Bona, MD, Antonella Gozzini, MD, Marcio Andrade, Fabio Stagno, MD PhD, Alessandra Iurlo, MD PhD, Michela Luciani, Eleonora Parisse, Dong-Wook Kim, MD PhD, Alessandra Pirola, M.Sc., Michela Viltadi, Maria Luisa Bonanomi, Patrizia Crivori, Rocco Piazza, MD PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2870.
https://doi.org/10.1182/blood.V130.Suppl_1.2870.2870
Published: 2017
Journal Articles

Identification of SETBP1 As an Epigenetic Hub Protein That Induces the Transcription of a Network of Development-Related Genes

Rocco Piazza, MD PhD, VERA Magistroni, PhD, Sara Redaelli, PhD, Mario Mauri, PhD, Luca Massimino, PhD, Alessandro Sessa, PhD, Marco Peronaci, PhD, Maciej Lalowski, PhD, Rabah Soliymani, PhD, Caterina Mezzatesta, M.Sc., Alessandra Pirola, M.Sc., Federica Banfi, M.Sc., Alicia Rubio, PhD, Delphine Rea, MD, Fabio Stagno, MD PhD, Emilio Usala, MD, Bruno Martino, Leonardo Campiotti, MD, Michele Merli, Francesco Passamonti, MD, Francesco Onida, MD, Alessandro Morotti, MD PhD, Francesca Pavesi, MD, Marco Bregni, MD, Vania Broccoli, PhD, Marc Baumann, MBA, MB, PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4980.
https://doi.org/10.1182/blood.V130.Suppl_1.4980.4980
Published: 2017
Journal Articles

Oncoscore, a Novel, Internet-Based Tool to Assess the Oncogenic Potential of Genes Can Differentiate Between CP-CML and BC-CML Associated Genes, and Between CP-CML Patients with Good and Bad Prognosis

Rocco Piazza, MD PhD, Luca Mologni, PhD, Daniele Ramazzotti, PhD, Roberta Spinelli, MSc, Alessandra Pirola, MSc, Luca De Sano, MSc, Pierangelo Ferrari, Vera Magistroni, PhD, Nitesh Sharma, PhD, Praveen Khandelwal, PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2016) 128 (22): 3075.
https://doi.org/10.1182/blood.V128.22.3075.3075
Published: 2016
Journal Articles

Synergistic Activity of ALK and mTOR Inhibitors for the Treatment of NPM-ALK Positive Lymphoma

Sara Redaelli, PhD, Monica Ceccon, PhD, Alessandra Pirola, MSc, Marco Peronaci, MSc, Carlo Gambacorti-Passerini, MD, Luca Mologni, PhD
Journal: Blood
Blood (2015) 126 (23): 3710.
https://doi.org/10.1182/blood.V126.23.3710.3710
Published: 2015
Journal Articles

ETNK1 Is an Early Event and SETBP1 a Late Event in Atypical Chronic Myeloid Leukemia

Antonio Niro, Rocco Piazza, MDPhD, Gabriele Merati, Alessandra Pirola, MSc, Carla Donadoni, MSc, PhD, Diletta Fontana, MSc, Sara Redaelli, PhD, Caterina Mezzatesta, Rossella Renso, MD, Francesca Farina, MD, Delphine Rea, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2015) 126 (23): 3652.
https://doi.org/10.1182/blood.V126.23.3652.3652
Published: 2015
Journal Articles

Imatinib Suspension and Validation (ISAV) Study: Results at 24 Months

Silvia Mori, PhD, Philipp le Coutre, MD, Elisabetta Abruzzese, MD, Bruno Martino, MD, Ester Pungolino, MD, Chiara Elena, MD, Ivana Pierri, MD, Sarit E. Assouline, MDMSc, Anna D'Emilio, MD, Antonella Gozzini, MD, Pilar Giraldo, MD PhD, Fabio Stagno, MD PhD, Alessandra Iurlo, MD PhD, Andrea Aroldi, MD, Michela Luciani, RN, Giulia De Riso, RN, Kim Dong-Wook, MD PhD, Alessandra Pirola, MSc, Anna Petroccione, Maria Luisa Bonanomi, Patrizia Crivori, PhD, Rocco Piazza, MDPhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2015) 126 (23): 2775.
https://doi.org/10.1182/blood.V126.23.2775.2775
Published: 2015
Journal Articles

Recurrent ETNK1 mutations in atypical chronic myeloid leukemia

Carlo B. Gambacorti-Passerini, Carla Donadoni, Andrea Parmiani, Alessandra Pirola, Sara Redaelli, Giovanni Signore, Vincenzo Piazza, Luca Malcovati, Diletta Fontana, Roberta Spinelli, Vera Magistroni, Giuseppe Gaipa, Marco Peronaci, Alessandro Morotti, Cristina Panuzzo, Giuseppe Saglio, Emilio Usala, Dong-Wook Kim, Delphine Rea, Konstantinos Zervakis, Nora Viniou, Argiris Symeonidis, Heiko Becker, Jacqueline Boultwood, Leonardo Campiotti, Matteo Carrabba, Elena Elli, Graham R. Bignell, Elli Papaemmanuil, Peter J. Campbell, Mario Cazzola, Rocco Piazza
Journal: Blood
Blood (2015) 125 (3): 499–503.
https://doi.org/10.1182/blood-2014-06-579466
Published: 2015
Includes: Supplemental data
Journal Articles

The Risk of Relapse in CML Patients Who Discontinued imatinib Can Be Predicted Based on Patients Age and the Results of dPCR Analysis

Silvia Mori, PhD, Elisabetta Vagge, MD, Philipp le Coutre, MD, Elisabetta Abruzzese, MD, Bruno Martino, MD, Ester Pungolino, MD, Chiara Elena, MD, Ivana Pierri, MD, Sarit Assouline, MD MSc, Anna D'Emilio, MD, Antonella Gozzini, MD, Pilar Giraldo, MD PhD, Fabio Stagno, MD PhD, Alessandra Iurlo, MD PhD, Michela Luciani, RN, Giulia De Riso, RN, Kim Dong-Wook, MD PhD, Alessandra Pirola, M.Sc., Anna Petroccione, Agnese Lodolo D'Oria, Patrizia Crivori, PhD, Rocco Piazza, MD PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2014) 124 (21): 813.
https://doi.org/10.1182/blood.V124.21.813.813
Published: 2014
Journal Articles

Recurrent KIT D816V Mutation in Atypical Chronic Myeloid Leukemia

Sara Redaelli, PhD, Rocco Piazza, MD PhD, Alessandra Pirola, M.Sc., Vera Magistroni, PhD, Susanne Schnittger, PhD, Manja Meggendorfer, PhD, Nicholas C.P. Cross, PhD, Delphine Rea, MD PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2014) 124 (21): 3576.
https://doi.org/10.1182/blood.V124.21.3576.3576
Published: 2014
Journal Articles

Evidence of ETNK1 Somatic Variants in Atypical Chronic Myeloid Leukemia

Carla Donadoni, PhD, Rocco Piazza, MD PhD, Diletta Fontana, M.Sc., Andrea Parmiani, M.Sc., Alessandra Pirola, M.Sc., Sara Redaelli, PhD, Giovanni Signore, M.Sc., Vincenzo Piazza, PhD, Luca Malcovati, MD, Roberta Spinelli, M.Sc., Vera Magistroni, PhD, Giuseppe Gaipa, Marco Peronaci, M.Sc., Alessandro Morotti, MDPhD, Cristina Panuzzo, PhD, Giuseppe Saglio, MD, Elena Maria Elli, MD, Emilio Usala, MD, Dong-Wook Kim, MD PhD, Delphine Rea, MDPhD, Konstantinos Zervakis, MD, Nora-Athina Viniou, MD, Argiris Symeonidis, MD, Heiko Becker, MD, Jacqueline Boultwood, PhD, Leonardo Campiotti, MD, Matteo G Carrabba, MD, Graham R Bignell, PhD, Elli Papaemmanuil, PhD, Peter J Campbell, PhD, Mario Cazzola, MD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2014) 124 (21): 2212.
https://doi.org/10.1182/blood.V124.21.2212.2212
Published: 2014
Journal Articles

Validation of Digital-PCR Analysis through Programmed imatinib Interruption in Q-RT-PCR Negative Chronic Myeloid Leukemia Patients

Silvia Mori, PhD, Elisabetta Vagge, Philipp le Coutre, MD, Elisabetta Abruzzese, Bruno Martino, MD, Ester Pungolino, MD, Chiara Elena, MD, Ivana Pierri, MD, Sarit Assouline, MD, Anna D'Emilio, MD, Antonella Gozzini, MD, Pilar Giraldo, MD PhD, Fabio Stagno, MD, Arnon Nagler, MD, MSc, Alessandra Iurlo, MD, Christian Rizzo, Alessia Fossati, Enrico Maria Pogliani, MD, Dong-Wook Kim, MD, PhD, Alessandra Pirola, M.Sc., Rocco Piazza, MD, PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2013) 122 (21): 4040.
https://doi.org/10.1182/blood.V122.21.4040.4040
Published: 2013
Journal Articles

SETBP1 and CSF3R Mutations In Atypical Chronic Myeloid Leukemia

Rocco Piazza, MD, PhD, Sara Redaelli, PhD, Simona Valletta, Alessandra Pirola, M.Sc., Roberta Spinelli, M.Sc., Vera Magistroni, PhD, Dong-Wook Kim, MD, PhD, Nicholas C.P. Cross, PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2013) 122 (21): 2598.
https://doi.org/10.1182/blood.V122.21.2598.2598
Published: 2013
Journal Articles

Integrated Analysis of Whole-Exome Sequencing and Micrornas Expression in Blast Crisis Transformation of Chronic Myeloid Leukemia

Vera Magistroni, PhD, Nitesh Sharma, Rocco Piazza, MD, PhD, Jason G Harb, Ph.D, Roberta Spinelli, M.Sc., Alessandra Pirola, M.Sc., Justin Ellis, Kim Dong-Wook, Danilo Perrotti, MD, Ph.D, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2012) 120 (21): 3727.
https://doi.org/10.1182/blood.V120.21.3727.3727
Published: 2012
Journal Articles

Recurrent SETBP1 Mutations in Atypical Chronic Myeloid Leukemia Abrogate an Ubiquitination Site and Dysregulate SETBP1 Protein Levels

Carlo Gambacorti-Passerini, MD, Simona Valletta, Nils Winkelmann, MD, Sara Redaelli, PhD, Roberta Spinelli, M.Sc., Alessandra Pirola, M.Sc., Laura Antolini, Luca Mologni, PhD, Carla Donadoni, Elli Papaemmanuil, PhD, Susanne Schnittger, PhD, Kim Dong-Wook, Jacqueline Boultwood, MD, Fabio Rossi, Giuseppe Gaipa, PhD, Greta De Martini, MD, Paola Francia di Celle, PhD, Hyun G. Jang, Valeria Fantin, PhD, Graham R Bignell, Vera Magistroni, PhD, Torsten Haferlach, MD, Enrico Maria Pogliani, MD, Peter Campbell, MD Phd, Andrew J Chase, PhD, William J Tapper, PhD, Nicholas C.P. Cross, PhD, FRCPath, Rocco Piazza, MD, PhD
Journal: Blood
Blood (2012) 120 (21): LBA-2.
https://doi.org/10.1182/blood.V120.21.LBA-2.LBA-2
Published: 2012
Journal Articles

Whole-Exome Sequencing of 8 Atypical Chronic Myeloid Leukaemia Patients,

Rocco Piazza, MD, PhD, Simona Valletta, M.Sc., Alessandra Pirola, M.Sc., Hima Raman, M.Sc., Roberta Spinelli, M.Sc., Nick C.P. Cross, PhD, Caterina Cecchetti, MD, Zaira Sortino, B.Sc., Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2011) 118 (21): 3853.
https://doi.org/10.1182/blood.V118.21.3853.3853
Published: 2011
Journal Articles

CML Patients Present Additional Mutations in Cancer Related Genes When Tested At Diagnosis

Carlo Gambacorti-Passerini, MD, Simona Valletta, M.Sc., Alessandra Stasia, MD, Alexander Leeksma, Nitesh Sharma, Christian Rizzo, Enrico Maria Pogliani, MD, Alessandra Pirola, M.Sc., Rocco Piazza, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2739.
https://doi.org/10.1182/blood.V118.21.2739.2739
Published: 2011