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Alexandra Leutbecher
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Journal Articles

T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals

Nora Philipp, Maryam Kazerani, Alyssa Nicholls, Binje Vick, Jan Wulf, Tobias Straub, Michaela Scheurer, Amelie Muth, Gerulf Hänel, Daniel Nixdorf, Monika Sponheimer, Malte Ohlmeyer, Sonja M. Lacher, Bettina Brauchle, Anetta Marcinek, Lisa Rohrbacher, Alexandra Leutbecher, Kai Rejeski, Oliver Weigert, Michael von Bergwelt-Baildon, Sebastian Theurich, Roman Kischel, Irmela Jeremias, Veit Bücklein, Marion Subklewe
Journal: Blood
Blood (2022) 140 (10): 1104–1118.
https://doi.org/10.1182/blood.2022015956
Published: 2022
Includes: Supplemental data
Journal Articles

Treatment-Free Intervals during CD19xCD3 BiTE ® Construct-Mediated T-Cell Stimulation Induce Functional Reinvigoration and Transcriptional Reprogramming of Exhausted T Cells

Nora Zieger, Maryam Kazerani Pasikhani, Tobias Straub, Alyssa Nicholls, Gerulf Hänel, Jan Wulf, Michaela Scheurer, Daniel Nixdorf, Monika Sponheimer, Sonja M Lacher, Bettina Brauchle, Anetta Marcinek, Lisa Rohrbacher, Alexandra Leutbecher, Michael von Bergwelt, Karsten Spiekermann, Oliver Weigert, Sebastian Theurich, Veit L Buecklein, Roman Kischel, Marion Subklewe
Journal: Blood
Blood (2021) 138 (Supplement 1): 513.
https://doi.org/10.1182/blood-2021-150178
Published: 2021
Journal Articles

Augmenting Efficacy of T-Cell Bispecific Antibodies in AML through a Tumor Stroma-Targeted 4-1BB Agonist

Gerulf Hänel, Anne-Sophie Neumann, Vesna Pulko, Christina Claus, Alexandra Leutbecher, Anetta Marcinek, Nora Zieger, Veit L Buecklein, Pablo Umana, Christian Klein, Marion Subklewe
Journal: Blood
Blood (2021) 138 (Supplement 1): 1178.
https://doi.org/10.1182/blood-2021-146762
Published: 2021