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Tobias Straub
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Journal Articles

Two Players, One Goal: BiTE ® Vs CART Targeting FLT3 in AML

Lisa Rohrbacher, Daniel Nixdorf, Helena Stadler, Bettina Brauchle, Florian Märkl, Nora Philipp, Gerulf Hänel, Anetta Marcinek, Maryam Kazerani, Alica Joana Emhardt, Giulia Magno, Rebecca L. Goldstein, Tobias Straub, Sebastian Kobold, Tara L. Chapman-Arvedson, Veit L. Buecklein, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 3444.
https://doi.org/10.1182/blood-2023-177922
Published: 2023
Journal Articles

Beyond Mitigating Immune-Related Adverse Events: Glucocorticoids Ameliorate Bispecific Antibody-Mediated T-Cell Exhaustion I n Vitro

Amelie Muth, Nora Philipp, Anetta Marcinek, Tobias Straub, Lis Winter, Gerulf Hänel, Daniel Nixdorf, Lisa Rohrbacher, Veit L. Buecklein, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 5389.
https://doi.org/10.1182/blood-2023-174258
Published: 2023
Journal Articles

Single-Cell Transcriptomic Profiling of T Cells from Blinatumomab-Treated Patients with B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Reveals Circulating CD8 T Cell Subsets Associated with Treatment Response

Francesco Corrado, Jan Wulf, Tobias Straub, Daniel Nixdorf, Anetta Marcinek, Nora Philipp, Chang-Feng Chu, Christina Zielinski, Michael von Bergwelt-Baildon, Viktoria Blumenberg, Maryam Kazerani, Marion Subklewe, Veit L. Buecklein
Journal: Blood
Blood (2023) 142 (Supplement 1): 600.
https://doi.org/10.1182/blood-2023-188970
Published: 2023
Journal Articles

Phenotypic, Transcriptomic and Proteomic Characteristics of CAR T-Cell Dysfunction Are Associated with Inferior CAR T-Cell Expansion and Treatment Failure in r/r B-NHL

Viktoria Blumenberg, Maryam Kazerani, Stephan Baumann, Tobias Straub, Francesco Corrado, Jan Wulf, Galina Busch, Kai Rejeski, Lisa Frölich, Christian Schmidt, Michael von Bergwelt-Baildon, Veit L. Buecklein, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 3439.
https://doi.org/10.1182/blood-2023-187495
Published: 2023
Journal Articles

T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals

Nora Philipp, Maryam Kazerani, Alyssa Nicholls, Binje Vick, Jan Wulf, Tobias Straub, Michaela Scheurer, Amelie Muth, Gerulf Hänel, Daniel Nixdorf, Monika Sponheimer, Malte Ohlmeyer, Sonja M. Lacher, Bettina Brauchle, Anetta Marcinek, Lisa Rohrbacher, Alexandra Leutbecher, Kai Rejeski, Oliver Weigert, Michael von Bergwelt-Baildon, Sebastian Theurich, Roman Kischel, Irmela Jeremias, Veit Bücklein, Marion Subklewe
Journal: Blood
Blood (2022) 140 (10): 1104–1118.
https://doi.org/10.1182/blood.2022015956
Published: 2022
Includes: Supplemental data
Journal Articles

Evolving Exhaustion of T Cells during the Course of the Disease in AML Can be Abrogated By CD33 BiTE ® Construct Mediated Cytotoxicity

Maryam Kazerani Pasikhani, Anetta Marcinek, Bettina Brauchle, Jonathan Jonas Taylor, Helena Domínguez Moreno, Maria Solovey, Frank Ziemann, Nora Zieger, Andrea Terrasi, Benjamin Tast, Karsten Spiekermann, Klaus H. Metzeler, Tobias Straub, Gunnar Schotta, Roman Kischel, Veit L Buecklein, Marion Subklewe
Journal: Blood
Blood (2021) 138 (Supplement 1): 1172.
https://doi.org/10.1182/blood-2021-150351
Published: 2021
Journal Articles

Treatment-Free Intervals during CD19xCD3 BiTE ® Construct-Mediated T-Cell Stimulation Induce Functional Reinvigoration and Transcriptional Reprogramming of Exhausted T Cells

Nora Zieger, Maryam Kazerani Pasikhani, Tobias Straub, Alyssa Nicholls, Gerulf Hänel, Jan Wulf, Michaela Scheurer, Daniel Nixdorf, Monika Sponheimer, Sonja M Lacher, Bettina Brauchle, Anetta Marcinek, Lisa Rohrbacher, Alexandra Leutbecher, Michael von Bergwelt, Karsten Spiekermann, Oliver Weigert, Sebastian Theurich, Veit L Buecklein, Roman Kischel, Marion Subklewe
Journal: Blood
Blood (2021) 138 (Supplement 1): 513.
https://doi.org/10.1182/blood-2021-150178
Published: 2021