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Alexandria van Scoyk
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Journal Articles

Cellular Plasticity As Mechanisms to Escape from NOTCH1-Inhibition in T-ALL

Valeriya Dimitrova, Noori Sotudeh, Birgit Knoechel, Jens G. Lohr, Anna Montanaro, Sayalee V. Potdar, Julia Frede, Alexandria Van Scoyk, Shruti Bhatt, Praveen Anand, Jon C. Aster, David M Weinstock, Anthony G. Letai
Journal: Blood
Blood (2022) 140 (Supplement 1): 3461–3462.
https://doi.org/10.1182/blood-2022-170319
Published: 2022
Journal Articles

Maturity State and MCL-1 Dependence Predetermines Response to NOTCH1 Inhibition in T-ALL

Valeriya Dimitrova, Noori Sotudeh, Anna Montanaro, Huiyoung Yun, Sayalee V. Potdar, Alexandria Van Scoyk, Shruti Bhatt, Praveen Anand, Antonis Kokkalis, Jake A. Kloeber, Julia Frede, Johannes M Waldschmidt, Anthony G. Letai, David M. Weinstock, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2021) 138 (Supplement 1): 3484.
https://doi.org/10.1182/blood-2021-153829
Published: 2021
Journal Articles

Exploiting LY3009120 and Asciminib Combination to Target TKI-Resistant CML

Milad Rouhimoghadam, Anthony D. Pomicter, Alexandria Van Scoyk, Greg Poffenberger, Ivaylo Kirov, Lyubomir G. Nashev, Helong Zhao, Martin Martinov, Michael W. Deininger
Journal: Blood
Blood (2021) 138 (Supplement 1): 3600.
https://doi.org/10.1182/blood-2021-153353
Published: 2021
Journal Articles

Targeted inhibition of CD47-SIRPα requires Fc-FcγR interactions to maximize activity in T-cell lymphomas

Salvia Jain, Alexandria Van Scoyk, Elizabeth A. Morgan, Andrew Matthews, Kristen Stevenson, Gail Newton, Foster Powers, Anu Autio, Abner Louissaint, Jr, Guillemette Pontini, Jon C. Aster, Francis W. Luscinskas, David M. Weinstock
Journal: Blood
Blood (2019) 134 (17): 1430–1440.
https://doi.org/10.1182/blood.2019001744
Published: 2019
Includes: Supplemental data
Journal Articles

Biomarker-driven strategy for MCL1 inhibition in T-cell lymphomas

Raphael Koch, Amanda L. Christie, Jennifer L. Crombie, Adam C. Palmer, Deborah Plana, Kay Shigemori, Sara N. Morrow, Alexandria Van Scoyk, Wenchao Wu, Elizabeth A. Brem, J. Paul Secrist, Lisa Drew, Alwin G. Schuller, Justin Cidado, Anthony Letai, David M. Weinstock
Journal: Blood
Blood (2019) 133 (6): 566–575.
https://doi.org/10.1182/blood-2018-07-865527
Published: 2019
Includes: Supplemental data
Journal Articles

Targeted Inhibition of CD47-Sirp Alpha Requires Fc-Fc Gamma Receptor Interactions to Maximize Phagocytosis in T-Cell Lymphomas

Salvia Jain, MD, Alexandria Van Scoyk, Elizabeth A Morgan, MD, Andrew Matthews, MD, Kristen E. Stevenson, MS, Gail Newton, PhD, Anu K Autio, PhD, Marisa O. Peluso, MS, Rachel W O'Connor, BS, Alison M. Paterson, PhD, Pamela M. Holland, PhD, Francis W Luscinskas, PhD, David M Weinstock, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 339.
https://doi.org/10.1182/blood-2018-99-112986
Published: 2018
Journal Articles

Anti-CD37 chimeric antigen receptor T cells are active against B- and T-cell lymphomas

Irene Scarfò, Maria Ormhøj, Matthew J. Frigault, Ana P. Castano, Selena Lorrey, Amanda A. Bouffard, Alexandria van Scoyk, Scott J. Rodig, Alexandra J. Shay, Jon C. Aster, Frederic I. Preffer, David M. Weinstock, Marcela V. Maus
Journal: Blood
Blood (2018) 132 (14): 1495–1506.
https://doi.org/10.1182/blood-2018-04-842708
Published: 2018
Includes: Supplemental data
Journal Articles

In Vitro andpre-Clinical In Vivo evidence Support MDMX/MDM2 As Common Vulnerabilities across TP53 -Wild-Type T-Cell Lymphomas That Are Targetable with the α-Helical p53 Stapled Peptide Alrn-6924

Raphael Koch, MD, Amanda L Christie, BS, Noriaki Yoshida, MD PhD, Samuel Y. Ng, MDPhD, Kay Shigemori, Sara N Morrow, Alexandria Van Scoyk, Steven M. Horwitz, MD, Eric Jacobsen, MD, Solimar Santiago, Jian-Guo Ren, Vincent Guerlavais, PhD, D. Allan Annis, Manuel A. Aivado, MD PhD, David M. Weinstock, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 571.
https://doi.org/10.1182/blood.V130.Suppl_1.571.571
Published: 2017