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Journal Articles

BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone

Toril Holien, PhD, Marita Westhrin, PhD, Siv Helen Moen, PhD, Muhammad Zahoor, PhD, Glenn Buene, Berit Størdal, Hanne Hella, Huipin Yuan, Joost D de Bruijn, PhD, Anton Martens, PhD, Richard WJ Groen, PhD, Fatima Bosch, PhD, Ulf Smith, MD PhD, Anders Sundan, PhD, Therese Standal, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1928.
https://doi.org/10.1182/blood-2018-99-112429
Published: 2018
Journal Articles

Establishing Human Niche Xenograft Models For Myeloid and Lymphoid Leukemia Driven By MLL-AF9

Marco Carretta, Jennifer Jaques, Yuan Huipin, Anton Martens, PhD, Edo Vellenga, MD, PhD, Richard Groen, Jan Jacob Schuringa, PhD
Journal: Blood
Blood (2013) 122 (21): 1646.
https://doi.org/10.1182/blood.V122.21.1646.1646
Published: 2013
Journal Articles

Disregulated Osteogenesis By Mesenchymal Stromal Cells (MSC) After In Vivo Exposure To Multiple Myeloma: Studies In a Novel Humanized Mouse Model For Bone Remodelling In Myeloma

Richard W.J. Groen, PhD, Willy A. Noort, PhD, Jessica Sigmans, Aniek van Stralen, Linda Aalders, Reinier Raymakers, MD, PhD, Huipin Yuan, PhD, Constantine S. Mitsiades, MD, PhD, Anton Martens, PhD
Journal: Blood
Blood (2013) 122 (21): 1906.
https://doi.org/10.1182/blood.V122.21.1906.1906
Published: 2013
Journal Articles

The Survivin Suppressant YM155 Overcomes Microenvironment-Mediated Immune Resistance In a Humanized Multiple Myeloma Mouse Model

Sanne J. de Haart, MD, Monique C. Minnema, MD PhD, Julie H. Huang, PhD, Tineke Aarts-Riemens, Henk Lokhorst, Anton Martens, PhD, Constantine S. Mitsiades, MD, PhD, Tuna Mutis, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3250.
https://doi.org/10.1182/blood.V122.21.3250.3250
Published: 2013
Journal Articles

CD38-Targeted Immunochemotherapy Of Multiple Myeloma: Preclinical Evidence For Its Combinatorial Use In Lenalidomide and Bortezomib Refractory/Intolerant MM Patients

Inger S. Nijhof, MD, Willy A. Noort, PhD, Jeroen Lammerts van Bueren, PhD, Berris van Kessel, Joost M. Bakker, PhD, Paul W.H.I. Parren, PhD, Richard W.J. Groen, PhD, Niels W.C.J. van de Donk, MD, PhD, Henk Lokhorst, Tuna Mutis, MD, PhD, Anton Martens, PhD
Journal: Blood
Blood (2013) 122 (21): 277.
https://doi.org/10.1182/blood.V122.21.277.277
Published: 2013
Journal Articles

Mouse Versus Human Extrinsic Cues Dictate Transformation Potential In BCR-ABL/BMI1-Induced Leukemia In Humanized Xenograft Models

Pallavi Sontakke, Richard W.J. Groen, PhD, Jennifer Jaques, Huipin Yuan, PhD, Anton Martens, PhD, Edo Vellenga, MD, PhD, Jan Jacob Schuringa, PhD
Journal: Blood
Blood (2013) 122 (21): 515.
https://doi.org/10.1182/blood.V122.21.515.515
Published: 2013
Journal Articles

γ9 and δ2CDR3 domains regulate functional avidity of T cells harboring γ9δ2TCRs

Cordula Gründer, Suzanne van Dorp, Samantha Hol, Esther Drent, Trudy Straetemans, Sabine Heijhuurs, Kirsten Scholten, Wouter Scheper, Zsolt Sebestyen, Anton Martens, Roland Strong, Jürgen Kuball
Journal: Blood
Blood (2012) 120 (26): 5153–5162.
https://doi.org/10.1182/blood-2012-05-432427
Published: 2012
Includes: Supplemental data
Journal Articles

Redirecting αβT cells against cancer cells by transfer of a broadly tumor-reactive γδT-cell receptor

Victoria Marcu-Malina, Sabine Heijhuurs, Marit van Buuren, Linda Hartkamp, Susanne Strand, Zsolt Sebestyen, Kirsten Scholten, Anton Martens, Jürgen Kuball
Journal: Blood
Blood (2011) 118 (1): 50–59.
https://doi.org/10.1182/blood-2010-12-325993
Published: 2011
Includes: Supplemental data
Journal Articles

Bone Marrow Neutralizes Human Regulatory T-Cells to Permit Graft-Versus-Tumor Immunity In Humanized Mice

Teun Guichelaar, PhD, Henk Rozemuller, PhD, Maarten Emmelot, Bianka Martini, Gert Storm, Henk M Lokhorst, MD, PhD, Anton Martens, PhD, Tuna Mutis, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1017.
https://doi.org/10.1182/blood.V116.21.1017.1017
Published: 2010
Journal Articles

In Vitro and In Vivo Efficacy of CD38 Directed Therapy with Daratumumab In the Treatment of Multiple Myeloma

Richard W Groen, Michael van der Veer, Frans M Hofhuis, Berris van Kessel, Michel de Weers, PhD, Paul W.H.I. Parren, PhD, Henk M Lokhorst, MD, PhD, Tuna Mutis, MD, PhD, Anton Martens, PhD
Journal: Blood
Blood (2010) 116 (21): 3058.
https://doi.org/10.1182/blood.V116.21.3058.3058
Published: 2010
Journal Articles

Autologous bone marrow transplantation in autoimmune arthritis restores immune homeostasis through CD4 + CD25 + Foxp3 + regulatory T cells

Sarah T. A. Roord, Wilco de Jager, Louis Boon, Nico Wulffraat, Anton Martens, Berent Prakken, Femke van Wijk
Journal: Blood
Blood (2008) 111 (10): 5233–5241.
https://doi.org/10.1182/blood-2007-12-128488
Published: 2008
Journal Articles

The In Vivo Impact of Human Regulatory T Cells on the Graft Versus Tumor Effect.

Tuna Mutis, MD, PhD, Henk Rozemuller, PhD, Maarten E. Emmelot, Tineke Aarts-Riemens, Vivienne Verweij, Saskia Ebeling, PhD, Leo F. Verdonck, MD, PhD, Henk Lockhorst, MD, PhD, Anton Martens, PhD
Journal: Blood
Blood (2007) 110 (11): 349.
https://doi.org/10.1182/blood.V110.11.349.349
Published: 2007