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Journal Articles

Kinomic Profiling of Pediatric Acute Myeloid Leukemia for Detailed Cellular Insights

Hasan Mahmud, PhD, Pariya Bezrouzi, Arja ter Elst, PhD, Frank J.G. Scherpen, Kim R. Kampen, Valerie De Haas, Victor Guryev, PhD, Maikel P Peppelenbosch, Frank Johannes, PhD, Steven M. Kornblau, MD, Eveline Bont, MD PhD

Blood (2014) 124 (21): 1046.

https://doi.org/10.1182/blood.V124.21.1046.1046

Published: 2014

Journal Articles

Effect of IKZF1 Deletions on Signal Transduction Pathways in Philadelphia Chromosome-Negative B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Naomi E van der Sligte, Frank JG Scherpen, Arja ter Elst, PhD, Victor Guryev, PhD, Frank N van Leeuwen, PhD, Evelina SJM de Bont, MD PhD

Blood (2014) 124 (21): 3770.

https://doi.org/10.1182/blood.V124.21.3770.3770

Published: 2014

Journal Articles

Kinomics Profiling Of Pediatric Acute Myeloid Leukemia Based On Prognosis

Hasan Mahmud, PhD, Arja ter Elst, PhD, Frank J. G. Scherpen, T G J Meeuwsen-de Boer, Kim R. Kampen, Victor Guryev, Valerie de Haas, MD, PhD, Steven M. Kornblau, MD, Eveline S. J. M. de Bont, MD, PhD

Blood (2013) 122 (21): 1385.

https://doi.org/10.1182/blood.V122.21.1385.1385

Published: 2013

Journal Articles

Activation of the EfnB1/EphB1 Forward Signaling Promotes Cell Cycle Arrest in Acute Myeloid Leukemia Cells

Kim R Kampen, Arja ter Elst, PhD, Evelina S. De Bont, MD, PhD

Blood (2012) 120 (21): 4719.

https://doi.org/10.1182/blood.V120.21.4719.4719

Published: 2012

Journal Articles

Insights in Dynamic Kinome Reprogramming As a Consequence of MEK Inhibition in MLL-Rearranged AML.

Kim R Kampen, Arja ter Elst, PhD, Sander H Diks, PhD, Frank JG Scherpen, Valerie De Haas, Maikel P Peppelenbosch, Evelina S. De Bont, MD, PhD

Blood (2012) 120 (21): 2338.

https://doi.org/10.1182/blood.V120.21.2338.2338

Published: 2012

Journal Articles

Patterns of Bone Marrow Micro Vessel Morphology in AML and High Risk MDS Predict Treatment Outcome Following Intensive Chemotherapy and Bevacizumab

Alida C. Weidenaar, Arja ter Elst, PhD, Cees AGM van Montfort, PhD, Tiny G.J. Meeuwsen-de Boer, Stefano Rosati, MD, Mario Bargetzi, MD, Carlos Graux, MD, PhD, Alois Gratwohl, MD, PhD, Bob Lowenberg, MD, PhD, Gert Ossenkoppele, MD, PhD, Evelina S. De Bont, MD, PhD

Blood (2011) 118 (21): 1555.

https://doi.org/10.1182/blood.V118.21.1555.1555

Published: 2011

Journal Articles

EphrinB1 Activation As a Potential New Treatment Option in AML

Arja ter Elst, PhD, Kim R Kampen, Sander H Diks, PhD, Steven M. Kornblau, MD, Guillermo Garcia-Manero, Evelina S. De Bont, MD, PhD

Blood (2011) 118 (21): 5235.

https://doi.org/10.1182/blood.V118.21.5235.5235

Published: 2011

Journal Articles

Cyclic-AMP Responsive Element Binding Protein 1 (CREB) As a New Potential Druggable Target in Pediatric Acute Lymphoblastic Leukemia

Naomi E van der Sligte, Arja ter Elst, PhD, Kim R Kampen, Frank JG Scherpen, Hendrik Mulder, Sander H Diks, PhD, Frank N. van Leeuwen, PhD, Evelina S. De Bont, MD, PhD

Blood (2011) 118 (21): 1368.

https://doi.org/10.1182/blood.V118.21.1368.1368

Published: 2011

Journal Articles

Anti-VEGFC Treatment Reduces the Leukemic Outgrowth of Primary CD34+ Pediatric Acute Myeloid Leukemia Cells

Kim R Kampen, Arja ter Elst, PhD, André B Mulder, MD, Megan E Baldwin, PhD, Klupacs Robert, Evelina S.J.M. de Bont, MD, PhD

Blood (2011) 118 (21): 1425.

https://doi.org/10.1182/blood.V118.21.1425.1425

Published: 2011

Journal Articles

Epidermal Growth Factor Receptor Expression and Activity In Acute Myeloid Leukemia

Arja ter Elst, Steven M. Kornblau, MD, Frank jg Scherpen, Yi Hua Qiu, MD, Nianxiang Zhang, Kevin R Coombes, Evelina S. De Bont, MD, PhD

Blood (2010) 116 (21): 3144.

https://doi.org/10.1182/blood.V116.21.3144.3144

Published: 2010

Journal Articles

Targeting Multiple Active Kinase Pathways In 11q23 Translocated Pediatric Acute Myeloid Leukemia Using a VEGFR2 Antibody Together with a MEK Inhibitor.

Arja ter Elst, Kim R Kampen, Sander H Diks, Frank JG Scherpen, Válerie de Haas, MD, PhD, Maikel P Peppelenbosch, Evelina S. De Bont, MD, PhD

Blood (2010) 116 (21): 3626.

https://doi.org/10.1182/blood.V116.21.3626.3626

Published: 2010

Journal Articles

High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia

Hendrik J. M. de Jonge, Peter J. M. Valk, Nic J. G. M. Veeger, Arja ter Elst, Monique L. den Boer, Jacqueline Cloos, Valérie de Haas, Marry M. van den Heuvel-Eibrink, Gertjan J. L. Kaspers, Christian M. Zwaan, Willem A. Kamps, Bob Löwenberg, Eveline S. J. M. de Bont

Blood (2010) 116 (10): 1747–1754.

https://doi.org/10.1182/blood-2010-03-270991

Published: 2010

Includes: Supplemental data

Journal Articles

VEGFC Predicts Poor Outcome in Pediatric as Well as Adult Acute Myeloid Leukemia: Insights in Associated Gene Expression Profiles.

Hendrik JM de Jonge, Peter Valk, PhD, Kim R Kampen, Arja ter Elst, PhD, Gertjan Kaspers, MD, PhD, Jacqueline Cloos, PhD, C. Michel Zwaan, MD, PhD, Marry M van den Heuvel-Eibrink, MD, PhD, Willem A. Kamps, MD, PhD, Ruud Delwel, PhD, Bob Lowenberg, MD, PhD, Eveline S de Bont, MD, PhD

Blood (2009) 114 (22): 997.

https://doi.org/10.1182/blood.V114.22.997.997

Published: 2009

Journal Articles

Kinome Profiling in Acute Myeloid Leukemia as a New Approach for Target Discovery.

Arja ter Elst, Maikel P Peppelenbosch, Sander H Diks, Rob Ruijtenbeek, Piet J Boender, Rik de Wijn, Frank J.G. Scherpen, Willem A Kamps, Evelina S De Bont

Blood (2008) 112 (11): 1201.

https://doi.org/10.1182/blood.V112.11.1201.1201

Published: 2008

Journal Articles

The Role of VEGFA in Malignant Progression in AML

Alida C Weidenaar, Arja ter Elst, Henk-Marijn de Jonge, Tiny Meeuwsen-de Boer, Willem A Kamps, Evelina S De Bont

Blood (2008) 112 (11): 203.

https://doi.org/10.1182/blood.V112.11.203.203

Published: 2008

Journal Articles

Addition of PTK787/ZK 222584 Can Lower the Dosage of Amsacrine To Achieve Equal Amounts of AML Cell Death.

Alida C. Weidenaar, Hendrik J.M. de Jonge, Vaclav Fidler, PhD, Arja ter Elst, PhD, Tiny Meeuwsen, Jenny Douwes, Jessica C.A. Bouma, PhD, Karel Hählen, MD/PhD, Willem A. Kamps, MD/PhD, Evelina S. de Bont, MD/PhD

Blood (2007) 110 (11): 4199.

https://doi.org/10.1182/blood.V110.11.4199.4199

Published: 2007

Journal Articles

AML1/RUNX1, One of the Most Common Targets of Aberration in Acute Myeloid Leukemia as a Transcriptional Regulator of Vascular Endothelial Growth Factor (VEGFA).

Arja ter Elst, PhD, Bin Ma, Frank Scherpen, Bart-Jan A.T. Wierenga, Jan Jacob Schuringa, PhD, Jenny Douwes, Willem A. Kamps, MD/PhD, Evelina S. de Bont, MD/PhD

Blood (2007) 110 (11): 1618.

https://doi.org/10.1182/blood.V110.11.1618.1618

Published: 2007

Journal Articles

Endogenous VEGF-C mRNA Expression Increases In Vitro Drug Resistance of Pediatric AML Cells and Is an Independent Prognostic Factor for the Time To Reach Complete Remission in AML.

Hendrik J.M. de Jonge, Arja ter Elst, PhD, H. Marike Boezen, PhD, Alida C. Weidenaar, Frank J.G. Scherpen, Jessica C.A. Bouma-ter Steege, PhD, Gertjan J.L. Kaspers, MD/PhD, Bianca F. Goemans, MD, Ursula Creutzig, MD/PhD, Willem A. Kamps, MD/PhD, Evelina S.J.M. de Bont, MD/PhD

Blood (2006) 108 (11): 838.

https://doi.org/10.1182/blood.V108.11.838.838

Published: 2006

NARROW

Kinomic Profiling of Pediatric Acute Myeloid Leukemia for Detailed Cellular Insights

Effect of IKZF1 Deletions on Signal Transduction Pathways in Philadelphia Chromosome-Negative B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Kinomics Profiling Of Pediatric Acute Myeloid Leukemia Based On Prognosis

Activation of the EfnB1/EphB1 Forward Signaling Promotes Cell Cycle Arrest in Acute Myeloid Leukemia Cells

Insights in Dynamic Kinome Reprogramming As a Consequence of MEK Inhibition in MLL-Rearranged AML.

Patterns of Bone Marrow Micro Vessel Morphology in AML and High Risk MDS Predict Treatment Outcome Following Intensive Chemotherapy and Bevacizumab

EphrinB1 Activation As a Potential New Treatment Option in AML

Cyclic-AMP Responsive Element Binding Protein 1 (CREB) As a New Potential Druggable Target in Pediatric Acute Lymphoblastic Leukemia

Anti-VEGFC Treatment Reduces the Leukemic Outgrowth of Primary CD34+ Pediatric Acute Myeloid Leukemia Cells

Epidermal Growth Factor Receptor Expression and Activity In Acute Myeloid Leukemia

Targeting Multiple Active Kinase Pathways In 11q23 Translocated Pediatric Acute Myeloid Leukemia Using a VEGFR2 Antibody Together with a MEK Inhibitor.

High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia

VEGFC Predicts Poor Outcome in Pediatric as Well as Adult Acute Myeloid Leukemia: Insights in Associated Gene Expression Profiles.

Kinome Profiling in Acute Myeloid Leukemia as a New Approach for Target Discovery.

The Role of VEGFA in Malignant Progression in AML

Addition of PTK787/ZK 222584 Can Lower the Dosage of Amsacrine To Achieve Equal Amounts of AML Cell Death.

AML1/RUNX1, One of the Most Common Targets of Aberration in Acute Myeloid Leukemia as a Transcriptional Regulator of Vascular Endothelial Growth Factor (VEGFA).

Endogenous VEGF-C mRNA Expression Increases In Vitro Drug Resistance of Pediatric AML Cells and Is an Independent Prognostic Factor for the Time To Reach Complete Remission in AML.

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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