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Journal Articles

Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1

Leif S. Ludwig, Caleb A. Lareau, Erik L. Bao, Nan Liu, Taiju Utsugisawa, Alex M. Tseng, Samuel A. Myers, Jeffrey M. Verboon, Jacob C. Ulirsch, Wendy Luo, Christoph Muus, Claudia Fiorini, Meagan E. Olive, Christopher M. Vockley, Mathias Munschauer, Abigail Hunter, Hiromi Ogura, Toshiyuki Yamamoto, Hiroko Inada, Shinichiro Nakagawa, Shuichi Ohzono, Vidya Subramanian, Roberto Chiarle, Bertil Glader, Steven A. Carr, Martin J. Aryee, Anshul Kundaje, Stuart H. Orkin, Aviv Regev, Timothy L. McCavit, Hitoshi Kanno, Vijay G. Sankaran
Journal: Blood
Blood (2022) 139 (16): 2534–2546.
https://doi.org/10.1182/blood.2021013753
Published: 2022
Includes: Supplemental data
Journal Articles

A Genetic Disorder Reveals a Hematopoietic Stem Cell Regulatory Network Co-Opted in Leukemia

Richard Voit, Liming Tao, Fulong Yu, Blake Cohen, Liam Cato, Xiaotian Liao, Claudia Fiorini, Satish Kumar Nandakumar, Lara Wahlster, Kristian Teichert, Aviv Regev, Vijay G. Sankaran
Journal: Blood
Blood (2021) 138 (Supplement 1): 861.
https://doi.org/10.1182/blood-2021-153319
Published: 2021
Journal Articles

Single Cell Analysis Elucidates the Maturation of Human Stem and Progenitor Cell Function from Fetal through Adult Hematopoiesis

Hojun Li, Jideofor Ezike, Anton Afanassiev, Laura Greenstreet, Stephen Zhang, Jennifer S. Whangbo, Vincent Butty, Enrico Moiso, Guinevere Connelly, Vivian Morris, Dahai Wang, George Q. Daley, Salil Garg, Stella T. Chou, Aviv Regev, Edroaldo Lummertz da Rocha, Geoffrey Schiebinger, R. Grant Rowe
Journal: Blood
Blood (2021) 138 (Supplement 1): 1079.
https://doi.org/10.1182/blood-2021-151090
Published: 2021
Journal Articles

RPS15 and TP53 Co-Mutation Drives B Cell Malignancy through Altered Translation and MYC Activation in a Murine Model

Catherine Gutierrez, Tamara Ouspenskaia, PhD, Doris Fu, Peyton Waddicor, B.S., Anat Biran, PhD, Aviv Liani, Gregory Lazarian, PharmD, Elisa Ten Hacken, PhD, Elizabeth Witten, Fara Faye Regis, BS, Heather Joyal, Leah Billington, BA, Fabienne Lucas, MDPhD, Mei Zheng, Blake Tye, PhD, Maria Hernandez-Sanchez, PhD, Miguel Quijada Álamo, MSc, Shuqiang Li, PhD, Binyamin A. Knisbacher, PhD, Ziao Lin, BS, Aziz Al'Khafaji, PhD, Lili Wang, MDPhD, Kenneth J. Livak, PhD, Donna S. Neuberg, ScD, Florence Cymbalista, MD PhD, Gad Getz, PhD, Stirling Churchman, PhD, Ruben D. Carrasco, MD PhD, Sichen Shao, PhD, Aviv Regev, PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-138900
Published: 2020
Journal Articles

Hematopoietic Stem Cells Respond Heterogeneously to Inflammatory Signals in an Age-Dependent Manner

Arnav Mehta, PhD, Mati Mann, PhD, Monika Kowalczyk, PhD, Carl de Boer, PhD, Jun Wang, PhD, James Heath, PhD, Aviv Regev, PhD, David Baltimore
Journal: Blood
Blood (2016) 128 (22): 566.
https://doi.org/10.1182/blood.V128.22.566.566
Published: 2016
Journal Articles

Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL

Lili Wang, Alex K. Shalek, Mike Lawrence, Ruihua Ding, Jellert T. Gaublomme, Nathalie Pochet, Petar Stojanov, Carrie Sougnez, Sachet A. Shukla, Kristen E. Stevenson, Wandi Zhang, Jessica Wong, Quinlan L. Sievers, Bryan T. MacDonald, Alexander R. Vartanov, Natalie R. Goldstein, Donna Neuberg, Xi He, Eric Lander, Nir Hacohen, Aviv Regev, Gad Getz, Jennifer R. Brown, Hongkun Park, Catherine J. Wu
Journal: Blood
Blood (2014) 124 (7): 1089–1098.
https://doi.org/10.1182/blood-2014-01-552067
Published: 2014
Includes: Supplemental data
Journal Articles

The Transcription Factor BATF Controls CD8 + T Cell Effector Differentiation

R. Anthony Barnitz, Ph.D., Makoto Kurachi, Ph.D., Madeleine E. Lemieux, Ph.D., Nir Yosef, Ph.D., Michael A. DiIorio, Kathleen B. Yates, Jernej Godec, Pamela Odorizzi, Aviv Regev, Ph.D., E. John Wherry, Ph.D., W. Nicholas Haining, B.M., B.Ch.
Journal: Blood
Blood (2013) 122 (21): 189.
https://doi.org/10.1182/blood.V122.21.189.189
Published: 2013
Journal Articles

Risk Alleles Identified in Genome-Wide Association Studies Are Associated with Expression Quantitative Trait Loci in Chronic Lymphocytic Leukemia.

Bethany Tesar, Lillian Werner, Megan Hanna, Ma Reina Improgo, Nathalie Pochet, Stacey M. Fernandes, Laura Macconaill, Ph.D., Aviv Regev, PhD, Arnold S. Freedman, M.D., Donna S. Neuberg, ScD, Matthew L. Freedman, M.D., Jennifer R. Brown, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2875.
https://doi.org/10.1182/blood.V120.21.2875.2875
Published: 2012
Journal Articles

Novel Germline Genetic Variants Associated with Familial Chronic Lymphocytic Leukemia (CLL)

Jennifer R Brown, MD, PhD, Michael S Lawrence, Megan Hanna, Bethany Tesar, Petar Stojanov, Alexander R. Vartanov, Stacey M Fernandes, Carrie Sougnez, Laura MacConaill, Nathalie Pochet, Aviv Regev, PhD, Lillian Werner, Stacey Gabriel, Eric S Lander, Donna Neuberg, ScD, Arnold S. Freedman, MD, Gad Getz, Catherine J Wu, MD
Journal: Blood
Blood (2011) 118 (21): 465.
https://doi.org/10.1182/blood.V118.21.465.465
Published: 2011
Journal Articles

Whole Genome Sequencing Identifies Functional Mutations In the Wnt Pathway In CLL

Lili Wang, Nathalie Pochet, Kristian Cibulskis, Wandi Zhang, Mike Lawrence, Quinlan L. Sievers, Erica Shefler, Donna Neuberg, ScD, Stacey Gabriel, Carrie Sougnez, Aviv Regev, Gad Getz, Nir Hacohen, Jennifer R Brown, MD, PhD, Catherine J Wu, MD
Journal: Blood
Blood (2010) 116 (21): 693.
https://doi.org/10.1182/blood.V116.21.693.693
Published: 2010