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Journal Articles

Interplay between PI3K/mTOR Signaling and IRE1a-XBP1 Promotes Survival of Pre-B NRAS G12D all Cells Providing a Therapeutic Vulnerability for the "Undruggable" Driver RAS

Iris Appelmann, MD, Azam Salimi, Michael Huber, PhD, Mirle Schemionek, PhD, Margherita Vieri, PhD, Tim H Brümmendorf, MD, John B. Patterson, Behzad Kharabi Masouleh, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
https://doi.org/10.1182/blood-2020-140299
Published: 2020
Journal Articles

Synergistic Dual Inhibition of BCR-ABL1 and the Unfolded Protein Response Causes p38 MAPK-Mediated Cell Death and Sensitizes BCR-ABL1 + Acute Lymphoblastic Leukemia to Dexamethasone

Margherita Vieri, MSc, Christian Preisinger, Mirle Schemionek, Azam Salimi, John B. Patterson, Afshin Samali, Tim H Brümmendorf, MD, Iris Appelmann, MD, Behzad Kharabi Masouleh, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4674.
https://doi.org/10.1182/blood-2018-99-110967
Published: 2018
Journal Articles

Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

Naoya Mimura, Mariateresa Fulciniti, Gullu Gorgun, Yu-Tzu Tai, Diana Cirstea, Loredana Santo, Yiguo Hu, Claire Fabre, Jiro Minami, Hiroto Ohguchi, Tanyel Kiziltepe, Hiroshi Ikeda, Yutaka Kawano, Maureen French, Martina Blumenthal, Victor Tam, Nathalie L. Kertesz, Uriel M. Malyankar, Mark Hokenson, Tuan Pham, Qingping Zeng, John B. Patterson, Paul G. Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Blood
Blood (2012) 119 (24): 5772–5781.
https://doi.org/10.1182/blood-2011-07-366633
Published: 2012
Includes: Supplemental data
Journal Articles

Blockade of XBP1 Splicing by Inhibition of IRE1α Is a Promising Therapeutic Option in Multiple Myeloma

Naoya Mimura, MD, PhD, Mariateresa Fulciniti, PhD, Gullu Gorgun, PhD, Yu-Tzu Tai, PhD, Diana D. Cirstea, MD, Loredana Santo, MD, Yiguo Hu, PhD, Claire Fabre, MD, PhD, Jiro Minami, MD, PhD, Hiroto Ohguchi, MD, PhD, Tanyel Kiziltepe, Hiroshi Ikeda, MD, PhD, Yutaka Kawano, MD, PhD, Martina Blumenthal, Victor Tam, Nathalie L. Kertesz, Mark Hokenson, Qingping Zeng, John B. Patterson, Paul G. Richardson, MD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2011) 118 (21): 133.
https://doi.org/10.1182/blood.V118.21.133.133
Published: 2011
Journal Articles

Targeting IRE1α-XBP1 Pathway Is a Novel Therapeutic Strategy In Multiple Myeloma

Naoya Mimura, Teru Hideshima, Gullu Gorgun, Diana Cirstea, Loredana Santo, Yiguo Hu, Claire Fabre, Martina Blumenthal, Victor Tam, Nathalie L. Kertesz, Qingping Zeng, John B. Patterson, Nikhil C. Munshi, Paul Richardson, Kenneth C. Anderson
Journal: Blood
Blood (2010) 116 (21): 4074.
https://doi.org/10.1182/blood.V116.21.4074.4074
Published: 2010
Journal Articles

Shiga-Like Toxin-1 Receptor on Human Breast Cancer, Lymphoma, and Myeloma and Absence From CD34 + Hematopoietic Stem Cells: Implications for Ex Vivo Tumor Purging and Autologous Stem Cell Transplantation

E.C. LaCasse, M.R. Bray, B. Patterson, W.-M. Lim, S. Perampalam, L. G. Radvanyi, A. Keating, A.K. Stewart, R. Buckstein, J.S. Sandhu, N. Miller, D. Banerjee, D. Singh, A.R. Belch, L.M. Pilarski, J. Gariépy
Journal: Blood
Blood (1999) 94 (8): 2901–2910.
https://doi.org/10.1182/blood.V94.8.2901.420k36_2901_2910
Published: 1999
Journal Articles

Shiga-like toxin purges human lymphoma from bone marrow of severe combined immunodeficient mice

EC LaCasse, MT Saleh, B Patterson, MD Minden, J Gariepy
Journal: Blood
Blood (1996) 88 (5): 1561–1567.
https://doi.org/10.1182/blood.V88.5.1561.1561
Published: 1996
Journal Articles

Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice

J Vormoor, T Lapidot, F Pflumio, G Risdon, B Patterson, HE Broxmeyer, JE Dick
Journal: Blood
Blood (1994) 83 (9): 2489–2497.
https://doi.org/10.1182/blood.V83.9.2489.2489
Published: 1994
Journal Articles

The Effectiveness of Combinations of Antileukemic Agents in Inducing and Maintaining Remission in Children with Acute Leukemia

EMIL FREI, III, MYRON KARON, ROBERT H. LEVIN, EMIL J. FREIREICH, ROBERT J. TAYLOR, JULIET HANANIAN, OLEG SELAWRY, JAMES F. HOLLAND, BARTH HOOGSTRATEN, IRVING J. WOLMAN, ESSHAGH ABIR, ARTHUR SAWITSKY, STANLEY LEE, STEPHAN D. MILLS, E. OMER BURGERT, JR., CHARLES L. SPURR, RICHARD B. PATTERSON, FRANKLIN G. EBAUGH, G. WATSON JAMES, III, JOHN H. MOON
Journal: Blood
Blood (1965) 26 (5): 642–656.
https://doi.org/10.1182/blood.V26.5.642.642
Published: 1965