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Journal Articles

DDX41-R525H mutation promotes dysplastic hematopoiesis via aberrant splicing of key regulators of HSC biology

Free
Rasika Venkataraman, Jahan Rahman, Takero Miyagawa, Cheryl Hsueh, Axia Song, Erica Arriaga-Gomez, Fu-Yen Chang, Elizabeth Bonner, Sayantani Sinha, Ettaib El Marabti, Nifemi Akinwande, Derek Stirewalt, Anthony Rongvaux, Omar Abdel-Wahab, Sebastian Fica, Stanley Lee
Journal: Blood
Blood (2025) 146 (Supplement 1): 677.
https://doi.org/10.1182/blood-2025-677
Published: 2025
Journal Articles

The Acute Myeloid Leukemia microenvironment is defined by ineffective immune surveillance despite the presence of activated, clonally-expanded CD8 T cells with preserved effector function

Free
Y. Emily Chu, Matthew Cottam, Chad Potts, Matthew Jenkins, Justin Cartailler, Rui Lu, Stanley Lee, Robert Bowman, Robert Welner, Brent Ferrell
Journal: Blood
Blood (2025) 146 (Supplement 1): 770.
https://doi.org/10.1182/blood-2025-770
Published: 2025
Journal Articles

Impact of MDS-associated mutations and age on outcomes in NPM1-mutated AML

Free
Vivian Liu, Megan Othus, Rhonda Ries, Jasmine Naru, Era Pogosova-Agadjanyan, Frederick Appelbaum, Lan Beppu, Thomas Chauncey, Harry Erba, John Godwin, Matthew Fitzgibbon, Min Fang, Stanley Lee, Anna Moseley, Jerald Radich, Cheryl Willman, Feinan Wu, Soheil Meshinchi, Derek Stirewalt
Journal: Blood
Blood (2025) 146 (Supplement 1): 6999.
https://doi.org/10.1182/blood-2025-6999
Published: 2025
Journal Articles

The transition from myelodysplastic neoplasm to secondary acute myeloid leukemia is revealed by molecular analysis, while functional drug screening demonstrates novel sensitivity patterns with clinical implication

Free
Jieya Wu, Guangrong Qin, Brian Ball, Michelle Afkhami, Khyati Joshi, Elaine Jiang, Mika Tsubota, Yueming Tang, Tim Monahan, Lucy Ghoda, Timothy Martins, Holly Yin, Jacob Appelbaum, Stanley Lee, Sergei Doulatov, Melinda Biernacki, Derek Stirewalt, Guido Marcucci, Marie Bleakley, Pamela Becker
Journal: Blood
Blood (2025) 146 (Supplement 1): 4328.
https://doi.org/10.1182/blood-2025-4328
Published: 2025
Journal Articles

From co-occurrence to mutual exclusivity: Long read single-cell rnaseq atlas of healthy human bone marrow unveils RNA isoform landscape

Free
Elana Thieme, Erica Arriaga-Gomez, Stanley Lee, Manu Setty
Journal: Blood
Blood (2025) 146 (Supplement 1): 6133.
https://doi.org/10.1182/blood-2025-6133
Published: 2025
Journal Articles

Inhibiting the Nuclear Exporter XPO1 and the Antiapoptotic Factor BCL2 Is Synergistic in XPO1 Mutant and Wildtype Lymphoma

Free
Frank Owusu-Ansah, Jumana Afaghani, Stanley Lee, Justin Taylor, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-134807
Published: 2020
Journal Articles

ASXL2 Is a Novel Mediator of RUNX1-ETO Transcriptional Function and Collaborates with RUNX1-ETO to Promote Leukemogenesis

Free
Jean-Baptiste Micol, MD, Nicolas Duployez, Alessandro Pastore, MD, Robert Williams, Eunhee Kim, PhD, Stanley Lee, Benjamin Durham, MD PhD, Young Rock Chung, MS, Hana Cho, Claude Preudhomme, Omar Abdel-Wahab
Journal: Blood
Blood (2015) 126 (23): 302.
https://doi.org/10.1182/blood.V126.23.302.302
Published: 2015
Journal Articles

Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2

Free
Sarah A. Kinkel, Roman Galeev, Christoffer Flensburg, Andrew Keniry, Kelsey Breslin, Omer Gilan, Stanley Lee, Joy Liu, Kelan Chen, Linden J. Gearing, Darcy L. Moore, Warren S. Alexander, Mark Dawson, Ian J. Majewski, Alicia Oshlack, Jonas Larsson, Marnie E. Blewitt
Journal: Blood
Blood (2015) 125 (12): 1890–1900.
https://doi.org/10.1182/blood-2014-10-603969
Published: 2015
Includes: Supplemental data
Journal Articles

SRSF2 Mutations Impair Hematopoietic Differentiation By Altering Exonic Splicing Enhancer Preference

Free
Eunhee Kim, PhD, Janine O. Ilagan, PhD, Stanley Lee, PhD, Aravind Ramakrishnan, MD, Young Rock Chung, MS, Jean-Baptiste Micol, MD, Michele E. Murphy, Min-Kyung Kim, BS, Ahmad S. Zebari, Jacob Feala, Silvia Buonamici, PhD, Peter G Smith, PhD, H. Joachim Deeg, MD, Camille Lobry, PhD, Iannis Aifantis, PhD MSC, Robert K. Bradley, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2014) 124 (21): 824.
https://doi.org/10.1182/blood.V124.21.824.824
Published: 2014
Journal Articles

The Effectiveness of Combinations of Antileukemic Agents in Inducing and Maintaining Remission in Children with Acute Leukemia

Free
EMIL FREI, III, MYRON KARON, ROBERT H. LEVIN, EMIL J. FREIREICH, ROBERT J. TAYLOR, JULIET HANANIAN, OLEG SELAWRY, JAMES F. HOLLAND, BARTH HOOGSTRATEN, IRVING J. WOLMAN, ESSHAGH ABIR, ARTHUR SAWITSKY, STANLEY LEE, STEPHAN D. MILLS, E. OMER BURGERT, JR., CHARLES L. SPURR, RICHARD B. PATTERSON, FRANKLIN G. EBAUGH, G. WATSON JAMES, III, JOHN H. MOON
Journal: Blood
Blood (1965) 26 (5): 642–656.
https://doi.org/10.1182/blood.V26.5.642.642
Published: 1965
Journal Articles

The Effect of 6-Mercaptopurine on the Duration of Steroid-induced Remissions in Acute Leukemia: A Model for Evaluation of Other Potentially Useful Therapy

Free
ACUTE LEUKEMIA GROUP B, EMIL J FREIREICH, M.D., EDMUND GEHAN, Ph.D., EMIL FREI, III, M.D., LESLIE R. SCHROEDER, M.D., IRVING J. WOLMAN, M.D., RACHAD ANBARI, M.D., E. OMAR BURGERT, M.D., STEPHEN D. MILLS, M.D., DONALD PINKEL, M.D., OLEG S. SELAWRY, M.D., JOHN H. MOON, M.D., B. R. GENDEL, M.D., CHARLES L. SPURR, M.D., ROBERT STORRS, M.D., FARID HAURANI, M.D., BARTH HOOGSTRATEN, M.D., STANLEY LEE, M.D.
Journal: Blood
Blood (1963) 21 (6): 699–716.
https://doi.org/10.1182/blood.V21.6.699.699
Published: 1963