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Benjamin Nicholson
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Journal Articles

Type 1 Calreticulin Mutations Differentially Activate the IRE1α-XBP1 Pathway of the Unfolded Protein Response to Drive Myeloproliferative Neoplasms

Juan Ibarra, Yassmin Elbanna, Katarzyna Kurylowicz, Harrison S Greenbaum, Maria Evers, Nicole S Arellano, Dongbo Yang, Althea Bock-Hughes, Chenyu Liu, Quinn Smith, Julian Lutze, Julian Baumeister, Milena Kalmer, Kathrin Olschok, Benjamin Nicholson, Diane Silva, Luke Maxwell, Jonathan Dowgielewicz, Michele Ciboddo, Elisa Rumi, Daniela Pietra, Steffen Koschmieder, Sandeep Gurbuxani, Rebekka K. Schneider, Scott Oakes, Shannon Elf
Journal: Blood
Blood (2021) 138 (Supplement 1): 628.
https://doi.org/10.1182/blood-2021-147859
Published: 2021
Journal Articles

PRMT5 Inhibition Selectively Targets Acute Myeloid Leukemia Stem Cells Though a p53-Dependent Mechanism

Emma Toulmin, PhD, Stefan Sonderegger, PhD MSc, Loretta Cerruti, BSc, Andrej Terzic, BSc, Feng Yan, BSc, Nicholas Wong, PhD, Ian Street, PhD, Paul Stupple, PhD, Stephen Jane, MD PhD, Andrew H Wei, MBBS, PhD, Rachel Altura, PhD, Benjamin Nicholson, PhD, David J. Curtis, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4061.
https://doi.org/10.1182/blood-2018-99-117835
Published: 2018
Journal Articles

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

Stefan Sonderegger, PhD MSc, Loretta Cerruti, BSc, Cedric Tremblay, PhD, Emma Toulmin, PhD, Jesslyn Saw, BSc, Tom Nebl, PhD, Katherine M Hannan, PhD, Steven W. Lane, MD PhD, Hendrik Falk, PhD, Ashwin Unnikrishnan, PhD, Paul Stupple, PhD, Ian Street, PhD, Stephen Jane, MDPhD, Rachel Altura, PhD, Benjamin Nicholson, PhD, David J. Curtis, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 53.
https://doi.org/10.1182/blood-2018-99-118406
Published: 2018
Journal Articles

Deubiquitylating Enzyme USP-7, a Novel Therapeutic Target in Multiple Myeloma.

Dharminder Chauhan, Ph.D, Ze Tian, Ph.D, Benjamin Nicholson, Bin Zhou, Teru Hideshima, Nikhil Munshi, Paul Richardson, Kenneth C. Anderson
Journal: Blood
Blood (2009) 114 (22): 610.
https://doi.org/10.1182/blood.V114.22.610.610
Published: 2009
Journal Articles

In Vitro and In Vivo Proteasome Activity Profiles of Bortezomib and a Novel Proteasome Inhibitor NPI-0052.

Dharminder Chauhan, PhD, Ta-Hsiang Chao, Ph.D, Laurence Catley, M.D, Benjamin Nicholson, Ph.D, Mugdha Velanker, M.S, Teru Hideshima, Ph.D, Celia Berkers, Ph.D, Huib Ovaa, Ph.D, Saskia Neuteboom, Ph.D, Michael Palladino, Ph.D, Kenneth C. Anderson, M.D
Journal: Blood
Blood (2005) 106 (11): 3363.
https://doi.org/10.1182/blood.V106.11.3363.3363
Published: 2005