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Journal Articles

Zalypsis Has Synergistic Effect When Combined with Bortezomib + Dexamethasone through Caspase Dependent and Mainly Independent Mechanisms and through A Potent Induction of DNA Damage

Enrique M. Ocio, Lorena González-Coco, Laura San-Segundo, Xi Chen, Teresa Hernández-Iglesias, Diego Fernández-Lázaro, Teresa Paíno, Mercedes Garayoa, Carmen Cuevas, Pablo Avilés, Enrique Álava, Atanasio Pandiella, J.F San Miguel
Journal: Blood
Blood (2010) 116 (21): 3003.
https://doi.org/10.1182/blood.V116.21.3003.3003
Published: 2010
Journal Articles

Zalypsis Possess Potent Antileukemic Effect through the Induction of a DNA Damage Response, Independently of the p53 Status.

Enrique Colado, Teresa Paíno, Enrique M Ocio, Patricia Maiso, Xi Chen, Stela Álvarez-Fernández, Jesús Martín-Sánchez, Lorena González, Laura San-Segundo, Mercedes Garayoa, Diego Fernández-Lázaro, Maria-Belén Vidriales, Carlos Galmarini, Pablo Avilés, Carmen Cuevas, Atanasio Pandiella, Jesús F. San-Miguel, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3792.
https://doi.org/10.1182/blood.V114.22.3792.3792
Published: 2009
Journal Articles

Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks

Enrique M. Ocio, Patricia Maiso, Xi Chen, Mercedes Garayoa, Stela Álvarez-Fernández, Laura San-Segundo, David Vilanova, Lucía López-Corral, Juan C. Montero, Teresa Hernández-Iglesias, Enrique de Álava, Carlos Galmarini, Pablo Avilés, Carmen Cuevas, Jesús F. San-Miguel, Atanasio Pandiella
Journal: Blood
Blood (2009) 113 (16): 3781–3791.
https://doi.org/10.1182/blood-2008-09-177774
Published: 2009
Includes: Supplemental data
Journal Articles

DNA Double Strand Breaks Induction by Zalypsis, a Novel Marine Compound, Results in Potent Antimyeloma Activity

Enrique M Ocio, Patricia Maiso, Xi Chen, Mercedes Garayoa, Stela Álvarez-Fernández, Laura San-Segundo, David Vilanova, Lucía López-Corral, Juan Carlos Montero, Teresa Hernández-Iglesias, Enrique de Álava, Carlos Galmarini, Pablo Avilés, Carmen Cuevas, Atanasio Pandiella, J.F. San Miguel, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 245.
https://doi.org/10.1182/blood.V112.11.245.245
Published: 2008
Journal Articles

Antimyeloma Efficacy of Plitidepsin (Aplidin®): From Bench to the Bedside.

Enrique M. Ocio, Constantine Mitsiades, M. Victoria Mateos, Patricia Maiso, Faustino Mollinedo, Mercedes Garayoa, Consuelo Gajate, Joan Blade, Felipe Prosper, Juan José Lahuerta, Nicholas Mitsiades, Ciaran J. McMullan, Nikhil C. Munshi, Teru Hideshima, Dharminder Chauhan, Carmen Cuevas, Pablo Avilés, Glynn Faircloth, Paul G. Richardson, Atanasio Pandiella, Kenneth C. Anderson, J.F. San Miguel
Journal: Blood
Blood (2007) 110 (11): 1178.
https://doi.org/10.1182/blood.V110.11.1178.1178
Published: 2007