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Chenwei Tian
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Journal Articles

Safety and efficacy of the mutant calreticulin-specific monoclonal antibody INCA033989 as monotherapy or in combination with ruxolitinib in patients (pts) with myelofibrosis (MF): Preliminary results from dose escalation of two global Phase 1 studies

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John Mascarenhas, Haifa Kathrin Al-Ali, Vikas Gupta, Haris Ali, Francesca Palandri, Professor Francesco Passamonti, Raajit Rampal, Aaron Gerds, Tania Jain, Sanjay Mohan, Steffen Koschmieder, Caroline McNamara, Andrew Perkins, Bethan Psaila, Vincent Ribrag, William Shomali, Rosa Ayala Diaz, Mikkel Helleberg Dorff, Claire Harrison, Stephen Oh, Frank Stegelmann, Alessandro Maria Vannucchi, Abdulraheem Yacoub, Jason Gotlib, Jyoti Nangalia, Chenwei Tian, Betty Lamothe, Erin Crowgey, Tatiana Zinger, Evan Braunstein, David Ross
Journal: Blood
Blood (2025) 146 (Supplement 1): 484.
https://doi.org/10.1182/blood-2025-484
Published: 2025
Journal Articles

Safety and efficacy of INCA033989, a novel first in class mutant calreticulin-specific monoclonal antibody, in patients with essential thrombocythemia

Free
Vikas Gupta, John Mascarenhas, Haris Ali, David Ross, Abdulraheem Yacoub, Tania Jain, Lynette Chee, Aaron Gerds, Jean-Jacques Kiladjian, Ruben Mesa, William Shomali, Makoto Yoshimitsu, Rosa Ayala Diaz, Chi-Joan How, Steffen Koschmieder, Caroline McNamara, Yosuke Nakaya, Francesca Palandri, Professor Francesco Passamonti, Andrew Perkins, Bethan Psaila, Raajit Rampal, Natasha Szuber, Frank Stegelmann, Alessandro Maria Vannucchi, Hiroki Yamaguchi, Jason Gotlib, Jyoti Nangalia, Chenwei Tian, Betty Lamothe, Erin Crowgey, Tatiana Zinger, Evan Braunstein, Claire Harrison
Journal: Blood
Blood (2025) 146 (Supplement 1): 1024.
https://doi.org/10.1182/blood-2025-1024
Published: 2025
Journal Articles

Molecular characterization of patients (pts) with myeloproliferative neoplasms treated with INCA033989 demonstrates selective targeting of CALR mutant hematopoietic cells

Free
Bethan Psaila, Jyoti Nangalia, Jason Gotlib, Claire Harrison, John Mascarenhas, Erin Crowgey, Betty Lamothe, Chenwei Tian, Evan Braunstein, Steffen Koschmieder
Journal: Blood
Blood (2025) 146 (Supplement 1): 71.
https://doi.org/10.1182/blood-2025-71
Published: 2025