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Journal Articles

A Crucial Role for Caspase 1 in Thrombo-Inflammatory Microparticle Release

Andrea S Rothmeier, PhD, Patrizia Marchese, PhD, Christian Furlan-Freguia, PhD, Brian G. Petrich, PhD, Mark H. Ginsberg, MD, Zaverio M Ruggeri, MD, Wolfram Ruf, MD

Blood (2014) 124 (21): 2806.

https://doi.org/10.1182/blood.V124.21.2806.2806

Published: 2014

Journal Articles

Thrombosis and Inflammation Are Coupled by a Common Thioredoxin Reductase Pathway Downstream of the P2×7 Receptor.

Andrea S Rothmeier, Ph.D., Christian Furlan-Freguia, Ph.D., Brian G. Petrich, PhD, Patrizia Marchese, PhD, Zaverio M. Ruggeri, MD, PhD, Mark H. Ginsberg, M.D., Wolfram Ruf, MD

Blood (2012) 120 (21): 2218.

https://doi.org/10.1182/blood.V120.21.2218.2218

Published: 2012

Journal Articles

Inflammation, Obesity, and Thrombosis

Fahumiya Samad, PhD, Leylla Badeanlou, Christian Furlan-Freguia, PhD, Guang Yang, PhD, Wolfram Ruf, MD

Blood (2012) 120 (21): SCI-45.

https://doi.org/10.1182/blood.V120.21.SCI-45.SCI-45

Published: 2012

Journal Articles

Protease-Activated Receptor 4 (PAR4) Plays a Critical Role in Fetal Loss and Peripheral Thrombosis in a Mouse Model of Thrombophilia

Joshua Siner, Christian Furlan Freguia, Michael Maiden, Jianhua Liu, Stefano Baila, Valder Arruda, MD, PhD

Blood (2011) 118 (21): 373.

https://doi.org/10.1182/blood.V118.21.373.373

Published: 2011

Journal Articles

P2×7 Signaling Triggers Tissue Factor Activation and Protein Disulfide Isomerase-Dependent Release of TF + Microparticles In Thrombosis

Christian Furlan Freguia, Patrizia Marchese, Andras Gruber, Zaverio M. Ruggeri, MD, Wolfram Ruf, MD

Blood (2010) 116 (21): 344.

https://doi.org/10.1182/blood.V116.21.344.344

Published: 2010

Journal Articles

Novel Infrared Fluorescence Methodology Defines An Essential Role for Endothelial Protein C Receptor (EPCR) for Protection Against Vascular Leakage In Inflammation

Annette Von Drygalski, MD, PharmD, Christian Furlan-Freguia, PhD, Laurent O. Mosnier, PhD, Wolfram Ruf, MD, John H. Griffin, PhD

Blood (2010) 116 (21): 653.

https://doi.org/10.1182/blood.V116.21.653.653

Published: 2010

Journal Articles

Recombinant canine B-domain–deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model

Denise E. Sabatino, Christian Furlan Freguia, Raffaella Toso, Andrey Santos, Elizabeth P. Merricks, Haig H. Kazazian, Jr, Timothy C. Nichols, Rodney M. Camire, Valder R. Arruda

Blood (2009) 114 (20): 4562–4565.

https://doi.org/10.1182/blood-2009-05-220327

Published: 2009

Includes: Supplemental data

Journal Articles

Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality

Frank Niessen, Christian Furlan-Freguia, José A. Fernández, Laurent O. Mosnier, Francis J. Castellino, Hartmut Weiler, Hugh Rosen, John H. Griffin, Wolfram Ruf

Blood (2009) 113 (12): 2859–2866.

https://doi.org/10.1182/blood-2008-12-192385

Published: 2009

Journal Articles

Successful Production of Canine FVIII: Biochemical and Functional Characterization in Hemophilia A Dogs.

Christian Furlan Freguia, PhD, Denise E. Sabatino, PhD, Andrey Santos, BS, Amy Lange, BS, Raffaella Toso, PhD, Timothy C. Nichols, MD, Rodney M. Camire, PhD, Valder R. Arruda, MD, PhD

Blood (2007) 110 (11): 495.

https://doi.org/10.1182/blood.V110.11.495.495

Published: 2007

Journal Articles

Protease−Activated Receptor 2 (PAR−2) as a Novel Target To Prevent Inhibitor Formation to FIX.

Stefano Baila, Christian Furlan Freguia, Nicholas Iacobelli, Danielle Dunn, Joerg Schuettrumpf, Federico Mingozzi, Patricia Andrade-Gordon, Valder R. Arruda

Blood (2006) 108 (11): 763.

https://doi.org/10.1182/blood.V108.11.763.763

Published: 2006

Journal Articles

Differences in the Anticoagulant Activity of Murine and Human Activated Protein C (APC) in Mouse Thrombosis Models.

Christian Furlan Freguia, Joerg Schuettrumpf, Stefano Baila, Alexander Schlachterman, Jianxang Zou, Shangzhen Zhou, Valder R. Arruda

Blood (2006) 108 (11): 1471.

https://doi.org/10.1182/blood.V108.11.1471.1471

Published: 2006

Journal Articles

Assessing the Role of Continuous Activated Protein C (APC) Expression in Murine Thrombosis Models.

Joerg Schuettrumpf, MD, Alexander Schlachterman, Jianxiang Zou, PhD, Christian Furlan Freguia, Stefano Baila, Valder R. Arruda, MD

Blood (2005) 106 (11): 1030.

https://doi.org/10.1182/blood.V106.11.1030.1030

Published: 2005

Journal Articles

Protease-Activated Receptor-2 (PAR-2) as a Novel Target for Modulating Immune Responses to Neo Antigens Following In Vivo Gene Transfer.

Stefano Baila, Christian Furlan Freguia, Daniel Orr, Federico Mingozzi, Joerge Schuettrumpf, Valder R. Arruda

Blood (2005) 106 (11): 1296.

https://doi.org/10.1182/blood.V106.11.1296.1296

Published: 2005

Journal Articles

Co-Inheritance of FV Leiden and High Levels of FIX Results in Novel Models for Thrombophilia and Spontaneous Fetal Loss.

Christian Furlan Freguia, Joerg Schuettrumpf, Stefano Baila, Jianhua Liu, Ralph Bunte, Rodney M. Camire, Valder R. Arruda

Blood (2005) 106 (11): 1946.

https://doi.org/10.1182/blood.V106.11.1946.1946

Published: 2005

Journal Articles

Expression of Blood Coagulation Factor X Is Not Liver-Restricted.

Shing Jen Tai, BA, Parker Hudson, BS, Christian Furlan Freguia, MS, Katherine A. High, MD

Blood (2004) 104 (11): 1939.

https://doi.org/10.1182/blood.V104.11.1939.1939

Published: 2004

NARROW

A Crucial Role for Caspase 1 in Thrombo-Inflammatory Microparticle Release

Thrombosis and Inflammation Are Coupled by a Common Thioredoxin Reductase Pathway Downstream of the P2×7 Receptor.

Inflammation, Obesity, and Thrombosis

Protease-Activated Receptor 4 (PAR4) Plays a Critical Role in Fetal Loss and Peripheral Thrombosis in a Mouse Model of Thrombophilia

P2×7 Signaling Triggers Tissue Factor Activation and Protein Disulfide Isomerase-Dependent Release of TF + Microparticles In Thrombosis

Novel Infrared Fluorescence Methodology Defines An Essential Role for Endothelial Protein C Receptor (EPCR) for Protection Against Vascular Leakage In Inflammation

Recombinant canine B-domain–deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model

Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality

Successful Production of Canine FVIII: Biochemical and Functional Characterization in Hemophilia A Dogs.

Protease−Activated Receptor 2 (PAR−2) as a Novel Target To Prevent Inhibitor Formation to FIX.

Differences in the Anticoagulant Activity of Murine and Human Activated Protein C (APC) in Mouse Thrombosis Models.

Assessing the Role of Continuous Activated Protein C (APC) Expression in Murine Thrombosis Models.

Protease-Activated Receptor-2 (PAR-2) as a Novel Target for Modulating Immune Responses to Neo Antigens Following In Vivo Gene Transfer.

Co-Inheritance of FV Leiden and High Levels of FIX Results in Novel Models for Thrombophilia and Spontaneous Fetal Loss.

Expression of Blood Coagulation Factor X Is Not Liver-Restricted.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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