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Christopher D. Chien
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Journal Articles

CD19/22 CAR T cells in children and young adults with B-ALL: phase 1 results and development of a novel bicistronic CAR

Clinical Trials & Observations
Haneen Shalabi, Haiying Qin, Angela Su, Bonnie Yates, Pamela L. Wolters, Seth M. Steinberg, John A. Ligon, Sara Silbert, Kniya DéDé, Mehdi Benzaoui, Sophia Goldberg, Sooraj Achar, Dina Schneider, Shilpa A. Shahani, Lauren Little, Toni Foley, John C. Molina, Sandhya Panch, Crystal L. Mackall, Daniel W. Lee, Christopher D. Chien, Marie Pouzolles, Mark Ahlman, Constance M. Yuan, Hao-Wei Wang, Yanyu Wang, Jon Inglefield, Mary Anne Toledo-Tamula, Staci Martin, Steven L. Highfill, Gregoire Altan-Bonnet, David Stroncek, Terry J. Fry, Naomi Taylor, Nirali N. Shah
Journal: Blood
Blood (2022) 140 (5): 451–463.
https://doi.org/10.1182/blood.2022015795
Published: 2022
Includes: Supplemental data
Journal Articles

Murine allogeneic CD19 CAR T cells harbor potent antileukemic activity but have the potential to mediate lethal GVHD

Elad Jacoby, Yinmeng Yang, Haiying Qin, Christopher D. Chien, James N. Kochenderfer, Terry J. Fry
Journal: Blood
Blood (2016) 127 (10): 1361–1370.
https://doi.org/10.1182/blood-2015-08-664250
Published: 2016
Includes: Supplemental data
Journal Articles

Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD

Christian M. Capitini, Nicole M. Nasholm, Christopher D. Chien, Shannon M. Larabee, Haiying Qin, Young K. Song, Peter J. Klover, Lothar Hennighausen, Javed Khan, Terry J. Fry
Journal: Blood
Blood (2014) 124 (12): 1976–1986.
https://doi.org/10.1182/blood-2013-05-500876
Published: 2014
Includes: Supplemental data
Journal Articles

Thymic Stromal Lymphopoeitin Signaling Contributes To Increased Risk Of Relapse Of Pediatric Acute Lympoblastic Leukemia Through Enhanced Survival Of Leukemic Cells That Overexpress Thymic Stromal Lymphopoeitin Receptor

Christopher D Chien, PhD, Matthew Kreitman, Haiying Qin, MS, Terry J Fry, MD
Journal: Blood
Blood (2013) 122 (21): 2543.
https://doi.org/10.1182/blood.V122.21.2543.2543
Published: 2013
Journal Articles

Precursor B Cell Acute Lymphoblastic Leukemia Induces Pro-Leukemic Changes in the Bone Marrow Microenvironment That Contribute to Therapeutic Resistance

Christopher D Chien, PhD, Elizabeth D Hicks, Paul P Su, Haiying Qin, MS, Terry J Fry, MD
Journal: Blood
Blood (2012) 120 (21): 1466.
https://doi.org/10.1182/blood.V120.21.1466.1466
Published: 2012
Journal Articles

Vaccination regimens incorporating CpG-containing oligodeoxynucleotides and IL-2 generate antigen-specific antitumor immunity from T-cell populations undergoing homeostatic peripheral expansion after BMT

James N. Kochenderfer, Jessica L. Simpson, Christopher D. Chien, Ronald E. Gress
Journal: Blood
Blood (2007) 110 (1): 450–460.
https://doi.org/10.1182/blood-2006-11-057935
Published: 2007