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Journal Articles

EGR1-mediated metabolic reprogramming to oxidative phosphorylation contributes to ibrutinib resistance in B-cell lymphoma

Yunxia Liu, Shuichi Kimpara, Nguyet M. Hoang, Anusara Daenthanasanmak, Yangguang Li, Li Lu, Vu N. Ngo, Paul D. Bates, Longzhen Song, Xiaoyue Gao, Samantha Bebel, Madelyn Chen, Ruoyu Chen, Xiyu Zhang, Paul E. Selberg, Vaishalee P. Kenkre, Thomas A. Waldmann, Christian M. Capitini, Lixin Rui

Blood (2023) 142 (22): 1879–1894.

https://doi.org/10.1182/blood.2023020142

Published: 2023

Includes: Supplemental data

Journal Articles

Fedratinib and Venetoclax Have Synergistic Activity Against B-Cell Acute Lymphoblastic Leukemia in Vitro

Sean P Rinella, Haley C Bell, Lei Shi, Lixin Rui, Christian M. Capitini

Blood (2021) 138 (Supplement 1): 1241.

https://doi.org/10.1182/blood-2021-152909

Published: 2021

Journal Articles

Differentiation of a CD4/CD8αβ Double Positive T Cell Population from the CD8 Pool Is Both Predictive and Sufficient to Mediate Graft-Vs-Host Disease

Nicholas J. Hess, David Turicek, Amy Hudson, Peiman Hematti, Jenny Gumperz, Christian M. Capitini

Blood (2021) 138 (Supplement 1): 2761.

https://doi.org/10.1182/blood-2021-147304

Published: 2021

Journal Articles

Versican Proteolytic Fragments (Matrikines) Regulate the Intratumoral Dendritic Cell Milieu In Vivo: Implications for in Situ Tumor Vaccination

Athanasios Papadas, MD, Evan Flietner, BS, Zachary Morrow, BS, Joshua Wiesner, Alexander Cicala, Adam Pagenkopf, BS, Chelsea L. Hope, PhD, Adhithi Rajagopalan, BS, Zhi Wen, PhD, Philip Emmerich, Dustin Deming, Shigeki Miyamoto, PhD, Peiman Hematti, MD, Natalie Scott Callander, MD, Alexander Rakhmilevich, Mario Otto, MD PhD, Christian M. Capitini, MD, Jing Zhang, PhD, Fotis Asimakopoulos, PhDMBBChir,

Blood (2019) 134 (Supplement_1): 1210.

https://doi.org/10.1182/blood-2019-131582

Published: 2019

Journal Articles

Efficacy and Safety of CTL019 in the First US Phase II Multicenter Trial in Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia: Results of an Interim Analysis

Shannon L Maude, MD PhD, Michael A Pulsipher, MD, Michael W Boyer, MD, Stephan A Grupp, MD PhD, Stella M Davies, MBBS, PhD, Christine L Phillips, MD, Michael R Verneris, MD, Keith J August, MD MS, Krysta Schlis, MD, Timothy A Driscoll, MD, Rajen Mody, MD MS, Christian M Capitini, MD, Carl H June, MD, Bruce L Levine, PhD, Patricia A Wood, MD PhD, Lan Yi, PhD, John E Levine, MD MS

Blood (2016) 128 (22): 2801.

https://doi.org/10.1182/blood.V128.22.2801.2801

Published: 2016

Journal Articles

Synergistic Co-Targeting of BTK and BCL2 in Mantle Cell Lymphoma

Yangguang Li, PhD, Myriam N. Bouchlaka, BS, PhD, Kreg Grindle, Brad S Kahl, MD, Shigeki Miyamoto, David T Yang, MD, Christian M. Capitini, MD, Lixin Rui, PhD

Blood (2015) 126 (23): 708.

https://doi.org/10.1182/blood.V126.23.708.708

Published: 2015

Journal Articles

Inhibition of the JAK/STAT and Bcl-2 Pathways Enhances Anti-Tumor Effects in an in Vitro model of T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Tara Bree Gavcovich, BS, Kirsti Lorraine Walker, BS,MS, Myriam N. Bouchlaka, BS, PhD, Christian M Capitini, MD

Blood (2015) 126 (23): 2528.

https://doi.org/10.1182/blood.V126.23.2528.2528

Published: 2015

Journal Articles

Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD

Christian M. Capitini, Nicole M. Nasholm, Christopher D. Chien, Shannon M. Larabee, Haiying Qin, Young K. Song, Peter J. Klover, Lothar Hennighausen, Javed Khan, Terry J. Fry

Blood (2014) 124 (12): 1976–1986.

https://doi.org/10.1182/blood-2013-05-500876

Published: 2014

Includes: Supplemental data

Journal Articles

Tissue Distribution of a Minor Antigen, but Not PD-1 Expression, Predicts the Antileukemia Efficacy of Adoptively Transferred, Antigen-Specific T-Cells in a Preclinical Model of Allogeneic Transplant

Jessica C. Shand, MD, Christian M. Capitini, MD, Haiying Qin, MS, Nicole Nasholm, BS, Terry J. Fry, MD

Blood (2012) 120 (21): 456.

https://doi.org/10.1182/blood.V120.21.456.456

Published: 2012

Journal Articles

Alloreactivity Directed Against the Widely Distributed HY Antigen Impairs Antitumor Immunity and Results in T-Cell Dysfunction

Jessica C Shand, MD, Christian M. Capitini, MD, Haiying Qin, M.S., Nicole Nasholm, BA, Brynn B Duncan, BS, Terry J Fry, MD

Blood (2011) 118 (21): 2964.

https://doi.org/10.1182/blood.V118.21.2964.2964

Published: 2011

Journal Articles

Gvhd Increases Apoptosis of CD8 + , but Not CD4 + , T Cells Expanded by Vaccines but Is Not Dependent on Fas Ligand

Christian M. Capitini, MD, Martin Guimond, PhD, Terry J Fry, MD

Blood (2010) 116 (21): 2098.

https://doi.org/10.1182/blood.V116.21.2098.2098

Published: 2010

Journal Articles

4-1BBL-Expressing aAPCs Attenuate IL-15-Induced NK Cell Expansion and Cytokine Production In Vitro but Induce NK Cell-Mediated Gvhd In Vivo

Christian M. Capitini, MD, Joanna L. Meadors, BS, Monica M. Cho, Rimas J. Orentas, PhD, Crystal L. Mackall, MD, Terry J. Fry, MD

Blood (2010) 116 (21): 2536.

https://doi.org/10.1182/blood.V116.21.2536.2536

Published: 2010

Journal Articles

Adoptive Transfer of Primed T Cells Mediates a Graft-Versus-Leukemia Effect against Pediatric ALL.

Haiying Qin, M.S., Jessica PE Davis, B.A., Christian M. Capitini, MD, Terry J Fry, MD

Blood (2009) 114 (22): 1340.

https://doi.org/10.1182/blood.V114.22.1340.1340

Published: 2009

Journal Articles

Bone marrow deficient in IFN-γ signaling selectively reverses GVHD-associated immunosuppression and enhances a tumor-specific GVT effect

Christian M. Capitini, Sarah Herby, Matthew Milliron, Miriam R. Anver, Crystal L. Mackall, Terry J. Fry

Blood (2009) 113 (20): 5002–5009.

https://doi.org/10.1182/blood-2008-11-187385

Published: 2009

Includes: Supplemental data

Journal Articles

Disruption of Gamma Interferon Signaling through the STAT1 Pathway Enhances Alloreactivity While Abrogating GvHD

Christian M. Capitini, M.D., Shannon M. Larabee, B.A., Crystal L. Mackall, M.D., Terry J. Fry, M.D.

Blood (2008) 112 (11): 3512.

https://doi.org/10.1182/blood.V112.11.3512.3512

Published: 2008

Journal Articles

GVHD Abrogates T Cell Responses to Dendritic Cell Vaccines but Not Vaccine-Induced Proliferation.

Christian M. Capitini, MD, Martin Guimond, PhD, Crystal L. Mackall, MD, Terry J. Fry, MD

Blood (2007) 110 (11): 1802.

https://doi.org/10.1182/blood.V110.11.1802.1802

Published: 2007

Journal Articles

Extracorporeal Photopheresis Diminishes Graft-Versus-Host-Disease and Modulates Dendritic Cell Cytokine Production.

Jessica P. Davis, Sarah Herby, Meghaan P. Walsh, Christian M. Capitini, M.D., Martin Guimond, Ph.D., Alan Wayne, M.D., Terry J. Fry, M.D.

Blood (2007) 110 (11): 2177.

https://doi.org/10.1182/blood.V110.11.2177.2177

Published: 2007

Journal Articles

Loss of IFNγR1 Signaling on Donor Bone Marrow Abrogates GVHD but Maintains Immunocompetence.

Christian M. Capitini, MD, Sarah Herby, BS, Crystal L. Mackall, MD, Terry J. Fry, MD

Blood (2007) 110 (11): 2180.

https://doi.org/10.1182/blood.V110.11.2180.2180

Published: 2007

Journal Articles

Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo

Crystal Y. Koh, Bruce R. Blazar, Thaddeus George, Lisbeth A. Welniak, Christian M. Capitini, Arati Raziuddin, William J. Murphy, Michael Bennett

Blood (2001) 97 (10): 3132–3137.

https://doi.org/10.1182/blood.V97.10.3132

Published: 2001

NARROW

EGR1-mediated metabolic reprogramming to oxidative phosphorylation contributes to ibrutinib resistance in B-cell lymphoma

Fedratinib and Venetoclax Have Synergistic Activity Against B-Cell Acute Lymphoblastic Leukemia in Vitro

Differentiation of a CD4/CD8αβ Double Positive T Cell Population from the CD8 Pool Is Both Predictive and Sufficient to Mediate Graft-Vs-Host Disease

Versican Proteolytic Fragments (Matrikines) Regulate the Intratumoral Dendritic Cell Milieu In Vivo: Implications for in Situ Tumor Vaccination

Efficacy and Safety of CTL019 in the First US Phase II Multicenter Trial in Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia: Results of an Interim Analysis

Synergistic Co-Targeting of BTK and BCL2 in Mantle Cell Lymphoma

Inhibition of the JAK/STAT and Bcl-2 Pathways Enhances Anti-Tumor Effects in an in Vitro model of T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD

Tissue Distribution of a Minor Antigen, but Not PD-1 Expression, Predicts the Antileukemia Efficacy of Adoptively Transferred, Antigen-Specific T-Cells in a Preclinical Model of Allogeneic Transplant

Alloreactivity Directed Against the Widely Distributed HY Antigen Impairs Antitumor Immunity and Results in T-Cell Dysfunction

Gvhd Increases Apoptosis of CD8 + , but Not CD4 + , T Cells Expanded by Vaccines but Is Not Dependent on Fas Ligand

4-1BBL-Expressing aAPCs Attenuate IL-15-Induced NK Cell Expansion and Cytokine Production In Vitro but Induce NK Cell-Mediated Gvhd In Vivo

Adoptive Transfer of Primed T Cells Mediates a Graft-Versus-Leukemia Effect against Pediatric ALL.

Bone marrow deficient in IFN-γ signaling selectively reverses GVHD-associated immunosuppression and enhances a tumor-specific GVT effect

Disruption of Gamma Interferon Signaling through the STAT1 Pathway Enhances Alloreactivity While Abrogating GvHD

GVHD Abrogates T Cell Responses to Dendritic Cell Vaccines but Not Vaccine-Induced Proliferation.

Extracorporeal Photopheresis Diminishes Graft-Versus-Host-Disease and Modulates Dendritic Cell Cytokine Production.

Loss of IFNγR1 Signaling on Donor Bone Marrow Abrogates GVHD but Maintains Immunocompetence.

Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo

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American Society of Hematology

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American Society of Hematology

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