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Christopher Patriquin
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Journal Articles

Maternal and fetal pharmacokinetics (PK) of pegcetacoplan in paroxysmal nocturnal hemoglobinuria (PNH): A case report of use in pregnancy

Free
Benjamin Chin-Yee, Benjamin Hedley, Rui Su, Barbra De Vrijer, Facundo Garcia-Bournissen, Sarah Parkinson, Cyrus Hsia, Matthew Nichols, Ian Chin-Yee, Christopher Patriquin
Journal: Blood
Blood (2025) 146 (Supplement 1): 3199.
https://doi.org/10.1182/blood-2025-3199
Published: 2025
Journal Articles

Efficacy and safety of pozelimab plus cemdisiran versus ravulizumab in patients with paroxysmal nocturnal hemoglobinuria who received prior C5 therapy

Free
Jun Ho Jang, Christopher Patriquin, Deepak Taneja, Zhentao Tong, Elham Shirvani Dastgerdi, Amal Souttou, Lorah Perlee, Morag Griffin
Journal: Blood
Blood (2025) 146 (Supplement 1): 1420.
https://doi.org/10.1182/blood-2025-1420
Published: 2025
Journal Articles

Switching between complement inhibitors in patients with PNH: A real-world analysis of strategy, efficacy, and safety.

Free
Morag Griffin, Bruno Fattizzo, Jong Wook Lee, Richard Kelly, Roochi Trikha, Yasutaka Ueda, Jun-ichi Nishimura, Christopher Patriquin, Alexander Röth, Petra Muus, Jens Panse, Miguel Gómez Álvarez, Alexandra Pike, Talha Munir, Shreyans Gandhi, Austin Kulasekararaj
Journal: Blood
Blood (2025) 146 (Supplement 1): 1114.
https://doi.org/10.1182/blood-2025-1114
Published: 2025
Journal Articles

Danicopan add-on therapy demonstrates positive efficacy and safety outcomes in advanced age adults with paroxysmal nocturnal hemoglobinuria and clinically significant extravascular hemolysis: A sub-analysis of the phase 3 ALPHA trial

Free
Austin Kulasekararaj, Morag Griffin, Robert Brodsky, Jun-ichi Nishimura, Christopher Patriquin, Hubert Schrezenmeier, Wilma Barcellini, Anna Gaya, Yogesh Patel, Ying Tang, Gleb Filippov, Mohammed Mahdi, Flore Sicre-de-Fontbrune, Jong Wook Lee
Journal: Blood
Blood (2025) 146 (Supplement 1): 949.
https://doi.org/10.1182/blood-2025-949
Published: 2025
Journal Articles

Long-term efficacy and safety of danicopan as add-on therapy to ravulizumab or eculizumab in PNH with significant EVH

Open Access
Clinical Trials & Observations
Austin Kulasekararaj, Morag Griffin, Caroline Piatek, Jamile Shammo, Jun-ichi Nishimura, Christopher Patriquin, Hubert Schrezenmeier, Wilma Barcellini, Jens Panse, Anna Gaya, Yogesh Patel, Peng Liu, Gleb Filippov, Flore Sicre de Fontbrune, Antonio Risitano, Jong Wook Lee
Journal: Blood
Blood (2025) 145 (8): 811–822.
https://doi.org/10.1182/blood.2024026299
Published: 2025
Includes: Supplemental data
Journal Articles

Efficacy and Safety of Pozelimab Plus Cemdisiran Vs Ravulizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria Who Are Naïve to Complement Inhibition

Free
Christopher Patriquin, Jun-Ho Jang, Lisa Aurand, Deepak Taneja, Andrew Magyar, Bradley Dain, Karoline Meagher, Lorah Perlee, Amal Souttou, Morag Griffin
Journal: Blood
Blood (2024) 144 (Supplement 1): 306.
https://doi.org/10.1182/blood-2024-194610
Published: 2024
Journal Articles

Routine Pre-Apheresis Markers As Predictors for Efficacy and Safety Outcomes Following CD19 CAR-T Cell Therapy - a Single Center Experience

Free
Melissa Teixeira Maltez, Katrina Hueniken, Rachel Aitken, Carmel Waldron, Michael Crump, John Kuruvilla, Anca Prica, Vishal Kukreti, Robert Kridel, Abi Vijenthira, Chloe Yang, Christine I Chen, Richard Tsang, David Hodgson, Danielle Rodin, Nauman Malik, Woodrow Wells, David Barth, Christopher Patriquin, Sita D. Bhella
Journal: Blood
Blood (2024) 144 (Supplement 1): 6548.
https://doi.org/10.1182/blood-2024-205736
Published: 2024
Journal Articles

Danicopan As Add-on Therapy to Ravulizumab or Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria: Long-Term Patient-Reported Outcomes from the Phase 3 ALPHA Trial

Free
Caroline Piatek, Jong Wook Lee, Morag Griffin, Jun-Ichi Nishimura, Christopher Patriquin, Hubert Schrezenmeier, Wilma Barcellini, Jamile Shammo, Anna Gaya, Mohammed Mahdi, Peng Liu, Karl-Johan Myren, Andrew Messali, Flore Sicre de Fontbrune, Jens Panse, Austin G. Kulasekararaj
Journal: Blood
Blood (2024) 144 (Supplement 1): 2692.
https://doi.org/10.1182/blood-2024-199506
Published: 2024
Journal Articles

Evaluating Neuroprotective Effects of Caplacizumab in Immune-Mediated Thrombotic Thrombocytopenic Purpura

Free
Fahad Hannan, Susan Huang, Ting-Yim Lee, Daniel Mendes, Jonathan Thiessen, Christopher Patriquin, Katerina Pavenski
Journal: Blood
Blood (2024) 144 (Supplement 1): 5530.
https://doi.org/10.1182/blood-2024-210952
Published: 2024
Journal Articles

Real-World Clinical Outcomes for Complement Inhibitor Experienced and Naïve Paroxysmal Nocturnal Hemoglobinuria Patients Prescribed Pegcetacoplan in Europe and Canada

Free
Jens Panse, Juan Carlos Vallejo Llamas, Koo Wilson, Zalmai Hakimi, Barbara Czech, Brianne Kerr, Sam Williamson, Jade Garratt-Wheeldon, Yasmin Taylor, Niall Hatchell, Christopher Patriquin
Journal: Blood
Blood (2024) 144 (Supplement 1): 5085.
https://doi.org/10.1182/blood-2024-209732
Published: 2024
Journal Articles

Risk Factors for Thrombotic Events in Patients with PNH: A Nested Case-Control Study in the International PNH Registry

Free
Britta Hoechsmann, Regis Peffault De Latour, MD PhD, Anita Hill, Alexander Röth, MD, Timothy Devos, MD, Christopher Patriquin, Wen-Chien Chou, MD PhD, Deepak Jain, Ke Zu, Jong Wook Lee, MD, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–8.
https://doi.org/10.1182/blood-2020-136767
Published: 2020