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Claude Preudhomme, PharmD, PhD
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Journal Articles

Molecular MRD Monitoring Is Feasible in the Majority of Children with AML and Is Highly Predictive of Outcome: Results from the International MyeChild01 Study

Jelena Jovanovic, PhD, Nicola Potter, PhD, Anju Kanda, MSc, Claire Schwab, PhD, Aimee E Jackson, MSc, Richard Dillon, MA, PhD MRCP, FRCPath, Anna Lawson, BSc, Manohursingh Runglall, MSc, Paresh Vyas, MD PhD, Paul Virgo, Geoff Shenton, Nicholas Heaney, Beki James, MD, Katharine Patrick, MD, Persis J Amrolia, FRCP, FRCPath, PhD, Jean-Hugues Dalle, MD PhD, Gerard Michel, MD, Andrew S. Moore, MBBS,FRACP,PhD, Hélène Lapillonne, MD PhD, Claude Preudhomme, PharmD, PhD, Guy Leverger, MD, Owen P Smith, MD, Andre Baruchel, MD, Yves Bertrand, MD, Arnaud Petit, MD PhD, Keith Wheatley, DPhil, Pamela R. Kearns, PhDFRCPC, Christine J. Harrison, PhD FRCPath, Brenda Gibson, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1393.
https://doi.org/10.1182/blood-2019-125257
Published: 2019
Journal Articles

Prognostic Significance of Concurrent Gene Mutations in Intensively Treated Patients with IDH1/2 Mutated AML

Matthieu Duchmann, Jean-Baptiste Micol, MD, Nicolas Duployez, PharmD, PhD, Emmanuel Raffoux, MD, Xavier Thomas, MD PhD, Jean-Pierre Marolleau, MD PhD, Thorsten Braun, MD, Lionel Ades, MD PhD, Sylvain Chantepie, MD, Emilie Lemasle, MD, Celine Berthon, MD PhD, Jean Valère Malfuson, MD, Cecile Pautas, MD, Juliette Lambert, MD, Nicolas Boissel, MD PhD, Karine Celli-Lebras, CRA, Denis Caillot, MD, Pascal Turlure, MD, Norbert Vey, MD PhD, Arnaud Pigneux, Christian Recher, MD PhD, Christine Terré, PharmD, PhD, Claude Gardin, Raphael Itzykson, MD PhD, Claude Preudhomme, PharmD, PhD, Herve Dombret, MD PhD, Stephane De Botton
Journal: Blood
Blood (2019) 134 (Supplement_1): 1416.
https://doi.org/10.1182/blood-2019-127082
Published: 2019
Journal Articles

Integrating ELN Criteria and a 'Knowledge Bank' Approach to Guide Allogeneic Stem Cell Transplantation (SCT) Indication in Younger Adults with Acute Myeloid Leukemia (AML): An Acute Leukemia French Association Study

Laurène Fenwarth, MD MSc, Raphael Itzykson, MD PhD, Stephane De Botton, MD PhD, Nicolas Duployez, PharmD, PhD, Pierre Sujobert, MD PhD, Céline Berthon, MD PhD, Arnaud Pigneux, Sylvain Chantepie, MD, Christian Recher, MD PhD, Emmanuel Raffoux, MD, Juliette Lambert, MD, Karine Celli-Lebras, CRA, Denis Caillot, MD, Benoit Ducourneau, PharmD, Pascal Turlure, MD, Emilie Lemasle, MD, Cecile Pautas, MD, Norbert Vey, MD PhD, Sylvie Chevret, MD PhD, Christine Terré, PharmD, PhD, Xavier Thomas, MD PhD, Claude Preudhomme, PharmD, PhD, Herve Dombret, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1423.
https://doi.org/10.1182/blood-2019-122468
Published: 2019
Journal Articles

Efficacy and Tolerance of Interferon-α in Hypereosinophilic Syndromes. a Retrospective Multicenter Study on 29 Patients

Pauline De Malglaive, MD, Matthieu Groh, MD, Guillaume Lefèvre, MD PhD, Chafika Morati Hafsaoui, MD, Magda Alexis, MD, Mathilde Hunault, MD PhD, Julien Seneschal, MD PhD, Hilaire Charlanne, MD, Claude Preudhomme, PharmD, PhD, Bernard Bonnotte, MD PhD, Jean Emmanuel Kahn, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2322.
https://doi.org/10.1182/blood-2019-131687
Published: 2019
Journal Articles

A Transcriptomic Continuum of Differentiation Arrest in Acute Leukemia

Jonathan Bond, Aleksandra Krzywon, Ludovic Lhermitte, MD PhD, Christophe Roumier, PharmD, Anne Roggy, Mohamed Belhocine, PhD MSc, BSc, Alexander Kheirallah, Patrick Villarese, PhD, Guillaume Hypolite, Francine Garnache-Ottou, D.Pharm PhD, Herve Dombret, MD PhD, Nicolas Boissel, MD PhD, Claude Preudhomme, PharmD, PhD, Vahid Asnafi, MD PhD, Elisa Laurenti, PhD, Elizabeth Macintyre, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2511.
https://doi.org/10.1182/blood-2019-125902
Published: 2019
Journal Articles

Clinical Spectrum, Long-Term Outcomes and Predictors of Relapse after Imatinib Discontinuation in FIP1L1-Pdgfra-Associated Chronic Eosinophilic Leukemia: Data from 150 Patients

Julien Rohmer, MD, Matthieu Groh, MD, Julie Trichereau, Kewin Panel, Claude Preudhomme, PharmD, PhD, Fanny Legrand, PhD PharmD, Felix Ackermann, MD, Amélie Couteau-Chardon, MD, Mikael Ebbo, MD PhD, Olivier Fain, MD, Lionel Galicier, MD, Mohamed Hamidou, Mathilde Hunault, MD PhD, Etienne Lengline, MD, Catherine Mohr, MD, Franck E Nicolini, MD PhD, Jerome Rey, Louis Terriou, MD, Chafika Morati Hafsaoui, MD, Suzanne Tavitian, MD, Irene Machelart, Katayoun Jondeau, MD, Bertrand Arnulf, Jean-Christophe Ianotto, MD PhD, Jean-Marc Zini, Viviane Dubruille, MD, Francoise Huguet, MD, Borhane Slama, MD, Fabrice Jardin, Didier Adiko, Elise Toussaint, MD, Aurelien Guffroy, MD PhD, Faustine Lhomme, MD PhD, Nathalie Grardel, Cyrielle Gesquieres, Guillaume Lefèvre, MD PhD, Jean Emmanuel Kahn, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 840.
https://doi.org/10.1182/blood-2019-130009
Published: 2019
Journal Articles

The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies

Angela Su, Frank Ling, Camille Vaganay, Bryann Pardieu, Lina Benajiba, MD/PhD, Gaetano Sodaro, Justine Pasanisi, Kevin H Lin, BS, Justine Rutter, PhD, Christopher F. Bassil, Iléana Antony-Debre, PhD, Gabriela Alexe, PhD, Jean-François Benoist, MD, Yana Pikman, MD, Jun Qi, PhD, Herve Dombret, MD PhD, Claude Preudhomme, PharmD, PhD, Nina Fenouille, Hava M. Golan, Kimberly Stegmaier, MD, Camille Lobry, Kris C Wood, PhD, Raphael Itzykson, Alexandre Puissant, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 877.
https://doi.org/10.1182/blood-2019-131255
Published: 2019
Journal Articles

Molecular Profiling Defines Distinct Prognostic Subgroups in Chilhood Acute Myeloid Leukemia: A Report from the French ELAM02 Study Group

Alice Marceau-Renaut, PharmD, Nicolas Duployez, PharmD, PhD, Benoit Ducourneau, PharmD, Myriam Labopin, MD, Arnaud Petit, MD PhD, Alexandra Rousseau, Sandrine Geffroy, PhD, Maxime Bucci, Wendy Cuccuini, Odile Fenneteau, MD, Brigitte Nelken, MD, Stéphane Ducassou, MD, Virginie Gandemer, MDPhD, Thierry Leblanc, MD, Gerard Michel, MD, Yves Bertrand, MD, Andre Baruchel, MD, Guy Leverger, MD PhD, Claude Preudhomme, PharmD, PhD, Hélène Lapillonne, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 403.
https://doi.org/10.1182/blood.V130.Suppl_1.403.403
Published: 2017
Journal Articles

Randomized Phase 2 Trial of Lirilumab (anti-KIR monoclonal antibody, mAb) As Maintenance Treatment in Elderly Patients (pts) with Acute Myeloid Leukemia (AML): Results of the Effikir Trial

Norbert Vey, Pierre-Yves Dumas, MD, Christian Recher, MD PhD, Lauris Gastaud, MD, Bruno Lioure, MD, Claude-Eric Bulabois, MD, Cecile Pautas, Jean-Pierre Marolleau, MD PhD, Stéphane Leprêtre, MD, Emmanuel Raffoux, MD, Xavier Thomas, MD, Yosr Hicheri, Caroline Bonmati, MD, Bruno Quesnel, MD PhD, Philippe Rousselot, Sylvie Castaigne, MD PhD, Eric Jourdan, MD, Jean Valère Malfuson, Gaelle Guillerm, MD, Jean Henri Bouhris, Mario Ojeda, MD, Mathilde Hunault, MD PhD, Norbert Ifrah, MD PhD, Claude Gardin, MD PhD, Andre Delannoy, MD, Lucile Beautier, Carine Paturel, PhD, Pascale Andre, PhD, Robert Zerbib, Claude Preudhomme, PharmD, PhD, Antoine Toubert, MD PhD, Nicolas Dulphy, PhD, Daniel Olive, MD PhD, Arnaud Pigneux, MD, Herve Dombret, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 889.
https://doi.org/10.1182/blood.V130.Suppl_1.889.889
Published: 2017
Journal Articles

Early Detection of WT1 minimal Residual Disease Predicts Outcome in Acute Myeloid Leukemia and Identify Patients with High Risk of Relapse Independently of Allogeneic Stem Cell Transplantation

Juliette Lambert, Jérôme Lambert, MDPhD, Xavier Thomas, MD, Alice Marceau-Renaut, PharmD, Aline Renneville, MDPhD, Marie-Magdelaine Coude, MD, Sandrine Hayette, MD, Christian Recher, MD PhD, Emmanuel Raffoux, MD, Arnaud Pigneux, MD PhD, Céline Berthon, MD PhD, Christine Terré, PharmD, PhD, Karine Celli-Lebras, CRA, Sylvie Castaigne, MD, Nicolas Boissel, MD PhD, Philippe Rousselot, Herve Dombret, MD, Claude Preudhomme, PharmD, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 29.
https://doi.org/10.1182/blood.V130.Suppl_1.29.29
Published: 2017
Journal Articles

Targeting Aberrant Expression of CD81 Impacts Cell Adhesion and Migration, Drug Resistance and Prognosis of Acute Myeloid Leukemia

Fanny Gonzales, Thomas Boyer, Pauline Peyrouze, Soizic Guihard, Christophe Roumier, Céline Berthon, MD PhD, Claude Preudhomme, PharmD, PhD, Meyling Cheok, BSPharm, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2675.
https://doi.org/10.1182/blood.V130.Suppl_1.2675.2675
Published: 2017
Journal Articles

Clonal Interference of Signaling Mutations Holds Prognostic Relevance in Core Binding Factor (CBF) Acute Myeloid Leukemia (AML)

Raphael Itzykson, MD PhD, Nicolas Duployez, PharmD, PhD, Annette Fasan, PhD, Alice Marceau-Renaut, PharmD, Manja Meggendorfer, PhD, Eric Jourdan, MD, Arnaud Petit, MD PhD, Hélène Lapillonne, MD PhD, Jean-Baptiste Micol, MD PhD, Pascale Cornillet-Lefebvre, Norbert Ifrah, MD, Guy Leverger, MD PhD, Herve Dombret, MD, Nicolas Boissel, MD PhD, Torsten Haferlach, MD, Claude Preudhomme, PharmD, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 26.
https://doi.org/10.1182/blood.V130.Suppl_1.26.26
Published: 2017
Journal Articles

Role of Allogeneic Reduced Intensity Conditioning Stem Cell Transplantation (RIC-SCT) in Older Patients with Acute Myeloid Leukemia (AML): Analysis of the ALFA-1200 Study

Claude Gardin, Cécile Pautas, Emilie Lemasle, MD, Jean-Henri Bourhis, Lionel Ades, MD PhD, Jean-Pierre Marolleau, MD PhD, Jean Valère Malfuson, Lauris Gastaud, MD, Emmanuel Raffoux, MD, Isabel Cano, Thorsten Braun, MD PhD, Xavier Thomas, MD, Sylvain Chantepie, Thomas Cluzeau, MDPhD, Stephane De Botton, Céline Berthon, MD PhD, Benjamin Papoular, Nicolas Boissel, MD PhD, Claude Preudhomme, PharmD, PhD, Christine Terré, PharmD, PhD, Gérard Socié, MDPhD, Mauricette Michallet, MD PhD, Ibrahim Yakoub-Agha, Karine Celli-Lebras, CRA, Herve Dombret, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 466.
https://doi.org/10.1182/blood.V130.Suppl_1.466.466
Published: 2017
Journal Articles

Clofarabine-Based Consolidation Improves Relapse-Free Survival of Patients with Acute Myeloid Leukemia with Complex or Micro-Complex Karyotype: Results from the Randomized ALFA-0702 Study

Laurène Fenwarth, MSc, MD, Nicolas Duployez, PharmD, PhD, Xavier Thomas, MD, Nicolas Boissel, MD PhD, Sandrine Geffroy, PhD, Alice Marceau-Renaut, PharmD, Denis Caillot, MD, Emmanuel Raffoux, MD, Emilie Lemasle, MD, Jean-Pierre Marolleau, MD PhD, Céline Berthon, MD PhD, Meyling H. Cheok, MSPharm, PhD, Pauline Peyrouze, Arnaud Pigneux, MD PhD, Norbert Vey, Karine Celli-Lebras, CRA, Christine Terré, PharmD, PhD, Claude Preudhomme, PharmD, PhD, Herve Dombret, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 465.
https://doi.org/10.1182/blood.V130.Suppl_1.465.465
Published: 2017
Journal Articles

Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia (CMML) Patients Treated with Hypomethylating Agents. a Report on 183 Patients

Matthieu Duchmann, Fevzi Yalniz, MD, Alessandro Sanna, David A Sallman, MD, Catherine C. Coombs, MD, Aline Renneville, MDPhD, Olivier Kosmider, Thorsten Braun, MD PhD, Uwe Platzbecker, MD, Lise Willems, MD, Lionel Ades, MD PhD, Michaela Fontenay, MD PhD, Raajit K. Rampal, MD PhD, Eric Padron, MD, Nathalie Droin, Claude Preudhomme, PharmD, PhD, Valeria Santini, MD, Mrinal M. Patnaik, MDMBBS, Pierre Fenaux, MD PhD, Éric Solary, MD PhD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 159.
https://doi.org/10.1182/blood.V130.Suppl_1.159.159
Published: 2017
Journal Articles

Granulomonocytic Progenitors (GMPs) Are Key Target Cells of Azacitidine in MDS and AML

Ashfaq Ali, PhD, Justine Penneroux, Reinaldo Dal Bello Jr, Aline Massé, Samuel Quentin, Ashwin Unnikrishnan, PhD, Lucie Hernandez, Emmanuel Raffoux, MD, Raouf Benabelali, Aline Renneville, MDPhD, Claude Preudhomme, PharmD, PhD, John Pimanda, PhDFRACP,FRCPA,MBBS, Herve Dombret, MD, Jean Soulier, MDPhD, Pierre Fenaux, MD PhD, Emmanuelle Clappier, PharmD,PhD, Lionel Ades, MD PhD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 587.
https://doi.org/10.1182/blood.V130.Suppl_1.587.587
Published: 2017
Journal Articles

Efficacy of 5-Azacitidine on IDH1/2 Acute Myeloid Leukemia/Myelodysplastic Syndromes and Correlation with 2-Hydroxyglutarate Production

Christophe Willekens, MD, Veronique Saada, Sophie Broutin, Julia Delahousse, Aline Renneville, MDPhD, Cynthia Petrovanu, Christophe Marzac, Jean-Baptiste Micol, MD PhD, Éric Solary, MD PhD, Florence Pasquier, MD PhD, Julien Lazarovici, MD, Vincent Ribrag, Claude Preudhomme, PharmD, PhD, Cyril Quivoron, Virginie Penard-Lacronique, PhD, Angelo Paci, Stephane de Botton, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1313.
https://doi.org/10.1182/blood.V130.Suppl_1.1313.1313
Published: 2017
Journal Articles

Outcome of NPM1 Mutated Acute Myeloid Leukemia (AML) Treated with Hypomethylating Agents (HMAs): A Report on 71 Cases

Pedro H Prata, MD, Cecile Bally, Thomas Prebet, MD PhD, Christian Recher, MD PhD, Geoffroy Venton, Xavier Thomas, MD, Emmanuel Raffoux, MD, Arnaud Pigneux, MD PhD, Thomas Cluzeau, MDPhD, Judith Desoutter, Julie Gay, Claude Preudhomme, PharmD, PhD, Pierre Fenaux, MD PhD, Lionel Ades, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1335.
https://doi.org/10.1182/blood.V130.Suppl_1.1335.1335
Published: 2017
Journal Articles

Epidemiology of Adults AML in Nord-Pas De Calais and Picardy

Christophe Roumier, MD, Céline Rodriguez, Cécile Frimat, Céline Berthon, MD PhD, Carole Delattre, MD, Marc Wetterwald, MD PhD, Jose Fernandes, MD, Agnes Daudignon, Isabelle Plantier, MD, Agnes Charpentier, MD, Stéphane Darre, MD, Bachra Choufi, MD, Laure Stalnikiewicz, MD, Christine Ghevaert, MD, Jean-Pierre Marolleau, MD PhD, Veronique Harrivel, MD, Olivier Nibourel, PhD, Catherine Roche, PhD, Bruno Quesnel, MD PhD, Claude Preudhomme, PharmD, PhD
Journal: Blood
Blood (2014) 124 (21): 2281.
https://doi.org/10.1182/blood.V124.21.2281.2281
Published: 2014
Journal Articles

Prognostic Analysis of GATA2 Mutations in CEBPA -Mutated Acute Myeloid Leukemia

Alice Marceau-Renaut, Meyling Cheok, Nicolas Duployez, Olivier Nibourel, Nathalie Helevaut, Céline Rodriguez, Karine Celli-Lebras, Céline Berthon, Guy Leverger, MD, Nicolas Boissel, MD PhD, Christine Terré, Xavier Thomas, Sylvie Castaigne, Herve Dombret, Claude Preudhomme, PharmD, PhD, Aline Renneville
Journal: Blood
Blood (2014) 124 (21): 2360.
https://doi.org/10.1182/blood.V124.21.2360.2360
Published: 2014