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Journal Articles

Deterministic Cell Separation Recovers >2-Fold T Cells, and More Naïve T Cells, for Autologous Cell Therapy As Compared to Centrifugally Prepared Cells

Yasna Behmardi, Laurissa Ouaguia, Laura Jean Healey, MinJung Kim, Cole Jones, Hani Rahmo, Alison Skelley, Khushroo Gandhi, Roberto Campos-Gonzalez, Curt I Civin, Tony Ward

Blood (2021) 138 (Supplement 1): 2847.

https://doi.org/10.1182/blood-2021-153528

Published: 2021

Journal Articles

Use of Multi-Omics Approach to Produce a Robust Serum-Free Media for the Expansion of T Cells

Sarya G. Mansour, M.A, Pei-Yi Lin, PhD, Anson Pierce, PhD, Curt I Civin, MD

Blood (2019) 134 (Supplement_1): 1053.

https://doi.org/10.1182/blood-2019-124393

Published: 2019

Journal Articles

Optimized Culture Medium for Enhanced Ex Vivo expansion of Human Hematopoietic Stem Cells

Janet J Sei, PhD, Blake S Moses, PhD, Abigail Harris-Becker, MS, MinJung Kim, PhD, Navjot Kaur, PhD, Mohan C Vemuri, PhD, Curt I Civin, MD

Blood (2019) 134 (Supplement_1): 1965.

https://doi.org/10.1182/blood-2019-126174

Published: 2019

Journal Articles

SIX1 Transcription Factor Enhances Human Erythropoiesis Via GATA1

Michael Creed, MSc, Christian Eberly, Jevon Cutler, PhD, MinJung Kim, PhD, Akhilesh Pandey, MD PhD, Curt I Civin, MD, Tami J Kingsbury, PhD

Blood (2019) 134 (Supplement_1): 3503.

https://doi.org/10.1182/blood-2019-131203

Published: 2019

Journal Articles

The 3-Drug Combination Treatment ART838, ABT199 Plus Sorafenib Is Effective Against AML Xenografts, Possibly Via Cooperative Targeting of MCL1

Blake S Moses, PhD, Jennifer Fox, PhD, Xiaochun Chen, PhD, Samantha McCullough, BS, Sang Ngoc Tran, BA, Allison Kirkpatrick, BS, Kalyani Kumar, BS, Jeffrey W. Tyner, PhD, Gary H. Posner, PhD, Curt I. Civin, MD

Blood (2018) 132 (Supplement 1): 4044.

https://doi.org/10.1182/blood-2018-99-113040

Published: 2018

Journal Articles

DNA Demethylating Agents Generate a Brcaness Effect in Multiple Sporadic Tumor Types: Prediction for Sensitivity to PARP Inhibitors in AML

Aksinija A Kogan, BS, MS, Lena J Mclaughlin, BS, Michael Topper, BS, Nidal Muvarak, PhD, Lora Stojanovic, BS, T Michael Creed, BS, MS, Soren Bentzen, PhD DMSc, Curt I. Civin, MD, Maria R. Baer, MD, Tami J Kingsbury, PhD, Stephen Baylin, MD, Feyruz V. Rassool, BSc, PhD

Blood (2017) 130 (Supplement 1): 3347.

https://doi.org/10.1182/blood.V130.Suppl_1.3347.3347

Published: 2017

Journal Articles

Artemisinins Synergize with BCL2 Inhibitors By Reducing MCL1 Protein Levels in Leukemia Cells

Blake S Moses, PhD, Jennifer Fox, PhD, Xiaochun Chen, PhD, Samantha McCullough, BS, Allison Kirkpatrick, BS, Kalyani Kumar, BS, Jeffrey W. Tyner, PhD, Gary H. Posner, PhD, Curt I. Civin, MD

Blood (2017) 130 (Supplement 1): 3827.

https://doi.org/10.1182/blood.V130.Suppl_1.3827.3827

Published: 2017

Journal Articles

RAB14 Regulates Human Erythropoiesis and Megakaryopoiesis

Minjung Kim, PhD, Tami J. Kingsbury, PhD, Curt I. Civin, MD

Blood (2016) 128 (22): 2661.

https://doi.org/10.1182/blood.V128.22.2661.2661

Published: 2016

Journal Articles

Nrf2 Regulates Sensitivity of Leukemias to Artemisinins

Jennifer Bai, BA, Xiaochun Chen, PhD, Curt I. Civin, MD

Blood (2016) 128 (22): 2324.

https://doi.org/10.1182/blood.V128.22.2324.2324

Published: 2016

Journal Articles

RAB14 and RAB5 Gtpases Regulate Human Erythropoiesis, Potentially Via Opposing Roles in Endosomal Recycling

MinJung Kim, PhD, Tami J. Kingsbury, PhD, Wen-Chih Cheng, PhD, Yee Sun Tan, PhD, Brittany M. Taylor, Sampada Koshatwar, Curt I. Civin, MD

Blood (2015) 126 (23): 937.

https://doi.org/10.1182/blood.V126.23.937.937

Published: 2015

Journal Articles

Gene Expression and Mutation Analysis (GEMA) –Guided Precision Medicine Targeting PARP1 to Induce Synthetic Lethality in DNA-PK –Deficient Quiescent and BRCA-Deficient Proliferating Leukemia Stem and Progenitor Cells

Margaret Nieborowska-Skorska, MD PhD, Katherine Sullivan, Paulina Podszywalow-Bartnicka, Grazyna Hoser, PhD, Elisabeth Bolton-Gillespie, Kimberly Cramer-Morales, Artur Slupianek, PhD, Chun Zhou, PhD, Sabine Cerny-Reiterer, DVM, Tomasz Stoklosa, MD PhD, Stephen M. Sykes, PhD, Peter Valent, MD, Curt I. Civin, MD, Markus Muschen, MD PhD, Mark D. Minden, MD PhD, Kolja Eppert, PhD, Tomasz Skorski, MD PhD

Blood (2014) 124 (21): 480.

https://doi.org/10.1182/blood.V124.21.480.480

Published: 2014

Journal Articles

Integrated Analysis Of CRLF2 Signaling In Acute Lymphoblastic Leukemia Identifies Polo-Like Kinase 1 As a Therapeutic Target

Tai-Chung Huang, M.D., Shubhada Shashikant Bharne, Ph.D., Jevon Cutler, Jun Zhong, Ph.D., David M. Weinstock, MD, Jeffrey W. Tyner, Curt I. Civin, M.D., Akhilesh Pandey, M.D., Ph.D.

Blood (2013) 122 (21): 2667.

https://doi.org/10.1182/blood.V122.21.2667.2667

Published: 2013

Journal Articles

Interleukin-6 Reduces Erythroid Development and Mitochondrial Membrane Potential In Human Erythroleukemic Cells

Bryan J. McCranor, PhD, MinJung Kim, PhD, Nicole M Cruz, Qian-Li Xue, PhD, Alan E. Berger, PhD, Jeremy D. Walston, M.D., Curt I. Civin, M.D., Cindy N. Roy, PhD

Blood (2013) 122 (21): 3420.

https://doi.org/10.1182/blood.V122.21.3420.3420

Published: 2013

Journal Articles

MiR-144 and MiR-451 Regulate Human Erythropoiesis By Targeting RAB14

MinJung Kim, PhD, Yee Sun Tan, Wen-Chih Cheng, PhD, Curt I. Civin, M.D.

Blood (2013) 122 (21): 942.

https://doi.org/10.1182/blood.V122.21.942.942

Published: 2013

Journal Articles

Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile

Kimberly Cramer-Morales, Margaret Nieborowska-Skorska, Kara Scheibner, Michelle Padget, David A. Irvine, Tomasz Sliwinski, Kimberly Haas, Jaewoong Lee, Huimin Geng, Darshan Roy, Artur Slupianek, Feyruz V. Rassool, Mariusz A. Wasik, Wayne Childers, Mhairi Copland, Markus Müschen, Curt I. Civin, Tomasz Skorski

Blood (2013) 122 (7): 1293–1304.

https://doi.org/10.1182/blood-2013-05-501072

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

Interleukin-6 Is a Significant Modifier of the Anemia Associated with Aging in Mice.

Bryan J. McCranor, PhD, Jacqueline M. Langdon, Olivier D. Prince, M.D., Qilu Yu, Ph.D., Alan E. Berger, PhD, Chris Cheadle, PhD, Curt I. Civin, MD, Jeremy D. Walston, M.D., Qian-Li Xue, PhD, Cindy N. Roy, PhD

Blood (2012) 120 (21): 2094.

https://doi.org/10.1182/blood.V120.21.2094.2094

Published: 2012

Journal Articles

FLT3-ITD Knock-in Impairs Hematopoietic Stem Cell Quiescence/Homeostasis, Leading to a Myeloproliferative Neoplasm

S. Haihua Chu, Diane Heiser, Li Li, PhD, Ian M Kaplan, PhD, David Huso, D.V.M., Ph.D., Curt I. Civin, MD, Donald Small, MD, PhD

Blood (2011) 118 (21): 46.

https://doi.org/10.1182/blood.V118.21.46.46

Published: 2011

Journal Articles

MicroRNA Maestros of Hematopoiesis

Kara A. Scheibner, PhD, Diane Heiser, Ian M Kaplan, Wen-Chih Cheng, PhD, MinJung Kim, PhD, Shubhada Shashikant Bharne, PhD, Sebastien Morisot, PhD, Curt I. Civin, MD

Blood (2010) 116 (21): SCI-32.

https://doi.org/10.1182/blood.V116.21.SCI-32.SCI-32

Published: 2010

Journal Articles

The Mir-23a∼Mir-27a∼Mir-24 Cluster Acts as a Tumor Suppressor In Leukemias by Post-Transcriptional Regulation of 14-3-3 Proteins

Kara A. Scheibner, PhD, Brie Teaboldt, Mary Claire Hauer, Curt I. Civin, MD

Blood (2010) 116 (21): 3145.

https://doi.org/10.1182/blood.V116.21.3145.3145

Published: 2010

Journal Articles

Shortened Erythrocyte Life Span and Increased Oxidative Stress In Erythroid Precursors Are Consistent with Normocytic Anemia In Mice with Chronic Inflammation

Andrew J. Layman, Jacqueline M. Langdon, Qilu Yu, Ph.D., Olivier D. Prince, M.D., Jeremy D. Walston, M.D., Curt I. Civin, MD, Cindy N. Roy, PhD

Blood (2010) 116 (21): 3205.

https://doi.org/10.1182/blood.V116.21.3205.3205

Published: 2010

NARROW

Deterministic Cell Separation Recovers >2-Fold T Cells, and More Naïve T Cells, for Autologous Cell Therapy As Compared to Centrifugally Prepared Cells

Use of Multi-Omics Approach to Produce a Robust Serum-Free Media for the Expansion of T Cells

Optimized Culture Medium for Enhanced Ex Vivo expansion of Human Hematopoietic Stem Cells

SIX1 Transcription Factor Enhances Human Erythropoiesis Via GATA1

The 3-Drug Combination Treatment ART838, ABT199 Plus Sorafenib Is Effective Against AML Xenografts, Possibly Via Cooperative Targeting of MCL1

DNA Demethylating Agents Generate a Brcaness Effect in Multiple Sporadic Tumor Types: Prediction for Sensitivity to PARP Inhibitors in AML

Artemisinins Synergize with BCL2 Inhibitors By Reducing MCL1 Protein Levels in Leukemia Cells

RAB14 Regulates Human Erythropoiesis and Megakaryopoiesis

Nrf2 Regulates Sensitivity of Leukemias to Artemisinins

RAB14 and RAB5 Gtpases Regulate Human Erythropoiesis, Potentially Via Opposing Roles in Endosomal Recycling

Gene Expression and Mutation Analysis (GEMA) –Guided Precision Medicine Targeting PARP1 to Induce Synthetic Lethality in DNA-PK –Deficient Quiescent and BRCA-Deficient Proliferating Leukemia Stem and Progenitor Cells

Integrated Analysis Of CRLF2 Signaling In Acute Lymphoblastic Leukemia Identifies Polo-Like Kinase 1 As a Therapeutic Target

Interleukin-6 Reduces Erythroid Development and Mitochondrial Membrane Potential In Human Erythroleukemic Cells

MiR-144 and MiR-451 Regulate Human Erythropoiesis By Targeting RAB14

Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile

Interleukin-6 Is a Significant Modifier of the Anemia Associated with Aging in Mice.

FLT3-ITD Knock-in Impairs Hematopoietic Stem Cell Quiescence/Homeostasis, Leading to a Myeloproliferative Neoplasm

MicroRNA Maestros of Hematopoiesis

The Mir-23a∼Mir-27a∼Mir-24 Cluster Acts as a Tumor Suppressor In Leukemias by Post-Transcriptional Regulation of 14-3-3 Proteins

Shortened Erythrocyte Life Span and Increased Oxidative Stress In Erythroid Precursors Are Consistent with Normocytic Anemia In Mice with Chronic Inflammation

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American Society of Hematology

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American Society of Hematology

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