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Mariusz A. Wasik
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Journal Articles

DNA Polymerase Theta Protects Leukemia Cells from Metabolic-Induced DNA Damage

Umeshkumar M Vekariya, Katherine Sullivan-Reed, Monika Toma, Margaret Nieborowska-Skorska, Bac Viet Le, Marie-Christine Caron, Anna-Mariya Kukuyan, Paulina Podszywalow-Bartnicka, Kumaraswamy Chitrala, Jessica Atkins, Malgorzata Drzewiecka, Wanjuan Feng, Joe Chan, Konstantin Golovine, Jaroslav Jelinek, Tomasz Sliwinski, Jayashri Ghosh, Ksenia Maslawska-Wasowska, Reza Nejati, Mariusz A Wasik, Stephen M. Sykes, Katarzyna Piwocka, Emir Hadzijusufovic, Peter Valent, Richard Pomerantz, George Morton, Wayne Childers, Huaqing Zhao, Elisabeth Paietta, Ross L. Levine, Martin S. Tallman, Hugo F Fernandez, Mark R. Litzow, Gaorav P Gupta, Jean-Yves Masson, Tomasz Skorski
Journal: Blood
Blood (2022) 140 (Supplement 1): 2972–2974.
https://doi.org/10.1182/blood-2022-156458
Published: 2022
Journal Articles

SHP1 Loss Augments DLBCL Cellular Response to Ibrutinib: A Candidate Predictive Biomarker

Y. Lynn Wang, Ji Ma, Vinay Mallikarjuna, Pin Lu, Shengchun Wang, Sahar Poureghbali, Mariusz A Wasik, Reza Nejati, Wenjun Wu
Journal: Blood
Blood (2021) 138 (Supplement 1): 3490.
https://doi.org/10.1182/blood-2021-146086
Published: 2021
Journal Articles

Transdifferentiation of lymphoma into sarcoma associated with profound reprogramming of the epigenome

Qian Zhang, Elena J. Orlando, Hong Y. Wang, Agata M. Bogusz, Xiaobin Liu, Simon F. Lacey, Honore T. Strauser, Selene Nunez-Cruz, Reza Nejati, Paul Zhang, Sarah Brooks, Christopher Watt, J. Joseph Melenhorst, Carl H. June, Stephen J. Schuster, Mariusz A. Wasik
Journal: Blood
Blood (2020) 136 (17): 1980–1983.
https://doi.org/10.1182/blood.2020005123
Published: 2020
Includes: Supplemental data
Journal Articles

Antibiotics inhibit tumor and disease activity in cutaneous T-cell lymphoma

Lise M. Lindahl, Andreas Willerslev-Olsen, Lise M. R. Gjerdrum, Pia R. Nielsen, Edda Blümel, Anne H. Rittig, Pamela Celis, Bjorn Herpers, Jürgen C. Becker, Birgitte Stausbøl-Grøn, Mariusz A. Wasik, Maria Gluud, Simon Fredholm, Terkild B. Buus, Claus Johansen, Claudia Nastasi, Lukas Peiffer, Linda Kubat, Michael Bzorek, Jens O. Eriksen, Thorbjørn Krejsgaard, Charlotte M. Bonefeld, Carsten Geisler, Tomas Mustelin, Erik Langhoff, Michael Givskov, Anders Woetmann, Mogens Kilian, Thomas Litman, Lars Iversen, Niels Odum
Journal: Blood
Blood (2019) 134 (13): 1072–1083.
https://doi.org/10.1182/blood.2018888107
Published: 2019
Includes: Supplemental data
Journal Articles

Tyrosine kinase inhibitor–induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors

Silvia Maifrede, Margaret Nieborowska-Skorska, Katherine Sullivan-Reed, Yashodhara Dasgupta, Paulina Podszywalow-Bartnicka, Bac Viet Le, Martyna Solecka, Zhaorui Lian, Elizaveta A. Belyaeva, Alina Nersesyan, Marcin M. Machnicki, Monika Toma, Nicolas Chatain, Malgorzata Rydzanicz, Huaqing Zhao, Jaroslav Jelinek, Katarzyna Piwocka, Tomasz Sliwinski, Tomasz Stoklosa, Rafal Ploski, Thomas Fischer, Stephen M. Sykes, Steffen Koschmieder, Lars Bullinger, Peter Valent, Mariusz A. Wasik, Jian Huang, Tomasz Skorski
Journal: Blood
Blood (2018) 132 (1): 67–77.
https://doi.org/10.1182/blood-2018-02-834895
Published: 2018
Includes: Supplemental data
Journal Articles

Distinct miRNA profile in prognosis of early CTCL

Mariusz A. Wasik
Journal: Blood
Blood (2018) 131 (7): 711.
https://doi.org/10.1182/blood-2017-12-821520
Published: 2018
Journal Articles

Cytokine release syndrome associated with chimeric-antigen receptor T-cell therapy: clinicopathological insights

Clinical Trials & Observations
Amrom E. Obstfeld, Noelle V. Frey, Keith Mansfield, Simon F. Lacey, Carl H. June, David L. Porter, Jan J. Melenhorst, Mariusz A. Wasik
Journal: Blood
Blood (2017) 130 (23): 2569–2572.
https://doi.org/10.1182/blood-2017-08-802413
Published: 2017
Includes: Supplemental data
Journal Articles

Nucleophosmin-anaplastic lymphoma kinase: the ultimate oncogene and therapeutic target

Michael T. Werner, Chen Zhao, Qian Zhang, Mariusz A. Wasik
Journal: Blood
Blood (2017) 129 (7): 823–831.
https://doi.org/10.1182/blood-2016-05-717793
Published: 2017
Journal Articles

IGH/MYC Translocation in Burkitt Lymphoma Is Associated with BRCA2 Deficiency and Synthetic Lethality By PARP1 Inhibitors

Silvia Maifrede, Kayla Martin, Paulina Podszywalow-Bartnicka, PhD, Sullivan Katherine, Samantha Langer, Reza Nejati, Yashodhara Dasgupta, Daniel Gritsyuk, Margaret Nieborowska-Skorska, Lena Lupey, Katarzyna Piwocka, Mariusz A Wasik, MD, Italo Tempera, Tomasz Skorski
Journal: Blood
Blood (2016) 128 (22): 4111.
https://doi.org/10.1182/blood.V128.22.4111.4111
Published: 2016
Journal Articles

Treatment with Chimeric Antigen Receptor Modified T Cells Directed Against CD19 (CTL019) Results in Durable Remissions in Patients with Relapsed or Refractory Diffuse Large B Cell Lymphomas of Germinal Center and Non-Germinal Center Origin, "Double Hit" Diffuse Large B Cell Lymphomas, and Transformed Follicular to Diffuse Large B Cell Lymphomas

Stephen J. Schuster, MD, Jakub Svoboda, MD, Sunita Dwivedy Nasta, MD, Elise A. Chong, MD, Nicole Winchell, Daniel J. Landsburg, MD, David L. Porter, MD, Anthony R. Mato, MD, Honore T Strauser, April M. Schrank-Hacker, Mariusz A Wasik, MD, Simon Francis Lacey, PhD BS, Jan Joseph Melenhorst, PhD, Anne Chew, PhD, Jens Hasskarl, MD PhD, Katherine T. Marcucci, PhD, Bruce L Levine, PhD, Carl H June, MD
Journal: Blood
Blood (2016) 128 (22): 3026.
https://doi.org/10.1182/blood.V128.22.3026.3026
Published: 2016
Journal Articles

Overcoming the Immunosuppressive Tumor Microenvironment of Hodgkin Lymphoma Using Chimeric Antigen Receptor T Cells

Marco Ruella, MD, Michael Klichinsky, PharmD, Saad S Kenderian, MD, Olga Shestova, PhD, Amy Ziober, Michael D Feldman, MD, Mariusz A Wasik, MD, Carl H June, MD, Saar I Gill, MBBS, PhD
Journal: Blood
Blood (2016) 128 (22): 43.
https://doi.org/10.1182/blood.V128.22.43.43
Published: 2016
Journal Articles

Kinase Inhibitor Ibrutinib Prevents Cytokine-Release Syndrome after Anti-CD19 Chimeric Antigen Receptor T Cells (CART) for B Cell Neoplasms

Marco Ruella, MD, Saad S Kenderian, MD, Olga Shestova, PhD, Michael Klichinsky, PharmD, J. Joseph Melenhorst, PhD, Mariusz A Wasik, MD, Simon F. Lacey, PhD, Carl H June, MD, Saar I Gill, MBBS, PhD
Journal: Blood
Blood (2016) 128 (22): 2159.
https://doi.org/10.1182/blood.V128.22.2159.2159
Published: 2016
Journal Articles

Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy

Clinical Trials & Observations
Vijay G. Bhoj, Dimitrios Arhontoulis, Gerald Wertheim, James Capobianchi, Colleen A. Callahan, Christoph T. Ellebrecht, Amrom E. Obstfeld, Simon F. Lacey, Jan J. Melenhorst, Farzana Nazimuddin, Wei-Ting Hwang, Shannon L. Maude, Mariusz A. Wasik, Adam Bagg, Stephen Schuster, Michael D. Feldman, David L. Porter, Stephen A. Grupp, Carl H. June, Michael C. Milone
Journal: Blood
Blood (2016) 128 (3): 360–370.
https://doi.org/10.1182/blood-2016-01-694356
Published: 2016
Includes: Supplemental data
Journal Articles

Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases

Yashodhara Dasgupta, Mateusz Koptyra, Grazyna Hoser, Kanchan Kantekure, Darshan Roy, Barbara Gornicka, Margaret Nieborowska-Skorska, Elisabeth Bolton-Gillespie, Sabine Cerny-Reiterer, Markus Müschen, Peter Valent, Mariusz A. Wasik, Christine Richardson, Oliver Hantschel, Heiko van der Kuip, Tomasz Stoklosa, Tomasz Skorski
Journal: Blood
Blood (2016) 127 (17): 2131–2143.
https://doi.org/10.1182/blood-2015-11-681171
Published: 2016
Includes: Supplemental data
Journal Articles

Staphylococcal enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma

Andreas Willerslev-Olsen, Thorbjørn Krejsgaard, Lise M. Lindahl, Ivan V. Litvinov, Simon Fredholm, David L. Petersen, Claudia Nastasi, Robert Gniadecki, Nigel P. Mongan, Denis Sasseville, Mariusz A. Wasik, Charlotte M. Bonefeld, Carsten Geisler, Anders Woetmann, Lars Iversen, Mogens Kilian, Sergei B. Koralov, Niels Odum
Journal: Blood
Blood (2016) 127 (10): 1287–1296.
https://doi.org/10.1182/blood-2015-08-662353
Published: 2016
Journal Articles

The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Engraftment and Antitumor Responses Against Mantle Cell Lymphoma

Marco Ruella, MD, Saad S Kenderian, MD, Olga Shestova, PhD, Joseph A. Fraietta, PhD, Sohail Qayyum, MD, Qian Zhang, MD PhD, Marcela V. Maus, MDPhD, Xiaobin Liu, PhD, Selene Nunez-Cruz, PhD, Michael Klichinsky, PharmD, Omkar Uday Kawalekar, MS, BS, Michael C. Milone, MD PhD, Simon F. Lacey, PhD BSc, Anthony Mato, MD, Stephen J. Schuster, MD, Michael Kalos, PhD, Carl H. June, MD, Saar I Gill, MBBS, PhD, Mariusz A. Wasik, MD
Journal: Blood
Blood (2015) 126 (23): 704.
https://doi.org/10.1182/blood.V126.23.704.704
Published: 2015
Journal Articles

Sustained Remissions Following Chimeric Antigen Receptor Modified T Cells Directed Against CD19 (CTL019) in Patients with Relapsed or Refractory CD19+ Lymphomas

Stephen J. Schuster, MD, Jakub Svoboda, MD, Sunita Dwivedy Nasta, MD, David L. Porter, MD, Elise A. Chong, MD, Daniel J. Landsburg, MD, Anthony R. Mato, MD MSCE, Simon F. Lacey, PhD BS, Jan J. Melenhorst, PhD, Anne Chew, PhD, Jens Hasskarl, MD PhD, Gaurav D. Shah, MD, Mariusz A. Wasik, MD, Katherine T. Marcucci, PhD, Zhaohui Zheng, MS, Bruce L. Levine, PhD, Carl H. June, MD
Journal: Blood
Blood (2015) 126 (23): 183.
https://doi.org/10.1182/blood.V126.23.183.183
Published: 2015
Journal Articles

IL-13 as a novel growth factor in CTCL

Mariusz A. Wasik
Journal: Blood
Blood (2015) 125 (18): 2737–2738.
https://doi.org/10.1182/blood-2015-02-626432
Published: 2015
Journal Articles

Phase IIa Trial of Chimeric Antigen Receptor Modified T Cells Directed Against CD19 (CTL019) in Patients with Relapsed or Refractory CD19+ Lymphomas

Stephen J. Schuster, MD, Jakub Svoboda, MD, Sunita Dwivedy Nasta, MD, David L. Porter, MD, Elise A. Chong, MD, Yolanda Mahnke, PhD, Simon F. Lacey, PhD BSc, J. Joseph Melenhorst, PhD, Anne Chew, PhD, Gaurav Shah, MD, Jens Hasskarl, MD, Manuel Litchman, MD, Mariusz A. Wasik, MD, Daniel J. Landsburg, MD, Anthony R. Mato, MD MSCE, Alfred L. Garfall, MD, Noelle V. Frey, MDMS, Katherine T. Marcucci, PhD, Joanne Shea, RN, Holly McConville, RN, BSN, Zhaohui Zheng, Bruce L. Levine, PhD, Carl H. June, MD
Journal: Blood
Blood (2014) 124 (21): 3087.
https://doi.org/10.1182/blood.V124.21.3087.3087
Published: 2014
Journal Articles

Novel Chimeric Antigen Receptor T Cells for the Treatment of Hodgkin Lymphoma

Marco Ruella, MD, Saad S Kenderian, MD, Olga Shestova, PhD, Taylor Chen, John Scholler, Mariusz A. Wasik, MD, Carl H. June, MD, Saar I. Gill, MD PhD
Journal: Blood
Blood (2014) 124 (21): 806.
https://doi.org/10.1182/blood.V124.21.806.806
Published: 2014