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Dena S. Leeman
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Journal Articles

EXEL-8232, a Small Molecule JAK2 Inhibitor, Effectively Treats Thrombocytosis and Extramedullary Hematopoiesis in a Murine Model of Myeloproliferative Disease Induced by MPLW515L

Gerlinde Wernig, Michael G. Kharas, Dena S. Leeman, Rachel Okabe, Maricel Gozo, Mahnaz Paktinat, Erika Haydu, Brian Ball, Tulasi Khandan, Douglas O. Clary, D Gary Gilliland
Journal: Blood
Blood (2008) 112 (11): 3741.
https://doi.org/10.1182/blood.V112.11.3741.3741
Published: 2008
Journal Articles

p16 INK4a Is a Key Downstream Mediator of the Deleterious Effects of FoxO Deficiency on Maintenance of the Hematopoietic Stem Cell Compartment.

Zuzana Tothova, Stephen M Sykes, Dena S Leeman, James W Horner, Norman Sharpless, Ronald A DePinho, D. Gary Gilliland
Journal: Blood
Blood (2008) 112 (11): 1405.
https://doi.org/10.1182/blood.V112.11.1405.1405
Published: 2008
Journal Articles

K-Ras G12D –induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to γ-secretase inhibitors

Thomas Kindler, Melanie G. Cornejo, Claudia Scholl, Jianing Liu, Dena S. Leeman, J. Erika Haydu, Stefan Fröhling, Benjamin H. Lee, D. Gary Gilliland
Journal: Blood
Blood (2008) 112 (8): 3373–3382.
https://doi.org/10.1182/blood-2008-03-147587
Published: 2008
Journal Articles

Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-Induced Polycythemia Vera.

Gerlinde Wernig, MD, Michael G. Kharas, PhD, Rachel Okabe, Sandra A. Moore, Dena S. Leeman, Dana E. Cullen, Maricel Gozo, Elizabeth P. McDowell, Ross L. Levine, John Doukas, Chi Ching Mak, Glenn Noronha, Michael Martin, Yon D. Ko, Benjamin H. Lee, Richard Soll, Ayalew Tefferi, John D. Hood, D. Gary Gilliland
Journal: Blood
Blood (2007) 110 (11): 556.
https://doi.org/10.1182/blood.V110.11.556.556
Published: 2007