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Dennis E. Discher
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Journal Articles

The reason sickle reticulocytes expose PS

Dennis E. Discher, Paul A. Ney
Journal: Blood
Blood (2015) 126 (15): 1737–1738.
https://doi.org/10.1182/blood-2015-08-665117
Published: 2015
Journal Articles

Cell rigidity and shape override CD47’s “self”-signaling in phagocytosis by hyperactivating myosin-II

Nisha G. Sosale, Tahereh Rouhiparkouhi, Andrew M. Bradshaw, Rumiana Dimova, Reinhard Lipowsky, Dennis E. Discher
Journal: Blood
Blood (2015) 125 (3): 542–552.
https://doi.org/10.1182/blood-2014-06-585299
Published: 2015
Includes: Supplemental data
Journal Articles

Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia

Kyle R. Spinler, Jae-Won Shin, Michele P. Lambert, Dennis E. Discher
Journal: Blood
Blood (2015) 125 (3): 525–533.
https://doi.org/10.1182/blood-2014-05-576462
Published: 2015
Includes: Supplemental data
Journal Articles

Platelet-Like-Particles Sheared From Myosin-II-Inhibited Megakaryocytes Highlights The Elevated Thrombocrit Of May-Hegglin Anomaly

Kyle R Spinler, B.S., Jae-Won Shin, Ph.D., Dennis E Discher, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 2426.
https://doi.org/10.1182/blood.V122.21.2426.2426
Published: 2013
Journal Articles

How Does CD47-SIRPα ‘Don’t Eat Me Signal’ Physically Signal Self

Sosale Nisha, Dennis E. Discher, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 953.
https://doi.org/10.1182/blood.V122.21.953.953
Published: 2013
Journal Articles

Hierarchical Determination of Nuclear Deformability by Lamin Isoforms During Adult Hematopoiesis: Implications in Blood Cell Trafficking

Jae-Won Shin, Ph.D., Kyle R Spinler, B.S., Joe Swift, Ph.D., Dennis E Discher, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 1200.
https://doi.org/10.1182/blood.V120.21.1200.1200
Published: 2012
Journal Articles

Shear-Optimized Platelet-Like-Particles From High Ploidy Mks: From Segregation to Composition and Activation

Kyle R Spinler, B.S., Jae-Won Shin, Ph.D., Dennis E Discher, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 3456.
https://doi.org/10.1182/blood.V120.21.3456.3456
Published: 2012
Journal Articles

RhoA Is Essential for Maintaining Normal Megakaryocyte Ploidy Distribution and Platelet Generation

Aae Suzuki, Jae-Won Shin, Ph.D., Yuhuan Wang, PhD, Mortimer Poncz, MD, John K. Choi, MD, PhD, Dennis E Discher, Ph.D., Christopher L. Carpenter, MD, PhD, Lurong Lian, Liang Zhao, Ph.D., Yanfeng Wang, Charles S. Abrams, MD
Journal: Blood
Blood (2012) 120 (21): 385.
https://doi.org/10.1182/blood.V120.21.385.385
Published: 2012
Journal Articles

Marker-of-self becomes marker-of-senescence

Nisha Sosale, Dennis E. Discher
Journal: Blood
Blood (2012) 119 (23): 5343–5344.
https://doi.org/10.1182/blood-2012-04-418608
Published: 2012
Journal Articles

Myosin-II Is a Major Modulator of Human Hematopoietic Stem Cell Proliferation and Differentiation

Jae-Won Shin, B.S., Amnon Buxboim, Ph.D., Dennis E Discher, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 2343.
https://doi.org/10.1182/blood.V118.21.2343.2343
Published: 2011
Journal Articles

Platelet Generation Under Shear Force Is Modulated by Site-Specific Phosphorylation of Myosin-II Heavy Chain,

Kyle R Spinler, B.S., Jae-Won Shin, B.S., Dennis E Discher, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 3262.
https://doi.org/10.1182/blood.V118.21.3262.3262
Published: 2011
Journal Articles

Myosin-II Plays Central Roles In Cell Life and Death Decisions During Adult Hematopoiesis.

Jae-Won Shin, B.S., Kyle R Spinler, B.S., Joe Swift, Ph.D., Dennis E Discher, Ph.D.
Journal: Blood
Blood (2010) 116 (21): 1595.
https://doi.org/10.1182/blood.V116.21.1595.1595
Published: 2010
Journal Articles

Multiscale Mechanics of Fibrin Clots

Andre E.X. Brown, Rustem I. Litvinov, M.D., Prashant Purohit, Dennis E. Discher, John Weisel
Journal: Blood
Blood (2008) 112 (11): 3089.
https://doi.org/10.1182/blood.V112.11.3089.3089
Published: 2008
Journal Articles

Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding

Colin P. Johnson, Massimiliano Gaetani, Vanessa Ortiz, Nishant Bhasin, Sandy Harper, Patrick G. Gallagher, David W. Speicher, Dennis E. Discher
Journal: Blood
Blood (2006) 109 (8): 3538–3543.
https://doi.org/10.1182/blood-2006-07-038588
Published: 2006
Includes: Supplemental data
Journal Articles

Species- and cell type-specific interactions between CD47 and human SIRPα

Shyamsundar Subramanian, Ranganath Parthasarathy, Shamik Sen, Eric T. Boder, Dennis E. Discher
Journal: Blood
Blood (2006) 107 (6): 2548–2556.
https://doi.org/10.1182/blood-2005-04-1463
Published: 2006
Includes: Supplemental data
Journal Articles

Protein 4.2 is critical to CD47-membrane skeleton attachment in human red cells

Kris Noel Dahl, Ranganath Parthasarathy, Connie M. Westhoff, D. Mark Layton, Dennis E. Discher
Journal: Blood
Blood (2004) 103 (3): 1131–1136.
https://doi.org/10.1182/blood-2003-04-1331
Published: 2004
Journal Articles

Fractional attachment of CD47 (IAP) to the erythrocyte cytoskeleton and visual colocalization with Rh protein complexes

Kris Noel Dahl, Connie M. Westhoff, Dennis E. Discher
Journal: Blood
Blood (2003) 101 (3): 1194–1199.
https://doi.org/10.1182/blood-2002-04-1187
Published: 2003