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Dorette Van Ingen Schenau
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Journal Articles

TP53 Aberrant B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Are Uniquely Sensitive to a Combination of Pyrimidine De Novo Synthesis Blockade and Replication Checkpoint Inhibition

Gawin R. Stoll, Dorette Van Ingen Schenau, Willem P. J. Cox, Ziqin Tang, Emmely M. Wagener, Laurens T. van der Meer, Frank N. van Leeuwen
Journal: Blood
Blood (2023) 142 (Supplement 1): 4189.
https://doi.org/10.1182/blood-2023-179159
Published: 2023
Journal Articles

IKZF1 Deletions Induce Resistance to AraC in BCP-ALL Reversible By CDK8/19 Inhibition

Britt M T Vervoort, Miriam Butler, Dorette van Ingen Schenau, Vincent H.J. van der Velden, Beat Bornhauser, Jean-Pierre Bourquin, Laurens T van der Meer, Frank N van Leeuwen
Journal: Blood
Blood (2022) 140 (Supplement 1): 3465–3466.
https://doi.org/10.1182/blood-2022-162246
Published: 2022
Journal Articles

Methionine Restriction As a Novel Therapeutic Strategy for MLL ( KMT2A) -Rearranged Acute Lymphoblastic Leukemia

Trisha Tee, Titine Ruiter, Ahmed Dahaoui, Dorette van Ingen Schenau, Rico Hagelaar, Laurens van der Meer, Frank van Leeuwen
Journal: Blood
Blood (2021) 138 (Supplement 1): 2269.
https://doi.org/10.1182/blood-2021-145308
Published: 2021
Journal Articles

Glucocorticoid Resistance in IKZF1-Deleted BCP-ALL: It Is PTEN Again

Laurens Van Der Meer, PhD, Rene Marke, MSc, Miriam Butler, MSc, Dorette van Ingen Schenau, MSc, Blanca Scheijen, PhD, Frank van Leeuwen, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4088.
https://doi.org/10.1182/blood-2018-99-112888
Published: 2018
Journal Articles

Tumor Suppressors BTG1 and IKZF1 Cooperate during Mouse Leukemia Development and Impact Relapse Rate in Childhood Acute Lymphoblastic Leukemia

Blanca Scheijen, PhD, Esther Tijchon, Dorette van Ingen Schenau, Rene Marke, Liesbeth van Emst, Laurens T Van Der Meer, PhD, Roland P Kuiper, PhD, Judith M. Boer, PhD, Rob Pieters, MD PhD, Peter M Hoogerbrugge, MD PhD, Monique L. Den Boer, PhD, Frank N van Leeuwen, PhD
Journal: Blood
Blood (2015) 126 (23): 905.
https://doi.org/10.1182/blood.V126.23.905.905
Published: 2015
Journal Articles

Cathepsin B Mediated Lysosomal Degradation in Macrophages Controls the Pharmacokinetics of the Therapeutic Protein Asparaginase

Laurens T Van Der Meer, PhD, Samantha YA Terry, PhD, Dorette van Ingen Schenau, MSc, Kiki Andree, MSc, Gerben M Franssen, BSc, Debbie Roeleveld, MSc, Bart Metselaar, PhD, Thomas Reinheckel, PhD, Peter M Hoogerbrugge, MD PhD, Otto C Boerman, PhD, Frank N van Leeuwen, PhD
Journal: Blood
Blood (2015) 126 (23): 3768.
https://doi.org/10.1182/blood.V126.23.3768.3768
Published: 2015
Journal Articles

Tumor Suppressors Btg1 and Btg2 Regulate B Lineage Commitment through Modulation of Ebf1 Activity

Esther Tijchon, MSc, Liesbeth van Emst, Bsc, Dorette van Ingen Schenau, MSc, Laurensia Yuniati, MSc, Jorn Havinga, MSc, Felice Tirone, PhD, Jean-Pierre Rouault, PhD, Peter M Hoogerbrugge, MD PhD, Frank N. van Leeuwen, PhD, Blanca Scheijen, PhD
Journal: Blood
Blood (2014) 124 (21): 4311.
https://doi.org/10.1182/blood.V124.21.4311.4311
Published: 2014
Journal Articles

Btg1-Deficiency Promotes ETV6-RUNX1-Mediated Leukemic Transformation By Upregulation of BCL6

Esther Tijchon, MSc, Liesbeth van Emst, Bsc, Dorette van Ingen Schenau, MSc, Laurens T van der Meer, PhD, Simone de Rijk, BSc, Owen Williams, PhD, Peter M Hoogerbrugge, MD PhD, Blanca Scheijen, PhD, Frank N. van Leeuwen, PhD
Journal: Blood
Blood (2014) 124 (21): 5193.
https://doi.org/10.1182/blood.V124.21.5193.5193
Published: 2014
Journal Articles

Loss Of BTG1 Function Promotes ETV6-RUNX1 -Mediated Leukemic Transformation

Esther J.H. Tijchon, MSc, Liesbeth van Emst, BSc, Dorette van Ingen Schenau, Msc, Laurens T. van der Meer, PhD, Owen Williams, PhD, Peter M. Hoogerbrugge, Blanca Scheijen, PhD, Frank N. van Leeuwen, PhD
Journal: Blood
Blood (2013) 122 (21): 2545.
https://doi.org/10.1182/blood.V122.21.2545.2545
Published: 2013
Journal Articles

Loss Of IKZF1 Function Mediates Resistance Towards Glucocorticoid-Induced Apoptosis

Jorn Havinga, MSc, Laurensia Yuniati, MSc, Marc Demkes, BSc, Dorette van Ingen Schenau, Msc, Roland P. Kuiper, PhD, Peter M. Hoogerbrugge, Frank N. van Leeuwen, PhD, Blanca Scheijen, PhD
Journal: Blood
Blood (2013) 122 (21): 3865.
https://doi.org/10.1182/blood.V122.21.3865.3865
Published: 2013