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Engy Shokry
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Journal Articles

NADPH controls a cell state vulnerability towards ferroptosis in acute lymphoblastic leukaemia

Free
Nikolai Gajic, Rhona Christie, Jordan Martin, Jonathan Josephs-Spaulding, Shirley Lam, Tobias Ackermann, Karen Dunn, Engy Shokry, Alejandro Huerta Uribe, Julie Irving, Frederick van Delft, Freya de Muyer, Panagiotis Ntziachristos, Johan Vande Voorde, David Sumpton, Saverio Tardito, Andrew Brown, Stephen Tait, Chris Halsey
Journal: Blood
Blood (2025) 146 (Supplement 1): 144.
https://doi.org/10.1182/blood-2025-144
Published: 2025
Journal Articles

Selenocysteine dependency renders central nervous system leukaemia therapeutically sensitive to ferroptosis

Free
Nikolai Gajic, Rhona Christie, Shirley Lam, Tobias Ackermann, Ekaterini Himonas, Jonathan Josephs-Spaulding, Anand Manoharan, Victoria Assmann, Jordan Martin, Alexander Collings, Karen Dunn, Engy Shokry, Alejandro Huerta Uribe, Sharon Burns, David O'Connor, Marc Mansour, David Sumpton, G. Vignir Helgason, Johan Vande Voorde, Saverio Tardito, Stephen Tait, Chris Halsey
Journal: Blood
Blood (2025) 146 (Supplement 1): 1526.
https://doi.org/10.1182/blood-2025-1526
Published: 2025
Journal Articles

Nutrient-Sensitising Drug Repurposing Screen Identifies Lomerizine As a Mitochondrial Metabolism Inhibitor in Chronic Myeloid Leukaemia

Free
Ahmed Khalaf, Lucie de Beauchamp, Eric Kalkman, Kevin Rattigan, Ekaterini Himonas, Joe Jones, Daniel James, Engy Shokry Abd Shokry, Mary Scott, Karen Dunn, Saverio Tardito, Mhairi Copland, David Sumpton, Emma Shanks, Vignir Helgason
Journal: Blood
Blood (2023) 142 (Supplement 1): 862.
https://doi.org/10.1182/blood-2023-186405
Published: 2023