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Journal Articles

A Methodologically Updated De-Novo Extraction of Copy Number Signatures in Multiple Myeloma: Clinical Significance and Putative Aetiologies

Andrea Poletti, Stafano Delle Vedove, Gaia Mazzocchetti, Vincenza Solli, Ajsi Kanapari, Enrica Borsi, Marina Martello, Giovanni Martinelli, Silvia Armuzzi, Ilaria Vigliotta, Barbara Taurisano, Ignazia Pistis, Elena Zamagni, Michele Cavo, Carolina Terragna
Journal: Blood
Blood (2022) 140 (Supplement 1): 1559–1560.
https://doi.org/10.1182/blood-2022-164822
Published: 2022
Journal Articles

Negative Selective Pressure Exerted By Maintenance Therapy Promotes the Extinction of Sub-Clones Carrying High-Risk Lesions in Multiple Myeloma

Carolina Terragna, Andrea Poletti, Vincenza Solli, Marina Martello, Enrica Borsi, Lucia Pantani, Agboyi Lakpo, Luca Cifarelli, Silvia Armuzzi, Rosalinda Termini, Elena Zamagni, MD, Paola Tacchetti, Serena Rocchi, Katia Mancuso, Serena Rocchi, Ilaria Rizzello, Giulia Marzocchi, Nicoletta Testoni, Luca Dozza, Maria Teresa Petrucci, Anna Marina Liberati, Giuseppe Rossi, Mario Boccadoro, Michele Cavo
Journal: Blood
Blood (2019) 134 (Supplement_1): 1778.
https://doi.org/10.1182/blood-2019-127799
Published: 2019
Journal Articles

Inter-Cell Networking Profiling Enables Comprehensive Characterization of Immune-Mediated Activity of Anti-CD38 Therapy through Ex-Vivo Analysis of Multiple Myeloma Patients

Alice Bettelli, MS, Rita Ruggiano, Silvia Bocchi, Laura Rocchi, PhD, Andrea Faenza, PhD, Enrica Borsi, Carolina Terragna, Elena Zamagni, MD, Marina Martello, Marco Bettelli, Laura Rambelli, Viviana Guadagnuolo, Nicola Pecorari, Luca Giulianelli, Matteo Pisani, Dario Biscarini, Michele Cavo, Roberto Guerrieri, Massimo Bocchi, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3372.
https://doi.org/10.1182/blood-2019-126894
Published: 2019
Journal Articles

A Maturation Index Defines Newly Diagnosed Multiple Myeloma Patients with Advanced Immunophenotypic and Molecular Differentiation Profiles Associated with Poor Prognosis

Marina Martello, Rosalinda Termini, Enrica Borsi, Vincenza Solli, Andrea Poletti, Luca Cifarelli, Lakpo Agboyi, Silvia Armuzzi, Lucia Pantani, Serena Rocchi, Katia Mancuso, Elena Zamagni, MD, Paola Tacchetti, Mario Arpinati, MD PhD, Gabriella Chirumbolo, Antonella Orlando, Giulia Marzocchi, Nicoletta Testoni, Pier Luigi Luigi Zinzani, MD, Michele Cavo, Carolina Terragna
Journal: Blood
Blood (2019) 134 (Supplement_1): 1797.
https://doi.org/10.1182/blood-2019-129975
Published: 2019
Journal Articles

The Pliancy of Plasma Cell Differentiation Status Conceals a Gradient of Chromosomal Instability in Newly Diagnosed Multiple Myeloma Patients

Marina Martello, Rosalinda Termini, Barbara Santacroce, Enrica Borsi, Vincenza Solli, Andrea Poletti, Chiara Benni, Lucia Pantani, MD, Serena Rocchi, MD, Elena Zamagni, MD, Paola Tacchetti, MD, Beatrice Zannetti, Francesca Ulbar, Mario Arpinati, MD, Gabriella Chirumbolo, Nicoletta Testoni, BSc, Giulia Marzocchi, BSc, PhD, Gaia Ameli, BSc, Giovanni Martinelli, MD, Michele Cavo, MD, Carolina Terragna
Journal: Blood
Blood (2017) 130 (Supplement 1): 1769.
https://doi.org/10.1182/blood.V130.Suppl_1.1769.1769
Published: 2017
Journal Articles

Definition of a Prognostic Risk-Classifier Based on SNPs Array Analysis of Copy Number Alterations in Newly Diagnosed Transplant-Eligible Multiple Myeloma Patients

Carolina Terragna, Vincenza Solli, Andrea Poletti, Barbara Santacroce, Marina Martello, Alessandra Larocca, Luca Dozza, Anna Baraldi, MD, Lucia Pantani, MD, Adelina Sementa, Paola Tacchetti, MD, Norbert Pescosta, MD, Elena Zamagni, MD, Giovanna Leonardi, Caterina Musolino, MD, Giulia Marzocchi, BSc, Letizia Canepa, MD, Gaia Ameli, BSc, Beatrice Zannetti, Anna Pascarella, Enrica Borsi, Luca De Rosa, Nicoletta Testoni, BSc, Giovanni Martinelli, MD, Pieter Sonneveld, MDPhD, Michele Cavo, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3053.
https://doi.org/10.1182/blood.V130.Suppl_1.3053.3053
Published: 2017
Journal Articles

A Branching Evolution Model at Relapse Characterizes Multiple Myeloma Patients Who Responded to up-Front Combination Therapy Including New Drugs

Carolina Terragna, Marina Martello, Barbara Santacroce, Vincenza Solli, Lucia Pantani, Elena Zamagni, Paola Tacchetti, Beatrice Anna Zannetti, Katia Mancuso, Giulia Marzocchi, Nicoletta Testoni, Gaia Ameli, Rosalinda Termini, Flores A Dico, Enrica Borsi, Giovanni Martinelli, Michele Cavo
Journal: Blood
Blood (2016) 128 (22): 2080.
https://doi.org/10.1182/blood.V128.22.2080.2080
Published: 2016
Journal Articles

An Amplicon-Targeted Ultra-Deep Sequencing Approach Reveals the Presence at the Onset of Multiple Myeloma and the Selection over Time of TP53 Sub-Clonal Variants, Which Adversely Influence Patients' Overall Survival

Carolina Terragna, PhD, Marina Martello, PhD, Mauro Procacci, Flavio Mignone, Annalisa Pezzi, PhD, Barbara Santacroce, Lucia Pantani, MD, Igor Saggese, Torsten Haferlach, Elena Zamagni, Enrica Borsi, PhD, Paola Tacchetti, MD, Beatrice A Zannetti, MD, Serena Rocchi, MD, Katia Mancuso, MD, Flores A Dico, Giovanni Martinelli, MD PhD, Michele Cavo
Journal: Blood
Blood (2015) 126 (23): 24.
https://doi.org/10.1182/blood.V126.23.24.24
Published: 2015
Journal Articles

The Alternate Activation of Hedgehog Pathway, Either in CD138+ or in CD138-CD19+ Multiple Myeloma Primary Cells, Impacts on Disease Outcome

Marina Martello, PhD, Daniel Remondini, PhD, Enrica Borsi, PhD, Mauro Procacci, Barbara Santacroce, Annalisa Pezzi, PhD, Angela Flores Dico, Elena Zamagni, Paola Tacchetti, MD, Lucia Pantani, MD, Giulia Marzocchi, PhD, Giovanni Martinelli, MD PhD, Michele Cavo, Carolina Terragna, PhD
Journal: Blood
Blood (2015) 126 (23): 2961.
https://doi.org/10.1182/blood.V126.23.2961.2961
Published: 2015
Journal Articles

High-Throughput Molecular Profiling of Multiple Myeloma (MM) Clonotypic CD19+ B Cells Highlights Pathways Potentially Involved in the Disease Endurance

Marina Martello, PhD, Angela Flores Dico, Daniel Remondini, PhD, Giovanni Martinelli, MD, Enrica Borsi, PhD, Barbara Santacroce, Lucia Pantani, MD, Elena Zamagni, MD, Paola Tacchetti, MD, Annamaria Brioli, MD, Anna Beatrice Zannetti, MD, Katia Mancuso, MD, Serena Rocchi, MD, Annalisa Pezzi, Statistician, Nicoletta Testoni, PhD, Giulia Marzocchi, PhD, Gaia Ameli, Michele Cavo, MD, Carolina Terragna, PhD
Journal: Blood
Blood (2014) 124 (21): 2054.
https://doi.org/10.1182/blood.V124.21.2054.2054
Published: 2014
Journal Articles

A Long Tail of Sub-Clonal TP53 Mutations Emerged By Ultra-Deep Sequencing of Newly Diagnosed Multiple Myeloma (MM)

Marina Martello, PhD, Barbara Santacroce, Angela Flores Dico, Enrica Borsi, PhD, Torsten Haferlach, Flavio Mignone, Igor Saggese, Elena Zamagni, MD, Paola Tacchetti, MD, Lucia Pantani, MD, Annamaria Brioli, MD, Beatrice Anna Zannetti, MD, Serena Rocchi, MD, Katia Mancuso, MD, Nicoletta Testoni, BSc, Giulia Marzocchi, PhD, Gaia Ameli, BSc, Annalisa Pezzi, Michele Cavo, MD, Giovanni Martinelli, MD, Carolina Terragna, PhD
Journal: Blood
Blood (2014) 124 (21): 3400.
https://doi.org/10.1182/blood.V124.21.3400.3400
Published: 2014
Journal Articles

Virtual Karyotype Reconstruction By SNPs Array of Newly Diagnosed Multiple Myeloma (MM) Patients Enrolled in the EMN02 Clinical Trial

Carolina Terragna, PhD, Angela Flores Dico, Marina Martello, PhD, Vincenzo Callea, MD, Gioacchino Catania, MD, Tonino Spadano, MD, Tommaso Caravita di Toritto, Nicoletta Testoni, BSc, Anders Waage, MD PhD, Enrica Borsi, PhD, Antonio Palumbo, MD, Sonja Zweegman, MD PhD, Annamaria Cafro, MD, Angelo D. Palmas, MD, Silvestro Volpe, MD, Marcella Prete, MD, Ernesto Vigna, MD, Luca De Rosa, MD, Claudia Cellini, MD, Pieter Sonneveld, MD, Michele Cavo, MD
Journal: Blood
Blood (2014) 124 (21): 2033.
https://doi.org/10.1182/blood.V124.21.2033.2033
Published: 2014
Journal Articles

Impact Of p53 Impaired Function On Outcomes Of Multiple Myeloma Patients Carrying Deleted TP53 and/Or Amplified MDM4

Carolina Terragna, PhD, Marina Martello, Enrica Borsi, PhD, Lucia Pantani, MD, Elena Zamagni, MD, Paola Tacchetti, MD, Brioli Annamaria, MD, Beatrice Anna Zannetti, MD, Flores Dico, Nicoletta Testoni, BS, Giulia Marzocchi, PhD, Katia Mancuso, MD, Serena Rocchi, MD, Giovanni Martinelli, MD, Michele Cavo, MD
Journal: Blood
Blood (2013) 122 (21): 1855.
https://doi.org/10.1182/blood.V122.21.1855.1855
Published: 2013
Journal Articles

SIRT Regulates the Molecular Interaction Between c-MYC and HIF-1α in Multiple Myeloma

Enrica Borsi, Giulia Perrone, MD, Carolina Terragna, PhD, Marina Martello, Manuela Mancini, PhD, Elisa Leo, PhD, Elena Zamagni, MD, Paola Tacchetti, MD, Annamaria Brioli, MD, Lucia Pantani, MD, Beatrice Anna Zannetti, MD, Giovanni Martinelli, MD, Michele Cavo, MD
Journal: Blood
Blood (2012) 120 (21): 574.
https://doi.org/10.1182/blood.V120.21.574.574
Published: 2012
Journal Articles

The Poor Outcome of Multiple Myeloma (MM) Patients Carrying At Diagnosis Deleted TP53 and or Amplified MDM4 Might Be Related to the Deregulation of Genes Involved in Cell Cycle Control and DNA Damage Repair

Carolina Terragna, PhD, Marina Martello, Nicoletta Testoni, Emanuele Angelucci, Annamaria Brioli, Stelvio Ballanti, Laura Dessanti, Valerio De Stefano, Gioacchino Catania, Jacopo Peccatori, Luca Castagna, Salvatore Palmieri, Giulia Perrone, Vincenzo Callea, Catello Califano, Anna Baraldi, Enrica Borsi, Luciana Pasini, Mariella Grasso, Pellegrino Musto, Patrizia Tosi, Giovanni Martinelli, Michele Cavo, MD
Journal: Blood
Blood (2012) 120 (21): 1810.
https://doi.org/10.1182/blood.V120.21.1810.1810
Published: 2012
Journal Articles

High Number of Copy Number Alterations and Over-Expression of Genes Involved in the Response Mechanisms to Genotoxic Stress Both Characterize Newly Diagnosed Multiple Myeloma (MM) Patients Carrying Amplified MDM4 and/or Deleted p53 ,

Carolina Terragna, PhD, Marina Martello, Sandra Durante, Lucia Pantani, MD, Elena Zamagni, MD, Paola Tacchetti, MD, Annamaria Brioli, MD, Giulia Perrone, MD, Beatrice Anna Zannetti, MD, Enrica Borsi, PhD, Michele Baccarani, MD, Giovanni Martinelli, MD, Michele Cavo, MD
Journal: Blood
Blood (2011) 118 (21): 3935.
https://doi.org/10.1182/blood.V118.21.3935.3935
Published: 2011
Journal Articles

HIF 1 Alpha: A Suitable Target for Multiple Myeloma

Giulia Perrone, MD, Enrica Borsi, PhD, Carolina Terragna, PhD, Sandra Durante, Marina Martello, Michela Aluigi, PhD, Manuela Mancini, PhD, Elena Zamagni, MD, Paola Tacchetti, MD, Annamaria Brioli, MD, Lucia Pantani, MD, Beatrice Anna Zannetti, MD, Giovanni Martinelli, MD, Maria Alessandra Santucci, MD, Michele Baccarani, MD, Michele Cavo, MD
Journal: Blood
Blood (2011) 118 (21): 2901.
https://doi.org/10.1182/blood.V118.21.2901.2901
Published: 2011