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Journal Articles

Chromosome 9p Duplication Promotes T-Cell Exhaustion and Enhances Stem Cell Clonogenic Potential in JAK2-Mutant Myeloproliferative Neoplasms

Blood (2023) 142 (Supplement 1): 1780.

https://doi.org/10.1182/blood-2023-182420

Published: 2023

Journal Articles

Peripheral Blood Cytotoxic T Cells from Myelofibrosis Patients Show Early Exhausted Features Targetable By CTLA-4 Inhibition

Lara Tavernari, Sebastiano Rontauroli, Monica Maccaferri, Barbara Mora, Elia Venturelli, Elisa Bianchi, Sandra Parenti, Elena Genovese, Paola Guglielmelli, Chiara Carretta, Margherita Mirabile, Stefano Sartini, Corrado Colasante, Leonardo Potenza, Francesco Passamonti, Enrico Tagliafico, Mario Luppi, Alessandro M. Vannucchi, Rossella Manfredini

Blood (2022) 140 (Supplement 1): 9600–9601.

https://doi.org/10.1182/blood-2022-167161

Published: 2022

Journal Articles

Calreticulin Ins5 and Del52 Mutations Impair Unfolded Protein and Oxidative Stress Responses in Hematopoietic Cells

Simona Salati, PhD, Elena Genovese, BSc, Zelia Prudente, BSc, PhD, Chiara Carretta, Niccolò Bartalucci, PhD BSc, Valentina Pennucci, PhD, Samantha Ruberti, BSc, PhD, Chiara Rossi, PharmD, Sebastiano Rontauroli, BSc, Carmela Mannarelli, PhD, Roberta Zini, BSc, PhD, Elisa Bianchi, BSc, PhD, Paola Guglielmelli, MD PhD, Enrico Tagliafico, MDPhD, Alessandro M. Vannucchi, MD, Rossella Manfredini, PhD

Blood (2018) 132 (Supplement 1): 4332.

https://doi.org/10.1182/blood-2018-99-112550

Published: 2018

Journal Articles

The Role of the Axis TGF-β1/Mir-382-5p/SOD2 in the Induction of Oxidative Stress in CD34+ Hematopoietic Stem/Progenitor Cells from Primary Myelofibrosis

Chiara Rossi, PharmD, Roberta Zini, BSc, PhD, Samantha Ruberti, BSc, PhD, Sebastiano Rontauroli, BSc, Zelia Prudente, BSc, PhD, Greta Barbieri, BSc, Elisa Bianchi, BSc, PhD, Simona Salati, BSc, PhD, Elena Genovese, BSc, Carmela Mannarelli, MSc, PhD, Paola Guglielmelli, MD PhD, Enrico Tagliafico, MDPhD, Vittorio Rosti, MD, Giovanni Barosi, MD, Alessandro M. Vannucchi, Rossella Manfredini, BSc, PhD

Blood (2017) 130 (Supplement 1): 1655.

https://doi.org/10.1182/blood.V130.Suppl_1.1655.1655

Published: 2017

Journal Articles

MiR-494-3p Overexpression Leads to SOCS6 Downregulation and Supports Megakaryocytopoiesis in Primary Myelofibrosis CD34+ Hematopoietic Stem/Progenitor Cells

Sebastiano Rontauroli, BSc, Ruggiero Norfo, PhD, Valentina Pennucci, PhD, Roberta Zini, PhD, Samantha Ruberti, BSc, Elisa Bianchi, PhD, Simona Salati, PhD, Zelia Prudente, PhD, Chiara Rossi, BSc, Vittorio Rosti, Paola Guglielmelli, MD PhD, Giovanni Barosi, Alessandro M. Vannucchi, MD, Enrico Tagliafico, MD PhD, Rossella Manfredini, PhDBSc

Blood (2016) 128 (22): 4272.

https://doi.org/10.1182/blood.V128.22.4272.4272

Published: 2016

Journal Articles

MAF Induces Inflammatory Mediators Involved in the Pathogenesis of Primary Myelofibrosis

Samantha Ruberti, BSc, Elisa Bianchi, PhD, Tiziana Fanelli, MSc, Sebastiano Rontauroli, BSc, Valentina Pennucci, PhD, Giuditta Corbizzi Fattori, BSc, Carmela Mannarelli, MSc, PhD, Ruggiero Norfo, PhD, Chiara Rossi, BSc, Roberta Zini, PhD, Simona Salati, PhD, Zelia Prudente, PhD, Enrico Tagliafico, MDPhD, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi, MD, Rossella Manfredini, PhDBSc

Blood (2016) 128 (22): 3132.

https://doi.org/10.1182/blood.V128.22.3132.3132

Published: 2016

Journal Articles

Integrative Analysis of Copy Number and Gene Expression Data Suggests Novel Pathogenetic Mechanisms in Primary Myelofibrosis

Blood (2015) 126 (23): 2830.

https://doi.org/10.1182/blood.V126.23.2830.2830

Published: 2015

Journal Articles

Impact of Mutation Status of ASXL1, EZH2, SRSF2, IDH1/2 on Clinical Phenotype and Prognosis in Patients with Post-Polycythemia and Post-Essential Thrombocythemia Myelofibrosis: An AGIMM Study

Blood (2014) 124 (21): 1867.

https://doi.org/10.1182/blood.V124.21.1867.1867

Published: 2014

Journal Articles

Mutation-Enhanced International Prognostic Scoring System (MIPSS) for Primary Myelofibrosis: An AGIMM & IWG-MRT Project

Blood (2014) 124 (21): 405.

https://doi.org/10.1182/blood.V124.21.405.405

Published: 2014

Journal Articles

miRNA-mRNA integrative analysis in primary myelofibrosis CD34 + cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis

Blood (2014) 124 (13): e21–e32.

https://doi.org/10.1182/blood-2013-12-544197

Published: 2014

Includes: Supplemental data

Journal Articles

Impact of mutational status on outcomes in myelofibrosis patients treated with ruxolitinib in the COMFORT-II study

Paola Guglielmelli, Flavia Biamonte, Giada Rotunno, Valentina Artusi, Lucia Artuso, Isabella Bernardis, Elena Tenedini, Lisa Pieri, Chiara Paoli, Carmela Mannarelli, Rajmonda Fjerza, Elisa Rumi, Viktoriya Stalbovskaya, Matthew Squires, Mario Cazzola, Rossella Manfredini, Claire Harrison, Enrico Tagliafico, Alessandro M. Vannucchi

Blood (2014) 123 (14): 2157–2160.

https://doi.org/10.1182/blood-2013-11-536557

Published: 2014

Includes: Supplemental data

Journal Articles

Abnormal Expression Of WT1-As, MEG3 and ANRIL Long Non-Coding RNAs In Primary Myelofibrosis and Their Clinical Correlates

Blood (2013) 122 (21): 2845.

https://doi.org/10.1182/blood.V122.21.2845.2845

Published: 2013

Journal Articles

Integrative Analysis Of mRNA/miRNA Expression Profiles Identified JARID2 As a Shared Target Of Deregulated Mirnas In Primary Myelofibrosis

Blood (2013) 122 (21): 1600.

https://doi.org/10.1182/blood.V122.21.1600.1600

Published: 2013

Journal Articles

Targeted Cancer Exome Sequencing Discovers Novel Recurrent Mutations In MPN

Elena Tenedini, PhD, Isabella Bernardis, MSc, Valentina Artusi, MSc, Lucia Artuso, PhD, Enrica Roncaglia, PhD, Paola Guglielmelli, PhD MD, Lisa Pieri, PhD MD, Costanza Bogani, PhD, Flavia Biamonte, BiSci, PhD, Elisa Bianchi, PhD, Alessandro Pancrazzi, BiSci, Carmela Mannarelli, BiSci, Tiziana Fanelli, BiSci, Giada Rotunno, BiSci, Guidantonio Malagoli Tagliazucchi, MSc, Sergio Ferrari, MD, Rossella Manfredini, PhD, Alessandro M Vannucchi, MD, Enrico Tagliafico, MD PhD

Blood (2013) 122 (21): 4099.

https://doi.org/10.1182/blood.V122.21.4099.4099

Published: 2013

Journal Articles

Impact Of Prognostically Detrimental Mutations ( ASXL1, EZH2, SRSF2, IDH1/2 ) On Outcomes In Patients With Myelofibrosis Treated With Ruxolitinib In COMFORT-II

Paola Guglielmelli, PhD MD, Flavia Biamonte, BiSci, PhD, Lisa Pieri, MD PhD, Giada Rotunno, BiSci, Chiara Paoli, BiSci, Rajmonda Fjerza, MD, Enrico Tagliafico, MD PhD, Rossella Manfredini, PhD, Valentina Artusi, MSc, Elena Tenedini, PhD, Lucia Artuso, PhD, Isabella Bernardis, Viktoriya Stalbovskaya, PhD, Matthew Squires, PhD, Claire N Harrison, DM, FRCP, FRCPath, Alessandro M Vannucchi, MD

Blood (2013) 122 (21): 107.

https://doi.org/10.1182/blood.V122.21.107.107

Published: 2013

Journal Articles

The Interlaboratory Robustness of Next-Generation Sequencing (IRON) Study Phase II: Deep-Sequencing Analyses of Hematological Malignancies Performed by an International Network Involving 26 Laboratories

Blood (2012) 120 (21): 1399.

https://doi.org/10.1182/blood.V120.21.1399.1399

Published: 2012

Journal Articles

Regulatory Mrna/Microrna Networks in CD34+ Cells From Primary Myelofibrosis.

Blood (2012) 120 (21): 2854.

https://doi.org/10.1182/blood.V120.21.2854.2854

Published: 2012

Journal Articles

c-myb supports erythropoiesis through the transactivation of KLF1 and LMO2 expression

Elisa Bianchi, Roberta Zini, Simona Salati, Elena Tenedini, Ruggiero Norfo, Enrico Tagliafico, Rossella Manfredini, Sergio Ferrari

Blood (2010) 116 (22): e99–e110.

https://doi.org/10.1182/blood-2009-08-238311

Published: 2010

Includes: Supplemental data

Journal Articles

Gene expression profiling of normal and malignant CD34-derived megakaryocytic cells

Elena Tenedini, Maria Elena Fagioli, Nicola Vianelli, Pier Luigi Tazzari, Francesca Ricci, Enrico Tagliafico, Paolo Ricci, Luigi Gugliotta, Giovanni Martinelli, Sante Tura, Michele Baccarani, Sergio Ferrari, Lucia Catani

Blood (2004) 104 (10): 3126–3135.

https://doi.org/10.1182/blood-2003-07-2597

Published: 2004

Includes: Supplemental data

Journal Articles

Antisense Inhibition of c-fes Proto-oncogene Blocks PMA-Induced Macrophage Differentiation in HL60 and in FDC-P1/MAC-11 Cells

Rossella Manfredini, Raffaella Balestri, Enrico Tagliafico, Francesca Trevisan, Michela Pizzanelli, Alexis Grande, Daniela Barbieri, Patrizia Zucchini, Gennaro Citro, Claudio Franceschi, Sergio Ferrari

Blood (1997) 89 (1): 135–145.

https://doi.org/10.1182/blood.V89.1.135

Published: 1997

NARROW

Chromosome 9p Duplication Promotes T-Cell Exhaustion and Enhances Stem Cell Clonogenic Potential in JAK2-Mutant Myeloproliferative Neoplasms

Peripheral Blood Cytotoxic T Cells from Myelofibrosis Patients Show Early Exhausted Features Targetable By CTLA-4 Inhibition

Calreticulin Ins5 and Del52 Mutations Impair Unfolded Protein and Oxidative Stress Responses in Hematopoietic Cells

The Role of the Axis TGF-β1/Mir-382-5p/SOD2 in the Induction of Oxidative Stress in CD34+ Hematopoietic Stem/Progenitor Cells from Primary Myelofibrosis

MiR-494-3p Overexpression Leads to SOCS6 Downregulation and Supports Megakaryocytopoiesis in Primary Myelofibrosis CD34+ Hematopoietic Stem/Progenitor Cells

MAF Induces Inflammatory Mediators Involved in the Pathogenesis of Primary Myelofibrosis

Integrative Analysis of Copy Number and Gene Expression Data Suggests Novel Pathogenetic Mechanisms in Primary Myelofibrosis

Impact of Mutation Status of ASXL1, EZH2, SRSF2, IDH1/2 on Clinical Phenotype and Prognosis in Patients with Post-Polycythemia and Post-Essential Thrombocythemia Myelofibrosis: An AGIMM Study

Mutation-Enhanced International Prognostic Scoring System (MIPSS) for Primary Myelofibrosis: An AGIMM & IWG-MRT Project

miRNA-mRNA integrative analysis in primary myelofibrosis CD34 + cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis

Impact of mutational status on outcomes in myelofibrosis patients treated with ruxolitinib in the COMFORT-II study

Abnormal Expression Of WT1-As, MEG3 and ANRIL Long Non-Coding RNAs In Primary Myelofibrosis and Their Clinical Correlates

Integrative Analysis Of mRNA/miRNA Expression Profiles Identified JARID2 As a Shared Target Of Deregulated Mirnas In Primary Myelofibrosis

Targeted Cancer Exome Sequencing Discovers Novel Recurrent Mutations In MPN

Impact Of Prognostically Detrimental Mutations ( ASXL1, EZH2, SRSF2, IDH1/2 ) On Outcomes In Patients With Myelofibrosis Treated With Ruxolitinib In COMFORT-II

The Interlaboratory Robustness of Next-Generation Sequencing (IRON) Study Phase II: Deep-Sequencing Analyses of Hematological Malignancies Performed by an International Network Involving 26 Laboratories

Regulatory Mrna/Microrna Networks in CD34+ Cells From Primary Myelofibrosis.

c-myb supports erythropoiesis through the transactivation of KLF1 and LMO2 expression

Gene expression profiling of normal and malignant CD34-derived megakaryocytic cells

Antisense Inhibition of c-fes Proto-oncogene Blocks PMA-Induced Macrophage Differentiation in HL60 and in FDC-P1/MAC-11 Cells

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American Society of Hematology

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American Society of Hematology

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