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Journal Articles

Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling

Stanley C Lee, PhD, Khrystyna North, Chi-Chao Chen, Eunhee Kim, PhD, Sydney X. Lu, MD PhD, Michelle Ki, BSc, Ralph Garippa, PhD, Scott W Lowe, PhD, Robert K. Bradley, PhD, Omar I Abdel-Wahab, MD

Blood (2018) 132 (Supplement 1): 937.

https://doi.org/10.1182/blood-2018-99-111552

Published: 2018

Journal Articles

RUNX1 Deficiency Cooperates with SRSF2 Mutation to Further Disrupt RNA Splicing and Exacerbate Myelodysplastic Syndromes in Mouse Models

Yi-Jou Huang, BS, Ming Yan, PhD, Jia-Yu Chen, PhD, Liang Chen, PhD, Eunhee Kim, PhD, Takahiro Shima, MD PhD, Amanda G Davis, BS, Sayuri Miyauchi, DDS, PhD, Samuel A Stoner, Xiang-Dong Fu, PhD, Omar I Abdel-Wahab, MD, Dong-Er Zhang, PhD

Blood (2018) 132 (Supplement 1): 1796.

https://doi.org/10.1182/blood-2018-99-119104

Published: 2018

Journal Articles

RUNX1 Deficiency and SRSF2 Mutation Cooperate to Promote Myelodysplastic Syndrome Development

Yi-Jou Huang, BS, Ming Yan, PhD, Eunhee Kim, PhD, Amanda G Davis, BS, Takahiro Shima, MD PhD, Sayuri Miyauchi, DDS, PhD, Xiang-Dong Fu, PhD, Omar Abdel-Wahab, MD, Dong-Er Zhang, PhD

Blood (2017) 130 (Supplement 1): 119.

https://doi.org/10.1182/blood.V130.Suppl_1.119.119

Published: 2017

Journal Articles

Genomic Analysis of Hairy Cell Leukemia Identifies Novel Recurrent Genetic Alterations

Blood (2017) 130 (Supplement 1): 2994.

https://doi.org/10.1182/blood.V130.Suppl_1.2994.2994

Published: 2017

Journal Articles

Serine/Arginine-Rich Splicing Factor 1 (SRSF1) Is Required for Adult and Embryonic Hematopoiesis and Has Non-Overlapping Roles with SRSF2 in Hematopoiesis

Young Rock Chung, MS, Hana Cho, Young Joon Kim, Eunhee Kim, PhD, Stanley Chun-Wei Lee, PhD, Omar Abdel-Wahab, MD

Blood (2016) 128 (22): 1478.

https://doi.org/10.1182/blood.V128.22.1478.1478

Published: 2016

Journal Articles

Synthetic Lethal Interactions of MDS-Associated Spliceosomal Gene Mutations Identifies the Basis for Their Mutual Exclusivity

Stanley Chun-Wei Lee, PhD, Khrystyna Dilai, Esther A. Obeng, MDPhD, Eunhee Kim, PhD, Jean-Baptiste Micol, MD PhD, Akihide Yoshimi, MD PhD, Christophe Willekens, MD, Daichi Inoue, Véronique Saada, PharmD, Hana Cho, Young Rock Chung, MS, James Palacino, PhD, Michael Seiler, PhD, Silvia Buonamici, PhD, Peter Smith, Benjamin L. Ebert, MD PhD, Robert Bradley, PhD, Omar Abdel-Wahab, MD

Blood (2016) 128 (22): 961.

https://doi.org/10.1182/blood.V128.22.961.961

Published: 2016

Journal Articles

ASXL2 Is a Novel Mediator of RUNX1-ETO Transcriptional Function and Collaborates with RUNX1-ETO to Promote Leukemogenesis

Jean-Baptiste Micol, MD, Nicolas Duployez, Alessandro Pastore, MD, Robert Williams, Eunhee Kim, PhD, Stanley Lee, Benjamin Durham, MD PhD, Young Rock Chung, MS, Hana Cho, Claude Preudhomme, Omar Abdel-Wahab

Blood (2015) 126 (23): 302.

https://doi.org/10.1182/blood.V126.23.302.302

Published: 2015

Journal Articles

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Benjamin Heath Durham, MD BS, Eli L. Diamond, MD, Julien Haroche, MD PhD, Zhan Yao, PhD, Jing Ma, PhD, Sameer A. Parikh, MD, John Choi, Eunhee Kim, PhD, Fleur Cohen-Aubart, Stanley Chun-Wei Lee, Yijun Gao, Jean-Baptiste Micol, MD, Patrick Campbell, MD PhD, Michael P. Walsh, Brooke Sylvester, Igor Dolgalev, Aminova Olga, Adriana Heguy, Paul Zappile, Joy Nakitandwe, BSc,MSc,PhD, James Dalton, BS, David W Ellison, MD, Juvianee Estrada-Veras, Mario Lacouture, William A. Gahl, MD PhD, Phil Stephens, PhD, Vincent A. Miller, MD, Jeffrey Ross, Siraj Ali, Sebastien Héritier, Jean Donadieu, MD PhD, David Solit, MD, David M. Hyman, Jose Baselga, MD PhD, Filip Janku, MDPhD, Barry S. Taylor, PhD, Christopher Y. Park, MD, PhD, Ahmet Dogan, MD PhD, Zahir Amoura, Jean-Francois Emile, Raajit K. Rampal, MD, PhD, Neal Rosen, MD PhD, Tanja A. Gruber, MD PhD, Omar Abdel-Wahab

Blood (2015) 126 (23): 481.

https://doi.org/10.1182/blood.V126.23.481.481

Published: 2015

Journal Articles

Diverse Mechanisms of Vemurafenib Resistance in BRAF-Mutant Hairy Cell Leukemia

Jae H Park, MD, Stephen S. Chung, MD, Benjamin Durham, MD PhD, Young Rock Chung, MS, Sasinya Scott, MPH, Bartlomiej Getta, MBBS,, Eunhee Kim, PhD, Alan Saven, MD, Richard M. Stone, MD, Kanti R Rai, MD, Michael R. Grever, MD, Jessica K. Altman, MD, Neal Rosen, MD PhD, Ross L. Levine, MD, Michael Berger, PhD, Martin S Tallman, MD, Omar Abdel-Wahab

Blood (2015) 126 (23): 449.

https://doi.org/10.1182/blood.V126.23.449.449

Published: 2015

Journal Articles

Therapeutic Targeting of Spliceosomal Mutant Myeloid Leukemias through Modulation of Splicing Catalysis

Stanley Chun-Wei Lee, PhD, Heidi Dvinge, Eunhee Kim, PhD, Hana Cho, Young Rock Chung, MS, Jean-Baptiste Micol, MD, Benjamin Durham, MD PhD, Young Joon Kim, Michael Thomas, Camille Lobry, PhD, Silvia Buonamici, PhD, Peter Smith, Robert K. Bradley, PhD, Omar Abdel-Wahab

Blood (2015) 126 (23): 4.

https://doi.org/10.1182/blood.V126.23.4.4

Published: 2015

Journal Articles

SRSF2 Mutations Impair Hematopoietic Differentiation By Altering Exonic Splicing Enhancer Preference

Eunhee Kim, PhD, Janine O. Ilagan, PhD, Stanley Lee, PhD, Aravind Ramakrishnan, MD, Young Rock Chung, MS, Jean-Baptiste Micol, MD, Michele E. Murphy, Min-Kyung Kim, BS, Ahmad S. Zebari, Jacob Feala, Silvia Buonamici, PhD, Peter G Smith, PhD, H. Joachim Deeg, MD, Camille Lobry, PhD, Iannis Aifantis, PhD MSC, Robert K. Bradley, PhD, Omar Abdel-Wahab, MD

Blood (2014) 124 (21): 824.

https://doi.org/10.1182/blood.V124.21.824.824

Published: 2014

Journal Articles

Unraveling the Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms through Whole Exome Sequencing

Benjamin Durham, MD, Jing Ma, PhD, Eunhee Kim, PhD, John K. Choi, MD, Patrick Campbell, MD PhD, Juvianee Estrada-Veras, MD, Michael P Walsh, PhD, Mario E Lacouture, MD, Young Rock Chung, MS, Joy Nakitandwe, PhD, Eli Diamond, David M. Hyman, MD, Raajit K. Rampal, MD PhD, Minal Patel, Christopher Y. Park, MD PhD, Tanja A. Gruber, MD PhD, Omar Abdel-Wahab, MD

Blood (2014) 124 (21): 1887.

https://doi.org/10.1182/blood.V124.21.1887.1887

Published: 2014

Journal Articles

Vemurafenib Has Potent Antitumor Activity in Patients with Relapsed/Refractory BRAF Mutant Hairy Cell Leukemia

Jae H Park, MD, Stephen S. Chung, MD, Young Rock Chung, MS, Helen Won, MS, Eunhee Kim, PhD, Alan Saven, MD, Martha Wadleigh, MD, Richard M. Stone, MD, Jacqueline C. Barrientos, MD, Kanti R. Rai, MD, Michael R. Grever, MD, Jessica K. Altman, MD, Mario E Lacouture, MD, Neal Rosen, MD PhD, Michael Berger, PhD, Ross L Levine, MD, Omar Abdel-Wahab, MD, Martin S. Tallman, MD

Blood (2014) 124 (21): 24.

https://doi.org/10.1182/blood.V124.21.24.24

Published: 2014

Journal Articles

BRAF V600E Mutations Occur In The Hematopoietic Stem Cell Compartment In Hairy Cell Leukemia

Stephen S. Chung, MD, Jae H. Park, MD, Eunhee Kim, PhD, Young Rock Chung, MSc, Wenhuo Hu, PhD, Piro Lito, MD, PhD, Julie Teruya Feldstein, MD, Raajit K. Rampal, M.D., Ph.D., Leon Telis, Minal Patel, Neal Rosen, Christopher Y. Park, M.D., Ph.D., Martin S. Tallman, MD, Omar Abdel-Wahab, MD

Blood (2013) 122 (21): 816.

https://doi.org/10.1182/blood.V122.21.816.816

Published: 2013

NARROW

Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling

RUNX1 Deficiency Cooperates with SRSF2 Mutation to Further Disrupt RNA Splicing and Exacerbate Myelodysplastic Syndromes in Mouse Models

RUNX1 Deficiency and SRSF2 Mutation Cooperate to Promote Myelodysplastic Syndrome Development

Genomic Analysis of Hairy Cell Leukemia Identifies Novel Recurrent Genetic Alterations

Serine/Arginine-Rich Splicing Factor 1 (SRSF1) Is Required for Adult and Embryonic Hematopoiesis and Has Non-Overlapping Roles with SRSF2 in Hematopoiesis

Synthetic Lethal Interactions of MDS-Associated Spliceosomal Gene Mutations Identifies the Basis for Their Mutual Exclusivity

ASXL2 Is a Novel Mediator of RUNX1-ETO Transcriptional Function and Collaborates with RUNX1-ETO to Promote Leukemogenesis

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Diverse Mechanisms of Vemurafenib Resistance in BRAF-Mutant Hairy Cell Leukemia

Therapeutic Targeting of Spliceosomal Mutant Myeloid Leukemias through Modulation of Splicing Catalysis

SRSF2 Mutations Impair Hematopoietic Differentiation By Altering Exonic Splicing Enhancer Preference

Unraveling the Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms through Whole Exome Sequencing

Vemurafenib Has Potent Antitumor Activity in Patients with Relapsed/Refractory BRAF Mutant Hairy Cell Leukemia

BRAF V600E Mutations Occur In The Hematopoietic Stem Cell Compartment In Hairy Cell Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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