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Fabrizio Benedicenti
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Journal Articles

Circulating hematopoietic stem/progenitor cell subsets contribute to human hematopoietic homeostasis

Pamela Quaranta, Luca Basso-Ricci, Raisa Jofra Hernandez, Guido Pacini, Matteo Maria Naldini, Matteo Barcella, Luca Seffin, Giulia Pais, Giulio Spinozzi, Fabrizio Benedicenti, Carlo Pietrasanta, Jin Gyu Cheong, Andrea Ronchi, Lorenza Pugni, Francesca Dionisio, Ilaria Monti, Stefania Giannelli, Silvia Darin, Federico Fraschetta, Graziano Barera, Francesca Ferrua, Valeria Calbi, Marco Ometti, Raffaella Di Micco, Fabio Mosca, Steven Zvi Josefowicz, Eugenio Montini, Andrea Calabria, Maria Ester Bernardo, Maria Pia Cicalese, Bernhard Gentner, Ivan Merelli, Alessandro Aiuti, Serena Scala
Journal: Blood
Blood (2024) 143 (19): 1937–1952.
https://doi.org/10.1182/blood.2023022666
Published: 2024
Includes: Supplemental data
Journal Articles

Intrathymic AAV delivery results in therapeutic site-specific integration at TCR loci in mice

Andrea Calabria, Carlo Cipriani, Giulio Spinozzi, Laura Rudilosso, Simona Esposito, Fabrizio Benedicenti, Alessandra Albertini, Marie Pouzolles, Mirko Luoni, Serena Giannelli, Vania Broccoli, Mickael Guilbaud, Oumeya Adjali, Naomi Taylor, Valérie S. Zimmermann, Eugenio Montini, Daniela Cesana
Journal: Blood
Blood (2023) 141 (19): 2316–2329.
https://doi.org/10.1182/blood.2022017378
Published: 2023
Includes: Supplemental data
Journal Articles

Unveiling the Biological Role of Peripheral Blood Human Circulating Hematopoietic Stem and Progenitor Cells

Pamela Quaranta, Luca Basso-Ricci, Raisa Jofra Hernández, Matteo Maria Naldini, Matteo Barcella, Guido Pacini, Carlo Pietrasanta, Lorenza Pugni, Giulia Pais, Fabrizio Benedicenti, Francesca Dionisio, Stefania Giannelli, Ilaria Monti, Silvia Darin, Graziano Barera, Francesca Tucci, Francesca Ferrua, Valeria Calbi, Marco Ometti, Bernhard Gentner, Raffaella Di Micco, Eugenio Montini, Andrea Calabria, Ivan Merelli, Fabio Mosca, Maria Ester Bernardo, Maria Pia Cicalese, Alessandro Aiuti, Serena Scala
Journal: Blood
Blood (2022) 140 (Supplement 1): 1977–1978.
https://doi.org/10.1182/blood-2022-163251
Published: 2022
Journal Articles

Adaptive Routes of Hematopoietic Stem Cell Differentiation to Disease Conditions and Age in Gene Therapy Patients

Andrea Calabria, Giulio Spinozzi, Daniela Cesana, Fabrizio Benedicenti, Giulia Pais, Serena Scala, Maria Rosa Lidonnici, Samantha Scaramuzza, Alessandra Albertini, Simona Esposito, Fabiola De Mattia, Daniele Canarutto, Francesca Tucci, Maryam Omrani, Francesca Dionisio, Stefania Giannelli, Sarah Marktel, Valeria Calbi, Francesca Ferrua, Bernhard Gentner, Fabio Ciceri, Luigi Naldini, Giuliana Ferrari, Alessandro Aiuti, Eugenio Montini
Journal: Blood
Blood (2022) 140 (Supplement 1): 1904–1905.
https://doi.org/10.1182/blood-2022-162195
Published: 2022
Journal Articles

Donor-Derived CAR T Cells Engineered with Sleeping Beauty Achieve Anti-Leukemic Activity without Severe Toxicity

Chiara F Magnani, Giuseppe Gaipa, PhD, Federico Lussana, MD, Daniela Belotti, Giuseppe Gritti, MD PhD, Sara Napolitano, MD, Chiara Buracchi, PhD, Gian Maria Borleri, Silvia Zaninelli, Giuliana Rizzuto, Sarah Tettamanti, PhD, Valentina Colombo, Giovanni Cazzaniga, PhD, Benedetta Cabiati, Attilio Rovelli, MD, Ettore Biagi, MD PhD, Stefania Galimberti, PhD, Fabrizio Benedicenti, Eugenio Montini, PhD, Silvia Ferrari, MD, Martino Introna, MD, Adriana Balduzzi, MD, Maria Grazia Valsecchi, PhD, Giuseppe Dastoli, MD, Alessandro Rambaldi, MD, Andrea Biondi, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-141236
Published: 2020
Journal Articles

Donor-Derived CD19 CAR Cytokine Induced Killer (CIK) Cells Engineered with Sleeping Beauty Transposon for Relapsed B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Chiara F Magnani, PhD, Giuseppe Gaipa, PhD, Daniela Belotti, Giada Matera, Sarah Tettamanti, PhD, Benedetta Cabiati, Chiara Buracchi, PhD, Grazia Fazio, Silvia Zaninelli, Silvia Rigamonti, Stefania Cesana, Valentina Colombo, Giovanni Cazzaniga, PhD, Attilio Rovelli, MD, Adriana Balduzzi, MD, Sara Napolitano, MD, Fabrizio Benedicenti, Eugenio Montini, PhD, Gian Maria Borleri, Silvia Ferrari, MD, Giuseppe Gritti, MD PhD, Federico Lussana, MD, Martino Introna, MD, Alessandro Rambaldi, MD, Giuseppe Dastoli, MD, Andrea Biondi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 200.
https://doi.org/10.1182/blood-2019-125894
Published: 2019
Journal Articles

Sleeping Beauty Modified CAR+ Lymphocytes Engraft and Exhibit Anti-Tumor Activity in Patient-Derived Xenograft Models of Acute Lymphoblastic Leukemia

Chiara F. Magnani, PhD, Claudia Mezzanotte, Claudia Cappuzzello, PhD, Fabrizio Benedicenti, Michela Bardini, PhD, Sarah Tettamanti, PhD, Grazia Fazio, PhD, Gianni Cazzaniga, PhD, Laurence J.N. Cooper, MD PhD, Eugenio Montini, PhD, Andrea Biondi, MD, Ettore Biagi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4022.
https://doi.org/10.1182/blood.V128.22.4022.4022
Published: 2016
Journal Articles

Stable Expression Of Chimeric Antigen Receptors (CARs) By Sleeping Beauty-Mediated Gene Transfer and Efficient Expansion Of Leukemia-Specific Cytokine-Induced Killer (CIK) Cells

Chiara Francesca Magnani, PhD, Nice Turazzi, Fabrizio Benedicenti, Greta Maria Paola Giordano Attianese, PhD, Sarah Tettamanti, PhD, Eugenio Montini, PhD, Laurence J N Cooper, MD, PhD, Alessandro Aiuti, MD, PhD, Andrea Biondi, MD, Ettore Biagi, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1663.
https://doi.org/10.1182/blood.V122.21.1663.1663
Published: 2013
Journal Articles

Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection

Alessandra Biffi, Cynthia C. Bartolomae, Daniela Cesana, Natalie Cartier, Patrik Aubourg, Marco Ranzani, Martina Cesani, Fabrizio Benedicenti, Tiziana Plati, Enrico Rubagotti, Stefania Merella, Alessia Capotondo, Jacopo Sgualdino, Gianluigi Zanetti, Christof von Kalle, Manfred Schmidt, Luigi Naldini, Eugenio Montini
Journal: Blood
Blood (2011) 117 (20): 5332–5339.
https://doi.org/10.1182/blood-2010-09-306761
Published: 2011
Includes: Supplemental data
Journal Articles

Modeling the Genotoxicity of Viral Vector Integration in a Tumor Prone Hematopoietic Stem Cell Transplantation Model.

Eugenio Montini, PhD, Daniela Cesana, Ms.Sci., Manfred Schmidt, Ph.D., Francesca Sanvito, M.D., Maurilio Ponzoni, M.D., Lucia Sergi Sergi, Ms.Sci., Fabrizio Benedicenti, Ms.Sci., Cynthia Bartholomae, Ms.Sci., Clelia Di Serio, Ph.D., Claudio Doglioni, M.D., Christof von Kalle, M.D., Luigi Naldini, M.D. Ph.D.
Journal: Blood
Blood (2006) 108 (11): 451.
https://doi.org/10.1182/blood.V108.11.451.451
Published: 2006
Journal Articles

Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells

Michele De Palma, Eugenio Montini, Francesca R. Santoni de Sio, Fabrizio Benedicenti, Alessandra Gentile, Enzo Medico, Luigi Naldini
Journal: Blood
Blood (2005) 105 (6): 2307–2315.
https://doi.org/10.1182/blood-2004-03-0798
Published: 2005