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Journal Articles

Anti-PF4 immunothrombosis without proximate heparin or adenovirus vector vaccine exposure

Blood (2023) 142 (26): 2305–2314.

https://doi.org/10.1182/blood.2023022136

Published: 2023

Includes: Supplemental data

Journal Articles

Immune thrombocytopenic purpura after vaccination with COVID-19 vaccine (ChAdOx1 nCov-19)

Finn-Ole Paulsen, Christoph Schaefers, Florian Langer, Christian Frenzel, Ulrich Wenzel, Felicitas E. Hengel, Carsten Bokemeyer, Christoph Seidel

Blood (2021) 138 (11): 996–999.

https://doi.org/10.1182/blood.2021012790

Published: 2021

Includes: Supplemental data

Journal Articles

Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development

Saravanan Subramaniam, Kerstin Jurk, Lukas Hobohm, Sven Jäckel, Mona Saffarzadeh, Kathrin Schwierczek, Philip Wenzel, Florian Langer, Christoph Reinhardt, Wolfram Ruf

Blood (2017) 129 (16): 2291–2302.

https://doi.org/10.1182/blood-2016-11-749879

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

Expression and Release of Platelet Protein Disulfide (PDI) Isomerase Is Increased in Patients with Hemophilia a

Florian Langer, Minna Voigtländer, Katharina Holstein, Brigitte Spath, Walter Fiedler, MD, Carsten Bokemeyer, MD

Blood (2015) 126 (23): 1085.

https://doi.org/10.1182/blood.V126.23.1085.1085

Published: 2015

Journal Articles

The polyphosphate–factor XII pathway drives coagulation in prostate cancer-associated thrombosis

Katrin F. Nickel, Göran Ronquist, Florian Langer, Linda Labberton, Tobias A. Fuchs, Carsten Bokemeyer, Guido Sauter, Markus Graefen, Nigel Mackman, Evi X. Stavrou, Gunnar Ronquist, Thomas Renné

Blood (2015) 126 (11): 1379–1389.

https://doi.org/10.1182/blood-2015-01-622811

Published: 2015

Includes: Supplemental data

Journal Articles

Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase

Florian Langer, Brigitte Spath, Cornelia Fischer, Moritz Stolz, Francis A. Ayuk, Nicolaus Kröger, Carsten Bokemeyer, Wolfram Ruf

Blood (2013) 121 (12): 2324–2335.

https://doi.org/10.1182/blood-2012-10-460493

Published: 2013

Includes: Supplemental data

Journal Articles

Characterization of the p.A1461D Mutation Causing Von Willebrand's Disease Type 2B with Severe Thrombocytopenia, Circulating Giant Platelets and Defective α -Granule Secretion

Florian Langer, MD, Tobias Obser, Florian Oyen, Katharina Holstein, MD, Brigitte Spath, Andreas Greinacher, MD, Ulrich Budde, MD, Carsten Bokemeyer, Reinhard Schneppenheim, MD, PhD

Blood (2012) 120 (21): 1074.

https://doi.org/10.1182/blood.V120.21.1074.1074

Published: 2012

Journal Articles

β 2 -Glycoprotein 1 Antibodies Directly Activate the Platelet IgG Receptor, FcγRIIa, and Cause Thrombosis in FCGR2A Transgenic but Not in Wild Type Mice

Ali Amirkhosravi, PhD, Todd V Meyer, PhD., Liza Robles-Carrillo, MS., Meghan Hatfield, M.S., Hina Desai, M.S., Mildred Amaya, M.S., Florian Langer, MD, Steven E. McKenzie, MD, PhD, John L Francis, PhD

Blood (2012) 120 (21): 106.

https://doi.org/10.1182/blood.V120.21.106.106

Published: 2012

Journal Articles

Differential Effects of Protein Disulfide Isomerase (PDI) Inhibitors On the Expression of Tissue Factor Procoagulant Activity (TF PCA) by AML Blasts

Cornelia Fischer, Brigitte Spath, Ali Amirkhosravi, PhD, Walter Fiedler, MD, Carsten Bokemeyer, Florian Langer, MD

Blood (2012) 120 (21): 1112.

https://doi.org/10.1182/blood.V120.21.1112.1112

Published: 2012

Journal Articles

Role of Protein Disulfide Isomerase (PDI) In the Expression of Tissue Factor (TF) Procoagulant Activity on Apoptotic Myeloblasts

Brigitte Spath, Ali Amirkhosravi, PhD, Monica Davila, PhD, John L. Francis, PhD, Barbara Eifrig, MD, Carsten Bokemeyer, MD, Florian Langer, MD

Blood (2010) 116 (21): 152.

https://doi.org/10.1182/blood.V116.21.152.152

Published: 2010

Journal Articles

Tissue Factor (TF) Activation by Antithymocyte Globulin Is Inhibited by a Novel Monoclonal Antibody Specific for Reduced TF Mutated at the Allosteric Cys186-Cys209 Disulfide.

Florian Langer, MD, Brigitte Spath, Francis Ayuketang Ayuk, MD, Nicolaus Kroeger, MD, Barbara Eifrig, MD, Carsten Bokemeyer, MD, Wolfram Ruf, MD

Blood (2010) 116 (21): 1132.

https://doi.org/10.1182/blood.V116.21.1132.1132

Published: 2010

Journal Articles

Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras

Arnab Ghosh, Wolfgang Koestner, Martin Hapke, Verena Schlaphoff, Florian Länger, Rolf Baumann, Christian Koenecke, Markus Cornberg, Karl Welte, Bruce R. Blazar, Martin G. Sauer

Blood (2009) 113 (18): 4440–4448.

https://doi.org/10.1182/blood-2008-09-181677

Published: 2009

Journal Articles

Mechanism of Thrombocytopenia Induced by Anti-CD40 Ligand Immune Complexes and the Prevalence of CD40 Ligand Autoantibodies in Patients with Thrombotic Autoimmune Disorders

Ali Amirkhosravi, Ph.D., Todd V Meyer, Ph.D., Liza Robles-Carillo, MS, Monica Davila, Ph.D., Florian Langer, MD, Hina Desai, MS, Patricia Weinstein, RN, Mildred Amaya, MS, Eduardo Reyes, MS, John L Francis, Ph.D.

Blood (2008) 112 (11): 2857.

https://doi.org/10.1182/blood.V112.11.2857.2857

Published: 2008

Journal Articles

Bevacizumab Immune Complexes Induce Thrombocytopenia and Thrombosis in Mice Transgenic for Human IgG Receptor FcYIIa

Ali Amirkhosravi, Ph.D., Todd V Meyer, Ph.D., Liza Robles-Carillo, MS, Florian Langer, MD, Theresa Robson, BS, Hina Desai, MS, Monica Davila, Ph.D., Mildred Amaya, MS, John L. Francis, Ph.D.

Blood (2008) 112 (11): 114.

https://doi.org/10.1182/blood.V112.11.114.114

Published: 2008

Journal Articles

Microparticle-Associated Tissue Factor: A Molecular Link Between Coagulation Activation, Inflammation and Disease Progression in Early-Stage Prostate Cancer?

Katja Haubold, Michael Rink, Brigitte Spath, Ali Amirkhosravi, John L. Francis, Barbara Eifrig, Carsten Bokemeyer, MD, Florian Langer

Blood (2008) 112 (11): 3813.

https://doi.org/10.1182/blood.V112.11.3813.3813

Published: 2008

Journal Articles

Hypercoagulability in Ovarian Cancer Revisited: A Prospective Analysis of Coagulation and Platelet Activation Markers.

Ali Amirkhosravi, PhD, Glenn Bigsby, IV, D.O., Hina Desai, M.S., Mildred Amaya, M.S., Enriqueta Coll, Ph.D., Liza Robles, M.S., Patricia Faust, R.N., Florian Langer, M.D., Alane Drexler, R.N., Edward Reyes, M.S., John L. Francis, Ph.D.

Blood (2006) 108 (11): 1762.

https://doi.org/10.1182/blood.V108.11.1762.1762

Published: 2006

Journal Articles

Platelet Activation by a Humanized Monoclonal CD40 Ligand (CD40L) Antibody.

Todd Meyer, PhD, Ali Amirkhosravi, Ph.D., Theresa Robson, B.A., Mildred Amaya, M.S., Desai Hina, M.S., Lihe Su, Ph.D., Yen-Ming Hsu, Ph.D., Florian Langer, M.D., John L. Francis, Ph.D.

Blood (2006) 108 (11): 1516.

https://doi.org/10.1182/blood.V108.11.1516.1516

Published: 2006

Journal Articles

Targeting Angiogenesis in Cancer: Bevacizumab-Induced Platelet Activation as a Possible Cause for Unexpected Arterial Thromboembolic Events in Clinical Trials.

Todd Meyer, PhD, Theresa Robson, B.S., Ali Amirkhosravi, Ph.D., Florian Langer, M.D., Hina Desai, M.S., Mildred Amaya, M.S., Pierre Elias, John L. Francis, Ph.D.

Blood (2006) 108 (11): 1091.

https://doi.org/10.1182/blood.V108.11.1091.1091

Published: 2006

Journal Articles

Blood-Borne, but Not Endothelial CD40 Promotes Experimental Lung Metastasis.

Ali Amirkhosravi, PhD, Susan B. Ingersoll, Ph.D., Theresa Robson, BS, Florian Langer, M.D., Jamie Walker, BS, John L. Francis, Ph.D.

Blood (2006) 108 (11): 1092.

https://doi.org/10.1182/blood.V108.11.1092.1092

Published: 2006

Journal Articles

Mechanisms of Platelet Activation by Antithymocyte Globulin (ATG).

Florian Langer, Francis A. Ayuk, Ali Amirkhosravi, Brigitte Spath, Todd Meyer, Theresa Robson, Liza Robles, Guy Marx, Simon D. Lytton, Katharina Holstein, Barbara Eifrig, Carsten Bokemeyer, Axel R. Zander, Nicolaus Kroeger

Blood (2006) 108 (11): 3905.

https://doi.org/10.1182/blood.V108.11.3905.3905

Published: 2006

NARROW

Anti-PF4 immunothrombosis without proximate heparin or adenovirus vector vaccine exposure

Immune thrombocytopenic purpura after vaccination with COVID-19 vaccine (ChAdOx1 nCov-19)

Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development

Expression and Release of Platelet Protein Disulfide (PDI) Isomerase Is Increased in Patients with Hemophilia a

The polyphosphate–factor XII pathway drives coagulation in prostate cancer-associated thrombosis

Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase

Characterization of the p.A1461D Mutation Causing Von Willebrand's Disease Type 2B with Severe Thrombocytopenia, Circulating Giant Platelets and Defective α -Granule Secretion

β 2 -Glycoprotein 1 Antibodies Directly Activate the Platelet IgG Receptor, FcγRIIa, and Cause Thrombosis in FCGR2A Transgenic but Not in Wild Type Mice

Differential Effects of Protein Disulfide Isomerase (PDI) Inhibitors On the Expression of Tissue Factor Procoagulant Activity (TF PCA) by AML Blasts

Role of Protein Disulfide Isomerase (PDI) In the Expression of Tissue Factor (TF) Procoagulant Activity on Apoptotic Myeloblasts

Tissue Factor (TF) Activation by Antithymocyte Globulin Is Inhibited by a Novel Monoclonal Antibody Specific for Reduced TF Mutated at the Allosteric Cys186-Cys209 Disulfide.

Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras

Mechanism of Thrombocytopenia Induced by Anti-CD40 Ligand Immune Complexes and the Prevalence of CD40 Ligand Autoantibodies in Patients with Thrombotic Autoimmune Disorders

Bevacizumab Immune Complexes Induce Thrombocytopenia and Thrombosis in Mice Transgenic for Human IgG Receptor FcYIIa

Microparticle-Associated Tissue Factor: A Molecular Link Between Coagulation Activation, Inflammation and Disease Progression in Early-Stage Prostate Cancer?

Hypercoagulability in Ovarian Cancer Revisited: A Prospective Analysis of Coagulation and Platelet Activation Markers.

Platelet Activation by a Humanized Monoclonal CD40 Ligand (CD40L) Antibody.

Targeting Angiogenesis in Cancer: Bevacizumab-Induced Platelet Activation as a Possible Cause for Unexpected Arterial Thromboembolic Events in Clinical Trials.

Blood-Borne, but Not Endothelial CD40 Promotes Experimental Lung Metastasis.

Mechanisms of Platelet Activation by Antithymocyte Globulin (ATG).

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American Society of Hematology

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American Society of Hematology

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