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Francesca Pellicano
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Journal Articles

hsa-mir183/EGR1 –mediated regulation of E2F1 is required for CML stem/progenitor cell survival

Francesca Pellicano, Laura Park, Lisa E. M. Hopcroft, Mansi M. Shah, Lorna Jackson, Mary T. Scott, Cassie J. Clarke, Amy Sinclair, Sheela A. Abraham, Alan Hair, G. Vignir Helgason, Mark Aspinall-O’Dea, Ravi Bhatia, Gustavo Leone, Kamil R. Kranc, Anthony D. Whetton, Tessa L. Holyoake
Journal: Blood
Blood (2018) 131 (14): 1532–1544.
https://doi.org/10.1182/blood-2017-05-783845
Published: 2018
Includes: Supplemental data
Journal Articles

CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression

Anuradha Tarafdar, Lisa E. M. Hopcroft, Paolo Gallipoli, Francesca Pellicano, Jennifer Cassels, Alan Hair, Koorosh Korfi, Heather G. Jørgensen, David Vetrie, Tessa L. Holyoake, Alison M. Michie
Journal: Blood
Blood (2017) 129 (2): 199–208.
https://doi.org/10.1182/blood-2016-09-742049
Published: 2017
Includes: Supplemental data
Journal Articles

CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells

Amy Sinclair, Laura Park, Mansi Shah, Mark Drotar, Simon Calaminus, Lisa E. M. Hopcroft, Ross Kinstrie, Amelie V. Guitart, Karen Dunn, Sheela A. Abraham, Owen Sansom, Alison M. Michie, Laura Machesky, Kamil R. Kranc, Gerard J. Graham, Francesca Pellicano, Tessa L. Holyoake
Journal: Blood
Blood (2016) 128 (3): 371–383.
https://doi.org/10.1182/blood-2015-08-661785
Published: 2016
Includes: Supplemental data
Journal Articles

p53 and c-Myc Are Critical Signaling Hubs That Maintain Chronic Myeloid Leukemia

Sheela A Abraham, PhD, Lisa Hopcroft, PhD, Emma Carrick, PhD, Andrew Williamson, PhD, Andrew Pierce, PhD, Jennifer Cassels, Francesca Pellicano, PhD, Anthony Whetton, Tessa L Holyoake, PhD, MB, ChB, FRCP, FRCPath, FRSE
Journal: Blood
Blood (2013) 122 (21): 1465.
https://doi.org/10.1182/blood.V122.21.1465.1465
Published: 2013
Journal Articles

Autocrine TNF-α production supports CML stem and progenitor cell survival and enhances their proliferation

Brief Report
Paolo Gallipoli, Francesca Pellicano, Heather Morrison, Kamilla Laidlaw, Elaine K. Allan, Ravi Bhatia, Mhairi Copland, Heather G. Jørgensen, Tessa L. Holyoake
Journal: Blood
Blood (2013) 122 (19): 3335–3339.
https://doi.org/10.1182/blood-2013-02-485607
Published: 2013
Includes: Supplemental data
Journal Articles

BMS-214662 Eliminates Quiescent and Proliferating Acute Myeloid Leukemia Cells through Activation of Protein Kinase Cβ and Enhances the Efficacy of Cytosine Arabinoside

Francesca Pellicano, PhD, Amy Sinclair, BSc, MSc, Alan Hair, BSc, PhD, Tessa L. Holyoake, PhD, FRCP, FRCPath, Mhairi Copland, PhD, BSc, MRCP, FRCPath
Journal: Blood
Blood (2010) 116 (21): 2167.
https://doi.org/10.1182/blood.V116.21.2167.2167
Published: 2010
Journal Articles

Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells

Nicholas B. Heaney, Francesca Pellicano, Bin Zhang, Lisa Crawford, Su Chu, Syed M. A. Kazmi, Elaine K. Allan, Heather G. Jorgensen, Alexandra E. Irvine, Ravi Bhatia, Tessa L. Holyoake
Journal: Blood
Blood (2010) 115 (11): 2241–2250.
https://doi.org/10.1182/blood-2008-06-164582
Published: 2010
Includes: Supplemental data
Journal Articles

Foxo Transcription Factor Activity Is Retained in Quiescent Chronic Myeloid Leukaemia Stem Cells and Activated by Tyrosine Kinase Inhibitors to Mediate “induced-quiescence” in More Mature progenitors.

Daniela Cilloni, MD, PhD, Francesca Pellicano, PhD, Vignir G Helgason, PhD, Cristina Panuzzo, PhD, Francesca Messa, PhD, Brian J Huntly, MD, Elaine Allan, PhD, Francesca Arruga, PhD, Enrico Bracco, PhD, Giuseppe Saglio, MD, Tessa L Holyoake, MD
Journal: Blood
Blood (2009) 114 (22): 187.
https://doi.org/10.1182/blood.V114.22.187.187
Published: 2009
Journal Articles

BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34 + 38 − cells, through activation of protein kinase Cβ

Francesca Pellicano, Mhairi Copland, Heather G. Jorgensen, Joanne Mountford, Brian Leber, Tessa L. Holyoake
Journal: Blood
Blood (2009) 114 (19): 4186–4196.
https://doi.org/10.1182/blood-2009-05-219550
Published: 2009
Includes: Supplemental data
Journal Articles

BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors

Mhairi Copland, Francesca Pellicano, Linda Richmond, Elaine K. Allan, Ashley Hamilton, Francis Y. Lee, Roberto Weinmann, Tessa L. Holyoake
Journal: Blood
Blood (2008) 111 (5): 2843–2853.
https://doi.org/10.1182/blood-2007-09-112573
Published: 2008
Includes: Supplemental data
Journal Articles

Bortezomib Has Anti-Proliferative and Apoptotic Effects Against CML Stem Cells, Including the Quiescent Population.

Nicholas Heaney, Francesca Pellicano, Lisa Crawford, Sandra Irvine, Tessa L. Holyoake
Journal: Blood
Blood (2007) 110 (11): 2943.
https://doi.org/10.1182/blood.V110.11.2943.2943
Published: 2007