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Friederike Pastore
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Journal Articles

Phase 1 Study of JNJ-64619178, a Protein Arginine Methyltransferase 5 Inhibitor, in Patients with Lower-Risk Myelodysplastic Syndromes

Tamanna Haque, Felix López Cadenas, Blanca Xicoy, Ana Alfonso, Uwe Platzbecker, Irit Avivi, Andrew M. Brunner, Jörg Chromik, Daniel Morillo, Manish R. Patel, José F. Falantes, Heather A. Leitch, Ulrich Germing, Meir Preis, David Lavie, Laurie Lenox, Josh Lauring, Anna Kalota, Regina Brown, Jaydeep Mehta, Friederike Pastore, Pankaj Mistry, David Valcarcel
Journal: Blood
Blood (2021) 138 (Supplement 1): 2606.
https://doi.org/10.1182/blood-2021-146987
Published: 2021
Journal Articles

PRMT5 Inhibition Modulates E2F1 Methylation and Gene Regulatory Networks Leading to Therapeutic Efficacy in JAK2VF Mutant MPN

Friederike Pastore, MD, Neha Bhagwat, PhDBS, Aishwarya Krishnan, Alessandro Pastore, Bing Li, MD, Robert L Bowman, PhD, Wenbin Xiao, MD PhD, Aaron D Viny, MDMS, Abdul Karzai, Anouar Zouak, Young C Park, Keith Cordner, Stephanie Braunstein, Alexander Grego, Jaanvi Mehta, Benjamin H Durham, MD, Richard P. Koche, PhD, Jesper Maag, Peggy Scherle, PhD, Kris Vaddi, PhD, Ross L. Levine, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 473.
https://doi.org/10.1182/blood-2019-127122
Published: 2019
Journal Articles

PHF6 Mutations Are Mutually Exclusive to TP53 Mutations, and Define a Distinct Subgroup of Secondary Acute Myeloid Leukemia Associated with a Primitive Stem/Progenitor Immunophenotype, Absent Complex Karyotype and Relatively Better Outcomes

Wenbin Xiao, MD, Aaron D Goldberg, MD PhD, Brian Ball, Christopher Famulare, MS, Friederike Pastore, MD, Martin S. Tallman, MD, Yanming Zhang, MD, Maria E Arcila, MD, Elli Papaemmanuil, PhD, Ross L. Levine, MD, Mikhail Roshal, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2788.
https://doi.org/10.1182/blood-2018-99-118985
Published: 2018
Journal Articles

PHF6 Mutations Defines a Subgroup of Mixed Phenotype of Acute Leukemia with Aberrant T-Cell Differentiation

Wenbin Xiao, MD, Friederike Pastore, MD, Bartlomiej Getta, MD, Anne Hultquist, MD, Brian C. Shaffer, MD, Sergio A. Giralt, MD, Raajit K. Rampal, MD PhD, Maria E. Arcila, Ross L. Levine, MD, Mikhail Roshal, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1384.
https://doi.org/10.1182/blood.V130.Suppl_1.1384.1384
Published: 2017
Journal Articles

Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse

Sebastian Vosberg, Luise Hartmann, MSc, Klaus H Metzeler, MD, Daniela Schumacher, Friederike Pastore, MD, Kathrin Bräundl, Evelyn Zellmeier, Bianka Ksienzyk, Nikola P Konstandin, PhD, Stephanie Schneider, PhD, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Martin Neumann, MD, Claudia D. Baldus, MD, Stefan K. Bohlander, MD, Stephan Wolf, PhD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Philipp A. Greif, MD
Journal: Blood
Blood (2016) 128 (22): 288.
https://doi.org/10.1182/blood.V128.22.288.288
Published: 2016
Journal Articles

Mutations of Genes Linked to Epigenetic Regulation Are Frequently Gained in Relapsed Cytogenetically Normal Acute Myeloid Leukemia

Luise Hartmann, MSc, Sebastian Vosberg, Klaus H. Metzeler, MD, Daniela Schumacher, Friederike Pastore, MD, Kathrin Bräundl, Evelyn Zellmeier, Bianka Ksienzyk, Nikola P Konstandin, PhD, Stephanie Schneider, PhD, Stefan Krebs, PhD, Alexander Graf, PhD, Helmut Blum, PhD, Martin Neumann, MD, Claudia D Baldus, MD, Stefan K. Bohlander, MD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Philipp A. Greif, MD
Journal: Blood
Blood (2015) 126 (23): 690.
https://doi.org/10.1182/blood.V126.23.690.690
Published: 2015
Journal Articles

Genetic Evolution of Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) during Therapy and Relapse: An Exome Sequencing Study of 47 Cases

Luise Hartmann, Sebastian Vosberg, Klaus H. Metzeler, MD, Daniela Schumacher, Friederike Pastore, MD, Kathrin Bräundl, Evelyn Zellmeier, Bianka Ksienzyk, Nikola P Konstandin, Stephanie Schneider, PhD, Alexander Graf, Helmut Blum, PhD, Martin Neumann, MD, Claudia D Baldus, MD, Stefan K Bohlander, MD, Stephan Wolf, PhD, Stefan Wiemann, PhD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Philipp A Greif, MD
Journal: Blood
Blood (2014) 124 (21): 17.
https://doi.org/10.1182/blood.V124.21.17.17
Published: 2014
Journal Articles

A Combined Molecular and Clinical Prognostic Index For Relapse and Survival In Cytogenetically Normal AML (PINA)

Friederike Pastore, MD, Annika Dufour, PhD, Tobias Benthaus, MD, Klaus H. Metzeler, MD, Kati Maharry, MAS, Stephanie Schneider, PhD, Bianka Ksienzyk, Gudrun Mellert, Evelyn Zellmeier, Purvi M. Kakadia, PhD, Michael Unterhalt, M.D. Ph.D., Michaela Feuring-Buske, MD, Christian Buske, MD, Jan Braess, MD, Cristina Sauerland, MSc, Achim Heinecke, PhD, Utz Krug, MD, Wolfgang E. Berdel, MD, Thomas Büchner, MD, Bernhard J. Woermann, MD, Wolfgang Hiddemann, MD, Stefan K. Bohlander, MD, Guido Marcucci, MD, Karsten Spiekermann, MD, Clara D. Bloomfield, MD, Eva Hoster, PhD
Journal: Blood
Blood (2013) 122 (21): 1303.
https://doi.org/10.1182/blood.V122.21.1303.1303
Published: 2013