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Journal Articles

Safety and Preliminary Efficacy of Sabestomig (AZD7789), an Anti-PD-1 and Anti-TIM-3 Bispecific Antibody, in Patients with Relapsed or Refractory Classical Hodgkin Lymphoma Previously Treated with Anti-PD-(L)1 Therapy

Blood (2023) 142 (Supplement 1): 4433.

https://doi.org/10.1182/blood-2023-180926

Published: 2023

Journal Articles

Edo-S101, a Bendamustine (BDM)/ Histone-Deacetylase Inhibitor (HDACi) Fusion Molecule, Demonstrates Potent Preclinical Activity Against T-Cell Malignancies and Overcomes BDM-Resistance

Rosaria De Filippi, MD PhD, Stefania Crisci, ScD, Sara Mele, BS, Serena Zanotta, ScD, Gaetano Corazzelli, MD, Domenico Galati, MD PhD, Davide Coppola, RN, Piera Maiolino, PharmD, Mariangela Saggese, PharmD, Francesco Volzone, MD, Emanuela Morelli, MD, Daniela Donnarumma, MD, Gianpaolo Marcacci, MD, Ferdinando Frigeri, MD, Niels Odum, MD, Thomas Mehrling, MD PhD, Antonio Pinto, MD

Blood (2017) 130 (Supplement 1): 2547.

https://doi.org/10.1182/blood.V130.Suppl_1.2547.2547

Published: 2017

Journal Articles

Dendritic Cells Subsets Profiles in Classical Hodgkin Lymphoma at Diagnosis and upon Treatment Completion: Analysis on 54 Patients

Domenico Galati, MD PhD, Serena Zanotta, ScD, Gaetano Corazzelli, MD, Bruzzese Dario, PhD, Gaetana Capobianco, MD, Emanuela Morelli, MD, Manuela Arcamone, MD, Ferdinando Frigeri, MD, Rosaria De Filippi, MD PhD, Antonio Pinto, MD

Blood (2017) 130 (Supplement 1): 4095.

https://doi.org/10.1182/blood.V130.Suppl_1.4095.4095

Published: 2017

Journal Articles

Continuous Exposure to Bendamustine (BDM) Results in Stable Upregulation of CD30 and Increased Sensitivity to Brentuximab Vedotin (BV) in Tumor Cells of Hodgkin Lymphoma (HL)

Rosaria De Filippi, MD PhD, Michele Cillo, ScD, Stefania Crisci, ScD, Sara Mele, BS, Serena Zanotta, ScD, Angela De Monaco, ScD, Domenico Galati, MD, Giancarla Iaccarino, ScD, Raffaele Di Francia, ScD, Emanuela Morelli, MD, Gianpaolo Marcacci, MD, Cristina Becchimanzi, MD, Attilio Guarini, MD, Ferdinando Frigeri, MD PhD, Gaetano Corazzelli, MD, Antonello Pinto, MD

Blood (2015) 126 (23): 2479.

https://doi.org/10.1182/blood.V126.23.2479.2479

Published: 2015

Journal Articles

The First-in-Class Alkylating Histone-Deacetylase Inhibitor (HDACi) Fusion Molecule Edo-S101 Exerts Potent Preclinical Activity Against Tumor Cells of Hodgkin Lymphoma (HL) Including Bendamustine-Resistant Clones

Rosaria De Filippi, MD PhD, Stefania Crisci, ScD, Michele Cillo, ScD, Sara Mele, BS, Angela De Monaco, ScD, Domenico Galati, MD, Serena Zanotta, ScD, Gaetana Capobianco, MD, Francesco Volzone, MD, Manuela Arcamone, MD, Piera Maiolino, PharmD, Mariangela Saggese, PharmD, Gaetano Corazzelli, MD, Ferdinando Frigeri, MD PhD, Thomas Mehrling, MD PhD, Antonello Pinto, MD

Blood (2015) 126 (23): 2481.

https://doi.org/10.1182/blood.V126.23.2481.2481

Published: 2015

Journal Articles

Lenalidomide in Combination with Bendamustine for Patients with Chemorefractory Hodgkin Lymphoma: Final Results of the Leben Multicenter Phase 1/2 Study

Antonello Pinto, MD, Vincenzo Pavone, MD, Francesco Angrilli, MD, Mariangela Saggese, PharmD, Stefania Crisci, ScD, Caterina Patti, MD, Pier Luigi Zinzani, MD PhD, Alfonso Maria D'Arco, MD, Elena Cavalieri, MD, Attilio Guarini, MD, Michele Spina, MD, Daniela Carlino, MD, Simona Falorio, MD, Emanuela Morelli, MD, Manuela Arcamone, MD, Ferdinando Frigeri, MD PhD, Annarosaria De Chiara, MD, Rosaria De Filippi, MD PhD, Gaetano Corazzelli, MD

Blood (2015) 126 (23): 1541.

https://doi.org/10.1182/blood.V126.23.1541.1541

Published: 2015

Journal Articles

Molecular Determinants of Bendamustine (BDM) Toxicity towards Hodgkin (H) and Reed-Sternberg (RS) Cell Lines From Hodgkin Lymphoma (HL).

Rosaria De Filippi, MD, PhD, Stefania Crisci, PhD, Ferdinando Frigeri, MD, PhD, Donatella Aldinucci, PhD, Domenico Galati, MD, Rosa Calemma, PhD, Giulio Abagnale, PhD, Gaetana Capobianco, MD, Manuela Arcamone, MD, Raffaele Di Francia, DPharm, Laura Mettivier, MD, Mariangela Saggese, PhD, Gaetano Corazzelli, MD, Antonio Pinto, MD

Blood (2012) 120 (21): 2763.

https://doi.org/10.1182/blood.V120.21.2763.2763

Published: 2012

Journal Articles

Gemcitabine, Ifosfamide, Oxaliplatin (GIFOX) as First-Line Treatment In High-Risk Peripheral T-Cell/NK Lymphomas: A Phase II Trial.

Gaetano Corazzelli, MD, Ferdinando Frigeri, MD, Gianpaolo Marcacci, MD, Cristina Becchimanzi, MD, Gaetana Capobianco, MD, Manuela Arcamone, MD, Emanuela Morelli, MD, Francesco Volzone, MD, Filippo Russo, MD, Antonio Pinto, MD

Blood (2010) 116 (21): 2829.

https://doi.org/10.1182/blood.V116.21.2829.2829

Published: 2010

Journal Articles

Clinical Relevance of the Dose of Cytarabine In the Treatment of Primary CNS Lymphomas with Methotrexate-Cytarabine Chemotherapy Combination

Andrés JM Ferreri, MD, Giada Licata, Marco Foppoli, Gaetano Corazzelli, Emanuele Zucca, Caterina Stelitano, Francesco Zaja, Sergio Fava, Rossella Paolini, Alberto Franzin, Letterio Politi, Maurilio Ponzoni, MD, Michele Reni

Blood (2010) 116 (21): 1780.

https://doi.org/10.1182/blood.V116.21.1780.1780

Published: 2010

Journal Articles

Biweekly Rituximab, Cyclophosphamide, Vincristine, Non-Pegylated Liposome-Encapsulated Doxorubicin (Myocet®) and Prednisone (R-COMP-14) as Induction Treatment in Poor R-IPI Risk Elderly Patients with Diffuse Large B-Cell Lymphoma (DLBCL) and Pre-Existing Heart Disease.

Ferdinando Frigeri, MD, Gaetano Corazzelli, MD, Manuela Arcamone, MD, Gaetana Capobianco, MD, Anna Lucania, MD, Cristina Becchimanzi, MD, Gianpaolo Marcacci, MD, Filippo Russo, MD, Maria Rosaria Villa, MD, Lucia Mastrullo, MD, Antonio Pinto, MD

Blood (2009) 114 (22): 1664.

https://doi.org/10.1182/blood.V114.22.1664.1664

Published: 2009

Journal Articles

Dose-Dense(dd) ABVD and Dose-Dense/Dose-Intense(dd-di) ABVD in Newly Diagnosed Patients (pts), Intermediate- and Advanced-Stage with Classical Hodgkin's Lymphoma (cHL): Final Results.

Filippo Russo, MD, Gaetano Corazzelli, MD, Secondo Lastoria, MD, Gianpaolo Marcacci, MD, Ferdinando Frigeri, MD, Gaetana Capobianco, Cristina Becchimanzi, MD, Manuela Arcamone, MD, Antonio Pinto, MD

Blood (2009) 114 (22): 715.

https://doi.org/10.1182/blood.V114.22.715.715

Published: 2009

Journal Articles

Safety and Efficacy of Intrathecal Liposome-Encapsulated Cytarabine for Central Nervous System (CNS) Prophylaxis in Adult Patients with Burkitt and Atypical Burkitt Lymphoma Treated with the R-CODOX-M/R-IVAC (Magrath) Regimen: Results of a Phase II Study.

Ferdinando Frigeri, MD, Filippo Russo, MD, Manuela Arcamone, MD, Chiara Fraira, MD, Gennaro Russo, MD, Gaetana Capobianco, MD, Cristina Becchimanzi, MD, Arturo Cuomo, MD, Gianpaolo Marcacci, MD, Gennaro Esposito, MD, Rosaria De Filippi, MD, PhD, Gaetano Corazzelli, MD, Umberto Vitolo, MD, Antonio Pinto, MD

Blood (2009) 114 (22): 3716.

https://doi.org/10.1182/blood.V114.22.3716.3716

Published: 2009

Journal Articles

Abnormally Elevated Levels of Serum Free-Immunoglobulin Light Chains Are Frequently Found in Classic Hodgkin Lymphoma (cHL) and Predict Outcome of Patients with Early Stage Disease.

Rosaria De Filippi, MD, PhD, Filippo Russo, MD, Giancarla Iaccarino, D.Sci, Stefania Crisci, D.Sci, Ferdinando Frigeri, Costantino Riemma, Alessandro Marchei, D.Sci, Rosa Calemma, D.Sci, Raffaele Di Francia, D.Pharm, Gianpaolo Marcacci, MD, Gaetano Corazzelli, MD, Gaetana Capobianco, MD, Cristina Becchimanzi, MD, Manuela Arcamone, MD, Barbara Amoroso, MD, Giuseppe Castello, MD, Antonio Pinto, MD

Blood (2009) 114 (22): 267.

https://doi.org/10.1182/blood.V114.22.267.267

Published: 2009

Journal Articles

Rituximab Plus Gemcitabine, Ifosfamide, Oxaliplatin (R-GIFOX), a New Effective Cytoreductive/Mobilizing Salvage Regimen for Relapsed and Refractory Hodgkin Lymphoma

Gaetano Corazzelli, Gaetana Capobianco, Manuela Arcamone, Cristina Becchimanzi, Giampaolo Marcacci, Ferdinando Frigeri, Filippo Russo, Antonio Pinto

Blood (2008) 112 (11): 2601.

https://doi.org/10.1182/blood.V112.11.2601.2601

Published: 2008

Journal Articles

Randomized Phase II Trial on Primary Chemotherapy with High-Dose Methotrexate Alone or Associated with High-Dose Cytarabine for Patients with Primary CNS Lymphoma (IELSG #20 Trial): Tolerability, Activity and Event-Free Survival Analysis

Blood (2008) 112 (11): 580.

https://doi.org/10.1182/blood.V112.11.580.580

Published: 2008

Journal Articles

Dose Dense and Dose Intense ABVD (dd-di ABVD) in Advanced and Intermediate-Stage Hodgkin’s Lymphoma (HL).

Filippo Russo, MD, Gaetano Corazzelli, MD, Ferdinando Frigeri, MD, Gianpaolo Marcacci, MD, Antonio Pinto

Blood (2007) 110 (11): 2324.

https://doi.org/10.1182/blood.V110.11.2324.2324

Published: 2007

Journal Articles

Cladribine (2-CDA) Plus Sequential Rituximab in Newly Diagnosed Disseminated Extranodal Marginal Zone B-Cell Lymphomas. A Phase II Study.

Gaetano Corazzelli, MD, Gaetana Capobianco, MD, Filippo Russo, MD, Oreste Villani, MD, Patrizia Vassallo, MD, Antonio Pinto, MD

Blood (2006) 108 (11): 2761.

https://doi.org/10.1182/blood.V108.11.2761.2761

Published: 2006

Journal Articles

100% of Complete Response (CR) and Survival (FFP, OS) in Newly Diagnosed Patients with Advanced- and Intermediate-Stage Hodgkin’s Lymphoma (HL) Treated with Six Cycles of Dose-Dense, Dose-Intense (DD-DI) ABVD without Radiotherapy (RT).

Filippo Russo, MD, Gaetano Corazzelli, MD, Ferdinando Frigeri, MD, Secondo LaStoria, Antonio Pinto

Blood (2006) 108 (11): 2476.

https://doi.org/10.1182/blood.V108.11.2476.2476

Published: 2006

Journal Articles

The Impact of Relative Dose Intensity on Response and Survival in a Series of 180 Newly Diagnosed Patients with Hodgkin’s Lymphoma.

Filippo Russo, MD, Gino Svanera, MD, Paola Della Cioppa, MD, Gaetano Corazzelli, MD, Ferdinando Frigeri, MD, Gaetana Capobianco, MD, Secondo LaStoria, MD, Antonio Pinto, MD

Blood (2005) 106 (11): 2671.

https://doi.org/10.1182/blood.V106.11.2671.2671

Published: 2005

Journal Articles

Gemcitabine, Ifosfamide, Oxaliplatin and Rituximab (R-GIFOX), a New Effective Cytoreductive/Mobilizing Salvage Regimen for Relapsed and Refractory Aggressive Non-Hodgkin’s Lymphoma: Results of a Pilot Study.

Gaetano Corazzelli, MD, Filippo Russo, MD, Gaetana Capobianco, MD, Gianpaolo Marcacci, MD, Paola Della Cioppa, MD, Antonio Pinto, MD

Blood (2005) 106 (11): 940.

https://doi.org/10.1182/blood.V106.11.940.940

Published: 2005

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Safety and Preliminary Efficacy of Sabestomig (AZD7789), an Anti-PD-1 and Anti-TIM-3 Bispecific Antibody, in Patients with Relapsed or Refractory Classical Hodgkin Lymphoma Previously Treated with Anti-PD-(L)1 Therapy

Edo-S101, a Bendamustine (BDM)/ Histone-Deacetylase Inhibitor (HDACi) Fusion Molecule, Demonstrates Potent Preclinical Activity Against T-Cell Malignancies and Overcomes BDM-Resistance

Dendritic Cells Subsets Profiles in Classical Hodgkin Lymphoma at Diagnosis and upon Treatment Completion: Analysis on 54 Patients

Continuous Exposure to Bendamustine (BDM) Results in Stable Upregulation of CD30 and Increased Sensitivity to Brentuximab Vedotin (BV) in Tumor Cells of Hodgkin Lymphoma (HL)

The First-in-Class Alkylating Histone-Deacetylase Inhibitor (HDACi) Fusion Molecule Edo-S101 Exerts Potent Preclinical Activity Against Tumor Cells of Hodgkin Lymphoma (HL) Including Bendamustine-Resistant Clones

Lenalidomide in Combination with Bendamustine for Patients with Chemorefractory Hodgkin Lymphoma: Final Results of the Leben Multicenter Phase 1/2 Study

Molecular Determinants of Bendamustine (BDM) Toxicity towards Hodgkin (H) and Reed-Sternberg (RS) Cell Lines From Hodgkin Lymphoma (HL).

Gemcitabine, Ifosfamide, Oxaliplatin (GIFOX) as First-Line Treatment In High-Risk Peripheral T-Cell/NK Lymphomas: A Phase II Trial.

Clinical Relevance of the Dose of Cytarabine In the Treatment of Primary CNS Lymphomas with Methotrexate-Cytarabine Chemotherapy Combination

Biweekly Rituximab, Cyclophosphamide, Vincristine, Non-Pegylated Liposome-Encapsulated Doxorubicin (Myocet®) and Prednisone (R-COMP-14) as Induction Treatment in Poor R-IPI Risk Elderly Patients with Diffuse Large B-Cell Lymphoma (DLBCL) and Pre-Existing Heart Disease.

Dose-Dense(dd) ABVD and Dose-Dense/Dose-Intense(dd-di) ABVD in Newly Diagnosed Patients (pts), Intermediate- and Advanced-Stage with Classical Hodgkin's Lymphoma (cHL): Final Results.

Safety and Efficacy of Intrathecal Liposome-Encapsulated Cytarabine for Central Nervous System (CNS) Prophylaxis in Adult Patients with Burkitt and Atypical Burkitt Lymphoma Treated with the R-CODOX-M/R-IVAC (Magrath) Regimen: Results of a Phase II Study.

Abnormally Elevated Levels of Serum Free-Immunoglobulin Light Chains Are Frequently Found in Classic Hodgkin Lymphoma (cHL) and Predict Outcome of Patients with Early Stage Disease.

Rituximab Plus Gemcitabine, Ifosfamide, Oxaliplatin (R-GIFOX), a New Effective Cytoreductive/Mobilizing Salvage Regimen for Relapsed and Refractory Hodgkin Lymphoma

Randomized Phase II Trial on Primary Chemotherapy with High-Dose Methotrexate Alone or Associated with High-Dose Cytarabine for Patients with Primary CNS Lymphoma (IELSG #20 Trial): Tolerability, Activity and Event-Free Survival Analysis

Dose Dense and Dose Intense ABVD (dd-di ABVD) in Advanced and Intermediate-Stage Hodgkin’s Lymphoma (HL).

Cladribine (2-CDA) Plus Sequential Rituximab in Newly Diagnosed Disseminated Extranodal Marginal Zone B-Cell Lymphomas. A Phase II Study.

100% of Complete Response (CR) and Survival (FFP, OS) in Newly Diagnosed Patients with Advanced- and Intermediate-Stage Hodgkin’s Lymphoma (HL) Treated with Six Cycles of Dose-Dense, Dose-Intense (DD-DI) ABVD without Radiotherapy (RT).

The Impact of Relative Dose Intensity on Response and Survival in a Series of 180 Newly Diagnosed Patients with Hodgkin’s Lymphoma.

Gemcitabine, Ifosfamide, Oxaliplatin and Rituximab (R-GIFOX), a New Effective Cytoreductive/Mobilizing Salvage Regimen for Relapsed and Refractory Aggressive Non-Hodgkin’s Lymphoma: Results of a Pilot Study.

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