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Journal Articles

Donor natural killer cells trigger production of β-2-microglobulin to enhance post–bone marrow transplant immunity

Blood (2022) 140 (22): 2323–2334.

https://doi.org/10.1182/blood.2021015297

Published: 2022

Includes: Supplemental data

Journal Articles

Engineering Regenerative Thymic Tissues to Restore Long-Term T Cell Lymphopoiesis

Hui Gai, MD, Rafa Gras~Pena, PhD, Yogendra Verma, MS, Vincent Fateh, BS, Kazuya Ikeda, MD, Beruh Dejene, MS, Dullei Min, Jing Wang, MD, Tomek Swigut, PhD, Ken I. Weinberg, MD, Georg A. Hollander, MD, Sarah Heilshorn, PhD, Maria-Grazia Roncarolo, MD, Vittorio Sebastiano, PhD, Katja G. Weinacht, MD PhD

Blood (2018) 132 (Supplement 1): 5092.

https://doi.org/10.1182/blood-2018-99-117499

Published: 2018

Journal Articles

A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice

Reema Jain, Julie M. Sheridan, Antonia Policheni, Melanie Heinlein, Luke C. Gandolfo, Grant Dewson, Gordon K. Smyth, Stephen N. Sansom, Nai Yang Fu, Jane E. Visvader, Georg A. Holländer, Andreas Strasser, Daniel H. D. Gray

Blood (2017) 130 (23): 2504–2515.

https://doi.org/10.1182/blood-2017-03-771576

Published: 2017

Includes: Supplemental data

Journal Articles

Alloreactive Natural Killer Cells Initiate a Unique Cellular and Molecular Pathway That Greatly Accelerates Immune Reconstitution after Allogeneic Bone Marrow Transplantation

Loredana Ruggeri, Elena Urbani, Davide Chiasserini, Federica Susta, Pierluigi Orvietani, Emanuela Burchielli, Dunia Ramarli, Luciano Binaglia, Connie Jimenez, Georg A. Hollander, Andrea Velardi

Blood (2016) 128 (22): 548.

https://doi.org/10.1182/blood.V128.22.548.548

Published: 2016

Journal Articles

Impaired thymic expression of tissue-restricted antigens licenses the de novo generation of autoreactive CD4 + T cells in acute GVHD

Simone Dertschnig, Mathias M. Hauri-Hohl, Madeleine Vollmer, Georg A. Holländer, Werner Krenger

Blood (2015) 125 (17): 2720–2723.

https://doi.org/10.1182/blood-2014-08-597245

Published: 2015

Includes: Supplemental data

Journal Articles

Epithelial cytoprotection sustains ectopic expression of tissue-restricted antigens in the thymus during murine acute GVHD

Simone Dertschnig, Gretel Nusspaumer, Robert Ivanek, Mathias M. Hauri-Hohl, Georg A. Holländer, Werner Krenger

Blood (2013) 122 (5): 837–841.

https://doi.org/10.1182/blood-2012-12-474759

Published: 2013

Includes: Supplemental data

Journal Articles

Thymic T-cell development in allogeneic stem cell transplantation

Werner Krenger, Bruce R. Blazar, Georg A. Holländer

Blood (2011) 117 (25): 6768–6776.

https://doi.org/10.1182/blood-2011-02-334623

Published: 2011

Journal Articles

Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation

Ryan M. Kelly, Emily M. Goren, Patricia A. Taylor, Scott N. Mueller, Heather E. Stefanski, Mark J. Osborn, Hamish S. Scott, Elena A. Komarova, Andrei V. Gudkov, Georg A. Holländer, Bruce R. Blazar

Blood (2010) 115 (5): 1088–1097.

https://doi.org/10.1182/blood-2009-05-223198

Published: 2010

Includes: Supplemental data

Journal Articles

Short-Term Inhibition of p53 Combined with Keratinocyte Growth Factor Improves Thymic Epithelial Cell Recovery and Enhances T-Cell Reconstitution After Murine Bone Marrow Transplantation.

Ryan Kelly, Emily Goren, Patricia Taylor, DVM, Hamish S Scott, Elena Komarova, Andrei Gudkov, Georg A. Hollander, MD, Bruce R. Blazar, MD

Blood (2009) 114 (22): 4485.

https://doi.org/10.1182/blood.V114.22.4485.4485

Published: 2009

Journal Articles

Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells

Lukas T. Jeker, Thomas Barthlott, Marcel P. Keller, Saulius Zuklys, Mathias Hauri-Hohl, Chu-Xia Deng, Georg A. Holländer

Blood (2008) 112 (9): 3688–3695.

https://doi.org/10.1182/blood-2008-04-150532

Published: 2008

Includes: Supplemental data

Journal Articles

TGF-β signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution

Mathias M. Hauri-Hohl, Saulius Zuklys, Marcel P. Keller, Lukas T. Jeker, Thomas Barthlott, Anne M. Moon, Jürgen Roes, Georg A. Holländer

Blood (2008) 112 (3): 626–634.

https://doi.org/10.1182/blood-2007-10-115618

Published: 2008

Includes: Supplemental data

Journal Articles

Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation

Ryan M. Kelly, Steven L. Highfill, Angela Panoskaltsis-Mortari, Patricia A. Taylor, Richard L. Boyd, Georg A. Holländer, Bruce R. Blazar

Blood (2008) 111 (12): 5734–5744.

https://doi.org/10.1182/blood-2008-01-136531

Published: 2008

Includes: Supplemental data

Journal Articles

Thymic stromal lymphopoietin is not necessary or sufficient to mediate the thymopoietic effects of keratinocyte growth factor

Martin Guimond, Warren J. Leonard, Rosanne Spolski, Simona W. Rossi, Rachelle G. Veenstra, Georg A. Hollander, Crystal L. Mackall, Bruce R. Blazar

Blood (2008) 111 (2): 969–970.

https://doi.org/10.1182/blood-2007-09-113316

Published: 2008

Journal Articles

Induction of Endogenous Repair Mechanisms by Single-Stranded DNA Oligonucleotide Therapy for Correction of the DNA-PK Mutation in Murine Severe Combined Immune Deficiency.

Jakub Tolar, MD, PhD, Angela Panoskaltsis-Mortari, Ph.D., Anton K. Yerich, B.S., Ron T. McElmurry, B.S., Georg A. Hollander, Betsy T. Kren, Ph.D., Clifford J. Steer, M.D., Bruce R. Blazar, M.D.

Blood (2006) 108 (11): 454.

https://doi.org/10.1182/blood.V108.11.454.454

Published: 2006

Journal Articles

Keratinocyte Growth Factor Increases Thymic Output of Naïve T-Cells after Total Body Irradiation and Autologous Peripheral Blood Progenitor Cell Transplantation in Rhesus Macaques.

Ruth Seggewiss, MD, Karin Lore, PhD, F. Javier Guenaga, BS, Stefania Pittaluga, MD, Joseph J. Matappallil, PhD, David Ambrozak, PhD, Robert T. Bailer, Richard A. Koup, MD, Robert E. Donahue, DVM, Bruce R. Blazar, MD, Georg A. Hollander, MD, Daniel C. Douek, PhD, Cynthia E. Dunbar, MD

Blood (2005) 106 (11): 187.

https://doi.org/10.1182/blood.V106.11.187.187

Published: 2005

Journal Articles

The role of CCL21 in recruitment of T-precursor cells to fetal thymi

Cunlan Liu, Tomoo Ueno, Sachiyo Kuse, Fumi Saito, Takeshi Nitta, Luca Piali, Hideki Nakano, Terutaka Kakiuchi, Martin Lipp, Georg A. Hollander, Yousuke Takahama

Blood (2005) 105 (1): 31–39.

https://doi.org/10.1182/blood-2004-04-1369

Published: 2005

Includes: Multimedia, Supplemental data

Journal Articles

Promoter IV of the class II transactivator gene is essential for positive selection of CD4 + T cells

Jean-Marc Waldburger, Simona Rossi, Georg A. Hollander, Hans-Reimer Rodewald, Walter Reith, Hans Acha-Orbea

Blood (2003) 101 (9): 3550–3559.

https://doi.org/10.1182/blood-2002-06-1855

Published: 2003

NARROW

Donor natural killer cells trigger production of β-2-microglobulin to enhance post–bone marrow transplant immunity

Engineering Regenerative Thymic Tissues to Restore Long-Term T Cell Lymphopoiesis

A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice

Alloreactive Natural Killer Cells Initiate a Unique Cellular and Molecular Pathway That Greatly Accelerates Immune Reconstitution after Allogeneic Bone Marrow Transplantation

Impaired thymic expression of tissue-restricted antigens licenses the de novo generation of autoreactive CD4 + T cells in acute GVHD

Epithelial cytoprotection sustains ectopic expression of tissue-restricted antigens in the thymus during murine acute GVHD

Thymic T-cell development in allogeneic stem cell transplantation

Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation

Short-Term Inhibition of p53 Combined with Keratinocyte Growth Factor Improves Thymic Epithelial Cell Recovery and Enhances T-Cell Reconstitution After Murine Bone Marrow Transplantation.

Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells

TGF-β signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution

Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation

Thymic stromal lymphopoietin is not necessary or sufficient to mediate the thymopoietic effects of keratinocyte growth factor

Induction of Endogenous Repair Mechanisms by Single-Stranded DNA Oligonucleotide Therapy for Correction of the DNA-PK Mutation in Murine Severe Combined Immune Deficiency.

Keratinocyte Growth Factor Increases Thymic Output of Naïve T-Cells after Total Body Irradiation and Autologous Peripheral Blood Progenitor Cell Transplantation in Rhesus Macaques.

The role of CCL21 in recruitment of T-precursor cells to fetal thymi

Promoter IV of the class II transactivator gene is essential for positive selection of CD4 + T cells

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American Society of Hematology

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American Society of Hematology

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