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Journal Articles

Nrf2 Null Mice Are Deficient in CD169 + Macrophages, Associated with Impaired Erythroid Response and Delayed Recovery from Acute Blood Loss

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Mark A Ross, Samit Ghosh, Frances Weidert, MS, Grant C. Bullock, MD PhD, Solomon Fiifi Ofori-Acquah, Gregory J Kato, MD, Simon Watkins

Blood (2019) 134 (Supplement_1): 1038.

https://doi.org/10.1182/blood-2019-127295

Published: 2019

Journal Articles

Macrophage Hypercellularity Accompanies Erythroid Hyperplasia in Sickle Cell Mice and during Recovery from Blood Loss in Wild Type Mice

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Samit Ghosh, Frances Weidert, MS, Grant C. Bullock, MD PhD, Solomon Fiifi Ofori-Acquah, Gregory J Kato, MD

Blood (2019) 134 (Supplement_1): 3528.

https://doi.org/10.1182/blood-2019-127224

Published: 2019

Journal Articles

Soluble Guanylate Cyclase Modulators Effect Fetal Hemoglobin Levels through a Non-cGMP-Protein Kinase G Signaling Pathway

Bin Sun, PhD, Valerie Miller, MS, Karin P Potoka, MD, Yukio Nakamura, MD PhD, Mark T Gladwin, MD, Grant C. Bullock, MD PhD

Blood (2018) 132 (Supplement 1): 1060.

https://doi.org/10.1182/blood-2018-99-120306

Published: 2018

Journal Articles

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Maria G Kapetanaki, PhD, Oluwabukola Gbotosho, BSc, MSc, PhD, Deva Sharma, MD MS, Schrott Valerie, MS, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Grant C. Bullock, MD PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3496.

https://doi.org/10.1182/blood.V130.Suppl_1.3496.3496

Published: 2017

Journal Articles

Aconitase: An Iron Sensing Regulator of Mitochondrial Oxidative Metabolism and Erythropoiesis

Naomi D Gunawardena, BS, Valerie Schrott, MS, Chanté Richardson, PhD, Teague Nolan Cole, BS, Catherine G Corey, BS, Yinna Wang, PhD, Sruti S Shiva, PhD, Grant C Bullock, MD PhD

Blood (2016) 128 (22): 74.

https://doi.org/10.1182/blood.V128.22.74.74

Published: 2016

Journal Articles

Regulation of the Erythroid Iron Deprivation Response By a TfR2-Scribble-Epor Integrated Module Coupling Iron Sensing with Receptor Presentation

Shadi Khalil, MS, Lorrie L Delehanty, BS, Maja Holy, BS, Stephen Grado, BS, Grant C. Bullock, MD PhD, Adam Goldfarb, MD

Blood (2016) 128 (22): 3615.

https://doi.org/10.1182/blood.V128.22.3615.3615

Published: 2016

Journal Articles

The Role of Mitochondrial Metabolism and Redox Signaling in Iron Deficiency Anemia

Grant C Bullock, MD PhD, Chanté L Richardson, MS, PhD, Valerie Schrott, MS, Naomi D Gunawardena, BS, Teague Nolan Cole, BS, Catherine G Corey, BS, Sruti S Shiva, PhD

Blood (2015) 126 (23): 2145.

https://doi.org/10.1182/blood.V126.23.2145.2145

Published: 2015

Journal Articles

The Oxidant Response Transcription Factor NRF2 Mediates Heme Activation of Placenta Growth Factor Expression in Erythroid Cells, a Contributor to Pulmonary Hypertension in Sickle Cell Disease

Maria G Kapetanaki, PhD, Deva Sharma, MD MS, Oluwabukola T Gbotosho, PhD, Valerie Schrott, MS, Frances Weidart, BS, Solomon Fiifi Ofori-Acquah, PhD, Grant C Bullock, MD PhD, Gregory J. Kato, MD

Blood (2015) 126 (23): 403.

https://doi.org/10.1182/blood.V126.23.403.403

Published: 2015

Journal Articles

Thrombospondin-1 Stimulates Calcium Influx and Echinocytosis in Sickle Cell-Derived Red Blood Cells

Tamir Kanias, PhD, Jeffrey Isenberg, MD MPH, Grant C Bullock, MD PhD, Valerie M Schrott, MS, Donna B Stolz, PhD, Enrico M Novelli, MD MS

Blood (2014) 124 (21): 4068.

https://doi.org/10.1182/blood.V124.21.4068.4068

Published: 2014

Journal Articles

Role of Iron-Responsive Mitochondrial Metabolism and ROS in Anemia

Chanté L Richardson, MS, PhD, Valerie M Schrott, MS, Claudette M St. Croix, PhD, Yinna Wang, MD PhD, Catherine G Corey, BS, Sruti Shiva, PhD, Grant C Bullock, MD PhD

Blood (2014) 124 (21): 216.

https://doi.org/10.1182/blood.V124.21.216.216

Published: 2014

Journal Articles

Mitochondrial Uncoupling Protein 2 Is Present in Human Platelets and Regulates Platelet Activation

Sruti Shiva, PhD, Enrico M Novelli, MD MS, Grant C Bullock, MD PhD, Elizabeth Kenny, Gabrielle Hill, Catherine G Corey, BS

Blood (2014) 124 (21): 4147.

https://doi.org/10.1182/blood.V124.21.4147.4147

Published: 2014

Journal Articles

Regulatory Role Of Mitochondrial Aconitase and Isocitrate In Iron-Responsive, Erythropoietin Receptor Signaling During Anemia

Grant C Bullock, M.D., Ph.D., Valerie Schrott, MS

Blood (2013) 122 (21): 3443.

https://doi.org/10.1182/blood.V122.21.3443.3443

Published: 2013

Journal Articles

Protein kinase D-HDAC5 signaling regulates erythropoiesis and contributes to erythropoietin cross-talk with GATA1

Lorrie L. Delehanty, Grant C. Bullock, Adam N. Goldfarb

Blood (2012) 120 (20): 4219–4228.

https://doi.org/10.1182/blood-2011-10-387050

Published: 2012

Includes: Supplemental data

Journal Articles

The Role of the Distal Erythropoietin Receptor in Iron Deficiency Anemia

Grant C. Bullock, MD, PhD, Lorrie L. Delehanty, Anne-Laure A Talbot, Chante Richardson, Adam Goldfarb, MD

Blood (2011) 118 (21): 1312.

https://doi.org/10.1182/blood.V118.21.1312.1312

Published: 2011

Journal Articles

Manipulating the Erythroid Iron Deprivation Response Affects Inflammatory Signaling in Anemia of Chronic Inflammation

Chanté L. Richardson, Grant C. Bullock, MD, PhD, Lorrie L. Delehanty, Claudia Rival, Kenneth Tung, Adam Goldfarb

Blood (2011) 118 (21): 179.

https://doi.org/10.1182/blood.V118.21.179.179

Published: 2011

Journal Articles

Targeting the Erythroid Iron Deprivation Response as a Therapeutic Approach In Anemia Not Caused by Iron Deficiency

Chanté L. Richardson, Grant C. Bullock, Lorrie L. Delehanty, Adam N. Goldfarb

Blood (2010) 116 (21): 166.

https://doi.org/10.1182/blood.V116.21.166.166

Published: 2010

Journal Articles

RSK Inhibition Rescues Defective Erythropoiesis Caused by Blockade of Mitochondrial Aconitase

Anne-Laure Talbot, Grant C. Bullock, Lorrie Delehanty, Adam Goldfarb, MD

Blood (2010) 116 (21): 1008.

https://doi.org/10.1182/blood.V116.21.1008.1008

Published: 2010

Journal Articles

Iron control of erythroid development by a novel aconitase-associated regulatory pathway

Grant C. Bullock, Lorrie L. Delehanty, Anne-Laure Talbot, Sara L. Gonias, Wing-Hang Tong, Tracey A. Rouault, Brian Dewar, Jeffrey M. Macdonald, Jason J. Chruma, Adam N. Goldfarb

Blood (2010) 116 (1): 97–108.

https://doi.org/10.1182/blood-2009-10-251496

Published: 2010

Includes: Supplemental data

Journal Articles

Synergy Between Specific Inflammatory Cytokines, IFNγ and TNFα, and Iron Restriction in Erythroid Blockade: A New Model for Anemia of Chronic Disease.

Chante Richardson, Grant C. Bullock, MD, PhD, Lorrie L Delehanty, Anne-Laure Talbot, Kamaleldin E Elagib, Jeremy Rubinstein, Adam Goldfarb, MD

Blood (2009) 114 (22): 159.

https://doi.org/10.1182/blood.V114.22.159.159

Published: 2009

Journal Articles

Aconitase Modulates Erythroid Signaling through a Novel MEK-ERK Regulatory Pathway.

Anne-Laure Talbot, Grant C. Bullock, MD, PhD, Lorrie L Delehanty, Adam Goldfarb, MD

Blood (2009) 114 (22): 75.

https://doi.org/10.1182/blood.V114.22.75.75

Published: 2009

NARROW

Nrf2 Null Mice Are Deficient in CD169 + Macrophages, Associated with Impaired Erythroid Response and Delayed Recovery from Acute Blood Loss

Macrophage Hypercellularity Accompanies Erythroid Hyperplasia in Sickle Cell Mice and during Recovery from Blood Loss in Wild Type Mice

Soluble Guanylate Cyclase Modulators Effect Fetal Hemoglobin Levels through a Non-cGMP-Protein Kinase G Signaling Pathway

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Aconitase: An Iron Sensing Regulator of Mitochondrial Oxidative Metabolism and Erythropoiesis

Regulation of the Erythroid Iron Deprivation Response By a TfR2-Scribble-Epor Integrated Module Coupling Iron Sensing with Receptor Presentation

The Role of Mitochondrial Metabolism and Redox Signaling in Iron Deficiency Anemia

The Oxidant Response Transcription Factor NRF2 Mediates Heme Activation of Placenta Growth Factor Expression in Erythroid Cells, a Contributor to Pulmonary Hypertension in Sickle Cell Disease

Thrombospondin-1 Stimulates Calcium Influx and Echinocytosis in Sickle Cell-Derived Red Blood Cells

Role of Iron-Responsive Mitochondrial Metabolism and ROS in Anemia

Mitochondrial Uncoupling Protein 2 Is Present in Human Platelets and Regulates Platelet Activation

Regulatory Role Of Mitochondrial Aconitase and Isocitrate In Iron-Responsive, Erythropoietin Receptor Signaling During Anemia

Protein kinase D-HDAC5 signaling regulates erythropoiesis and contributes to erythropoietin cross-talk with GATA1

The Role of the Distal Erythropoietin Receptor in Iron Deficiency Anemia

Manipulating the Erythroid Iron Deprivation Response Affects Inflammatory Signaling in Anemia of Chronic Inflammation

Targeting the Erythroid Iron Deprivation Response as a Therapeutic Approach In Anemia Not Caused by Iron Deficiency

RSK Inhibition Rescues Defective Erythropoiesis Caused by Blockade of Mitochondrial Aconitase

Iron control of erythroid development by a novel aconitase-associated regulatory pathway

Synergy Between Specific Inflammatory Cytokines, IFNγ and TNFα, and Iron Restriction in Erythroid Blockade: A New Model for Anemia of Chronic Disease.

Aconitase Modulates Erythroid Signaling through a Novel MEK-ERK Regulatory Pathway.

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American Society of Hematology

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American Society of Hematology

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