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Helena Jernberg Wiklund
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Journal Articles

An Epigenomic Map of Multiple Myeloma Reveals the Importance of Polycomb Gene Silencing for the Malignancy

Prasoon Agarwal, Antonia Kalushkova, PhD, Stefan Enroth, PhD, Mohammad Alzrigat, Anders Österborg, Kenneth Nilsson, MD PhD, Fredrik Öberg, PhD, Helena Jernberg-Wiklund, PhD
Journal: Blood
Blood (2014) 124 (21): 2192.
https://doi.org/10.1182/blood.V124.21.2192.2192
Published: 2014
Journal Articles

Recurrent Mutations within the Nfkbie gene: A Novel Mechanism for NF-κB Deregulation in Aggressive Chronic Lymphocytic Leukemia

Larry Mansouri, Lesley-Ann Sutton, Viktor Ljungstrom, Sina Bondza, Linda Arngarden, Sujata Bhoi, Jimmy Larsson, Diego Cortese, Antonia Kalushkova, PhD, Rebeqa Gunnarsson, Emma Young, Elin Falk-Sorqvist, Karla Plevova, Alice Muggen, Xiao-Jie Yan, MD PhD, Birgitta Sander, MD PhD, Gunilla Enblad, MD PhD, Karin E Smedby, MD PhD, Gunnar Juliusson, MD PhD, Chrysoula Belessi, Nicholas Chiorazzi, MD, Jonathan C Strefford, Anton W Langerak, Sarka Pospisilova, Frederic Davi, MD PhD, Mats Hellstrom, Helena Jernberg Wiklund, PhD, Paolo Ghia, MD PhD, Ola Soderberg, Kostas Stamatopoulos, Mats Nilsson, Richard Rosenquist
Journal: Blood
Blood (2014) 124 (21): 297.
https://doi.org/10.1182/blood.V124.21.297.297
Published: 2014
Journal Articles

The DNA Methyltransferase Inhibitor Decitabine Induces DNA Damage, Cell Cycle Arrest and Apoptosis in Multiple Myeloma

Ken Maes, Miguel Lemaire, Jordan Gauthier, Hendrik De Raeve, Eline Menu, PhD, Els Van Valckenborgh, PhD, Helena Jernberg Wiklund, PhD, Karin Vanderkerken, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2012) 120 (21): 1833.
https://doi.org/10.1182/blood.V120.21.1833.1833
Published: 2012
Journal Articles

Combination of the IGF-1 Receptor Inhibitor Picropodophylin and the BH3 Mimetic ABT-737 Has Synergistic Anti-Myeloma Activity

Liesbeth Bieghs, Ken Maes, Els Van Valckenborgh, PhD, Eline Menu, PhD, Hans Erik Johnsen, Mette Nyegaard, PhD, Helena Jernberg Wiklund, PhD, Karin Vanderkerken, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2012) 120 (21): 4010.
https://doi.org/10.1182/blood.V120.21.4010.4010
Published: 2012
Journal Articles

ABT-737 Sensitizes B Cell Tumors for Killing by CD19-Retargeted T Cells,

Hannah S C Karlsson, Camilla Lindqvist, PhD, Gabriella Paul-Wetterberg, Helena Jernberg Wiklund, PhD, Kenneth Nilsson, MD, PhD, Bengt Simonsson, MD, PhD, Per Frisk, MD, PhD, Angelica Loskog, PhD
Journal: Blood
Blood (2011) 118 (21): 4032.
https://doi.org/10.1182/blood.V118.21.4032.4032
Published: 2011
Journal Articles

IGF-1 suppresses Bim expression in multiple myeloma via epigenetic and posttranslational mechanisms

Elke De Bruyne, Tomas J. Bos, Frans Schuit, Els Van Valckenborgh, Eline Menu, Lieven Thorrez, Peter Atadja, Helena Jernberg-Wiklund, Karin Vanderkerken
Journal: Blood
Blood (2010) 115 (12): 2430–2440.
https://doi.org/10.1182/blood-2009-07-232801
Published: 2010
Includes: Supplemental data
Journal Articles

Selective Inhibition of Glycogen Synthase Kinase-3 by Facilitators of Insulin Response Promotes Proliferation and Survival in Multiple Myeloma Cells.

Helena Jernberg-Wiklund, PhD, Thomas Stromberg, PhD, Anna Hammarberg, Patrik Georgii-Hemming, MD, PhD, Anders Osterborg, MD, PhD, Kenneth Nilsson, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 4789.
https://doi.org/10.1182/blood.V110.11.4789.4789
Published: 2007
Journal Articles

Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model

Eline Menu, Helena Jernberg-Wiklund, Thomas Stromberg, Hendrik De Raeve, Leonard Girnita, Olle Larsson, Magnus Axelson, Kewal Asosingh, Kenneth Nilsson, Ben Van Camp, Karin Vanderkerken
Journal: Blood
Blood (2006) 107 (2): 655–660.
https://doi.org/10.1182/blood-2005-01-0293
Published: 2006
Journal Articles

IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G 2 /M-phase accumulation and apoptosis in multiple myeloma cells

Thomas Strömberg, Simon Ekman, Leonard Girnita, Lina Y. Dimberg, Olle Larsson, Magnus Axelson, Johan Lennartsson, Ulf Hellman, Kristina Carlson, Anders Österborg, Karin Vanderkerken, Kenneth Nilsson, Helena Jernberg-Wiklund
Journal: Blood
Blood (2006) 107 (2): 669–678.
https://doi.org/10.1182/blood-2005-01-0306
Published: 2006
Includes: Supplemental data
Journal Articles

Expression of Erythropoietin Receptor (EPO-R) and In Vitro Functional Effects of Epoetin in B-Cell Malignancies.

Amir Abdalla, Parviz Kokhaei, Lotta Hansson, Manfred Kubbies, Anton Haselbeck, Eva Mikaelsson, Helena Jernberg-Wiklund, Håkan Mellstedt, Anders Österborg Österborg
Journal: Blood
Blood (2005) 106 (11): 4278.
https://doi.org/10.1182/blood.V106.11.4278.4278
Published: 2005
Journal Articles

Ectopic and IFN-induced expression of Fas overcomes resistance to Fas-mediated apoptosis in multiple myeloma cells

Lina Y. Dimberg, Anna I. Dimberg, Karolina Ivarsson, Thomas Strömberg, Anders Österborg, Kenneth Nilsson, Fredrik Öberg, Helena Jernberg Wiklund
Journal: Blood
Blood (2005) 106 (4): 1346–1354.
https://doi.org/10.1182/blood-2004-04-1322
Published: 2005
Includes: Supplemental data
Journal Articles

Toward a rational combinaTORial therapy for multiple myeloma

Helena Jernberg-Wiklund, Kenneth Nilsson
Journal: Blood
Blood (2004) 104 (13): 3845–3846.
https://doi.org/10.1182/blood-2004-09-3648
Published: 2004
Journal Articles

Targeting the Insulin-Like Growth Factor-I Receptor (IGF-IR) in Multiple Myeloma Cells Using Selective IGF-IR Tyrosine Kinase Inhibitors.

Thomas Stromberg, PhD, Simon Ekman, MD, PhD, Leonard Girnita, PhD, Johan Lennartsson, Ulf Hellman, PhD, Kristina Carlson, MD, PhD, Anders Osterborg, MD, PhD, Karin Vanderkerken, PhD, Magnus Axelson, MD, PhD, Olle Larsson, MD, PhD, Kenneth Nilsson, MD, PhD, Helena Jernberg-Wiklund, PhD
Journal: Blood
Blood (2004) 104 (11): 639.
https://doi.org/10.1182/blood.V104.11.639.639
Published: 2004
Journal Articles

Inhibiting the IGF-1 Receptor Tyrosine Kinase with Picropodophillin: An In Vitro and In Vivo Study in the 5T33MM Mouse Model.

Karin Vanderkerken, PhD, Eline Menu, Thomas Stromberg, PhD, Hendrik De Raeve, MD, Kewal Asosingh, PhD, Ben Van Camp, MD, PhD, Helena Jernberg-Wiklund, PhD
Journal: Blood
Blood (2004) 104 (11): 640.
https://doi.org/10.1182/blood.V104.11.640.640
Published: 2004
Journal Articles

Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone

Thomas Strömberg, Anna Dimberg, Anna Hammarberg, Kristina Carlson, Anders Österborg, Kenneth Nilsson, Helena Jernberg-Wiklund
Journal: Blood
Blood (2004) 103 (8): 3138–3147.
https://doi.org/10.1182/blood-2003-05-1543
Published: 2004
Journal Articles

The Somatostatin Analog Octreotide Inhibits Growth of Interleukin-6 (IL-6)–Dependent and IL-6–Independent Human Multiple Myeloma Cell Lines

Patrik Georgii-Hemming, Thomas Strömberg, Eva Tiensuu Janson, Mats Stridsberg, Helena Jernberg Wiklund, Kenneth Nilsson
Journal: Blood
Blood (1999) 93 (5): 1724–1731.
https://doi.org/10.1182/blood.V93.5.1724
Published: 1999
Journal Articles

Fas/APO-1 (CD95)–Mediated Apoptosis Is Activated by Interferon-γ and Interferon- in Interleukin-6 (IL-6)–Dependent and IL-6–Independent Multiple Myeloma Cell Lines

Helena Spets, Patrik Georgii-Hemming, Jan Siljason, Kenneth Nilsson, Helena Jernberg-Wiklund
Journal: Blood
Blood (1998) 92 (8): 2914–2923.
https://doi.org/10.1182/blood.V92.8.2914
Published: 1998