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Journal Articles

Survival Advantage Associated with Heterozygous Factor V Leiden Mutation in Sars-Cov-2-Infected K18-hACE2 Mice

Roberto Aiolfi, Jose A. Fernandez, Hiroshi Deguchi, Xiao Xu, Jeanine Ahmed, Miriam Hauer-Jensen, John H. Griffin, Juan Carlos de la Torre, Hartmut Weiler, Laurent O. Mosnier

Blood (2023) 142 (Supplement 1): 2563.

https://doi.org/10.1182/blood-2023-190742

Published: 2023

Journal Articles

Sex-Specific Differences in the Pathogenesis, Endothelial Dysfunction, and Hypercoagulability of Sars-Cov-2 Infection in K18-hACE2 Mice

Roberto Aiolfi, Hiroshi Deguchi, Jose F. Fernández, Jeanine Ahmed, Miriam Hauer-Jensen, Juan Carlos de la Torre, Laurent O. Mosnier

Blood (2022) 140 (Supplement 1): 1674–1675.

https://doi.org/10.1182/blood-2022-163863

Published: 2022

Journal Articles

Skeletal Muscle Myosin Is Procoagulant By Binding Factor XI Via Its A3 Domain and Enhancing Factor XI Activation By Thrombin

Hiroshi Deguchi, Shravan Morla, Jevgenia Zilberman-Rudenko, Andras Gruber, Owen J T McCarty, Priyanka Srivastava, David Gailani, John H. Griffin

Blood (2021) 138 (Supplement 1): 441.

https://doi.org/10.1182/blood-2021-151372

Published: 2021

Journal Articles

Procoagulant activities of skeletal muscle and cardiac myosins require both myosin protein and myosin-associated anionic phospholipids

Shravan Morla, Hiroshi Deguchi, José A. Fernández, Wolfram Ruf, Rolf A. Brekken, John H. Griffin

Blood (2021) 137 (13): 1839–1842.

https://doi.org/10.1182/blood.2020008580

Published: 2021

Journal Articles

Procoagulant Activity of Skeletal Muscle Myosin Is Not Caused By Contaminating Phosphatidylserine-Vesicles

Shravan Morla, Hiroshi Deguchi, MD PhD, Rolf Brekken, PhD, John H. Griffin, PhD

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-139574

Published: 2020

Journal Articles

Molecular Interaction Site on Procoagulant Skeletal Muscle Myosin for Factor Xa-Dependent Prothrombin Activation

Hiroshi Deguchi, MD PhD, Zihan Guo, Mohammed Hayat, Elsa Pflimlin, Weijun Shen, John H. Griffin, PhD

Blood (2019) 134 (Supplement_1): 3622.

https://doi.org/10.1182/blood-2019-129161

Published: 2019

Journal Articles

Cardiac Myosin Acts Is a Potent Procoagulant in Vitro and In Vivo

Jevgenia Zilberman-Rudenko, Hiroshi Deguchi, MD PhD, Mohammed Hayat, Meenal Shukla, PhD, Jennifer Nagrampa Orje, Zihan Guo, Tine Wyseure, PhD, Laurent O Mosnier, Owen J T McCarty, PhD, Zaverio M. Ruggeri, MD, John H. Griffin, PhD

Blood (2019) 134 (Supplement_1): 3632.

https://doi.org/10.1182/blood-2019-129312

Published: 2019

Journal Articles

Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va

Hiroshi Deguchi, Ranjeet K. Sinha, Patrizia Marchese, Zaverio M. Ruggeri, Jevgenia Zilberman-Rudenko, Owen J. T. McCarty, Mitchell J. Cohen, John H. Griffin

Blood (2016) 128 (14): 1870–1878.

https://doi.org/10.1182/blood-2016-03-707679

Published: 2016

Includes: Supplemental data

Journal Articles

Exome Genotyping Links Venous Thrombosis Risk with the Skeletal Muscle Myosin Gene Cluster and Leads to Discovery of New Family of Procoagulant Factors

Hiroshi Deguchi, MD PhD, Ranjeet Kumar Sinha, PhD MSc, Darlene J. Elias, MD, John H. Griffin, PhD

Blood (2015) 126 (23): 763.

https://doi.org/10.1182/blood.V126.23.763.763

Published: 2015

Journal Articles

Plasma Constitutive Serum Amyloid A4 Is Procoagulant and Is Elevated in Venous Thrombosis Patients

John H. Griffin, PhD, Jose A. Fernandez, MD PhD, Ranjeet Kumar Sinha, PhD MSc, Darlene J. Elias, MD, Hiroshi Deguchi, MD PhD

Blood (2015) 126 (23): 3486.

https://doi.org/10.1182/blood.V126.23.3486.3486

Published: 2015

Journal Articles

Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data

Hiroshi Deguchi, Yajnavalka Banerjee, Sunia Trauger, Gary Siuzdak, Ewa Kalisiak, José A. Fernández, Linh Hoang, Minerva Tran, Subramanian Yegneswaran, Darlene J. Elias, John H. Griffin

Blood (2015) 126 (13): 1595–1600.

https://doi.org/10.1182/blood-2015-03-636761

Published: 2015

Includes: Supplemental data

Journal Articles

Acylcarnitines Are Novel Anticoagulant Lipids That Target Factor Xa and That Are Reduced in Plasma of Venous Thrombosis Patients Based on Untargeted and Targeted Metabolomics

Hiroshi Deguchi, MD PhD, Yajnavalka Banerjee, PhD, Gary Siuzdak, PhD, Sunia Trauger, PhD, Ewa Kalisiak, PhD, Jose A. Fernandez, MD PhD, Linh Hoang, Minerva Tran, Subramanian Yegneswaran, PhD, Darlene J Elias, MD, John H. Griffin, PhD

Blood (2014) 124 (21): 2797.

https://doi.org/10.1182/blood.V124.21.2797.2797

Published: 2014

Journal Articles

Plasma High Density Lipoprotein and Anticoagulant Response to Activated Protein C (APC) and Protein S

Jose A. Fernandez, MD, PhD, Hiroshi Deguchi, MD, PhD, Natalie M Pecheniuk, Ph.D., Subramanian Yegneswaran, PhD, Carole L Banka, Ph. D., John H. Griffin, PhD

Blood (2011) 118 (21): 2249.

https://doi.org/10.1182/blood.V118.21.2249.2249

Published: 2011

Journal Articles

Warfarin Untargeted Metabolomics Study Identifies Novel Procoagulant Ethanolamide Lipids

Hiroshi Deguchi, MD, PhD, Sunia Trauger, PhD, Ewa Kalisiak, PhD, Hui-Min Zhang, PhD, Gary Siuzdak, PhD, John H. Griffin, PhD, Darlene J Elias, MD

Blood (2011) 118 (21): 1200.

https://doi.org/10.1182/blood.V118.21.1200.1200

Published: 2011

Journal Articles

Plasma Serum Amyloid A Levels Are Increased In Venous Thrombosis Patients and Are Correlated with Blood Coagulability

Hiroshi Deguchi, MD, PhD, Darlene J Elias, MD, Silvia Navarro, PhD, Francisco Espana, PhD, John H. Griffin, PhD

Blood (2010) 116 (21): 155.

https://doi.org/10.1182/blood.V116.21.155.155

Published: 2010

Journal Articles

Lyso-Sulfatide Binds Factor Xa and Potently Inhibits Thrombin Generation.

Subramanian Yegneswaran, PhD, Yajnavalka Banerjee, PhD, Jose A. Fernandez, MD, PhD, Hiroshi Deguchi, MD, PhD, John H. Griffin, PhD

Blood (2010) 116 (21): 1130.

https://doi.org/10.1182/blood.V116.21.1130.1130

Published: 2010

Journal Articles

Activation of the PI3K-Akt Pathway by Activated Protein C Occurs Via a Novel Receptor, Apolipoprotein E Receptor 2 (ApoER2)

Xia V. Yang, PhD, Yajnavalka Banerjee, PhD, Jose A. Fernandez, MD, PhD, Hiroshi Deguchi, MD, PhD, Xiao Xu, Laurent O. Mosnier, PhD, Rolf T Urbanus, MD, Phillip G deGroot, PhD, Tara C White, Owen J.T. McCarty, PhD, John H. Griffin, PhD

Blood (2008) 112 (11): 695.

https://doi.org/10.1182/blood.V112.11.695.695

Published: 2008

Journal Articles

Risk of Recurrent Venous Thromboembolism Reduced by High Density Lipoproteins.

Sabine Eichinger, MD, Natalie M. Pecheniuk, Ph.D., Gregor Hron, M.D., Hiroshi Deguchi, M.D., Ph.D., Paul A. Kyrle, M.D., John H. Griffin, Ph.D.

Blood (2006) 108 (11): 271.

https://doi.org/10.1182/blood.V108.11.271.271

Published: 2006

Journal Articles

Plasma glucosylceramide deficiency as potential risk factor for venous thrombosis and modulator of anticoagulant protein C pathway

Hiroshi Deguchi, JoséA. Fernández, Ingrid Pabinger, John A. Heit, John H. Griffin

Blood (2001) 97 (7): 1907–1914.

https://doi.org/10.1182/blood.V97.7.1907

Published: 2001

Journal Articles

Dilazep, an Antiplatelet Agent, Inhibits Tissue Factor Expression in Endothelial Cells and Monocytes

Hiroshi Deguchi, Hiroyuki Takeya, Hideo Wada, Esteban C. Gabazza, Nobuyuki Hayashi, Hajime Urano, Koji Suzuki

Blood (1997) 90 (6): 2345–2356.

https://doi.org/10.1182/blood.V90.6.2345

Published: 1997

NARROW

Survival Advantage Associated with Heterozygous Factor V Leiden Mutation in Sars-Cov-2-Infected K18-hACE2 Mice

Sex-Specific Differences in the Pathogenesis, Endothelial Dysfunction, and Hypercoagulability of Sars-Cov-2 Infection in K18-hACE2 Mice

Skeletal Muscle Myosin Is Procoagulant By Binding Factor XI Via Its A3 Domain and Enhancing Factor XI Activation By Thrombin

Procoagulant activities of skeletal muscle and cardiac myosins require both myosin protein and myosin-associated anionic phospholipids

Procoagulant Activity of Skeletal Muscle Myosin Is Not Caused By Contaminating Phosphatidylserine-Vesicles

Molecular Interaction Site on Procoagulant Skeletal Muscle Myosin for Factor Xa-Dependent Prothrombin Activation

Cardiac Myosin Acts Is a Potent Procoagulant in Vitro and In Vivo

Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va

Exome Genotyping Links Venous Thrombosis Risk with the Skeletal Muscle Myosin Gene Cluster and Leads to Discovery of New Family of Procoagulant Factors

Plasma Constitutive Serum Amyloid A4 Is Procoagulant and Is Elevated in Venous Thrombosis Patients

Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data

Acylcarnitines Are Novel Anticoagulant Lipids That Target Factor Xa and That Are Reduced in Plasma of Venous Thrombosis Patients Based on Untargeted and Targeted Metabolomics

Plasma High Density Lipoprotein and Anticoagulant Response to Activated Protein C (APC) and Protein S

Warfarin Untargeted Metabolomics Study Identifies Novel Procoagulant Ethanolamide Lipids

Plasma Serum Amyloid A Levels Are Increased In Venous Thrombosis Patients and Are Correlated with Blood Coagulability

Lyso-Sulfatide Binds Factor Xa and Potently Inhibits Thrombin Generation.

Activation of the PI3K-Akt Pathway by Activated Protein C Occurs Via a Novel Receptor, Apolipoprotein E Receptor 2 (ApoER2)

Risk of Recurrent Venous Thromboembolism Reduced by High Density Lipoproteins.

Plasma glucosylceramide deficiency as potential risk factor for venous thrombosis and modulator of anticoagulant protein C pathway

Dilazep, an Antiplatelet Agent, Inhibits Tissue Factor Expression in Endothelial Cells and Monocytes

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American Society of Hematology

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ASH Publications

American Society of Hematology

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