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Journal Articles

Nrf2 sensitizes ferroptosis through l-2-hydroxyglutarate–mediated chromatin modifications in sickle cell disease

Caixia Xi, Junfeng Pang, Wenbo Zhi, Chang-Sheng S. Chang, Umapathy Siddaramappa, Huidong Shi, Anatoli Horuzsko, Betty S. Pace, Xingguo Zhu

Blood (2023) 142 (4): 382–396.

https://doi.org/10.1182/blood.2022018159

Published: 2023

Includes: Supplemental data

Journal Articles

Incremental Clinically Relevant Information in 70 CLL Cases with Optical Genome Mapping: Going Beyond Karyotype and FISH

Nikhil Sahajpal, Anand P. Jillella, Ashis Mondal, Harmanpreet Singh, Ashutosh Vashisht, Huidong Shi, Vamsi K. Kota, Ravindra Kolhe

Blood (2022) 140 (Supplement 1): 12361–12362.

https://doi.org/10.1182/blood-2022-168454

Published: 2022

Journal Articles

Transcriptome Sequencing Reveals Alternative Splicing Patterns and an Increased Sensitivity to Spliceosome Inhibition Associated MYD88 L265P Mutation in Chronic Lymphocytic Leukemia

Shuchao Qin, PhD, Xinyu Zhang, MBBS, Qimei Han, MBBS, Chang-Sheng Chang, PhD, Eun-Jeong Park, PhD, Lirong Pei, PhD, Chandraiah Lagisetti, PhD, Thomas R Webb, PhD, Jiazhu Wu, MD, Wei Xu, MD PhD, Jianyong Li, MD PhD, Huidong Shi, PhD

Blood (2018) 132 (Supplement 1): 5535.

https://doi.org/10.1182/blood-2018-99-118667

Published: 2018

Journal Articles

Indoximod Combined with Standard Induction Chemotherapy Is Well Tolerated and Induces a High Rate of Complete Remission with MRD-Negativity in Patients with Newly Diagnosed AML: Results from a Phase 1 Trial

Ashkan Emadi, MD PhD, Vu H. Duong, MD, Jeremy Pantin, MD, Mohammad Imran, MD, Rima Koka, MD PhD, Zeba Singh, MBBS, Edward A. Sausville, MD PhD, Jennie Y. Law, MD, Seung Tae Lee, MD PhD, Huidong Shi, PhD, Ravindra Kolhe, MD PhD, Maria R. Baer, MD, Michael R. Loken, PhD, Eugene P. Kennedy, MD, Charles Link, MD, David H. Munn, MD

Blood (2018) 132 (Supplement 1): 332.

https://doi.org/10.1182/blood-2018-99-117433

Published: 2018

Journal Articles

SF3B1 Mutation Causes Aberrant Splicing and Downregulation of PPP2R5A in Chronic Lymphocytic Leukemia

Qimei Han, MBBS, Libin Deng, PhD, Lirong Pei, Jeong-Hyeon Choi, PhD, Victor Jin, PhD, Huidong Shi

Blood (2017) 130 (Supplement 1): 2477.

https://doi.org/10.1182/blood.V130.Suppl_1.2477.2477

Published: 2017

Journal Articles

CDK7 Inhibitor THZ1 Inhibits Glycolytic Metabolism By Suppressing HIF1α Activity in Chronic Lymphocytic Leukemia

Shuchao Qin, MBBS, Austin Young Shull, Qimei Han, MBBS, Lirong Pei, Farrukh T. Awan, MD MS, Wei Xu, Jianyong Li, MD PhD, Huidong Shi

Blood (2017) 130 (Supplement 1): 3811.

https://doi.org/10.1182/blood.V130.Suppl_1.3811.3811

Published: 2017

Journal Articles

DNA Hypomethylation within B-Cell Enhancers and Super Enhancers Reveal a Dependency on Immune and Metabolic Mechanisms in Chronic Lymphocytic Leukemia

Austin Y. Shull, PhD, Junfeng Luo, PhD, Lirong Pei, Eun-Joon Lee, PhD, Jimei Liu, PhD, Justin Choi, PhD, Farrukh T. Awan, Huidong Shi, PhD

Blood (2016) 128 (22): 1049.

https://doi.org/10.1182/blood.V128.22.1049.1049

Published: 2016

Journal Articles

Heat Shock Factor 1 Promotes NF-Kb and B-Cell Signaling in a Preclinical Model of Chronic Lymphocytic Leukemia

Rekha Rao, PhD, Trisha Home, M.S, Abdulraheem Yacoub, MD, Huidong Shi, PhD, Ashok Saluja, PhD, Joseph McGuirk, DO, Siddhartha Ganguly, MD

Blood (2015) 126 (23): 5297.

https://doi.org/10.1182/blood.V126.23.5297.5297

Published: 2015

Journal Articles

Genome-Wide DNA Methylation Analysis Identifies Aberrant Epigenetic Changes in CD8+ T Cells from Chronic Lymphocytic Leukemia Patients

Jiazhu Wu, B. S., Xiaojing Xu, PhD, Lirong Pei, B.S., Eun-Joon Lee, PhD, Austin Shull, B.S., Farrukh Awan, MD MS, Xiaoling Wang, PhD, Lei Fan, MD, PhD, Li Jianyong, MD PhD, Xu Wei, MD PhD, Huidong Shi, PhD

Blood (2014) 124 (21): 3552.

https://doi.org/10.1182/blood.V124.21.3552.3552

Published: 2014

Journal Articles

DNA Hypomethylation Leads to Aberrant Expression of PD-1 in Chronic Lymphocytic Leukemia

Eun Joon Lee, Ph.D., Jimei Liu, Ph.D., Ethan Speir, James Wilson, B.S., Hena Joshi, B.S., Lirong Pei, B.S., Junfeng Luo, Ph.D., Farrukh Awan, M.D., M.S., David Munn, M.D., Xiao-Jie Yan, M.D., Ph.D., Nicholas Chiorazzi, MD, Huidong Shi, Ph.D.

Blood (2012) 120 (21): 3504.

https://doi.org/10.1182/blood.V120.21.3504.3504

Published: 2012

Journal Articles

Genome-Wide DNA Methylation Landscape Defines IGHV Mutated and Unmutated B Cell Chronic Lymphocytic Leukemias

Junfeng Luo, Ph.D., Justin Choi, Ph.D., Lirong Pei, B.S., Farrukh Awan, M.D., M.S., Eun-Joon Lee, Ph.D., Jimei Liu, Ph.D., Austin Shull, B.S., Brian A. McCarthy, Ph.D., James M. Wilson, B.S., Kristen H. Taylor, Ph.D., Xinguo Wang, Ph.D., Phillip Joe Buckhaults, Ph.D., David H. Munn, M.D., Charles W. Caldwell, M.D., Ph.D., Xiao-Jie Yan, M.D., Ph.D., Nicholas Chiorazzi, MD, Huidong Shi, Ph.D.

Blood (2012) 120 (21): 526.

https://doi.org/10.1182/blood.V120.21.526.526

Published: 2012

Journal Articles

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

Warren Fiskus, Yongchao Wang, Arun Sreekumar, Kathleen M. Buckley, Huidong Shi, Anand Jillella, Celalettin Ustun, Rekha Rao, Pravina Fernandez, Jianguang Chen, Ramesh Balusu, Sanjay Koul, Peter Atadja, Victor E. Marquez, Kapil N. Bhalla

Blood (2009) 114 (13): 2733–2743.

https://doi.org/10.1182/blood-2009-03-213496

Published: 2009

Includes: Supplemental data

Journal Articles

A Sensitive Molecular Method for Detection of Disseminating Hematopoietic Tumor Cells by Using Specific Epigenetic DNA Methylation Biomarkers

Michael X Wang, MD, PhD, Xiaohui Zhao, MD, PhD, Srilatha Nalluri, MS, Huan-You Wang, MD, PhD, Kristen H. Taylor, PhD, Huidong Shi, PhD, Charles W. Caldwell, MD, PhD

Blood (2008) 112 (11): 4850.

https://doi.org/10.1182/blood.V112.11.4850.4850

Published: 2008

Journal Articles

Detection of Minimal Residual Disease in Precursor B Lymphoblastic Leukemia (B-ALL) Patients by a Novel Epigenetic DNA Methylation Biomarker.

Michael X. Wang, MD, PhD, Deiter Duff, Huidong Shi, PhD, Kristen H. Taylor, PhD, Barbara A. Gruner, MD, Charles W. Caldwell, MD, PhD

Blood (2005) 106 (11): 4524.

https://doi.org/10.1182/blood.V106.11.4524.4524

Published: 2005

NARROW

Nrf2 sensitizes ferroptosis through l-2-hydroxyglutarate–mediated chromatin modifications in sickle cell disease

Incremental Clinically Relevant Information in 70 CLL Cases with Optical Genome Mapping: Going Beyond Karyotype and FISH

Transcriptome Sequencing Reveals Alternative Splicing Patterns and an Increased Sensitivity to Spliceosome Inhibition Associated MYD88 L265P Mutation in Chronic Lymphocytic Leukemia

Indoximod Combined with Standard Induction Chemotherapy Is Well Tolerated and Induces a High Rate of Complete Remission with MRD-Negativity in Patients with Newly Diagnosed AML: Results from a Phase 1 Trial

SF3B1 Mutation Causes Aberrant Splicing and Downregulation of PPP2R5A in Chronic Lymphocytic Leukemia

CDK7 Inhibitor THZ1 Inhibits Glycolytic Metabolism By Suppressing HIF1α Activity in Chronic Lymphocytic Leukemia

DNA Hypomethylation within B-Cell Enhancers and Super Enhancers Reveal a Dependency on Immune and Metabolic Mechanisms in Chronic Lymphocytic Leukemia

Heat Shock Factor 1 Promotes NF-Kb and B-Cell Signaling in a Preclinical Model of Chronic Lymphocytic Leukemia

Genome-Wide DNA Methylation Analysis Identifies Aberrant Epigenetic Changes in CD8+ T Cells from Chronic Lymphocytic Leukemia Patients

DNA Hypomethylation Leads to Aberrant Expression of PD-1 in Chronic Lymphocytic Leukemia

Genome-Wide DNA Methylation Landscape Defines IGHV Mutated and Unmutated B Cell Chronic Lymphocytic Leukemias

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

A Sensitive Molecular Method for Detection of Disseminating Hematopoietic Tumor Cells by Using Specific Epigenetic DNA Methylation Biomarkers

Detection of Minimal Residual Disease in Precursor B Lymphoblastic Leukemia (B-ALL) Patients by a Novel Epigenetic DNA Methylation Biomarker.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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