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Journal Articles

Efficacy of Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) and High Disease Activity with or without History of Aplastic Anemia in the International PNH Registry

Jong-Wook Lee, MD, Regis Peffault De Latour, MD PhD, Robert A. Brodsky, MD, Jun Ho Jang, MD PhD, Anita Hill, MBChB (Hons), PhD, Alexander Roeth, MD, Hubert Schrezenmeier, MD, Amanda Wilson, MPH, PhD, Jing L. Marantz, MD PhD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 3487.

https://doi.org/10.1182/blood.V130.Suppl_1.3487.3487

Published: 2017

Journal Articles

Analysis of Baseline Clinical Characteristics and Disease Burden in Patients Enrolled in the International Paroxysmal Nocturnal Hemoglobinuria Registry

Hubert Schrezenmeier, MD, Jaroslaw P. Maciejewski, PhD MD FACP, Alexander Roeth, MD, David J. Araten, MD, Yuzuru Kanakura, MD PhD, Loree Larratt, MD FRCP(C), Jamile M. Shammo, MD FASCP, FACP, Amanda Wilson, MPH, PhD, Gilda Shayan, Peter Hillmen, MBChB, PhD

Blood (2017) 130 (Supplement 1): 3488.

https://doi.org/10.1182/blood.V130.Suppl_1.3488.3488

Published: 2017

Journal Articles

Survival Among Acute Lymphocytic Leukemia Patients Conditional on Years Already Survived and Relative to the General Population in the United States

Raffi Tchekmedyian, BS, Aziz Nazha, MD, Anjali S. Advani, MD, Aaron T. Gerds, MDMS, Hetty E. Carraway, MD MBA, Matt Kalaycio, MD, Jaroslaw P. Maciejewski, PhD MD FACP, Navneet S. Majhail, MD MS, Mikkael A. Sekeres, MD MS, Sudipto Mukherjee, MD PhD MPH

Blood (2017) 130 (Supplement 1): 347.

https://doi.org/10.1182/blood.V130.Suppl_1.347.347

Published: 2017

Journal Articles

Survival Among Acute Myeloid Leukemia Patients Conditional on Years Already Survived and Relative to the General Population in the United States

Blood (2017) 130 (Supplement 1): 344.

https://doi.org/10.1182/blood.V130.Suppl_1.344.344

Published: 2017

Journal Articles

Mutational Burden before and after Allogeneic Hematopoietic Cell Transplantation (HCT) in Patients with Acute Myeloid Leukemia (AML)

Aziz Nazha, MD, Betty K. Hamilton, MD, Mikkael A. Sekeres, MD MS, Sudipto Mukherjee, MD PhD MPH, Aaron T. Gerds, MDMS, Rabi Hanna, MD, Cassandra M. Hirsch, BS, Teodora Kuzmanovic, BA, Karam Al-Issa, MD, Bartlomiej P. Przychodzen, MSc, Ronald Sobecks, MD, Matt Kalaycio, MD, Navneet S. Majhail, MD MS, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 3272.

https://doi.org/10.1182/blood.V130.Suppl_1.3272.3272

Published: 2017

Journal Articles

IDH1/2 -Mutated Acute Myeloid Leukemia Has Impaired DNA Damage Response and Is Sensitive to Monotherapy with the PARP Inhibitior Olaparib

Remco J Molenaar, Tomas Radivoyevitch, PhD, Yasunobu Nagata, MD PhD, Bartlomiej P. Przychodzen, MSc, Hideki Makishima, MD PhD, Hetty E. Carraway, MD MBA, Sudipto Mukherjee, MD PhD MPH, Mikkael A. Sekeres, MD MS, Cornelis van Noorden, PhD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 568.

https://doi.org/10.1182/blood.V130.Suppl_1.568.568

Published: 2017

Journal Articles

Acquired Somatic Mutations in T Cells in Patients with Aplastic Anemia and Hypoplastic Myelodysplastic Syndromes

Sofie Lundgren, Mikko Keränen, MD PhD, Kari Nousiainen, Samuli Eldfors, Sari Hannula, Tiina Hannunen, Pekka Ellonen, Gunilla Walldin, Michael Clemente, Freja Ebeling, MD PhD, Hanna Rajala, MD PhD, Jaroslaw P. Maciejewski, PhD MD FACP, Harri Lähdesmäki, PhD, Eva Hellstrom-Lindberg, MD PhD, Satu Mustjoki, MDPhD

Blood (2017) 130 (Supplement 1): 1169.

https://doi.org/10.1182/blood.V130.Suppl_1.1169.1169

Published: 2017

Journal Articles

High Frequency of Subclonal Myeloid Mutations Can be Found in Large Granular Lymphocyte Leukemia

Elise LeMelle, Cassandra M. Hirsch, BS, Michael Clemente, MS, Srinivasa Reddy Sanikommu, MD, Vera Adema, PhD, Hassan Awada, MD, Bartlomiej P. Przychodzen, MSc, Hetty E. Carraway, MD MBA, Alan Lichtin, MD, Mikkael A. Sekeres, MD MS, Sudipto Mukherjee, MD PhD MPH, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 1171.

https://doi.org/10.1182/blood.V130.Suppl_1.1171.1171

Published: 2017

Journal Articles

Paroxysmal Nocturnal Hemoglobinuria Results from Initial Clonal PIG-a Mosaicism

Michael J. Clemente, Bartlomiej Przychodzen, Cassandra M. Hirsch, BS, Bhumika J. Patel, MD, Taha Bat, Yasunobu Nagata, MD PhD, Marcin W. Wlodarski, MD PhD, Hideki Makishima, MD PhD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 1179.

https://doi.org/10.1182/blood.V130.Suppl_1.1179.1179

Published: 2017

Journal Articles

Non-Random Interactions between Founder and Subclonal Mutations Shape the Clinical and Morphological Features of MDS

Blood (2017) 130 (Supplement 1): 583.

https://doi.org/10.1182/blood.V130.Suppl_1.583.583

Published: 2017

Journal Articles

Somatic PRPF8 Mutations in Myeloid Neoplasia

Vera Adema, PhD, Cassandra M. Hirsch, BS, Bartlomiej P. Przychodzen, MSc, Yasunobu Nagata, MD PhD, Elise Lemelle, BS, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, PhD MD FACP, Richard A Padgett

Blood (2017) 130 (Supplement 1): 584.

https://doi.org/10.1182/blood.V130.Suppl_1.584.584

Published: 2017

Journal Articles

A Personalized Prediction Model to Risk Stratify Patients with Myelodysplastic Syndromes (MDS)

Aziz Nazha, MD, Rami S. Komrokji, MD, John Barnard, PhD, Karam Al-Issa, MD, Eric Padron, MD, Yazan F. Madanat, MD, Teodora Kuzmanovic, BA, Nour Abuhadra, MD, David P. Steensma, MD, Amy E. DeZern, MD, Gail J. Roboz, MD, Guillermo Garcia-Manero, MD, Alan F. List, MD, Jaroslaw P. Maciejewski, PhD MD FACP, Mikkael A. Sekeres, MD MS

Blood (2017) 130 (Supplement 1): 160.

https://doi.org/10.1182/blood.V130.Suppl_1.160.160

Published: 2017

Journal Articles

Novel Therapeutic Targets for DNMT3A Mutant Myeloid Neoplasms

Vera Adema, PhD, Suresh K. Balasubramanian, MD, Cassandra M. Hirsch, BS, Bartlomiej P. Przychodzen, MSc, James G Phillips, PhD, Daniel Lindner, MD PhD, Tomas Radivoyevitch, PhD, Sudipto Mukherjee, MD PhD MPH, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Francesc Sole, PhD, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 106.

https://doi.org/10.1182/blood.V130.Suppl_1.106.106

Published: 2017

Journal Articles

A Personalized Prediction Model to Risk Stratify Patients with Acute Myeloid Leukemia (AML)

Aziz Nazha, MD, Sudipto Mukherjee, MD PhD MPH, Karam Al-Issa, MD, Ahed Makhoul, MD, Vera Adema, PhD, Cassandra M. Hirsch, BS, Anjali S. Advani, MD, Aaron T. Gerds, MDMS, Matt Kalaycio, MD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, PhD MD FACP, Mikkael A. Sekeres, MD MS

Blood (2017) 130 (Supplement 1): 1408.

https://doi.org/10.1182/blood.V130.Suppl_1.1408.1408

Published: 2017

Journal Articles

Patterns of Genomic Associations Can Define Acute Myeloid Leukemia (AML) Phenotype

Aziz Nazha, MD, Mikkael A. Sekeres, MD MS, Karam Al-Issa, MD, Ahed Makhoul, MD, Vera Adema, PhD, Cassandra M. Hirsch, BS, Anjali S. Advani, MD, Bartlomiej P. Przychodzen, MSc, Teodora Kuzmanovic, BA, Babal K Jha, PhD, Aaron T. Gerds, MDMS, Hetty E. Carraway, MD MBA, Sudipto Mukherjee, MD PhD MPH, Matt Kalaycio, MD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 1409.

https://doi.org/10.1182/blood.V130.Suppl_1.1409.1409

Published: 2017

Journal Articles

BCOR Mutations in Myelodysplastic Syndromes (MDS): Mutation Characteristics Impact Clinical Outcomes

Nour Abuhadra, MD, Karam Al-Issa, MD, Sudipto Mukherjee, MD PhD MPH, Cassandra M. Hirsch, BS, Aaron T. Gerds, MDMS, Babal K Jha, PhD, Vera Adema, PhD, Hassan Awada, MD, Mohammad Fahad B Asad, MD MBBS, Abhinav Goyal, MD, Anjali S. Advani, MD, Yasunobu Nagata, MD PhD, Bartlomiej P. Przychodzen, MSc, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, PhD MD FACP, Mikkael A. Sekeres, MD MS, Aziz Nazha, MD

Blood (2017) 130 (Supplement 1): 5304.

https://doi.org/10.1182/blood.V130.Suppl_1.5304.5304

Published: 2017

Journal Articles

Modulation of TET2 Activity with Ascorbic Acid in Myeloid Neoplasia: Diagnostic and Therapeutic Implications

Edward F Greenberg, MD, Cassandra M. Hirsch, BS, Shi Chen, Xiaochen Liiu, Babal K Jha, PhD, Valeria Visconte, PhD, Dewen You, PhD, Bartlomiej P. Przychodzen, MSc, Thomas Laframboise, PhD, Hideki Makishima, MD PhD, Aziz Nazha, MD, Mingjiang Xu, MDPhD, Daniel Gackowski, PhD, Mridul Mukherji, D.Phil., Mikkael A. Sekeres, MD MS, Ryszard Ólinski, Professor, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 1205.

https://doi.org/10.1182/blood.V130.Suppl_1.1205.1205

Published: 2017

Journal Articles

Extent and Clinical Implications of Subclonal Diversity in Paroxysmal Nocturnal Hemoglobinuria

Mohammad Fahad B Asad, MD MBBS, Abhinav Goyal, MD, Hassan Awada, MD, Mai Aly, Cassandra Hirsch, Michael J. Clemente, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Sudipto Mukherjee, MD PhD MPH, Yasunobu Nagata, MD PhD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 779.

https://doi.org/10.1182/blood.V130.Suppl_1.779.779

Published: 2017

Journal Articles

Clinical and Molecular Characteristics of Therapy-Related Acute Lymphoblastic Leukemia

Blood (2017) 130 (Supplement 1): 3993.

https://doi.org/10.1182/blood.V130.Suppl_1.3993.3993

Published: 2017

Journal Articles

Clonal Architecture of TET2 Mutations Influences the Clinical Phenotype of Patients with Myeloid Neoplasms

Cassandra M. Hirsch, BS, Aziz Nazha, MD, Kneen Kassy, Manja Meggendorfer, PhD, Bartlomiej P. Przychodzen, MSc, Niroshan Nadarajah, Vera Adema, PhD, Yasunobu Nagata, MD PhD, Valeria Visconte, PhD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Ryszard Ólinski, Professor, Sudipto Mukherjee, MD PhD MPH, Babal K Jha, PhD, Thomas Laframboise, PhD, Tomas Radivoyevitch, PhD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 4228.

https://doi.org/10.1182/blood.V130.Suppl_1.4228.4228

Published: 2017

NARROW

Efficacy of Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) and High Disease Activity with or without History of Aplastic Anemia in the International PNH Registry

Analysis of Baseline Clinical Characteristics and Disease Burden in Patients Enrolled in the International Paroxysmal Nocturnal Hemoglobinuria Registry

Survival Among Acute Lymphocytic Leukemia Patients Conditional on Years Already Survived and Relative to the General Population in the United States

Survival Among Acute Myeloid Leukemia Patients Conditional on Years Already Survived and Relative to the General Population in the United States

Mutational Burden before and after Allogeneic Hematopoietic Cell Transplantation (HCT) in Patients with Acute Myeloid Leukemia (AML)

IDH1/2 -Mutated Acute Myeloid Leukemia Has Impaired DNA Damage Response and Is Sensitive to Monotherapy with the PARP Inhibitior Olaparib

Acquired Somatic Mutations in T Cells in Patients with Aplastic Anemia and Hypoplastic Myelodysplastic Syndromes

High Frequency of Subclonal Myeloid Mutations Can be Found in Large Granular Lymphocyte Leukemia

Paroxysmal Nocturnal Hemoglobinuria Results from Initial Clonal PIG-a Mosaicism

Non-Random Interactions between Founder and Subclonal Mutations Shape the Clinical and Morphological Features of MDS

Somatic PRPF8 Mutations in Myeloid Neoplasia

A Personalized Prediction Model to Risk Stratify Patients with Myelodysplastic Syndromes (MDS)

Novel Therapeutic Targets for DNMT3A Mutant Myeloid Neoplasms

A Personalized Prediction Model to Risk Stratify Patients with Acute Myeloid Leukemia (AML)

Patterns of Genomic Associations Can Define Acute Myeloid Leukemia (AML) Phenotype

BCOR Mutations in Myelodysplastic Syndromes (MDS): Mutation Characteristics Impact Clinical Outcomes

Modulation of TET2 Activity with Ascorbic Acid in Myeloid Neoplasia: Diagnostic and Therapeutic Implications

Extent and Clinical Implications of Subclonal Diversity in Paroxysmal Nocturnal Hemoglobinuria

Clinical and Molecular Characteristics of Therapy-Related Acute Lymphoblastic Leukemia

Clonal Architecture of TET2 Mutations Influences the Clinical Phenotype of Patients with Myeloid Neoplasms

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American Society of Hematology

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