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Jason N Berman
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Journal Articles

Characterizing the Role of KMT2C Mutations in Rapid-Onset Infant Leukemia

Keon Collett, Sarada Ketharnathan, Sergey V Prykhozhij, Benno C Orr, Jason N Berman
Journal: Blood
Blood (2022) 140 (Supplement 1): 5873.
https://doi.org/10.1182/blood-2022-165756
Published: 2022
Journal Articles

A Zebrafish Model of Dnajc21 Deficiency Identifies Essential Roles in Granulocyte Differentiation and Metabolic Regulation

Sarada Ketharnathan, Sergey V Prykhozhij, Anna Cordeiro, Yigal Dror, Jason N Berman
Journal: Blood
Blood (2022) 140 (Supplement 1): 5818.
https://doi.org/10.1182/blood-2022-169865
Published: 2022
Journal Articles

High-dose AraC is essential for the treatment of ML-DS independent of postinduction MRD: results of the COG AAML1531 trial

Clinical Trials & Observations
Johann Hitzler, Todd Alonzo, Robert Gerbing, Amy Beckman, Betsy Hirsch, Susana Raimondi, Karen Chisholm, Shelton Viola, Lisa Brodersen, Michael Loken, Spencer Tong, Todd Druley, Maureen O’Brien, Nobuko Hijiya, Amy Heerema-McKenney, Yi-Chang Wang, Reuven Shore, Jeffrey Taub, Alan Gamis, E. Anders Kolb, Jason N. Berman
Journal: Blood
Blood (2021) 138 (23): 2337–2346.
https://doi.org/10.1182/blood.2021012206
Published: 2021
Includes: Supplemental data
Journal Articles

Zebrafish Models Provide Novel Insights into the Disease Biology of Parn-Mutant Dyskeratosis Congenita and DNAJC21-Mutant Shwachman-Diamond Syndrome

Sarada Ketharnathan, Sergey Prykhozhij, Anna Cordeiro, Yigal Dror, Jason N Berman
Journal: Blood
Blood (2021) 138 (Supplement 1): 1110.
https://doi.org/10.1182/blood-2021-150481
Published: 2021
Journal Articles

Loss of iqgap1 (IQ Motif Containing GTPase Activating Protein 1) in Zebrafish Leads to Intracerebellar Hemorrhage, Morphological Abnormalities and Activates Hematopoietic Response

Sergey Prykhozhij, Lucia Caceres, Kevin Ban, Christopher McMaster, Johane M Robitaille, Jason N Berman
Journal: Blood
Blood (2021) 138 (Supplement 1): 2071.
https://doi.org/10.1182/blood-2021-148029
Published: 2021
Journal Articles

Improved outcomes for myeloid leukemia of Down syndrome: a report from the Children’s Oncology Group AAML0431 trial

Clinical Trials & Observations
Jeffrey W. Taub, Jason N. Berman, Johann K. Hitzler, April D. Sorrell, Norman J. Lacayo, Kelley Mast, David Head, Susana Raimondi, Betsy Hirsch, Yubin Ge, Robert B. Gerbing, Yi-Cheng Wang, Todd A. Alonzo, Dario Campana, Elaine Coustan-Smith, Prasad Mathew, Alan S. Gamis
Journal: Blood
Blood (2017) 129 (25): 3304–3313.
https://doi.org/10.1182/blood-2017-01-764324
Published: 2017
Includes: Supplemental data
Journal Articles

Down Syndrome AML Is Unique in Phenotype Both at Diagnosis and in Post Chemotherapy Regeneration

Elisabeth R Wilson, Lisa Eidenschink Brodersen, PhD, Barbara Katharina Zehentner, PhD, Andrew J. Menssen, Andrew P. Voigt, Laura Pardo, Denise A. Wells, MD, Johann Hitzler, MD FRCP (C), FAAP, Jason N. Berman, MD, Todd A. Alonzo, PhD, Samir B. Kahwash, Soheil Meshinchi, MD PhD, Michael R. Loken, PhD
Journal: Blood
Blood (2016) 128 (22): 1687.
https://doi.org/10.1182/blood.V128.22.1687.1687
Published: 2016
Journal Articles

The Novel Sulfonamidebenzamide ML291 Activates Apoptotic UPR Signaling in Pediatric Leukemia

Danielle Garshott, Nicole Melong, MSc, Tania T. Sarker, MD MPH, Yue Xi, PhD, Amy Brownell, Michael Callaghan, MD, Jason N. Berman, MD, Andrew Fribley, PhD
Journal: Blood
Blood (2016) 128 (22): 3523.
https://doi.org/10.1182/blood.V128.22.3523.3523
Published: 2016
Journal Articles

Phloridzin Docosahexaenoate (PZ-DHA) : A Novel Naturally Derived Drug Active in T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Niroshaathevi Arumuggam, BSc, Nicole Melong, MSc, Catherine K.L. Too, PhD, Jason N. Berman, MD, H.P. Vasantha Rupasinghe, PhD
Journal: Blood
Blood (2016) 128 (22): 5197.
https://doi.org/10.1182/blood.V128.22.5197.5197
Published: 2016
Journal Articles

Using the Zebrafish to Model the Tumour-Suppressor Effects of NUP98 in NUP98-NSD1 mediated AML

Corey Filiaggi, BScH, Vinothkumar Rajan, B.Tech, Sergey Prykhozhij, PhD, Adam P Deveau, BScH, MSc, Jason N. Berman, MD
Journal: Blood
Blood (2016) 128 (22): 5117.
https://doi.org/10.1182/blood.V128.22.5117.5117
Published: 2016
Journal Articles

The Zebrafish Provides Mechanistic Insights into the Role of Poly(A)-Specific Ribonuclease ( PARN ) in Hematopoietic Stem Cell (HSC) Homeostasis and Bone Marrow Failure

Adam P Deveau, BScH, MSc, Andrew J Coombs, BScH, Santhosh Dhanraj, BSc, MSc, Gretchen Wagner, BScH, Yigal Dror, MD FRCP(C), Jason N. Berman, MD
Journal: Blood
Blood (2015) 126 (23): 668.
https://doi.org/10.1182/blood.V126.23.668.668
Published: 2015
Journal Articles

A Humanized Zebrafish Transplant Model Expressing CXCL12 Provides an Enhanced In Vivo Therapeutic Screening Platform for T-ALL

Vinothkumar Rajan, B.Tech, Nicole Melong, M.Sc, Clinton JV Campbell, PhD MD, Graham Dellaire, PhD, Jason N. Berman, MD
Journal: Blood
Blood (2015) 126 (23): 4273.
https://doi.org/10.1182/blood.V126.23.4273.4273
Published: 2015
Journal Articles

Fishing with a Transgenic Line: Using Zebrafish to Elucidate Mechanisms and Therapeutics in NUP98-NSD1 AML

Corey Filiaggi, BScH, Adam P Deveau, BScH, MSc, Sergey Prykhozhij, PhD, Graham Dellaire, PhD, Jason N. Berman, MD
Journal: Blood
Blood (2015) 126 (23): 1638.
https://doi.org/10.1182/blood.V126.23.1638.1638
Published: 2015
Journal Articles

Bone Marrow Failure and Developmental Delay Caused By Mutations in Poly(A)-Specific Ribonuclease

Santhosh Dhanraj, MSc, Sethu Madhava Rao Gunja, MSc, Adam P Deveau, BScH, MSc, Mikael Nissbeck, MSc, Boonchai Boonyawat, MD, Andrew J Coombs, BScH, Alessandra Renieri, MD, Mafalda Mucciolo, MD, Annabella Marozza, MD, Sabrina Buoni, Lesley Turner, MD, Hongbing Li, PhD, Ameer Jarrar, MSc, Mathura Sabanayagam, BSc, Melanie Kirby, MD, Mary Shago, PhD, Dalila Pinto, PhD, Jason N. Berman, MD, Stephen W. Scherer, PhD FRSC, Anders Virtanen, PhD, Yigal Dror, MD FRCP(C)
Journal: Blood
Blood (2015) 126 (23): 2404.
https://doi.org/10.1182/blood.V126.23.2404.2404
Published: 2015
Journal Articles

Characterizing Transcriptional and Epigenetic Signatures Induced By FLT3-ITD Activation

Barbara Spitzer, MD, Olga A Guryanova, MD PhD, Omar Abdel-Wahab, MD, Nicole Kucine, MD, Mazhar Adli, PhD, Jason N. Berman, MD, Soheil Meshinchi, MD PhD, Bradley Bernstein, MD PhD, Raphael Pelossof, PhD, Christina Leslie, PhD, Ross L. Levine, MD
Journal: Blood
Blood (2014) 124 (21): 2186.
https://doi.org/10.1182/blood.V124.21.2186.2186
Published: 2014
Journal Articles

Preclinical Determination of the Efficacy of Epigenetic Therapy in High Risk Myeloid Disease Using the Zebrafish Model

Adam Deveau, BSc, MSc, Alexander Michael Forrester, BSc, PhD, Andrew J Coombs, BScH, Gretchen S Wagner, BScH, Clemens Grabher, PhD, Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, Matthew Mingay, BSc, Martin Hirst, PhD, A. Thomas Look, MD, Jason N. Berman, MD
Journal: Blood
Blood (2014) 124 (21): 436.
https://doi.org/10.1182/blood.V124.21.436.436
Published: 2014
Journal Articles

Improvement in Treatment Outcome and Identification of a New Prognostic Parameter in Down Syndrome Acute Myeloid Leukemia (DS-AML): Results of the Children’s Oncology Group (COG) Phase III AAML0431 Trial

Jeffrey W Taub, MD, Jason N Berman, MD, Johann K. Hitzler, MD, April D. Sorrell, MD, Norman J. Lacayo, MD, Kelley Mast, MD, David R. Head, MD, Susana C. Raimondi, PhD, Betsy A. Hirsch, PhD, Robert B. Gerbing, MA, Todd A. Alonzo, PhD, Dario Campana, MD PhD, Elaine Coustan-Smith, MS, Prasad Mathew, Alan S. Gamis, MD MPH
Journal: Blood
Blood (2014) 124 (21): 278.
https://doi.org/10.1182/blood.V124.21.278.278
Published: 2014
Journal Articles

Zebrafish Xenotransplantation and Focused Chemical Genomics: A Preclinical Therapeutic Model For T-Cell Acute Lymphoblastic Leukemia

Victoria L Bentley, BSc, Chansey J Veinotte, MSc, Dale Corkery, BSc., Marissa A Leblanc, PhD, Karen Bedard, PhD, Andrew P Weng, MD, PhD, Graham Dellaire, PhD., Jason N Berman, MD
Journal: Blood
Blood (2013) 122 (21): 2670.
https://doi.org/10.1182/blood.V122.21.2670.2670
Published: 2013
Journal Articles

Glycine Supplementation – A Novel Therapeutic Strategy for Congenital Sideroblastic Anemia.

Jason N Berman, MD, Pedro Fernandez-Murray, PhD, Gheyath Nasrallah, PhD, Noelia Dufay, PhD, Conrad V Fernandez, FRCPC, BSc, MD, Ameer Jarrar, MSc, Andrew J Coombs, BSc(Hon), Christopher McMaster, PhD
Journal: Blood
Blood (2012) 120 (21): 2087.
https://doi.org/10.1182/blood.V120.21.2087.2087
Published: 2012
Journal Articles

Epigenetic Therapy Inhibits NUP98-HOXA9 -Mediated Myeloid Disease – Decitabine and Valproic Acid Work Synergistically to Rescue Normal Hematopoiesis in Transgenic Zebrafish.

Adam Deveau, BSc(Hons), A. Michael Forrester, PhD, Clemens Grabher, Andrew J Coombs, BSc(Hon), Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, A. Thomas Look, M.D., Jason N Berman, MD
Journal: Blood
Blood (2012) 120 (21): 2391.
https://doi.org/10.1182/blood.V120.21.2391.2391
Published: 2012