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Journal Articles

Enhancer Hijacking of BCL11B Defines a Subtype of Lineage Ambiguous Acute Leukemia

Blood (2020) 136 (Supplement_2): LBA-3.

https://doi.org/10.1182/blood-2020-143881

Published: 2020

Journal Articles

Comprehensive Genomic Profiling of Pediatric Therapy-Related Myeloid Neoplasms Identifies Mecom Dysregulation to be Associated with Poor Outcome

Jason R Schwartz, MD PhD, Jing Ma, PhD, Michael P Walsh, PhD, Xiaolong Chen, PhD, Tamara Lamprecht, BS, Jennifer Kamens, MD, Scott Newman, PhD, Jinghui Zhang, PhD, Tanja A. Gruber, MD PhD, Xiaotu Ma, Jeffery M. Klco, MD PhD

Blood (2019) 134 (Supplement_1): 1394.

https://doi.org/10.1182/blood-2019-128665

Published: 2019

Journal Articles

Venetoclax in Combination with High-Dose Chemotherapy Is Active and Well-Tolerated in Children with Relapsed or Refractory Acute Myeloid Leukemia

Seth E Karol, MD, Thomas Alexander, MDMPH, Amit Budraja, PhD, Stanley Pounds, PhD, Kristin E Canavera, PhD, Lei Wang, MS, Joshua Wolf, MBBS, PhD, Jeffery M. Klco, MD PhD, Ahmed Hamed Salem, PhD FCP, Tammy Palenski, PhD, Norman J. Lacayo, MD, Ching-Hon Pui, MD, Joseph T. Opferman, PhD, Jeffrey Rubnitz, MD PhD

Blood (2019) 134 (Supplement_1): 178.

https://doi.org/10.1182/blood-2019-127716

Published: 2019

Journal Articles

NUP98-KDM5A Fusion Induces Hematopoietic Cell Proliferation and Alters Myelo-Erythropoietic Differentiation

Jonathan Miller, MD PhD, Ryan Hiltenbrand, MS, Tamara Lamprecht, BS, Aman Seth, MS, Sherif Abdelhamed, PhD, Ilaria Iacobucci, PhD, Charles G. Mullighan, MBBS, MD, Jeffery M. Klco, MD PhD

Blood (2019) 134 (Supplement_1): 3775.

https://doi.org/10.1182/blood-2019-130768

Published: 2019

Journal Articles

Role of Genetic Evolution and Germline Mutations in SAMD9 and SAMD9L Genes

Jason R Schwartz, MD PhD, Marcin W. Wlodarski, MD PhD, Jeffery M. Klco, MD PhD

Blood (2019) 134 (Supplement_1): SCI-33.

https://doi.org/10.1182/blood-2019-121042

Published: 2019

Journal Articles

Integrative Analysis of Pediatric Acute Leukemia Identifies Immature Subtypes That Span a T Lineage and Myeloid Continuum with Distinct Prognoses

Blood (2019) 134 (Supplement_1): 918.

https://doi.org/10.1182/blood-2019-127411

Published: 2019

Journal Articles

The Mutational Profile of Pediatric Therapy-Related Myeloid Neoplasms

Jason R Schwartz, MD PhD, Michael P Walsh, PhD, Jing Ma, PhD, Tamara Lamprecht, B.S., Raul C Ribeiro, MD, Jeffery M. Klco, MD PhD

Blood (2018) 132 (Supplement 1): 2775.

https://doi.org/10.1182/blood-2018-99-118995

Published: 2018

Journal Articles

Novel V1551L Mutation in SAMD9L Inhibits Cell Cycle Progression and Results in Pancytopenia That Progresses to MDS with Monosomy 7

Rebecca Ortolano, MD, Dina S. Parekh, MD, Benjamin J Rosen, MD, Victoria Bryant, PhD MSc, Dong-Hui Chen, PhD, Jeffery M. Klco, MD PhD, Wendy Herlihy Raskind, MD PhD, Kenneth Lieuw, MD PhD

Blood (2018) 132 (Supplement 1): 3863.

https://doi.org/10.1182/blood-2018-99-120250

Published: 2018

Journal Articles

Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB

Anna L. Brown, PhD BSc, Mark Armstrong, MSc, David Lawrence, Paul Wang, Peer Arts, PhD, Nicolas Duployez, PharmD, PhD, Jane Churpek, MD, Kiran Tawana, MD, Erin Degelman, MSc, BSc, Georges Natsoulis, PhD, Monica L. Guzman, PhD, Mrinal M. Patnaik, MD MBBS, Akiko Shimamura, MD PhD, Alan B. Cantor, MD PhD, Tim Ripperger, MD PhD, Brigitte Schlegelberger, MD PhD, Doris Steinemann, PhD, Courtney D. DiNardo, MD MSc, Cristina Mecucci, MD PhD, Elvira DRP Velloso, MD PhD, Fabio PS Santos, MD, Marcela CA Silva, Uma Borate, MD, Shannon K. McWeeney, PhD, Grzegorz Nalepa, MD PhD, Susanne Ragg, MD PhD, Erika Mijin Kwon, PhD, Anupriya Agarwal, PhD, Stephen Langabeer, PhD, Jeffery M. Klco, MD PhD, Jun J. Yang, PhD, Cecily Forsyth, FRACP, FRCPA, MBBS, Sally Mapp, MD PhD, Helen Mar Fan, MD, Lesley Rawlings, PhD, Rachel Susman, Sue Morgan, FRACP, FRCPA, MBBS, Andrew H Wei, MBBS,PhD, Inderjeet Dokal, MD, Tom Vulliamy, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD, Deepak Singhal, MBBS, MD FRACP, FRCPA, Susan Branford, PhD, Elli Papaemmanuil, PhD, Jean Soulier, MDPhD, Stefan Fröhling, MD, Alwin Kramer, MD, Guy Sauvageau, MD PhD, Neil Morgan, Carolyn Owen, Csaba Bödör, PhD, Jude Fitzgibbon, Hugh Y. Rienhoff, Jr., MD, Mineo Kurokawa, MD PhD, Lucy Godley, MD PhD, Claude Preudhomme, Paul P Liu, MD PhD, Nicola Poplawski, MD, Christopher N. Hahn, PhD, Hamish S. Scott, PhD

Blood (2018) 132 (Supplement 1): 5241.

https://doi.org/10.1182/blood-2018-99-118017

Published: 2018

Journal Articles

Downregulation of MHC Class II in Relapsed AML Cells after Allogeneic Transplantation

Blood (2017) 130 (Supplement 1): 2678.

https://doi.org/10.1182/blood.V130.Suppl_1.2678.2678

Published: 2017

Journal Articles

The Genomic Landscape of Pediatric Myelodysplastic Syndromes

Jason R. Schwartz, MD PhD, Michael P. Walsh, PhD, Jing Ma, PhD, Tamara Lamprecht, B.S., Shuoguo Wang, PhD, Gang Wu, PhD, John Easton, PhD, Raul C. Ribeiro, MD, Jeffery M. Klco, MD PhD

Blood (2016) 128 (22): 956.

https://doi.org/10.1182/blood.V128.22.956.956

Published: 2016

Journal Articles

Comprehensive Analysis Of HOX Gene Expression and DNA Methylation From 189 Primary AMLs Demonstrates Canonical Patterns Associated With Hematopoietic Stem/Progenitors and Recurrent AML Mutations

David H Spencer, MD/PhD, Margaret A. Young, MD/PhD, Jeffery M. Klco, MD/PhD, Timothy J. Ley, MD

Blood (2013) 122 (21): 2496.

https://doi.org/10.1182/blood.V122.21.2496.2496

Published: 2013

Journal Articles

Functional Early Hematopoietic Progenitor Cells Derived From Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells

Cheng Li, Daniel R. George, Nichole M. Helton, Jeffery M. Klco, MD/PhD, Jacqueline L. Mudd, Timothy J. Ley, MD

Blood (2013) 122 (21): 2421.

https://doi.org/10.1182/blood.V122.21.2421.2421

Published: 2013

Journal Articles

DNMT3A R882H Overexpression Leads To Hematopoietic and Skin Alterations In Transgenic Mice

Angela M. Verdoni, PhD, Christopher B Cole, Jeffery M. Klco, MD/PhD, Timothy J. Ley, MD

Blood (2013) 122 (21): 479.

https://doi.org/10.1182/blood.V122.21.479.479

Published: 2013

Journal Articles

Subclonal “skewing” Of De Novo AML Samples After Engraftment In Immunodeficient Mice

Jeffery M. Klco, MD/PhD, David H Spencer, MD/PhD, Christopher A Miller, PhD, Tamara Lamprecht, Dan George, Robert S. Fulton, Richard K Wilson, PhD, Timothy J. Ley, MD

Blood (2013) 122 (21): 609.

https://doi.org/10.1182/blood.V122.21.609.609

Published: 2013

Journal Articles

Deep Digital Sequencing Identifies an AML Subclone with Enhanced in Vitro and in Vivo Growth Properties Associated with Disease Relapse

Jeffery M. Klco, MD/PhD, David H Spencer, MD/PhD, Chris Miller, PhD, Tamara Lamprecht, Robert S. Fulton, John S. Welch, MD/PhD, Li Ding, Richard K Wilson, Timothy J. Ley, MD

Blood (2012) 120 (21): 407.

https://doi.org/10.1182/blood.V120.21.407.407

Published: 2012

Journal Articles

Functional Hematopoietic Cells Derived From Mouse Embryonic Stem Cells.

Cheng Li, Daniel R. George, Nichole M. Havey, Jeffery M. Klco, MD/PhD, Timothy J. Ley, MD

Blood (2012) 120 (21): 2304.

https://doi.org/10.1182/blood.V120.21.2304.2304

Published: 2012

Journal Articles

Next-Generation Sequencing: A Discovery Tool for Blood Disorders

Elaine R. Mardis, PhD, Li Ding, PhD, Peter Westervelt, John S. Welch, Jeffery M. Klco, MD, John F. DiPersio, MD, PhD, Richard K Wilson, Timothy J. Ley, MD

Blood (2012) 120 (21): SCI-10.

https://doi.org/10.1182/blood.V120.21.SCI-10.SCI-10

Published: 2012

Journal Articles

In Vitro Decitabine Treatment Demonstrates Heterogeneous Changes in Methylation and Gene Expression in Primary AML Samples.

David H Spencer, MD/PhD, Jeffery M. Klco, MD/PhD, Tamara Lamprecht, Todd Wylie, BS, Vincent Magrini, PhD, Jasreet Hundal, MS, Jason Walker, BA, BS, Nobish Varghese, MS, Matthew R Meyer, PhD, Petra Gilmore, PhD, Reid Townsend, MD, PhD, Elaine R. Mardis, PhD, Timothy J. Ley, MD

Blood (2012) 120 (21): 2527.

https://doi.org/10.1182/blood.V120.21.2527.2527

Published: 2012

Journal Articles

Activation of Notch Signaling Is An Early Event in the Development of PML-Rara -Induced Acute Promyelocytic Leukemia (APL)

Nicole R. Grieselhuber, Jeffery M. Klco, MD, Angela M. Verdoni, Timothy J Ley, MD

Blood (2011) 118 (21): 2468.

https://doi.org/10.1182/blood.V118.21.2468.2468

Published: 2011

NARROW

Enhancer Hijacking of BCL11B Defines a Subtype of Lineage Ambiguous Acute Leukemia

Comprehensive Genomic Profiling of Pediatric Therapy-Related Myeloid Neoplasms Identifies Mecom Dysregulation to be Associated with Poor Outcome

Venetoclax in Combination with High-Dose Chemotherapy Is Active and Well-Tolerated in Children with Relapsed or Refractory Acute Myeloid Leukemia

NUP98-KDM5A Fusion Induces Hematopoietic Cell Proliferation and Alters Myelo-Erythropoietic Differentiation

Role of Genetic Evolution and Germline Mutations in SAMD9 and SAMD9L Genes

Integrative Analysis of Pediatric Acute Leukemia Identifies Immature Subtypes That Span a T Lineage and Myeloid Continuum with Distinct Prognoses

The Mutational Profile of Pediatric Therapy-Related Myeloid Neoplasms

Novel V1551L Mutation in SAMD9L Inhibits Cell Cycle Progression and Results in Pancytopenia That Progresses to MDS with Monosomy 7

Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB

Downregulation of MHC Class II in Relapsed AML Cells after Allogeneic Transplantation

The Genomic Landscape of Pediatric Myelodysplastic Syndromes

Comprehensive Analysis Of HOX Gene Expression and DNA Methylation From 189 Primary AMLs Demonstrates Canonical Patterns Associated With Hematopoietic Stem/Progenitors and Recurrent AML Mutations

Functional Early Hematopoietic Progenitor Cells Derived From Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells

DNMT3A R882H Overexpression Leads To Hematopoietic and Skin Alterations In Transgenic Mice

Subclonal “skewing” Of De Novo AML Samples After Engraftment In Immunodeficient Mice

Deep Digital Sequencing Identifies an AML Subclone with Enhanced in Vitro and in Vivo Growth Properties Associated with Disease Relapse

Functional Hematopoietic Cells Derived From Mouse Embryonic Stem Cells.

Next-Generation Sequencing: A Discovery Tool for Blood Disorders

In Vitro Decitabine Treatment Demonstrates Heterogeneous Changes in Methylation and Gene Expression in Primary AML Samples.

Activation of Notch Signaling Is An Early Event in the Development of PML-Rara -Induced Acute Promyelocytic Leukemia (APL)

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American Society of Hematology

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ASH Publications

American Society of Hematology

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