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Journal Articles

Phase 1/2 Study of Donor-Derived Anti-CD33 Chimeric Antigen Receptor Expressing T Cells (VCAR33) in Patients with Relapsed or Refractory Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Transplantation

Nirali N. Shah, Jacques Azzi, Brenda W Cooper, Abhinav Deol, John DiPersio, Divya Koura, Brian McClune, Lori S. Muffly, Muhammad Umair Mushtaq, Rupa Narayan, Hyung Chan Suh, Gregory Yanik, Sritama Nath, Jennifer Whangbo, Guenther Koehne

Blood (2023) 142 (Supplement 1): 4862.

https://doi.org/10.1182/blood-2023-180990

Published: 2023

Journal Articles

Single Cell Resolution Mapping of Hematopoietic Stem and Progenitor Cell States throughout Human Life

Hojun Li, MD PhD, Vincent Butty, Guinevere Connelly, Vivian Morris, George Q. Daley, MD PhD, Jennifer Whangbo, MD PhD, Edroaldo Lummertz da rocha, PhD, Robert Grant Rowe, MDPhD

Blood (2020) 136 (Supplement 1): 31.

https://doi.org/10.1182/blood-2020-136380

Published: 2020

Journal Articles

Longitudinal Changes in the Intestinal Microbiome Composition Following Gut Decontamination in Pediatric Allogeneic Hematopoietic Stem Cell Transplant Patients: A Pilot Study

Christopher Severyn, MD PhD, Wendy B. London, PhD, Paige Kao, MPH, Sophie Silverstein, BS, Michelle Li, BS, Soomin Kim, BA, Kelly Verrill, BSN, Jerome Ritz, MD, Ami S. Bhatt, MD PhD, Jennifer Whangbo, MD PhD

Blood (2019) 134 (Supplement_1): 5665.

https://doi.org/10.1182/blood-2019-122480

Published: 2019

Journal Articles

Low-Dose Interleukin-2 Therapy Enhances Cytotoxicity of CD56 bright NK Cells in Patients with Chronic Gvhd

Tomohiro Kubo, MD PhD, Rizwan Romee, MD, John Koreth, MBBS, DPhil, Roger Belizaire, MD PhD, Yusuke Kamihara, MD PhD, Hongye Liu, PhD, Takeru Asano, MDPhD, Jennifer Whangbo, MD PhD, Masahiro Hirakawa, MD PhD, Sarah Nikiforow, MD PhD, Mahasweta Gooptu, MD, Vincent T. Ho, MD, Corey S. Cutler, MD MPH, Edwin P. Alyea, III, MD, Joseph H. Antin, MD, Robert J. Soiffer, MD, Jerome Ritz, MD PhD

Blood (2018) 132 (Supplement 1): 606.

https://doi.org/10.1182/blood-2018-99-109918

Published: 2018

Journal Articles

Individual Patient Dose-Escalated Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Vs.-Host Disease in Children and Adults: Safety, Efficacy and Immune Correlates

Blood (2017) 130 (Supplement 1): 3248.

https://doi.org/10.1182/blood.V130.Suppl_1.3248.3248

Published: 2017

Journal Articles

Low-Dose Interleukin-2 Therapy Activates Circulating T Follicular Regulatory Cells and Suppresses Circulating T Follicular Helper Cells in Patients with Chronic Gvhd

Yusuke Kamihara, MD PhD, Edouard Forcade, MD, John Koreth, MBBS, DPhil, Hongye Liu, PhD, Tomohiro Kubo, MD PhD, Jennifer Whangbo, MD PhD, Masahiro Hirakawa, MD PhD, Sarah Nikiforow, MD PhD, Vincent T Ho, MD, Philippe Armand, MD PhD, Corey S. Cutler, MD MPH, Edwin Alyea, III, MD, Bruce Blazar, MD, Joseph H. Antin, MD, Robert J. Soiffer, MD, Jerome Ritz, MD

Blood (2017) 130 (Supplement 1): 74.

https://doi.org/10.1182/blood.V130.Suppl_1.74.74

Published: 2017

Journal Articles

The Activated TGFβ Pathway in Shwachman Diamond Syndrome Impairs Hematopoiesis and Is Down-Regulated By Deletion of 7q

Melisa Ruiz-Gutierrez, MD PhD, Cailin Joyce, PhD, Ozge Vargel Bolukbasi, PhD, Andriana Kotini, PhD, Gabriela Alexe, Jennifer Whangbo, MD PhD, David Russell, MDPhD, Kimberly Stegmaier, MD, Carl D. Novina, MD PhD, Eirini P. Papapetrou, MD PhD, Akiko Shimamura, MD

Blood (2017) 130 (Supplement 1): 875.

https://doi.org/10.1182/blood.V130.Suppl_1.875.875

Published: 2017

Journal Articles

Extra-Corporeal Photopheresis Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Vs.-Host Disease: Efficacy, Safety and Immune Correlates

John Koreth, MBBS, DPhil, Haesook T Kim, PhD, Roger Belizaire, MD PhD, Samuel J Poryanda, BSc, Carol Reynolds, PhD, Jennifer Whangbo, MD PhD, Sarah Nikiforow, Edwin Alyea, III, MD, Philippe Armand, MD PhD, Corey Cutler, MD MPH, FRCPC, Vincent T Ho, MD, Bruce Blazar, MD, Joseph H. Antin, MD, Jerome Ritz, MD, Robert J. Soiffer, MD

Blood (2017) 130 (Supplement 1): 515.

https://doi.org/10.1182/blood.V130.Suppl_1.515.515

Published: 2017

Journal Articles

Phase I Trial of Regulatory T-Cell Donor Lymphocyte Infusion Plus Daily Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Versus-Host Disease

Blood (2017) 130 (Supplement 1): 511.

https://doi.org/10.1182/blood.V130.Suppl_1.511.511

Published: 2017

Journal Articles

Functional Effects of Low-Dose IL-2 in Patients with Chronic Graft Versus Host Disease

Jennifer Whangbo, MD PhD, Bryn Falahee, John Koreth, MD, Haesook T. Kim, PhD, Sarah Nikiforow, MD PhD, Vincent T. Ho, MD, Corey S. Cutler, MD MPH, Philippe Armand, MD PhD, Edwin P. Alyea, MD, Joseph H. Antin, MD, Robert J. Soiffer, MD, Jerome Ritz, MD

Blood (2016) 128 (22): 667.

https://doi.org/10.1182/blood.V128.22.667.667

Published: 2016

Journal Articles

Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease

John Koreth, Haesook T. Kim, Kyle T. Jones, Paulina B. Lange, Carol G. Reynolds, Marie J. Chammas, Katherine Dusenbury, Jennifer Whangbo, Sarah Nikiforow, Edwin P. Alyea, III, Philippe Armand, Corey S. Cutler, Vincent T. Ho, Yi-Bin Chen, David Avigan, Bruce R. Blazar, Joseph H. Antin, Jerome Ritz, Robert J. Soiffer

Blood (2016) 128 (1): 130–137.

https://doi.org/10.1182/blood-2016-02-702852

Published: 2016

Includes: Supplemental data

Journal Articles

Unbalanced recovery of regulatory and effector T cells after allogeneic stem cell transplantation contributes to chronic GVHD

Ana C. Alho, Haesook T. Kim, Marie J. Chammas, Carol G. Reynolds, Tiago R. Matos, Edouard Forcade, Jennifer Whangbo, Sarah Nikiforow, Corey S. Cutler, John Koreth, Vincent T. Ho, Philippe Armand, Joseph H. Antin, Edwin P. Alyea, Joao F. Lacerda, Robert J. Soiffer, Jerome Ritz

Blood (2016) 127 (5): 646–657.

https://doi.org/10.1182/blood-2015-10-672345

Published: 2016

Includes: Supplemental data

Journal Articles

IL-2, IL-7, IL-15 and IL-6 Induce Differential Activation of Naive and Memory T Cell Subsets

Masahiro Hirakawa, MD PhD, Tiago R Matos, MD MSc, Edouard Forcade, MD, Kathy S. Wang, PhD, Eduardo L Espada, MD, Jennifer Whangbo, MD PhD, Carol G Reynolds, PhD, Marie J Chammas, Kazuyuki Murase, MD PhD, Jerome Ritz, MD

Blood (2015) 126 (23): 3425.

https://doi.org/10.1182/blood.V126.23.3425.3425

Published: 2015

Journal Articles

Long-Term Homeostatic Effects of Daily Low-Dose IL-2 on CD4+ FoxP3+ Regulatory T Cells in Patients with Active Chronic Graft-Versus-Host Disease

Jennifer Whangbo, MD PhD, John Koreth, MBBS, DPhil, Haesook T. Kim, PhD, Katharine Dusenbury, Ana Cristina Alho, MD, Carol G Reynolds, PhD, Marie J Chammas, Kyle T Jones, Sarah Nikiforow, MD PhD, Corey S Cutler, MD MPH, Vincent T. Ho, MD, Philippe Armand, MD PhD, Edwin P. Alyea, MD, Robert J. Soiffer, MD, Joseph H. Antin, MD, Jerome Ritz, MD

Blood (2015) 126 (23): 3133.

https://doi.org/10.1182/blood.V126.23.3133.3133

Published: 2015

Journal Articles

IL-2 Induces Selective Activation of Helios-Positive Regulatory T Cells and CD56 bright NK Cells in Vitro and in Patients with Chronic Gvhd Receiving Low-Dose IL-2 Therapy

Masahiro Hirakawa, MD PhD, Tiago R Matos, MD MSc, John Koreth, MBBS, DPhil, Edouard Forcade, MD, Jennifer Whangbo, MD PhD, Kazuyuki Murase, MD PhD, Hongye Liu, Sarah Nikiforow, MD PhD, Vincent T Ho, MD, Corey S Cutler, MD MPH, Philippe Armand, MD PhD, Edwin P. Alyea, MD, Joseph H. Antin, MD, Robert J. Soiffer, MD, Jerome Ritz, MD

Blood (2015) 126 (23): 919.

https://doi.org/10.1182/blood.V126.23.919.919

Published: 2015

Journal Articles

Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Vs.-Host Disease: Phase 2 and Long Term Efficacy, Safety and Immune Correlates

John Koreth, MBBS, DPhil, Haesook T. Kim, PhD, Kyle T. Jones, BSc, Carol G Reynolds, PhD, Marie J Chammas, BSc, Katherine Dusenbury, BSc, Jennifer Whangbo, MD PhD, Sarah Nikiforow, MD PhD, Edwin P. Alyea, MD, Philippe Armand, MD PhD, Corey S Cutler, MD MPH, Vincent T Ho, MD, Yi-Bin Chen, MD, David Avigan, MD, Joseph H Antin, MD, Jerome Ritz, MD, Robert J Soiffer, MD

Blood (2014) 124 (21): 41.

https://doi.org/10.1182/blood.V124.21.41.41

Published: 2014

Journal Articles

Binding Of Immune Serine Proteases To Nucleic Acids Enhances Their Nuclear Localization and Promotes Their Cleavage Of Nucleic Acid-Binding Protein Substrates

Jennifer Whangbo, MD, PhD, Marshall Thomas, Geoffrey McCrossan, Aaron Deutsch, Kimberly Martinod, Michael Walch, MD, Judy Lieberman, MD, PhD

Blood (2013) 122 (21): 3471.

https://doi.org/10.1182/blood.V122.21.3471.3471

Published: 2013

NARROW

Phase 1/2 Study of Donor-Derived Anti-CD33 Chimeric Antigen Receptor Expressing T Cells (VCAR33) in Patients with Relapsed or Refractory Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Transplantation

Single Cell Resolution Mapping of Hematopoietic Stem and Progenitor Cell States throughout Human Life

Longitudinal Changes in the Intestinal Microbiome Composition Following Gut Decontamination in Pediatric Allogeneic Hematopoietic Stem Cell Transplant Patients: A Pilot Study

Low-Dose Interleukin-2 Therapy Enhances Cytotoxicity of CD56 bright NK Cells in Patients with Chronic Gvhd

Individual Patient Dose-Escalated Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Vs.-Host Disease in Children and Adults: Safety, Efficacy and Immune Correlates

Low-Dose Interleukin-2 Therapy Activates Circulating T Follicular Regulatory Cells and Suppresses Circulating T Follicular Helper Cells in Patients with Chronic Gvhd

The Activated TGFβ Pathway in Shwachman Diamond Syndrome Impairs Hematopoiesis and Is Down-Regulated By Deletion of 7q

Extra-Corporeal Photopheresis Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Vs.-Host Disease: Efficacy, Safety and Immune Correlates

Phase I Trial of Regulatory T-Cell Donor Lymphocyte Infusion Plus Daily Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Versus-Host Disease

Functional Effects of Low-Dose IL-2 in Patients with Chronic Graft Versus Host Disease

Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease

Unbalanced recovery of regulatory and effector T cells after allogeneic stem cell transplantation contributes to chronic GVHD

IL-2, IL-7, IL-15 and IL-6 Induce Differential Activation of Naive and Memory T Cell Subsets

Long-Term Homeostatic Effects of Daily Low-Dose IL-2 on CD4+ FoxP3+ Regulatory T Cells in Patients with Active Chronic Graft-Versus-Host Disease

IL-2 Induces Selective Activation of Helios-Positive Regulatory T Cells and CD56 bright NK Cells in Vitro and in Patients with Chronic Gvhd Receiving Low-Dose IL-2 Therapy

Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Vs.-Host Disease: Phase 2 and Long Term Efficacy, Safety and Immune Correlates

Binding Of Immune Serine Proteases To Nucleic Acids Enhances Their Nuclear Localization and Promotes Their Cleavage Of Nucleic Acid-Binding Protein Substrates

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American Society of Hematology

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American Society of Hematology

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