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Journal Articles

Structural and Functional Characterization of a Codon Optimized Coagulation Factor VIII

Svetlana A Shestopal, PhD, James H Kurasawa, MS, Jian-Jiang Hao, PhD, Elena Karnaukhova, PhD, Yideng Liang, PhD, Min Lin, PhD, Mikhail V Ovanesov, PhD, Timothy K Lee, PhD, John H McVey, PhD, Andrey G Sarafanov, PhD

Blood (2016) 128 (22): 3765.

https://doi.org/10.1182/blood.V128.22.3765.3765

Published: 2016

Journal Articles

Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant

Blood (2013) 121 (17): 3335–3344.

https://doi.org/10.1182/blood-2012-10-462200

Published: 2013

Includes: Supplemental data

Journal Articles

AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage

Christopher Binny, Jenny McIntosh, Marco Della Peruta, Hanna Kymalainen, Edward G. D. Tuddenham, Suzanne M. K. Buckley, Simon N. Waddington, John H. McVey, Yunyu Spence, Christopher L. Morton, Adrian J. Thrasher, John T. Gray, Francis J. Castellino, Alice F. Tarantal, Andrew M. Davidoff, Amit C. Nathwani

Blood (2012) 119 (4): 957–966.

https://doi.org/10.1182/blood-2011-09-377630

Published: 2012

Includes: Supplemental data

Journal Articles

Codon optimization of human factor VIII cDNAs leads to high-level expression

Natalie J. Ward, Suzanne M. K. Buckley, Simon N. Waddington, Thierry VandenDriessche, Marinee K. L. Chuah, Amit C. Nathwani, Jenny McIntosh, Edward G. D. Tuddenham, Christine Kinnon, Adrian J. Thrasher, John H. McVey

Blood (2011) 117 (3): 798–807.

https://doi.org/10.1182/blood-2010-05-282707

Published: 2011

Includes: Supplemental data

Journal Articles

Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors

Raul Alba, Angela C. Bradshaw, Lynda Coughlan, Laura Denby, Robert A. McDonald, Simon N. Waddington, Suzanne M. K. Buckley, Jenny A. Greig, Alan L. Parker, Ashley M. Miller, Hongjie Wang, Andre Lieber, Nico van Rooijen, John H. McVey, Stuart A. Nicklin, Andrew H. Baker

Blood (2010) 116 (15): 2656–2664.

https://doi.org/10.1182/blood-2009-12-260026

Published: 2010

Includes: Supplemental data

Journal Articles

O tissue factor, where art thou?

John H. McVey

Blood (2010) 116 (5): 676–677.

https://doi.org/10.1182/blood-2010-05-283135

Published: 2010

Journal Articles

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

Raul Alba, Angela C. Bradshaw, Alan L. Parker, David Bhella, Simon N. Waddington, Stuart A. Nicklin, Nico van Rooijen, Jerome Custers, Jaap Goudsmit, Dan H. Barouch, John H. McVey, Andrew H. Baker

Blood (2009) 114 (5): 965–971.

https://doi.org/10.1182/blood-2009-03-208835

Published: 2009

Includes: Supplemental data

Journal Articles

FVIIa gene delivery: potential treatment for hemophilia?

John H. McVey

Blood (2009) 113 (16): 3649–3650.

https://doi.org/10.1182/blood-2009-02-201723

Published: 2009

Journal Articles

Tissue Specific Expression of Alternatively Spliced Forms of Tissue Factor Pathway Inhibitor (TFPI) in Mice

Susan A. Maroney, Josephine P. Ferrel, Shuchong Pan, Thomas A. White, Robert D. Simari, John H McVey, Alan E Mast

Blood (2008) 112 (11): 1026.

https://doi.org/10.1182/blood.V112.11.1026.1026

Published: 2008

Journal Articles

Regenerative repair after endoluminal injury in mice with specific antagonism of protease activated receptors on CD34 + vascular progenitors

Daxin Chen, Joel M. Abrahams, Leanne M. Smith, John H. McVey, Robert I. Lechler, Anthony Dorling

Blood (2008) 111 (8): 4155–4164.

https://doi.org/10.1182/blood-2007-10-120295

Published: 2008

Journal Articles

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

Alan L. Parker, Simon N. Waddington, Campbell G. Nicol, Dmitry M. Shayakhmetov, Suzanne M. Buckley, Laura Denby, Geoffrey Kemball-Cook, Shaoheng Ni, Andre Lieber, John H. McVey, Stuart A. Nicklin, Andrew H. Baker

Blood (2006) 108 (8): 2554–2561.

https://doi.org/10.1182/blood-2006-04-008532

Published: 2006

Journal Articles

The Secretion Efficiency of Factor VIII Can Be Regulated by the Size and Oligosaccharide Content of the B Domain.

Steven W. Pipe, MD, Hongzhi Z. Miao, Philip F. Kucab, John H. McVey, PhD, Randal J. Kaufman, PhD

Blood (2005) 106 (11): 687.

https://doi.org/10.1182/blood.V106.11.687.687

Published: 2005

Journal Articles

A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome

Christiane Albrecht, John H. McVey, James I. Elliott, Alessandro Sardini, Ildiko Kasza, Andrew D. Mumford, Rossi P. Naoumova, Edward G. D. Tuddenham, Katalin Szabo, Christopher F. Higgins

Blood (2005) 106 (2): 542–549.

https://doi.org/10.1182/blood-2004-05-2056

Published: 2005

Journal Articles

Inhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium

Daxin Chen, Konstantinos Giannopoulos, Paul G. Shiels, Zoe Webster, John H. McVey, Geoff Kemball-Cook, Edward Tuddenham, Marilyn Moore, Robert Lechler, Anthony Dorling

Blood (2004) 104 (5): 1344–1349.

https://doi.org/10.1182/blood-2003-12-4365

Published: 2004

Journal Articles

Functional characterization of factor V-Ile359Thr: a novel mutation associated with thrombosis

Mårten Steen, Eva A. Norstrøm, Ann-Louise Tholander, Paula H. B. Bolton-Maggs, Andrew Mumford, John H. McVey, Edward G. D. Tuddenham, Björn Dahlbäck

Blood (2004) 103 (9): 3381–3387.

https://doi.org/10.1182/blood-2003-06-2092

Published: 2004

Journal Articles

Exclusion of the First EGF Domain of Factor VII by a Splice Site Mutation Causes Lethal Factor VII Deficiency

John H. McVey, Emma J. Boswell, Osamu Takamiya, Gabriel Tamagnini, Victor Valente, Teresa Fidalgo, Mark Layton, Edward G.D. Tuddenham

Blood (1998) 92 (3): 920–926.

https://doi.org/10.1182/blood.V92.3.920

Published: 1998

NARROW

Structural and Functional Characterization of a Codon Optimized Coagulation Factor VIII

Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant

AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage

Codon optimization of human factor VIII cDNAs leads to high-level expression

Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors

O tissue factor, where art thou?

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

FVIIa gene delivery: potential treatment for hemophilia?

Tissue Specific Expression of Alternatively Spliced Forms of Tissue Factor Pathway Inhibitor (TFPI) in Mice

Regenerative repair after endoluminal injury in mice with specific antagonism of protease activated receptors on CD34 + vascular progenitors

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

The Secretion Efficiency of Factor VIII Can Be Regulated by the Size and Oligosaccharide Content of the B Domain.

A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome

Inhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium

Functional characterization of factor V-Ile359Thr: a novel mutation associated with thrombosis

Exclusion of the First EGF Domain of Factor VII by a Splice Site Mutation Causes Lethal Factor VII Deficiency

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American Society of Hematology

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ASH Publications

American Society of Hematology

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