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Jordan S. Fridman
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Journal Articles

FLX925 Is a Rationally Designed FLT3, CDK4/6 Inhibitor with a Desirable Resistance Profile

Sachie Marubayashi, M.S., Adam Park, B.S., Rajkumar Noubade, PhD, Huyen Phan, B.S., Gene Cutler, PhD, Paul Kassner, PhD, Jordan S Fridman, PhD
Journal: Blood
Blood (2016) 128 (22): 2323.
https://doi.org/10.1182/blood.V128.22.2323.2323
Published: 2016
Journal Articles

A Machine-Learning Analysis Suggests That FLX925, a FLT3/CDK4/6 Kinase Inhibitor, Is Potent Against FLT3-Wild Type Tumors Via Its CDK4/6 Activity

Gene Cutler, PhD, Jordan S Fridman, PhD
Journal: Blood
Blood (2016) 128 (22): 3520.
https://doi.org/10.1182/blood.V128.22.3520.3520
Published: 2016
Journal Articles

Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia

Shannon L. Maude, Sarah K. Tasian, Tiffaney Vincent, Junior W. Hall, Cecilia Sheen, Kathryn G. Roberts, Alix E. Seif, David M. Barrett, I-Ming Chen, J. Racquel Collins, Charles G. Mullighan, Stephen P. Hunger, Richard C. Harvey, Cheryl L. Willman, Jordan S. Fridman, Mignon L. Loh, Stephan A. Grupp, David T. Teachey
Journal: Blood
Blood (2012) 120 (17): 3510–3518.
https://doi.org/10.1182/blood-2012-03-415448
Published: 2012
Includes: Supplemental data
Journal Articles

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

Xiangdong Liu, Niu Shin, Holly K. Koblish, Gengjie Yang, Qian Wang, Kathy Wang, Lynn Leffet, Michael J. Hansbury, Beth Thomas, Mark Rupar, Paul Waeltz, Kevin J. Bowman, Padmaja Polam, Richard B. Sparks, Eddy W. Yue, Yanlong Li, Richard Wynn, Jordan S. Fridman, Timothy C. Burn, Andrew P. Combs, Robert C. Newton, Peggy A. Scherle
Journal: Blood
Blood (2010) 115 (17): 3520–3530.
https://doi.org/10.1182/blood-2009-09-246124
Published: 2010
Journal Articles

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms

Alfonso Quintás-Cardama, Kris Vaddi, Phillip Liu, Taghi Manshouri, Jun Li, Peggy A. Scherle, Eian Caulder, Xiaoming Wen, Yanlong Li, Paul Waeltz, Mark Rupar, Timothy Burn, Yvonne Lo, Jennifer Kelley, Maryanne Covington, Stacey Shepard, James D. Rodgers, Patrick Haley, Hagop Kantarjian, Jordan S. Fridman, Srdan Verstovsek
Journal: Blood
Blood (2010) 115 (15): 3109–3117.
https://doi.org/10.1182/blood-2009-04-214957
Published: 2010
Includes: Supplemental data
Journal Articles

Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis

Priya Koppikar, Omar Abdel-Wahab, Cyrus Hedvat, Sachie Marubayashi, Jay Patel, Aviva Goel, Nicole Kucine, Jeffrey R. Gardner, Andrew P. Combs, Kris Vaddi, Patrick J. Haley, Timothy C. Burn, Mark Rupar, Jacqueline F. Bromberg, Mark L. Heaney, Elisa de Stanchina, Jordan S. Fridman, Ross L. Levine
Journal: Blood
Blood (2010) 115 (14): 2919–2927.
https://doi.org/10.1182/blood-2009-04-218842
Published: 2010
Includes: Supplemental data
Journal Articles

The JAK Inhibitor INCB20 Induces Antiproliferative and Apoptotic Effects in Human Myeloma Cells In Vitro and In Vivo .

Renate Burger, PhD, Steven Legouill, MD, Yu-Tzu Tai, PhD, Reshma Shringarpure, PhD, Klaus Podar, MD, PhD, Laurence Catley, MD, Pierfrancesco Tassone, MD, Paola Neri, MD, Teru Hideshima, MD, Dharminder Chauhan, PhD, Eian Caulder, BS, Kris Vaddi, PhD, Claire L. Neilan, PhD, Martin Gramatzki, MD, Jordan S. Fridman, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2005) 106 (11): 3357.
https://doi.org/10.1182/blood.V106.11.3357.3357
Published: 2005
Journal Articles

Inhibition of Human Plasmacytoma Cell Growth by a Novel JAK Kinase Inhibitor.

Renate Burger, PhD, Steven Legouill, MD, Yu-Tzu Tai, PhD, Reshma Shringarpure, PhD, Klaus Podar, MD, PhD, Laurence Catley, MD, Pierfrancesco Tassone, MD, Paola Neri, MD, Teru Hideshima, MD, Dharminder Chauhan, PhD, Jordan S. Fridman, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2004) 104 (11): 644.
https://doi.org/10.1182/blood.V104.11.644.644
Published: 2004