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Kyle Lee
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Journal Articles

Cyproheptadine displays preclinical activity in myeloma and leukemia

Xinliang Mao, Sheng-ben Liang, Rose Hurren, Marcela Gronda, Sue Chow, G. Wei Xu, Xiaoming Wang, Reza Beheshti Zavareh, Nazir Jamal, Hans Messner, David W. Hedley, Alessandro Datti, Jeff L. Wrana, Yuanxiao Zhu, Chang-xin Shi, Kyle Lee, Rodger Tiedemann, Suzanne Trudel, A. Keith Stewart, Aaron D. Schimmer
Journal: Blood
Blood (2008) 112 (3): 760–769.
https://doi.org/10.1182/blood-2008-02-142687
Published: 2008
Includes: Supplemental data
Journal Articles

A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin

Xinliang Mao, A. Keith Stewart, Rose Hurren, Alessandro Datti, Xuegong Zhu, Yuanxiao Zhu, Changxin Shi, Kyle Lee, Rodger Tiedemann, Yanina Eberhard, Suzanne Trudel, Shengben Liang, Seth J. Corey, Lisa C. Gillis, Dwayne L. Barber, Jeffery L. Wrana, Shereen Ezzat, Aaron D. Schimmer
Journal: Blood
Blood (2007) 110 (12): 4047–4054.
https://doi.org/10.1182/blood-2007-05-088666
Published: 2007
Journal Articles

A High Throughput Screen Identified Cyproheptadine That Decreases D-Type Cyclins, Arrests Cells in the G1 Phase, and Induces Apoptosis in Multiple Myeloma and Leukemia Cells.

Xinliang Mao, PhD, A. Keith Stewart, MD, Rose Hurren, BSc, Marcela Gronda, MSc, Kyle Lee, BSc, Sue Chow, BSc, Shengben Liang, PhD, Suzanne Trudel, MD, David W. Hedley, MD, PhD, Aaron D. Schimmer, Md, PhD
Journal: Blood
Blood (2007) 110 (11): 1507.
https://doi.org/10.1182/blood.V110.11.1507.1507
Published: 2007
Journal Articles

A Chemical Biology Screen Identifies Glucocorticoids as Inhibitors of C-Maf and C-Maf-Dependent Transactivation of Cyclin D2.

Xinliang Mao, A. Keith Stewart, Rose Hurren, Alessandro Datti, Chang Xin Shi, Yuan-Xiao Zhu, Kyle Lee, Rodger Tiedemann, Yanina Eberhard, Seth J. Corey, Jeff Wrana, Aaron D. Schimmer
Journal: Blood
Blood (2006) 108 (11): 368.
https://doi.org/10.1182/blood.V108.11.368.368
Published: 2006