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Leonardo Rivadeneyra
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Journal Articles

Activation of pyruvate kinase by mitapivat potentially rescues ineffective erythropoiesis in models of diamond blackfan anemia.

Free
Jonathan R.A. de Wilde, Richard Pozzetto Huot, Veronica Riccardi, Yuefeng Tang, Alexis Bertrand, Riaz Rao, Marion Serra, Naomi Taylor, Vincent Schulz, Patrick Gallagher, Jeffrey Michael Lipton, Roberta Russo, Achille Iolascon, Leonardo Rivadeneyra, Megan Wind-Rotolo, Mohandas Narla, Julien Papoin, Lucia De Franceschi, Lionel Blanc
Journal: Blood
Blood (2025) 146 (Supplement 1): 1121.
https://doi.org/10.1182/blood-2025-1121
Published: 2025
Journal Articles

Long-term mitapivat treatment improves inflammatory pro-fibrotic cardiomyopathy in a murine model of β-thalassemia.

Free
Enrica Federti, Alessandra Ghigo, Tolunay Kavaz, Veronica Riccardi, Richard Pozzetto Huot, Jacopo Ceolan, Simone Villaboni, Angelo D'Alessandro, Federica Logrand, Leonardo Rivadeneyra, Megan Wind-Rotolo, Lucia De Franceschi
Journal: Blood
Blood (2025) 146 (Supplement 1): 727.
https://doi.org/10.1182/blood-2025-727
Published: 2025
Journal Articles

Efficacy and safety of mitapivat in pediatric patients with pyruvate kinase deficiency who are not regularly transfused: Results from the Phase 3, global, randomized, double-blind, placebo-controlled ACTIVATE-Kids trial

Free
Satheesh Chonat, Rachael Grace, Kathryn Dickerson, Oliver Andres, Marije Bartels, Vanessa Beynon, Jenny Despotovic, Bertil Glader, Yoann Huguenin, Janet Kwiatkowski, Erin Laflam, Leonardo Rivadeneyra, Bryan McGee, Ophelia Yin, Thais Murciano Carrillo, Yves Pastore, Jennifer Rothman, Patrick Tyler, Emily Xu, Raffaele Renella, Julian Sevilla
Journal: Blood
Blood (2025) 146 (Supplement 1): 4654.
https://doi.org/10.1182/blood-2025-4654
Published: 2025
Journal Articles

B4galt1 Regulates the WNT-β-Catenin Axis to Control Hematopoietic Stem and Progenitor Cells (HSPCs) Fitness

Free
Alejandro Roisman, Leonardo Rivadeneyra, Lindsey Conroy, Simon Glabere, Grace Kelly, Natalia Weich, George Steinhardt, Shikan Zheng, Anthony Veltri, Joseph T. Lau, Hartmut Weiler, Ramon Sun, Karin M. Hoffmeister
Journal: Blood
Blood (2023) 142 (Supplement 1): 398.
https://doi.org/10.1182/blood-2023-182211
Published: 2023
Journal Articles

B4GALT1-Dependent Glycosylation Is Essential to Bone Marrow Reconstitution Following Chemotherapeutic Injury

Free
Natalia Weich, Leonardo Rivadeneyra, Simon Glabere, Hartmut Weiler, Karin M. Hoffmeister
Journal: Blood
Blood (2023) 142 (Supplement 1): 3933.
https://doi.org/10.1182/blood-2023-182373
Published: 2023
Journal Articles

Clinical impact of glycans in platelet and megakaryocyte biology

Free
Hervé Falet, Leonardo Rivadeneyra, Karin M. Hoffmeister
Journal: Blood
Blood (2022) 139 (22): 3255–3263.
https://doi.org/10.1182/blood.2020009303
Published: 2022
Journal Articles

Immune cells surveil aberrantly sialylated O -glycans on megakaryocytes to regulate platelet count

Free
Melissa M. Lee-Sundlov, Robert T. Burns, Taylor O. Kim, Renata Grozovsky, Silvia Giannini, Leonardo Rivadeneyra, Yongwei Zheng, Simon H. Glabere, Walter H. A. Kahr, Reza Abdi, Jenny M. Despotovic, Demin Wang, Karin M. Hoffmeister
Journal: Blood
Blood (2021) 138 (23): 2408–2424.
https://doi.org/10.1182/blood.2020008238
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Plasmacytoid Dendritic Cells Surveil Megakaryocyte Sialic Acid to Regulate Thrombopoiesis

Free
Melissa M. Lee-Sundlov, PhD, Robert Burns, PhD, Renata Grozovsky, PhD, Silvia Giannini, PhD, Leonardo Rivadeneyra, PhD, Yongwei Zheng, PhD, Simon Glabere, Walter H. Kahr, MDPhDFRCPC, Reza Abdi, Demin Wang, PhD, Karin M. Hoffmeister, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-142737
Published: 2020
Journal Articles

Sialylated Glycans Regulate MUC13 and the Proto-Oncogenes Pim-1 and Myc to Control Hematopoietic Stem and Progenitor Cell Numbers

Free
Leonardo Rivadeneyra, PhD, Melissa M. Lee-Sundlov, PhD, Simon Glabere, Heather Ashwood, Robert Burns, PhD, Karin M. Hoffmeister, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8.
https://doi.org/10.1182/blood-2020-143365
Published: 2020