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Journal Articles

A single-arm, open-label, multi-center, phase 1b/2 Study to evaluate the safety, efficacy, and cellular pharmacokinetic profile of CTD402 in participants with relapsed/refractory T-cell acute lymphoblastic leukemia (T-ALL) and lymphoblastic lymphoma (T-LBL) (TENACITY-01)

Free
Lori Muffly, Edward Abadir, Mark Geyer, Ryan Cassaday, Gregory Roloff, R. Alejandro Sica, Wendy Stock, Eileen McNulty, Maria Del Rosario, Xiao Shi, Yanbo Liu, Yong Yu, Yali Zhou, Ming Gao, Wengang Ge, Lu Han, Yajin Ni, Jiangtao Ren, Jan Davidson-Moncada, Nitin Jain
Journal: Blood
Blood (2025) 146 (Supplement 1): 5954.
https://doi.org/10.1182/blood-2025-5954
Published: 2025
Journal Articles

CD7-targeted universal CAR T-cell therapy in relapsed or refractory (R/R) acute myeloid leukemia (AML): Clinical results from CTD401/402 studies

Free
Yong-xian Hu, Xiaoyu Zhu, Heng Mei, Ying Wang, Yali Zhou, Kangqi Bian, Maria del Rosario, Eileen McNulty, Ming Gao, Lu Han, Wengang Ge, Jan Davidson-Moncada, Jiangtao Ren, He Huang
Journal: Blood
Blood (2025) 146 (Supplement 1): 816.
https://doi.org/10.1182/blood-2025-816
Published: 2025
Journal Articles

CTA311, a universal anti-CD19 CAR t-cell therapy with improved persistence for patients with CD19+ relapsed/ refractory (R/R) b-cell acute lymphoblastic leukemia (B-ALL)

Free
Guangyu Sun, Heng Mei, Anyou Wang, Tianzhong Pan, Yali Zhou, Gong Chen, Jiuqin Zeng, Kangqi Bian, Jan Davidson-Moncada, Bo Pei, Lu Han, Jiangtao Ren, Xiaoyu Zhu
Journal: Blood
Blood (2025) 146 (Supplement 1): 5920.
https://doi.org/10.1182/blood-2025-5920
Published: 2025
Journal Articles

N-homocysteinylation of β-arrestins biases GPCR signaling and promotes platelet activation

Available to Purchase
Lin-Qi Zhang, Chang-Xiao Che, Ya-Qin Du, Lu-Lu Han, Jia-Le Wang, Chen-Yu Zhang, Shen-Ming Huang, Zhong-Yuan Zheng, Qing-Tao He, Zhao Yang, Long Zhang, Nan Chen, Fan Yang, Ying-Li Jia, Shi-Min Zhao, De-Min Zhou, Chu Wang, Xian Wang, Jin-Peng Sun, Lu Tie
Journal: Blood
Blood (2025) 145 (20): 2374–2389.
https://doi.org/10.1182/blood.2024025593
Published: 2025
Includes: Supplemental data
Journal Articles

Phase I Study of Allogeneic Anti-CD19 CAR-T Therapy for Patients with CD19+ Relapsed/Refractory Acute B-Lymphoblastic Leukemia

Free
Guangyu Sun, Heng Mei, Yali Zhou, Tianzhong Pan, Lu Han, Jiangtao Ren, Xiaoyu Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 7199.
https://doi.org/10.1182/blood-2024-200582
Published: 2024
Journal Articles

A Novel Generation of Anti-CD7 Universal CAR-T Therapy for Patients with Relapsed or Refractory CD7 Positive T-ALL/Lbl: A Phase I Clinical Trial

Free
Yongxian Hu, Yali Zhou, Mingming Zhang, Shan Fu, Yong Yu, Ming Gao, Ruimin Hong, Houli Zhao, Lu Han, Jiangtao Ren, He Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 921.
https://doi.org/10.1182/blood-2024-207322
Published: 2024
Journal Articles

A Novel Universal CD7-Targeted CAR-T Cell Therapy for Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia and T-Cell Lymphoblastic Lymphoma

Free
Xian Zhang, Yali Zhou, Junfang Yang, Jingjing Li, Liyuan Qiu, Wengang Ge, Bo Pei, Jie Chen, Lu Han, Jiangtao Ren, Peihua Lu
Journal: Blood
Blood (2022) 140 (Supplement 1): 4566–4567.
https://doi.org/10.1182/blood-2022-165733
Published: 2022
Journal Articles

The Safety and Efficacy of a CRISPR/Cas9-Engineered Universal CAR-T Cell Product (CTA101) in Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia

Free
Yongxian Hu, MD, Yali Zhou, Mingming Zhang, MD, Wengang Ge, Yi Li, MD, Li Yang, MD, Guoqing Wei, MD, Lu Han, Hao Wang, Xingwang Zhang, PhD, Jiangtao Ren, PhD, He Huang, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 52.
https://doi.org/10.1182/blood-2020-142262
Published: 2020
Journal Articles

Autologous Hematopoietic Stem Cell Infusion for Myelosuppression after Bcma-CART Therapy in Relapsed Myeloma Patients

Free
Quande Lin, PhD, Lu Han, MS, Jian Zhou, MD PhD, Lina Liu, Master, Yuzhang Liu, master, Fengkuan Yu, Master, YangLi Zhang, Master, Wenli Zuo, Doctor, Keshu Zhou, MD, Baijun Fang, MD, Quanli Gao, Doctor, Xudong Wei, PhD, Delong Liu, MD PhD, Yongping Song, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1851.
https://doi.org/10.1182/blood-2019-128410
Published: 2019
Journal Articles

Treatment of Epstein-Barr Virus Associated Central Nervous System Diseases after Allogeneic Hematopoietic Stem Cell Transplantation with Intrathecal Donor Lymphocyte Infusion

Free
Juanjuan Zhao, Yingling Zu, Lu Han, Yanli Zhang, Ruirui Gui, Fengkuan Yu, Zhen Li, Huifang Zhao, Baijun Fang, MD, Quande Lin, Yongping Song, MD, Delong Liu, MD PhD, Jian Zhou, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5685.
https://doi.org/10.1182/blood-2018-99-115742
Published: 2018
Journal Articles

Successful Treatment with Intrathecal Tocilizumab(IL-6 antibody) for 2 Cases of Graft-Versus Host Disease of the Central Nervous System after a Second Allogeneic HSCT from Haploidentical Donor

Free
Ruirui Gui, Juanjuan Zhao, Yingling Zu, Lu Han, MS, Yanli Zhang, Fengkuan Yu, Zhen Li, Huifang Zhao, Baijun Fang, MD, Quande Lin, Quanli Gao, MD, Yongping Song, MD, Jian Zhou, MD PhD, Delong Liu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5730.
https://doi.org/10.1182/blood-2018-99-117725
Published: 2018
Journal Articles

Development and Evaluation of CART Targeting Bcma with Humanized Alpaca-Derived Single-Domain Antibody As Antigen Recognition Domain

Free
Lu Han, MS, Quanli Gao, MD, Keshu Zhou, MD, Qingsong Yin, PhD, Baijun Fang, MD, Jian Zhou, MD PhD, Xinghu Zhu, MD, Delong Liu, MD PhD, Jishuai Zhang, PhD, Haoyue Du, Hongjian Li, MS, Yongping Song, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1976.
https://doi.org/10.1182/blood-2018-99-114980
Published: 2018