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Journal Articles

Chromatin Accessibility Analysis Reveals Epigenetic Evolution Is a Common Mechanism of Relapse in Acute Myeloid Leukemia

Kevin A. Nuno, Armon Azizi, Thomas Koehnke, Asiri Ediriwickrema, M. Ryan Corces, Ravi Majeti

Blood (2021) 138 (Supplement 1): 677.

https://doi.org/10.1182/blood-2021-148928

Published: 2021

Journal Articles

Multi-Omic Analysis Identifies Epigenetic Evolution in Relapsed Acute Myeloid Leukemia

Kevin Nuno, BS, Armon Azizi, BS, Thomas Koehnke, MD, M. Ryan Corces, PhD, Ravi Majeti, MD PhD

Blood (2020) 136 (Supplement 1): 13–14.

https://doi.org/10.1182/blood-2020-143141

Published: 2020

Journal Articles

Azacitidine and Ascorbate Inhibit the Competitive Outgrowth of Human TET2 Mutant HSPCs in a Xenograft Model of Pre-Leukemia

Yusuke Nakauchi, MD PhD, Daniel Thomas, MD PhD, Rajiv Sharma, PhD, M. Ryan Corces, PhD, Andreas Reinisch, MD PhD, David Cruz, MS, Thomas Koehnke, MD PhD, Daiki Karigane, MDPhD, Amy Fan, BS, Ravindra Majeti, MD PhD

Blood (2018) 132 (Supplement 1): 887.

https://doi.org/10.1182/blood-2018-99-113907

Published: 2018

Journal Articles

Single-Cell Mutational Profiling of Clonal Evolution in De Novo AML during Therapy and Relapse

Alexey Aleshin, MD MBA, Robert Durruthy-Durruthy, PhD, M. Ryan Corces, PhD, Melissa Stafford, Michaela Liedtke, MD, Bruno C. Medeiros, MD, Dennis J. Eastburn, PhD, Ravindra Majeti, MD PhD

Blood (2018) 132 (Supplement 1): 1469.

https://doi.org/10.1182/blood-2018-99-118089

Published: 2018

Journal Articles

Characterization and Targeting TET2-Mutant HSPCs and AML

Yusuke Nakauchi, MD PhD, Daniel Thomas, MD PhD, Andreas Reinisch, MD PhD, Rajiv Sharma, PhD, David Cruz, BS, M. Ryan Corces, PhD, Ravi Majeti, MD PhD

Blood (2017) 130 (Supplement 1): 2509.

https://doi.org/10.1182/blood.V130.Suppl_1.2509.2509

Published: 2017

Journal Articles

An HPFH Mutation in the γ-Globin Gene Promoter of Humanized Cooley's Anemia Mice Rescues Them from Perinatal Lethality and Renders Them Transfusion Independent

Suean Daimia Fontenard, BS, Yongliang Huo, PhD, Shanrun Liu, MD PhD, Jonathan Lockhart, BS, Michael Berlett, BS, Thomas M Ryan, PhD

Blood (2016) 128 (22): 1290.

https://doi.org/10.1182/blood.V128.22.1290.1290

Published: 2016

Journal Articles

In Vivo Efficacy of Bcl11a Erythroid-Enhancer Deletion in Humanized Mouse Models of Anemia

Thomas M Ryan, PhD, Suean Daimia Fontenard, BS, Shanrun Liu, MD PhD, Jonathan Lockhart, BS, Michael Berlett, BS

Blood (2016) 128 (22): 2465.

https://doi.org/10.1182/blood.V128.22.2465.2465

Published: 2016

Journal Articles

Pluripotent Reprogramming of Human AML Resets Leukemic Behavior and Models Therapeutic Targeting of Subclones

Mark Ping Chao, MD PhD, Gentles Andrew, PhD, Chatterjee Susmita, MS, Andreas Reinisch, MDPhD, M. Ryan Corces, PhD, Jinfeng Shen, PhD, Morganti Rachel, Rahul Singha, PhD, Daniel Haag, PhD, Marius Wernig, PhD, Joseph Wu, MD PhD, Ravi Majeti, MD PhD

Blood (2016) 128 (22): 575.

https://doi.org/10.1182/blood.V128.22.575.575

Published: 2016

Journal Articles

Rescue of a Humanized Mouse Model of β-Thalassemia Major By Allogeneic Bone Marrow Transplantation in the Absence of Cytoreductive Conditioning

Jonathan Lockhart, BS, Yongliang Huo, PhD, Shanrun Liu, MD PhD, Suean Daimia Fontenard, BS, Michael Berlett, BS, Thomas M Ryan, PhD

Blood (2016) 128 (22): 2155.

https://doi.org/10.1182/blood.V128.22.2155.2155

Published: 2016

Journal Articles

Novel Insights into the Clinical Phenotype and Pathophysiology Underlying Low VWF Levels: The Low Von Willebrand Factor in Ireland Cohort (LoVIC) Study

Michelle Lavin, MB FRCPath, Sonia Aguila, PhD, Sonja Schneppenheim, MD, Niall Dalton, BSc, Jamie M O'Sullivan, PhD, Niamh M O'Connell, MB, FRCPath, PhD, Kevin M. Ryan, MB, Mary Byrne, MSc, Margaret Nolan, BSc, Roger Preston, PhD, Ulrich Budde, MD, Paula D. James, MD, Jorge Di Paola, MD, James S O'Donnell, MD PhD

Blood (2016) 128 (22): 873.

https://doi.org/10.1182/blood.V128.22.873.873

Published: 2016

Journal Articles

Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition

Subarna Sinha, Daniel Thomas, Linda Yu, Andrew J. Gentles, Namyoung Jung, M. Ryan Corces-Zimmerman, Steven M. Chan, Andreas Reinisch, Andrew P. Feinberg, David L. Dill, Ravindra Majeti

Blood (2015) 125 (2): 316–326.

https://doi.org/10.1182/blood-2014-03-566018

Published: 2015

Includes: Supplemental data

Journal Articles

Clonal Evolution of Pre-Leukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia

Max Jan, PhD, Thomas M. Snyder, PhD, M. Ryan Corces-Zimmerman, Irving L. Weissman, Stephen R. Quake, PhD, Ravindra Majeti, MD, PhD

Blood (2011) 118 (21): 4.

https://doi.org/10.1182/blood.V118.21.4.4

Published: 2011

Journal Articles

Preclinical transfusion-dependent humanized mouse model of β thalassemia major

Yongliang Huo, Sean C. McConnell, Thomas M. Ryan

Blood (2009) 113 (19): 4763–4770.

https://doi.org/10.1182/blood-2008-12-197012

Published: 2009

Includes: Supplemental data

Journal Articles

Efficient Clonal Gene Delivery into Human Embryonic Stem Cells Via Active Transgenesis Using PiggyBac Transposition.

Ting-Ting Zhang, Clayton L. Ulrey, Shan-Run Liu, Rui Yang, Sean C. McConnell, Yongliang Huo, Thomas M. Ryan

Blood (2007) 110 (11): 5149.

https://doi.org/10.1182/blood.V110.11.5149.5149

Published: 2007

Journal Articles

Erythroid Development in the Absence of Hemoglobin.

Shan-Run Liu, Sean C. McConnell, Yongliang Huo, Ting-Ting Zhang, Rui Yang, Clayton L. Ulrey, Thomas M. Ryan

Blood (2007) 110 (11): 1262.

https://doi.org/10.1182/blood.V110.11.1262.1262

Published: 2007

Journal Articles

Lentiviral Insertion Site Analysis of Corrected Mouse Model of β Thalassemia Following Lentiviral Transduction of Embryonic Stem Cells.

Rui Yang, Sean C. McConnell, Yongliang Huo, Clayton Ulrey, Shan-Run Liu, Ting-Ting Zhang, Thomas M. Ryan

Blood (2007) 110 (11): 2592.

https://doi.org/10.1182/blood.V110.11.2592.2592

Published: 2007

Journal Articles

Human Gamma Globin Gene Regulation in Knock-In Mouse Models of Anemia.

Sean C. McConnell, Yongliang Huo, Shan-Run Liu, Ting-Ting Zhang, Clayton L. Ulrey, Thomas M. Ryan

Blood (2007) 110 (11): 1779.

https://doi.org/10.1182/blood.V110.11.1779.1779

Published: 2007

Journal Articles

A Humanized Cooley’s Anemia Mouse Model.

Yongliang Huo, Sean C. McConnell, Clayton L. Ulrey, Ting-Ting Zhang, Rui Yang, Shan-Run Liu, Thomas M. Ryan, Ph.D.

Blood (2007) 110 (11): 1784.

https://doi.org/10.1182/blood.V110.11.1784.1784

Published: 2007

Journal Articles

Correction of sickle cell disease by homologous recombination in embryonic stem cells

Li-Chen Wu, Chiao-Wang Sun, Thomas M. Ryan, Kevin M. Pawlik, Jinxiang Ren, Tim M. Townes

Blood (2006) 108 (4): 1183–1188.

https://doi.org/10.1182/blood-2006-02-004812

Published: 2006

Journal Articles

Generation of a Novel Mouse Model of Cooley’s Anemia.

Yongliang Huo, Sean McConnell, Chiao-Wang Sun, PhD, Li-Chen Wu, Thomas M. Ryan, PhD

Blood (2005) 106 (11): 3654.

https://doi.org/10.1182/blood.V106.11.3654.3654

Published: 2005

NARROW

Chromatin Accessibility Analysis Reveals Epigenetic Evolution Is a Common Mechanism of Relapse in Acute Myeloid Leukemia

Multi-Omic Analysis Identifies Epigenetic Evolution in Relapsed Acute Myeloid Leukemia

Azacitidine and Ascorbate Inhibit the Competitive Outgrowth of Human TET2 Mutant HSPCs in a Xenograft Model of Pre-Leukemia

Single-Cell Mutational Profiling of Clonal Evolution in De Novo AML during Therapy and Relapse

Characterization and Targeting TET2-Mutant HSPCs and AML

An HPFH Mutation in the γ-Globin Gene Promoter of Humanized Cooley's Anemia Mice Rescues Them from Perinatal Lethality and Renders Them Transfusion Independent

In Vivo Efficacy of Bcl11a Erythroid-Enhancer Deletion in Humanized Mouse Models of Anemia

Pluripotent Reprogramming of Human AML Resets Leukemic Behavior and Models Therapeutic Targeting of Subclones

Rescue of a Humanized Mouse Model of β-Thalassemia Major By Allogeneic Bone Marrow Transplantation in the Absence of Cytoreductive Conditioning

Novel Insights into the Clinical Phenotype and Pathophysiology Underlying Low VWF Levels: The Low Von Willebrand Factor in Ireland Cohort (LoVIC) Study

Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition

Clonal Evolution of Pre-Leukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia

Preclinical transfusion-dependent humanized mouse model of β thalassemia major

Efficient Clonal Gene Delivery into Human Embryonic Stem Cells Via Active Transgenesis Using PiggyBac Transposition.

Erythroid Development in the Absence of Hemoglobin.

Lentiviral Insertion Site Analysis of Corrected Mouse Model of β Thalassemia Following Lentiviral Transduction of Embryonic Stem Cells.

Human Gamma Globin Gene Regulation in Knock-In Mouse Models of Anemia.

A Humanized Cooley’s Anemia Mouse Model.

Correction of sickle cell disease by homologous recombination in embryonic stem cells

Generation of a Novel Mouse Model of Cooley’s Anemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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