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Journal Articles

NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity

Katarina Ochodnicka-Mackovicova, Mahnoush Bahjat, Timon A. Bloedjes, Chiel Maas, Alexander M. de Bruin, Richard J. Bende, Carel J. M. van Noesel, Jeroen E. J. Guikema
Journal: Blood
Blood (2015) 126 (11): 1324–1335.
https://doi.org/10.1182/blood-2015-01-621623
Published: 2015
Includes: Supplemental data
Journal Articles

Impact of interferon-γ on hematopoiesis

Alexander M. de Bruin, Carlijn Voermans, Martijn A. Nolte
Journal: Blood
Blood (2014) 124 (16): 2479–2486.
https://doi.org/10.1182/blood-2014-04-568451
Published: 2014
Journal Articles

Interferon-γ impairs proliferation of hematopoietic stem cells in mice

Alexander M. de Bruin, Özlem Demirel, Berend Hooibrink, Christian H. Brandts, Martijn A. Nolte
Journal: Blood
Blood (2013) 121 (18): 3578–3585.
https://doi.org/10.1182/blood-2012-05-432906
Published: 2013
Includes: Supplemental data
Journal Articles

The Role of Bone Marrow T Cells in Regulating Hematopoietic Stem Cell Function.

Claudia Brandao, MSc, Alexander M. de Bruin, Martijn A. Nolte, PhD
Journal: Blood
Blood (2012) 120 (21): 2349.
https://doi.org/10.1182/blood.V120.21.2349.2349
Published: 2012
Journal Articles

BH3-only protein Noxa regulates apoptosis in activated B cells and controls high-affinity antibody formation

Felix M. Wensveen, Ingrid A. M. Derks, Klaas P. J. M. van Gisbergen, Alex M. de Bruin, Joost C. M. Meijers, HaciAli Yigittop, Martijn A. Nolte, Eric Eldering, René A. W. van Lier
Journal: Blood
Blood (2012) 119 (6): 1440–1449.
https://doi.org/10.1182/blood-2011-09-378877
Published: 2012
Includes: Supplemental data
Journal Articles

IFNγ induces monopoiesis and inhibits neutrophil development during inflammation

Alexander M. de Bruin, Sten F. Libregts, Marijke Valkhof, Louis Boon, Ivo P. Touw, Martijn A. Nolte
Journal: Blood
Blood (2012) 119 (6): 1543–1554.
https://doi.org/10.1182/blood-2011-07-367706
Published: 2012
Includes: Supplemental data
Journal Articles

Interferon-Gamma Impairs the Self-Renewal of Hematopoietic Stem Cells

Alexander M. de Bruin, Berend Hooibrink, Martijn A. Nolte, PhD
Journal: Blood
Blood (2011) 118 (21): 2351.
https://doi.org/10.1182/blood.V118.21.2351.2351
Published: 2011
Journal Articles

Interferon-Gamma Induces Monopoiesis and Inhibits Neutrophil Development During Inflammation

Alexander M. de Bruin, Marijke G. Valkhof, Louis Boon, PhD, Ivo P. Touw, PhD, Martijn A. Nolte, PhD
Journal: Blood
Blood (2011) 118 (21): 1320.
https://doi.org/10.1182/blood.V118.21.1320.1320
Published: 2011
Journal Articles

Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis

Sten F. Libregts, Laura Gutiérrez, Alexander M. de Bruin, Felix M. Wensveen, Petros Papadopoulos, Wilfred van Ijcken, Zeliha Özgür, Sjaak Philipsen, Martijn A. Nolte
Journal: Blood
Blood (2011) 118 (9): 2578–2588.
https://doi.org/10.1182/blood-2010-10-315218
Published: 2011
Includes: Supplemental data
Journal Articles

Chronic IFNγ Production Induces Anemia by Reducing Erythrocyte Lifespan and Inhibiting Erythropoiesis through An IRF-1/PU.1-Axis

Sten F. W. M. Libregts, Laura Gutierrez, PhD, Alexander M. de Bruin, PhD, Felix M. Wensveen, Petros Papadopoulos, PhD, Wilfred van Ijcken, PhD, Zeliha Ozgur, Sjaak Philipsen, PhD, Martijn A. Nolte, PhD
Journal: Blood
Blood (2010) 116 (21): 4234.
https://doi.org/10.1182/blood.V116.21.4234.4234
Published: 2010
Journal Articles

Role for BH3-Only Protein NOXA In Growth-Factor Deprivation and Early Erythropoiesis

Christian R. Geest, PhD, Felix M. Wensveen, PhD, Sten F.W.M. Libregts, PhD, Alex M. de Bruin, PhD, Ingrid A.M. Derks, PhD, Paul G. Ekert, Verena Labi, PhD, Andreas Villunger, PhD, Martijn A. Nolte, PhD, Eric Eldering, PhD
Journal: Blood
Blood (2010) 116 (21): 4235.
https://doi.org/10.1182/blood.V116.21.4235.4235
Published: 2010
Journal Articles

IFNy Regulates the Balance Between Monocyte and Neutrophil Production During Immune Activation.

Alexander M. de Bruin, Ivo Touw, Martijn A. Nolte
Journal: Blood
Blood (2010) 116 (21): 1562.
https://doi.org/10.1182/blood.V116.21.1562.1562
Published: 2010
Journal Articles

Eosinophil differentiation in the bone marrow is inhibited by T cell–derived IFN-γ

Alexander M. de Bruin, Miranda Buitenhuis, Koenraad F. van der Sluijs, Klaas P. J. M. van Gisbergen, Louis Boon, Martijn A. Nolte
Journal: Blood
Blood (2010) 116 (14): 2559–2569.
https://doi.org/10.1182/blood-2009-12-261339
Published: 2010
Journal Articles

Erythropoietin accelerates smooth muscle cell–rich vascular lesion formation in mice through endothelial cell activation involving enhanced PDGF-BB release

Maarten L. Janmaat, Jasper L. T. Heerkens, Alexander M. de Bruin, Anita Klous, Vivian de Waard, Carlie J. M. de Vries
Journal: Blood
Blood (2010) 115 (7): 1453–1460.
https://doi.org/10.1182/blood-2009-07-230870
Published: 2010
Journal Articles

Relevance of pretransfusion incubation of platelets at 37 degrees C

RA de Vries, JG Gerritsen, M de Bruin, JJ Marx, HC Hart, A van de Wiel
Journal: Blood
Blood (1992) 80 (6): 1599–1602.
https://doi.org/10.1182/blood.V80.6.1599.1599
Published: 1992