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Marijke G. Valkhof
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Journal Articles

Deletion of Sbds from Hematopoietic Progenitors Causes Neutropenia in a Mouse Model of Shwachman-Diamond Syndrome By Specifically Blocking Myeloid Lineage Progression at Late Differentiation Stages

Noemi A. Zambetti, Paulina M.H. Van Strien, Marijke G. Valkhof, Maria N. Adisty, Eric M. J. Bindels, PhD, Remco M. Hoogenboezem, Mathijs A. Sanders, MSc, Johanna M. Rommens, PhD, Ivo P. Touw, PhD, Marc H.G.P. Raaijmakers, MD PhD
Journal: Blood
Blood (2014) 124 (21): 355.
https://doi.org/10.1182/blood.V124.21.355.355
Published: 2014
Journal Articles

Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis

Julia Skokowa, Doris Steinemann, Jenny E. Katsman-Kuipers, Cornelia Zeidler, Olga Klimenkova, Maksim Klimiankou, Murat Ünalan, Siarhei Kandabarau, Vahagn Makaryan, Renee Beekman, Kira Behrens, Carol Stocking, Julia Obenauer, Susanne Schnittger, Alexander Kohlmann, Marijke G. Valkhof, Remco Hoogenboezem, Gudrun Göhring, Dirk Reinhardt, Brigitte Schlegelberger, Martin Stanulla, Peter Vandenberghe, Jean Donadieu, C. Michel Zwaan, Ivo P. Touw, Marry M. van den Heuvel-Eibrink, David C. Dale, Karl Welte
Journal: Blood
Blood (2014) 123 (14): 2229–2237.
https://doi.org/10.1182/blood-2013-11-538025
Published: 2014
Includes: Supplemental data
Journal Articles

Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia

Renée Beekman, Marijke G. Valkhof, Mathijs A. Sanders, Paulette M. H. van Strien, Jurgen R. Haanstra, Lianne Broeders, Wendy M. Geertsma-Kleinekoort, Anjo J. P. Veerman, Peter J. M. Valk, Roel G. Verhaak, Bob Löwenberg, Ivo P. Touw
Journal: Blood
Blood (2012) 119 (22): 5071–5077.
https://doi.org/10.1182/blood-2012-01-406116
Published: 2012
Includes: Supplemental data
Journal Articles

Interferon-Gamma Induces Monopoiesis and Inhibits Neutrophil Development During Inflammation

Alexander M. de Bruin, Marijke G. Valkhof, Louis Boon, PhD, Ivo P. Touw, PhD, Martijn A. Nolte, PhD
Journal: Blood
Blood (2011) 118 (21): 1320.
https://doi.org/10.1182/blood.V118.21.1320.1320
Published: 2011
Journal Articles

Methylated Retroviral Integration Mutagenesis (MRIM) in Mice and Comparative Analysis in Human AML Identify Reduced PTP4A3 Expression As a Prognostic Indicator

Renee Beekman, MD, Marijke G. Valkhof, Stefan J. Erkeland, PhD, Erdogan Taskesen, Veronika Rockova, Justine K. Peeters, PhD, Peter Valk, Bob Lowenberg, MD, PhD, Ivo P. Touw, PhD
Journal: Blood
Blood (2011) 118 (21): 746.
https://doi.org/10.1182/blood.V118.21.746.746
Published: 2011